Home Neuronal Signaling Adrenergic Receptor agonist Methoxyphenamine Hydrochloride For research use only.

Methoxyphenamine Hydrochloride

Synonyms: 2-methoxy-N-methylamphetamine Hydrochloride, OMMA Hydrochloride

Methoxyphenamine Hydrochloride (2-methoxy-N-methylamphetamine, OMMA) is a β-adrenergic receptor agonist of the amphetamine class used as a bronchodilator.

Methoxyphenamine Hydrochloride Chemical Structure

Methoxyphenamine Hydrochloride Chemical Structure

CAS: 5588-10-3

Purity & Quality Control

Batch: S364001 DMSO] 43 mg/mL] false] Water] 43 mg/mL] false] Ethanol] 43 mg/mL] false Purity: 99.74%
99.74

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Signaling Pathway

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Biological Activity

Description Methoxyphenamine Hydrochloride (2-methoxy-N-methylamphetamine, OMMA) is a β-adrenergic receptor agonist of the amphetamine class used as a bronchodilator.
In Vivo
In vivo Methoxyphenamine (1 mg kg-1, i.v.) inhibits histamine-induced nasal congestion in the rat. Its sympathomimetic action in reducing histamine-induced nasal congestion is probably mediated, at least in part indirectly, with involvement of α1-adrenoceptors[1].
Animal Research Animal Models Male Wistar rats
Dosages 0.01-30 mg/kg
Administration i.v.

Chemical Information & Solubility

Molecular Weight 215.72 Formula

C11H17N .HCl
CAS No. 5588-10-3 SDF Download Methoxyphenamine Hydrochloride SDF
Smiles CC(CC1=CC=CC=C1OC)NC.Cl
Storage (From the date of receipt)

In vitro
Batch:

DMSO : 43 mg/mL ( (199.33 mM)； Moisture-absorbing DMSO reduces solubility. Please use fresh DMSO.)

Water : 43 mg/mL

Ethanol : 43 mg/mL


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In vivo
Batch:

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In vivo Formulation Calculator

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In vivo Formulation Calculator (Clear solution)

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Method for preparing DMSO master liquid: mg drug pre-dissolved in μL DMSO ( Master liquid concentration mg/mL, Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug. )

Method for preparing in vivo formulation: Take μL DMSO master liquid, next addμL PEG300, mix and clarify, next addμL Tween 80, mix and clarify, next add μL ddH2O, mix and clarify.

Method for preparing in vivo formulation: Take μL DMSO master liquid, next add μL Corn oil, mix and clarify.

Note: 1. Please make sure the liquid is clear before adding the next solvent.
2. Be sure to add the solvent(s) in order. You must ensure that the solution obtained, in the previous addition, is a clear solution before proceeding to add the next solvent. Physical methods such
as vortex, ultrasound or hot water bath can be used to aid dissolving.

Tech Support

Answers to questions you may have can be found in the inhibitor handling instructions. Topics include how to prepare stock solutions, how to store inhibitors, and issues that need special attention for cell-based assays and animal experiments.

Handling Instructions

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