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Epinephrine HCl

Name: Epinephrine HCl
Brand: Selleck Chemicals
SKU: S3061
Rating: 5 (2 reviews)

Synonyms: Adrenaline

Catalog No.S3061 Purity: 99.90%

Epinephrine HCl (Adrenaline) is a hormone and a neurotransmitter.

Epinephrine HCl Chemical Structure

CAS: 55-31-2

Selleck's Epinephrine HCl has been cited by 2 publications

Purity & Quality Control

Batch: Purity: 99.90%

99.90

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Signaling Pathway

Adrenergic Receptor Signaling Pathway

Choose Selective Adrenergic Receptor Inhibitors

Biological Activity

Description

Epinephrine HCl (Adrenaline) is a hormone and a neurotransmitter.

Targets

Adrenergic Receptor ^[1]

In vitro
In vitro	Epinephrine has many functions in the body, regulating heart rate, blood vessel and air passage diameters, and metabolic shifts. Epinephrine release is a crucial component of the fight-or-flight response of the sympathetic nervous system.In chemical terms, epinephrine is one of a group of monoamines called the catecholamines. It is produced in some neurons of the central nervous system, and in the chromaffin cells of the adrenal medulla from the amino acids phenylalanine and tyrosine.

NCT Number	Recruitment	Conditions	Sponsor/Collaborators	Start Date	Phases
Clinical Trial Information (data from https://clinicaltrials.gov, updated on 2024-01-11)
NCT06139809	Not yet recruiting	Infant Newborn Diseases\|Intubation Complication	University of Zurich	January 1 2024	Not Applicable
NCT05849077	Not yet recruiting	Premature Infants\|Bronchopulmonary Dysplasia\|Intraventricular Hemorrhage\|Neurodevelopmental Outcomes	University of Texas Southwestern Medical Center\|University of Alabama at Birmingham\|University of Oklahoma	January 1 2024	Not Applicable
NCT06149091	Recruiting	Iatrogenic Endobronchial Bleeding	China-Japan Friendship Hospital\|The Second Affiliated Hospital of Harbin Medical University\|The First Affiliated Hospital of Nanchang University	December 1 2023	Early Phase 1
NCT06068764	Recruiting	Coronary Artery Disease	Hartford Hospital	December 5 2023	Phase 4
NCT04316611	Not yet recruiting	Out-of-hospital Cardiac Arrest (OHCA)	Assistance Publique - Hôpitaux de Paris\|URC-CIC Paris Descartes Necker Cochin	December 2023	Phase 2

References

Chemical Information & Solubility

Molecular Weight	219.67	Formula	C₉H₁₃NO₃.HCl
CAS No.	55-31-2	SDF	Download Epinephrine HCl SDF
Smiles	CNCC(C1=CC(=C(C=C1)O)O)O.Cl
Storage (From the date of receipt)	3 years-20°Cpowder	Storage of Stock Solutions Aliquot the stock solutions to avoid repeated freeze-thaw cycles	1 year-80°Cin solvent
Storage (From the date of receipt)	3 years-20°Cpowder		1 month-20°Cin solvent

In vitro
Batch:

DMSO : 44 mg/mL ( (200.3 mM)； Moisture-absorbing DMSO reduces solubility. Please use fresh DMSO.)

Water : 44 mg/mL

Ethanol : 22 mg/mL

Molecular Weight Calculator

In vivo
Batch:

Add solvents to the product individually and in order.

In vivo Formulation Calculator

Preparing Stock Solutions

Molarity Calculator

Dilution Calculator Molecular Weight Calculator

In vivo Formulation Calculator (Clear solution)

Step 1: Enter information below (Recommended: An additional animal making an allowance for loss during the experiment)

Dosage: mg/kg Average weight of animals: g Dosing volume per animal:μL Number of animals:

Step 2: Enter the in vivo formulation (This is only the calculator, not formulation. Please contact us first if there is no in vivo formulation at the solubility Section.)

% DMSO + % + % Tween 80 + % ddH₂O

%DMSO+ %

Calculation results:

Working concentration: mg/ml;

Method for preparing DMSO master liquid: mg drug pre-dissolved in μL DMSO ( Master liquid concentration mg/mL, Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug. )

Method for preparing in vivo formulation: Take μL DMSO master liquid, next addμL PEG300, mix and clarify, next addμL Tween 80, mix and clarify, next add μL ddH₂O, mix and clarify.

Method for preparing in vivo formulation: Take μL DMSO master liquid, next add μL Corn oil, mix and clarify.

Note: 1. Please make sure the liquid is clear before adding the next solvent.
2. Be sure to add the solvent(s) in order. You must ensure that the solution obtained, in the previous addition, is a clear solution before proceeding to add the next solvent. Physical methods such
as vortex, ultrasound or hot water bath can be used to aid dissolving.

Tech Support

Answers to questions you may have can be found in the inhibitor handling instructions. Topics include how to prepare stock solutions, how to store inhibitors, and issues that need special attention for cell-based assays and animal experiments.

Handling Instructions

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