Dobutamine HCl

Synonyms: Dobutrex

Dobutamine(Dobutrex) hydrochloride is a selective potent agonist of β1-AR (β-1 adrenergic receptor) and exhibits weak activity at α1-AR and β2-AR. Dobutamine is a sympathomimetic compound that effectively restores blood pressure in hypotensive dogs and human patients by improving myocardial contractility and increasing cardiac output (CO).

Dobutamine HCl Chemical Structure

Dobutamine HCl Chemical Structure

CAS: 49745-95-1

Purity & Quality Control

Batch: Purity: 99.86%
99.86

Dobutamine HCl Related Products

Choose Selective Adrenergic Receptor Inhibitors

Biological Activity

Description Dobutamine(Dobutrex) hydrochloride is a selective potent agonist of β1-AR (β-1 adrenergic receptor) and exhibits weak activity at α1-AR and β2-AR. Dobutamine is a sympathomimetic compound that effectively restores blood pressure in hypotensive dogs and human patients by improving myocardial contractility and increasing cardiac output (CO).
Targets
β1-AR [1]

Chemical Information & Solubility

Molecular Weight 337.84 Formula

C18H23NO3·HCl

CAS No. 49745-95-1 SDF --
Storage (From the date of receipt)

In vitro
Batch:

DMSO : 68 mg/mL ( (201.27 mM); Moisture-absorbing DMSO reduces solubility. Please use fresh DMSO.)

Water : Insoluble

Ethanol : Insoluble


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In vivo
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Method for preparing DMSO master liquid: mg drug pre-dissolved in μL DMSO ( Master liquid concentration mg/mL, Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug. )

Method for preparing in vivo formulation: Take μL DMSO master liquid, next addμL PEG300, mix and clarify, next addμL Tween 80, mix and clarify, next add μL ddH2O, mix and clarify.

Method for preparing in vivo formulation: Take μL DMSO master liquid, next add μL Corn oil, mix and clarify.

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Tech Support

Answers to questions you may have can be found in the inhibitor handling instructions. Topics include how to prepare stock solutions, how to store inhibitors, and issues that need special attention for cell-based assays and animal experiments.

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