Bambuterol HCl

Catalog No.S4277

Bambuterol HCl is a potent β-adrenoceptor agonist, used in the treatment of asthma.

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Bambuterol HCl Chemical Structure

Bambuterol HCl Chemical Structure
Molecular Weight: 403.90

Validation & Quality Control

Quality Control & MSDS

Product Information

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Product Description

Biological Activity

Description Bambuterol HCl is a potent β-adrenoceptor agonist, used in the treatment of asthma.
Targets β-adrenergic receptor [1]
In vitro
In vivo

Conversion of different model animals based on BSA (Value based on data from FDA Draft Guidelines)

SpeciesMouseRatRabbitGuinea pigHamsterDog
Weight (kg)
Body Surface Area (m2)0.0070.0250.
Km factor36128520
Animal A (mg/kg) = Animal B (mg/kg) multiplied by  Animal B Km
Animal A Km

For example, to modify the dose of resveratrol used for a mouse (22.4 mg/kg) to a dose based on the BSA for a rat, multiply 22.4 mg/kg by the Km factor for a mouse and then divide by the Km factor for a rat. This calculation results in a rat equivalent dose for resveratrol of 11.2 mg/kg.

Rat dose (mg/kg) = mouse dose (22.4 mg/kg) ×  mouse Km(3)  = 11.2 mg/kg
rat Km(6)


Clinical Trial Information( data from, updated on 2016-07-30)

NCT Number Recruitment Conditions Sponsor
Start Date Phases
NCT01796730 Completed COPD The First Affiliated Hospital of Guangzhou Medical Univer  ...more The First Affiliated Hospital of Guangzhou Medical University|Nanfang Hospital of Southern Medical University|Guangzhou First Municipal People’s Hospital February 2013 Phase 4
NCT02002754 Recruiting Eosinophilic Bronchitis|Cough Variant Asthma The First Affiliated Hospital of Guangzhou Medical Univer  ...more The First Affiliated Hospital of Guangzhou Medical University June 2012 Phase 4
NCT01566565 Completed High Altitude Pulmonary Hypertension Norwegian Armed Forces Medical Service|Duke University|Os  ...more Norwegian Armed Forces Medical Service|Duke University|Oslo University Hospital March 2012 Phase 1

Chemical Information

Download Bambuterol HCl SDF
Molecular Weight (MW) 403.90


CAS No. 81732-46-9
Storage 3 years -20℃powder
2 years -80℃in solvent
Synonyms N/A
Solubility (25°C) * In vitro DMSO 80 mg/mL (198.06 mM)
Water 72 mg/mL (178.26 mM)
Ethanol 28 mg/mL warming (69.32 mM)
In vivo
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Selleck tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
Chemical Name Carbamic acid, N,N-dimethyl-, 3-[[(dimethylamino)carbonyl]oxy]-5-[2-[(1,1-dimethylethyl)amino]-1-hydroxyethyl]phenyl ester, hydrochloride (1:1)

Tech Support

Answers to questions you may have can be found in the inhibitor handling instructions. Topics include how to prepare stock solutions, how to store inhibitors, and issues that need special attention for cell-based assays and animal experiments.

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Cell Lines Assay Type Concentration Incubation Time Formulation Activity Description PMID
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