Parasite

The ELAVL3/MYCN positive feedback loop provides a therapeutic target for neuroendocrine prostate cancer

32 views | Jan 11 2024

The identification of ELAVL3 as a pivotal regulator in neuroendocrine prostate cancer, its interplay with MYCN, RICTOR mRNA, and extracellular vesicles, coupled with the efficacy of pyrvinium pamoate in suppressing tumor growth and improving survival, presents a promising avenue for targeted therapies and drug repurposing strategies in this aggressive cancer. [Read the Full Post]

Phytochemical characterization, antioxidant activity and antihypertensive evaluation of Ocimum basilicum L. in l-NAME induced hypertensive rats and its correlation analysis

90 views | Jun 05 2023

The study found that Ocimum basilicum Linn. leaves extracts have potential as antihypertensive drugs due to their bioactive metabolites, with phenolic compounds playing a role in inhibiting l-Name induced hypertension and flavonoids contributing to antioxidant activities. [Read the Full Post]