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Endocrinology & Hormones
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Transmembrane Transporters
- CD markers
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Metabolism
- PPAR
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- OXPHOS
- Glutathione
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Proteases
- HDAC
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- MMP
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Microbiology
- HCV Protease
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- Anti-infection
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Others
- ADC Cytotoxin
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- Antineoplastic and Immunosuppressive Antibiotics
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- Antibiotics for Mammalian Cell Culture
- Antibiotics for Plant Cell Culture
- Hydrotropic Agents
- Dyes
- PROTAC
- PROTAC Linker
- E3 ligase Ligand
- Target Protein Ligand
- Others
- Antibody-Drug Conjugate

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MALT

Integrating knowledge of protein sequence with protein function for the prediction and validation of new MALT1 substrates

128 views | Sep 07 2023

The bioinformatics-led substrate discovery workflow, GO-2-Substrates, successfully identified seven new MALT1 substrates, including TANK, TAB3, CASP10, ZC3H12D, ZC3H12B, CILK1, and ILDR2, expanding the known repertoire and providing valuable insights into the function of MALT1. [Read the Full Post]

Inhibition of MALT1 reduces ferroptosis in rat hearts following ischemia/reperfusion via enhancing the Nrf2/SLC7A11 pathway

31 views | May 15 2023

Inhibition of MALT1 can reduce I/R-induced myocardial ferroptosis through enhancing the Nrf2/SLC7A11 pathway, making MALT1 a potential therapeutic target for treating myocardial infarction. [Read the Full Post]