Decarboxylase

Dimeric Lectin Chimeras as Novel Candidates for Gb3-Mediated Transcytotic Drug Delivery through Cellular Barriers

24 views | Nov 19 2023

The study presents a novel dimeric LecA chimera, Di-LecA, paired with the host cell glycosphingolipid Gb3, demonstrating efficient transcytosis across Gb3-positive cellular barriers, offering a promising strategy for targeted drug delivery applications. [Read the Full Post]

Emerging compounds and therapeutic strategies to treat infections from Trypanosoma brucei: an overhaul of the last 5-years patents

28 views | Apr 26 2023

The review covers recent developments in the discovery of new therapeutic options for Human African Trypanosomiasis, including patents related to new antitrypanosomiasis agents, biological targets, vaccines, and formulations, as well as the selectivity and toxicity of natural and synthetic compounds against human cells. [Read the Full Post]