MAP4K

PROTAC targeting cyclophilin A controls virus-induced cytokine storm

36 views | Jan 19 2024

Researchers have developed PROTACs targeting Cyclophilin A (CypA), showing promise in mitigating cytokine storms by reducing proinflammatory cytokine production and improving survival rates in influenza B virus-infected mice. [Read the Full Post]

Traf2 and NCK Interacting Kinase Is a Critical Regulator of Procollagen I Trafficking and Hepatic Fibrogenesis in Mice

115 views | Oct 27 2023

The study identified TNIK as a key kinase involved in procollagen I trafficking and demonstrated its potential as a therapeutic target for hepatic fibrosis. [Read the Full Post]

A new hazard assessment workflow to assess soil contamination from large and artisanal scale gold mining

80 views | Sep 04 2023

The study developed a new workflow model combining spatial mapping, compositional analysis, and geostatistical modeling to identify and assess the contamination levels and potential risks associated with artisanal and small-scale gold mining activities in the Kedougou region, emphasizing the need for comprehensive risk assessments and improved regulation. [Read the Full Post]