Lipase

Repeated Mild Traumatic Brain Injury and JZL184 Produce Sex-Specific Increases in Anxiety-Like Behavior and Alcohol Consumption in Wistar Rats

18 views | Nov 24 2023

Repeated mild traumatic brain injury (rmTBI) increased alcohol consumption in female rats, had varying effects on anxiety-like behavior in males and females, and systemic treatment with JZL184 did not consistently mitigate these behavioral changes, revealing robust sex differences in rmTBI effects. [Read the Full Post]

Vascular lipid droplets formed in response to TNF, hypoxia, or OA: biochemical composition and prostacyclin generation

95 views | Jun 05 2023

The study investigates the role of lipid droplets (LDs) and adipose triglyceride lipase (ATGL)-dependent prostacyclin (PGI2) generation in the response of endothelial cells to proinflammatory stimuli, demonstrating that LDs formation and ATGL-mediated PGI2 generation represent a universal response to vascular proinflammatory insult. [Read the Full Post]