LTR

Effect of budesonide on pulmonary activity of multidrug resistance-associated protein 1 assessed with PET imaging in rats

20 views | Oct 23 2023

Intratracheal aerosolized budesonide, even at a dose approximately five times higher than the maximum clinical dose, did not affect pulmonary MRP1 activity in rats, suggesting no impact on the MRP1-mediated detoxifying capacity of the lungs, while the model MRP1 inhibitor MK571 exhibited a significant inhibitory effect. [Read the Full Post]

Fabricating transdermal film formulations of montelukast sodium with improved chemical stability and extended drug release

67 views | Apr 23 2023

This research developed a transdermal delivery system for Montelukast Sodium using SA and LS-based films as a controlled release drug delivery system, demonstrating the potential to improve bioavailability and providing a better mode of drug delivery for pediatric and elderly patients. [Read the Full Post]