RAAS

[99mTc]Tc-HYNIC-RM2: A potential SPECT probe targeting GRPR expression in prostate cancers

28 views | Jan 12 2024

The study successfully synthesized and evaluated the 99mTc-labeled HYNIC-RM2 probe, demonstrating high affinity, metabolic stability, enhanced tumor uptake, and clear visualization of GRPR-positive prostate cancer tumors via SPECT imaging, affirming its potential as a promising agent for further exploration in targeting GRPR. [Read the Full Post]

Prophylactic Agents for Preventing Cardiotoxicity Induced Following Anticancer Agents: A Systematic Review and Meta-Analysis of Clinical Trials

44 views | Mar 14 2023

This meta-analysis showed that prophylactic treatment with cardio-protective drugs can protect the left ventricular ejection fraction (LVEF) and prevent EF drop in patients undergoing chemotherapy with anthracyclines. [Read the Full Post]

Long-term treatment of spontaneously hypertensive rats with PD123319 and electrophysiological remodeling of left ventricular myocardium

533 views | Jan 20 2019

Ying X et al. showed that long-term treatment with PD123319 worsened the development of myocyte hypertrophy and associated electrophysiological alterations in spontaneously hypertensive rat. [Read the Full Post]