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5-HT Receptor 5-hydroxytryptamine Receptor

5-HT Receptor Antagonists & Agonists (52)

water-soluble

Cat.No. Product Name Information Product Citations Customer Reviews
S2232 Ketanserin (Vulketan Gel) Ketanserin (Vulketan Gel) is specific 5-HT2A serotonin receptor antagonist with a Ki of 2.5 nM for rat and human 5-HT2A.
S1333 Fluoxetine HCl Fluoxetine HCl is an antidepressant of the selective serotonin reuptake inhibitor (SSRI)class.
S2493 Olanzapine (Zyprexa) Olanzapine(Zyprexa) is a high affinity for 5-HT2 serotonin and D2 dopamine receptor antagonist.
S1441 Venlafaxine Venlafaxine is an arylalkanolamine serotonin-norepinephrine reuptake inhibitor (SNRI).
S1615 Risperidone (Risperdal) Risperidone(Risperdal) is an atypical antipsychotic used to treat schizophrenia.
S4109 Lorcaserin HCl
S4112 Desvenlafaxine Succinate
S4113 Desvenlafaxine
S4053 Sertraline HCl Sertraline HCl is a 5-HT antagonist with Ki of 13 nM.
S8021 Vortioxetine (Lu AA21004) hydrobromide Lu-AA21004 is an oral multimodal serotonergic agent, inhibits 5-HT(1A), 5-HT(1B), 5-HT(3A), 5-HT(7) and SERT with IC50 of 15 nM, 33 nM, 3.7 nM, 19 nM and 1.6 nM, respectively.
Cat.No. Product Name Information Product Citations Customer Reviews
S2459 Clozapine (Clozaril) Clozapine (Clozaril) is a potent 5-HT1C receptor antagonist with an IC50 of 110 nM for 5-HT-stimulated phosphoinositide hydrolysis.
S1283 Asenapine Asenapine ihibits adrenergic receptor (α1, α2A, α2B, α2C) with Ki of 0.25-1.2 nM and also inhibits 5-HT receptor (1A, 1B, 2A, 2B, 2C, 5A, 6, 7) with Ki of 0.03-4.0 nM.
S1336 Fluvoxamine maleate Fluvoxamine maleate is a selective serotonin (5-HT) reuptake inhibitor (SSRI).
S2698 RS-127445 RS-127445 is a selective 5-HT2B antagonist with pKi of 9.5 and pIC50 of 10.4.
S3005 Paroxetine HCl Paroxetine is an antidepressant drug of the SSRI type.
S1432 Sumatriptan succinate Sumatriptan succinate is a triptan sulfa drug containing a sulfonamide group for the treatment of migraine headaches.
S1488 Naratriptan HCl Naratriptan (Amerge) is a triptan agent that is used for the treatment of migraine headaches.
S1649 Zolmitriptan (Zomig) Zolmitriptan(Zomig) is a selective serotonin receptor agonist.
S2541 Clomipramine HCl (Anafranil) Clomipramine hydrochloride (Anafranil) is a hydrochloride salt of clomipramine which is a serotonin transporter (SERT), norepinephrine transporter (NET) dopamine transporter (DAT) blocker with Ki of 0.14, 54 and 3 nM, respectively.
S2691 BMY 7378 BMY 7378 is a multiple inhibitors of α2C-adrenoceptor and α1D-adrenoceptor with pKi of 6.54 and 8.2, respectively.
Cat.No. Product Name Information Product Citations Customer Reviews
S2663 WAY-100635 HCl WAY 100635 is a potent and selective 5-HT agonist with IC50 of 0.95 nM.
S2677 BRL-15572 BRL-15572 is a 5-HT1D antagonist with pKi of 7.9.
S1975 Aripiprazole (Abilify) Aripiprazole is a human 5-HT1A receptor partial agonist with a Ki of 4.2 nM.
S2849 SB-269970 HCl SB-269970 HCl is a hydrochloride salt form of SB-269970, which is a 5-HT7 receptor antagonist with pKi of 8.3.
S2875 Prucalopride Prucalopride is a selective, high affinity 5-HT receptor agonistfor 5-HT4a and 5-HT4b with Ki of 2.5 nM and 8 nM, respectively.
S2894 SB-742457 SB-742457 is a highly selective 5-HT6 receptor antagonist with pKi of 9.63.
S1243 Agomelatine Agomelatine is classified as a norepinephrine-dopamine disinhibitor (NDDI) due to its antagonism of the 5-HT2C receptor.
S1245 Dimebon (Latrepirdine) Dimebon is an antihistamine drug.
S1345 Granisetron HCl Granisetron HCl is a serotonin 5-HT3 receptor antagonist
S1385 Mosapride citrate Mosapride is a gastroprokinetic agent that acts as a selective 5HT4 agonist.
Cat.No. Product Name Information Product Citations Customer Reviews
S1390 Ondansetron HCl (Zofran) Ondansetron is a serotonin 5-HT3 receptor antagonist.
S1436 Tianeptine sodium Tianeptine is a selective serotonin reuptake enhancer (SSRE) compound used for treating major depressive episodes.
S1607 Rizatriptan Benzoate (Maxalt) Rizatriptan Benzoate(Maxalt) is a 5-HT1 agonist triptan drug for the treatment of migraine headaches.
S1869 Dapoxetine HCl (Priligy) Dapoxetine hydrochloride is a short-acting novel selective serotonin reuptake inhibitor.
S1898 Tropisetron Tropisetron hydrochloride is a selective 5-HT3 receptor antagonist and α7-nicotinic receptor agonist with an IC50 of 70.1 ± 0.9 nM for 5-HT3 receptor.
S2669 LY310762 LY310762 is a 5-HT1D antagonist with Ki of ~0.2 μM.
S1996 Ondansetron (Zofran) Ondansetron (Zofran) is a serotonin 5-HT3 receptor antagonist used mainly as an antiemetic.
S2582 Trazodone HCl (Desyrel) Trazodone is an antidepressant belonging to the class of serotonin receptor antagonists and reuptake inhibitors for treatment of anxiety disorders.
S2025 Urapidil HCl Urapidil hydrochloride is a hydrochloride salt form of urapidil which is α1-adrenoceptor antagonist and 5-HT1A receptor agonist with pIC50 of 6.13 and 6.4 respectively.
S2084 Duloxetine HCl (Cymbalta) Duloxetine is a serotonin-norepinephrine reuptake inhibitor with Ki of 4.6 nM, used for treatment of major depressive disorder and generalized anxiety disorder (GAD).
Cat.No. Product Name Information Product Citations Customer Reviews
S2106 Azasetron HCl (Y-25130) Azasetron HCl is a selective 5-HT3 receptor antagonist with IC50 of 0.33 nM used in the management of nausea and vomiting induced by cancer chemotherapy.
S2096 Almotriptan malate (Axert) Almotriptan malate (Axert) is a selective 5-hydroxytryptamine1B/1D (5-HT1B/1D) receptor agonist, used for the treatment of Migraine attacks in adults.
S2112 Blonanserin (Lonasen) Blonanserin is a novel atypical antipsychotic agent with potent dopamine D2 (Ki, 14.8 nM) and serotonin 5-HT2(Ki, 3.98 nM) receptors antagonist properties.
S3175 Atomoxetine HCl
S3180 Eletriptan HBr Eletriptan is a selective 5-HT1B and 5-HT1D receptor agonist with Ki of 0.92 nM and 3.14 nM, respectively.
S3183 Amitriptyline HCl Amitriptyline inhibits serotonin receptor, norepinephrine receptor, 5-HT4, 5-HT2 and sigma 1 receptor with IC50 of 3.45 nM, 13.3 nM, 7.31 nM, 235 nM and 287 nM, respectively.
S2860 IEM 1754 Dihydrobromide IEM 1754 dihydrobroMide is a selective AMPA/kainate receptor blockers for GluR1 and GluR3 with IC50 of 6 μM.
S2852 BRL 54443 BRL 54443 is a 5-HT1E and 5-HT1F receptor agonist with pKi of 8.7 and 9.25, respectively.
S3050 Palonosetron HCl Palonosetron HCl is a 5-HT3 antagonist used in the prevention and treatment of chemotherapy-induced nausea and vomiting.
S2865 VUF 10166 VUF10166 is a novel, potent and competitive antagonist to 5-HT3A with Ki of 0.04 nM.
Cat.No. Product Name Information Product Citations Customer Reviews
S2856 SB 271046 SB-271046 is a potent, selective and orally active 5-HT6 receptor antagonist with pKi of 8.9.
S8010 PRX-08066 PRX-08066 is a selective 5-HT2B antagonist with IC50 of 3.4 nM.
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All 5-HT Receptor Antagonists & Agonists
Tags: 5-HT receptor drugs | Serotonin receptor drugs | 5-HT receptor agonist and antagonist drugs | Serotonin receptor antagonist drugs | Serotonin receptor agonist drugs | 5-HT3 receptor antagonist drugs | 5-HT receptor agonist and antagonist clinical trial | 5-HT receptor agonist and antagonist ic50 | 5-HT receptor agonist and antagonist review