Cyclobenzaprine HCl

Catalog No.S4283

Cyclobenzaprine HCl Chemical Structure

Molecular Weight(MW): 311.85

Cyclobenzaprine HCl is a muscle relaxant by blocking pain sensations, used for the treatment of muscle spasms; A 5-HT2 receptor antagonist.

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Biological Activity

Description Cyclobenzaprine HCl is a muscle relaxant by blocking pain sensations, used for the treatment of muscle spasms; A 5-HT2 receptor antagonist.
Targets
5-HT2 receptor [1]

Protocol

Solubility (25°C)

In vitro DMSO 62 mg/mL (198.81 mM)
Water 62 mg/mL (198.81 mM)
Ethanol 62 mg/mL (198.81 mM)

* Please note that Selleck tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.

Chemical Information

Molecular Weight 311.85
Formula

C20H22ClN

CAS No. 6202-23-9
Storage powder
in solvent
Synonyms N/A

Bio Calculators

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Calculate the mass, volume or concentration required for a solution. The Selleck molarity calculator is based on the following equation:

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*When preparing stock solutions, please always use the batch-specific molecular weight of the product found on the via label and MSDS / COA (available on product pages).

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* When preparing stock solutions always use the batch-specific molecular weight of the product found on the vial label and MSDS / COA (available online).

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Clinical Trial Information

NCT Number Recruitment Conditions Sponsor/Collaborators Start Date Phases
NCT02814565 Recruiting Neck Pain|Back Pain|Spasm Takeda October 2016 Phase 3
NCT02642861 Not yet recruiting Liver Cirrhosis Tanta University October 2016 Phase 3
NCT02403687 Enrolling by invitation Arthritis|Tendonitis|Gout|Radiculopathy|Muscle Spasms|Synovitis|Migraine|Headache Express Specialty Pharmacy June 2015 --
NCT01921296 Terminated Sleep Initiation and Maintenance Disorders|Pain Lynn Henry|Damon Runyon Cancer Research Foundation|University of Michigan Cancer Center August 2013 Phase 2
NCT01889173 Completed Healthy Adults Tonix Pharmaceuticals, Inc. June 2013 Phase 1
NCT01587508 Withdrawn Acute Lumbago Eurofarma Laboratorios S.A. May 2013 Phase 3

Tech Support

Answers to questions you may have can be found in the inhibitor handling instructions. Topics include how to prepare stock solutions, how to store inhibitors, and issues that need special attention for cell-based assays and animal experiments.

Handling Instructions

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5-HT Receptor Signaling Pathway Map

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Cell Lines Assay Type Concentration Incubation Time Formulation Activity Description PMID