Risperidone (Risperdal) Chemical Structure
Agomelatine is classified as a norepinephrine-dopamine disinhibitor (NDDI) due to its antagonism of the 5-HT2C receptor.
WAY-100635 is a potent and selective 5-hydroxytryptamine1A antagonist with an IC50 of 0.95 ± 0.12 nM for 5-HT
LY310762 is a potent and selective 5-HT1D serotonin receptor antagonist with an EC50 of 31 nM.
BRL-15572 is a hydrochloride salt form of BRL-15572 which is a selective serotonin receptor subtype 5-HT1D antagonist with an IC50 of 260 μM.
BMY 7378 is a 5-HT1A receptor weak partial agonist/antagonist and α1D-adrenergic receptor antagonist with Ki values of 2.8 and 0.6 μM for cloned rat rat α1A and hamster α1B receptors, respectively.
RS-127445 is a potent, selective and high affinity serotonin 5-HT2B receptor antagonist with a pIC50 of 10.4.
Fingolimod (FTY720) Gilenia is Src-bcr-Abl Inhibitor & S1P receptor agonist with IC50 of 0.137, 10.98 nM for (S)- and (R)- FTY720-phosphate.
ADL5859 HCl is an δ-opioid receptor agonist (Ki=0.84 nM, EC50=20 nM).
Doxazosin is an alpha-1 adrenergic receptor blocker.
Naftopidil Dihydrochloride is an antihypertensive agent.
Risperidone(Risperdal) is an atypical antipsychotic used to treat schizophrenia (including adolescent schizophrenia), schizoaffective disorder, the mixed and manic states associated with bipolar disorder, and irritability in children with autism. This drug has more pronounced serotonin antagonism than dopamine antagonism. It has high affinity for D2 dopaminergic receptors. It has actions at several 5-HT (serotonin) receptor subtypes. [1]
| Molecular Weight (WM): | 410.48 |
|---|---|
| Formula: | C23H27FN4O2 |
| CAS No.: | 106266-06-2 |
| Synonyms: |
R 64 766, Risperdal
|
| Dissolve in (25°C): | DMSO ≥3mg/mL |
| Water <1mg/mL | |
| Ethanol ≥4mg/mL | |
| Storage: | 2 years-20°CPowder |
| 1 week-4°Cin DMSO | |
| 1 month-80°in DMSO |
A collection of 864 bioactive compounds
A collection of 481 inhibitors
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A unique collection of 47 small molecule inhibitors
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