Catalog No.S1996 Synonyms: GR 38032F, GR-C507/75

Ondansetron Chemical Structure

Molecular Weight(MW): 293.36

Ondansetron is a serotonin 5-HT3 receptor antagonist used mainly as an antiemetic.

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  • Mean (±SEM) cumulative 5-HT concentration–response curves in the absence and presence of 5-HT antagonists (n = >8). Responses are expressed as a percentage of the maximum response for each curve.

    Int J Urol, 2016, 23(11):946-951. Ondansetron purchased from Selleck.

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Choose Selective 5-HT Receptor Inhibitors

Biological Activity

Description Ondansetron is a serotonin 5-HT3 receptor antagonist used mainly as an antiemetic.
5-HT3 [1]



Solubility (25°C)

In vitro DMSO 0.1 mg/mL (0.34 mM)
Water Insoluble
Ethanol Insoluble

* Please note that Selleck tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.

Chemical Information

Molecular Weight 293.36


CAS No. 99614-02-5
Storage powder
Synonyms GR 38032F, GR-C507/75

Bio Calculators

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Molarity Calculator

Calculate the mass, volume or concentration required for a solution. The Selleck molarity calculator is based on the following equation:

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

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*When preparing stock solutions, please always use the batch-specific molecular weight of the product found on the via label and MSDS / COA (available on product pages).

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Dilution Calculator

Calculate the dilution required to prepare a stock solution. The Selleck dilution calculator is based on the following equation:

Concentration (start) x Volume (start) = Concentration (final) x Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2 ( Input Output )

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* When preparing stock solutions always use the batch-specific molecular weight of the product found on the vial label and MSDS / COA (available online).

The Serial Dilution Calculator Equation

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  • Computed Result

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Definitions of molecular mass, molecular weight, molar mass and molar weight:

Molecular mass (molecular weight) is the mass of one molecule of a substance and is expressed in the unified atomic mass units (u). (1 u is equal to 1/12 the mass of one atom of carbon-12)
Molar mass (molar weight) is the mass of one mole of a substance and is expressed in g/mol.

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Mass Concentration Volume Molecular Weight

Clinical Trial Information

NCT Number Recruitment Conditions Sponsor/Collaborators Start Date Phases
NCT03052361 Not yet recruiting Gastroenteritis St. Justines Hospital June 2017 Phase 2|Phase 3
NCT03023462 Not yet recruiting Inguinal Hernia|Pain, Postoperative Ostfold Hospital Trust February 2017 Phase 4
NCT02991456 Not yet recruiting Chemo-radiation Induced Nausea and Vomiting Duke University|Tesaro, Inc. January 2017 Phase 2
NCT03022240 Recruiting Cognitive Change|Behavior University of Calgary January 2017 Phase 4
NCT02987985 Not yet recruiting Anesthesia|General Anesthesia|Analgesics, Opioid|Postoperative Complications|Pathologic Processes|Physiologic Effects of Drugs|Narcotics|Analgesics|Sleep Disordered Breathing|Obstructive Sleep Apnea of Child|Tonsillectomy|Respiratory Depression|Dexmedetomidine|Ketamine|Lidocaine|Gabapentin|Pulse Oximetry University of Saskatchewan January 2017 Phase 3
NCT02928601 Not yet recruiting Maternal Hypotension Cukurova University November 2016 Phase 4

Tech Support

Answers to questions you may have can be found in the inhibitor handling instructions. Topics include how to prepare stock solutions, how to store inhibitors, and issues that need special attention for cell-based assays and animal experiments.

Handling Instructions

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5-HT Receptor Signaling Pathway Map

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Cell Lines Assay Type Concentration Incubation Time Formulation Activity Description PMID