Alverine Citrate
Catalog No.S3054 Synonyms: NSC 35459
Molecular Weight(MW): 473.56
Alverine citrate is a drug used for functional gastrointestinal disorders.
Purity & Quality Control
Biological Activity
| Description | Alverine citrate is a drug used for functional gastrointestinal disorders. |
|---|---|
| In vitro |
In pharmacological studies, alverine citrate has been shown to exert an effect on intestinal motility and intestinal sensitivity, two factors recognized as involved in the onset of FBD, without exhibiting the potential drawbacks of a medication with systemic effects.Alverine citrate affects basal and stimulated motility via a calcium-dependent and -independent inhibition of neuronal excitability as well as direct inactivation of L-type Ca2+ of smooth muscle cells. Experimental findings support an antinociceptive action by selective receptor-mediated mechanisms. |
Protocol
Solubility (25°C)
| In vitro | DMSO | 95 mg/mL (200.6 mM) |
|---|---|---|
| Water | Insoluble | |
| Ethanol | Insoluble |
* Please note that Selleck tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
Chemical Information
| Molecular Weight | 473.56 |
|---|---|
| Formula | C20H27N.C6H8O7 |
| CAS No. | 5560-59-8 |
| Storage | powder |
| Synonyms | NSC 35459 |
Bio Calculators
Molarity Calculator
Calculate the mass, volume or concentration required for a solution. The Selleck molarity calculator is based on the following equation:
Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)
*When preparing stock solutions, please always use the batch-specific molecular weight of the product found on the via label and MSDS / COA (available on product pages).
Dilution Calculator
Calculate the dilution required to prepare a stock solution. The Selleck dilution calculator is based on the following equation:
Concentration (start) x Volume (start) = Concentration (final) x Volume (final)
This equation is commonly abbreviated as: C1V1 = C2V2 ( Input Output )
* When preparing stock solutions always use the batch-specific molecular weight of the product found on the vial label and MSDS / COA (available online).
Molecular Weight Calculator
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Definitions of molecular mass, molecular weight, molar mass and molar weight:
Molecular mass (molecular weight) is the mass of one molecule of a substance and is expressed in the unified atomic mass units (u). (1 u is equal to 1/12 the mass of one atom of carbon-12)
Molar mass (molar weight) is the mass of one mole of a substance and is expressed in g/mol.
Molarity Calculator
Clinical Trial Information
| NCT Number | Recruitment | Conditions | Sponsor/Collaborators | Start Date | Phases |
|---|---|---|---|---|---|
| NCT01404923 | Completed | Irritable Bowel Syndrome | Laboratoires Mayoly Spindler | December 2009 | Phase 4 |
| NCT00542295 | Completed | Irritable Bowel Syndrome | Laboratoires Mayoly Spindler | July 2007 | Phase 4 |
Tech Support
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