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5-HT Receptor

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Isoform-selective Products

Cat.No. Product Name Information Product Use Citations Product Validations
S1333 Fluoxetine Hydrochloride (LY-110140) Fluoxetine HCl is a selective serotonin-reuptake inhibitor (SSRI) at the neuronal membrane, used in the treatment of depression.
Cell Rep, 2024, 43(10):114818
Int Immunopharmacol, 2024, 128:111524
Front Psychiatry, 2023, 14:1198502
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S2493 Olanzapine Olanzapine (LY170053,Zyprexa, Zalasta, Zolafren, Olzapin, Oferta, Zypadhera) is a high affinity for 5-HT2 serotonin and D2 dopamine receptor antagonist.
CNS Neuroscience & Therapeutics, September 2019, 911-921
Biomolecules, November 15, 2025, 1603
Cell Communication and Signaling, July 25, 2024, 375
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S1975 Aripiprazole Aripiprazole (OPC-14597) is a novel atypical antipsychotic drug that is reported to be a high-affinity 5-HT receptor partial agonist.
Mol Psychiatry, 2025, 10.1038/s41380-025-03374-6
Biomol Ther (Seoul), 2025, 33(1):170-181
J Dev Biol, 2025, 13(3)22
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S2459 Clozapine Clozapine (HF 1854, LX 100-129) is an atypical antipsychotic drug by acting as a 5-HT antagonist, used in the treatment of schizophrenia.
Alzheimers & Dementia, May 23, 2023, 5482-5497
Clinical & Experimental Metastasis, January 25, 2025, 12
Clin Exp Metastasis, 2025, 42(2):12
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S4244 Serotonin Hydrochloride (5-HT HCl) Serotonin (5-HT) HCl is a monoamine neurotransmitter and Endogenous 5-HT receptor agonist.
EMBO Mol Med, 2025, 10.1038/s44321-025-00293-5
Anim Biosci, 2025, 38(8):1633-1643
Mod Pathol, 2022, 10.1038/s41379-022-01110-x
S2663 WAY-100635 Maleate WAY-100635 Maleate is a potent and selective 5-HT receptor antagonist with IC50 of 0.95 nM.
PLoS One, January 13, 2017, e0168964
Scientific Reports, April 29, 2021, 9300
Medicine & Science in Sports & Exercise, April 1, 2022, 566-581
Verified customer review of WAY-100635 Maleate
S2346 Puerarin Puerarin (Kakonein), an isoflavones found in the root of Radix puerariae, is a 5-HT2C receptor and benzodiazepine site antagonist.
Acta Biochim Biophys Sin (Shanghai), 2024, 56(2):270-279
Int J Mol Sci, 2023, 24(9)8328
Ecotoxicol Environ Saf, 2022, 247:114239
S1283 Asenapine maleate Asenapine maleate (Org 5222) is a high-affinity antagonist of serotonin, norepinephrine, dopamine and histamine receptors, used for the treatment of schizophrenia and acute mania associated with bipolar disorder.
Anticancer Research, February 2021, 687-697
Anticancer Research, February 15, 2021, 687-697
bioRxiv, February 07, 2026, nan
S4749 Citalopram HBr Citalopram HBr (Nitalapram HBr, Prepram HBr, Bonitrile HBr, Lu 10-171 HBr), an antidepressant, is an orally administered selective serotonin reuptake inhibitor (SSRI) with IC50 of 1.8 nM.
Aging (Albany NY), May 22, 2020, 10147-10161
Scientific Reports, January 13, 2021, 1250
eLife, February 9, 2026, RP103016
S2232 Ketanserin Ketanserin (R41468, Ketanserinum) is a specific 5-HT2A serotonin receptor antagonist with Ki of 2.5 nM for rat and human 5-HT2A, used as an antihypertensive drug.
J Immunother Cancer, 2025, 13(6)e011088
Lab Invest, 2021, 1-14
Int Immunopharmacol, 2019, 10.1016/j.intimp.2019.106036
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