| S2271 |
Berberine chloride
|
Berberine chloride is a quaternary ammonium salt from the group of isoquinoline alkaloids. This compound activates caspase 3 and caspase 8, cleavage of poly ADP-ribose polymerase (PARP) and the release of cytochrome c. It decreases the expression of c-IAP1, Bcl-2 and Bcl-XL. This chemical induces apoptosis with sustained phosphorylation of JNK and p38 MAPK, as well as generation of the ROS. It is a dual topoisomerase I and II inhibitor. It is also a potential autophagy modulator.
|
-
J Cardiovasc Dev Dis, 2025, 12(7)278
-
Adv Healthc Mater, 2023, e2300591.
-
Transl Oncol, 2023, 35:101712
|
|
| S2613 |
Clorsulon
|
Clorsulon (MK-401,L631529) is used in the treatment of Fasciola hepatica infections in calves and sheep.
|
-
iScience, 2024, 27(10):110862
-
J Pers Med, 2022, 12(2)258
-
Hum Cell, 2022, 10.1007/s13577-022-00671-y
|
|
| S4147 |
Azithromycin Dihydrate
|
Azithromycin Dihydrate(CP-62993 dihydrate) is an acid stable orally administered macrolide antimicrobial drug, structurally related to erythromycin.
|
-
J Cell Biochem, 2022, 10.1002/jcb.30213
-
Adv Ther (Weinh), 2020, 2000034
-
PLoS Comput Biol, 2020, 16(12):e1008489
|
|
| S7896 |
Sodium Tauroursodeoxycholate (TUDC)
|
Sodium Tauroursodeoxycholate (TUDC) is a water soluble bile salt, used for the treatment of gallstones and liver cirrhosis.
|
-
iScience, 2024, 27(8):110598
-
Infect Immun, 2024, 92(8):e0030024
-
Microbiome, 2019, 7(1):145
|
|
| S4237 |
Primaquine Diphosphate
|
Primaquine Diphosphate is a transmission-blocking anti-malarial clinically available, displaying a marked activity against gametocytes of all species of human malaria.
|
-
J Extracell Vesicles, 2024, 13(7):e12494
-
bioRxiv, 2024, 2024.10.28.620521
-
Front Pharmacol, 2021, 12:695009
|
|
| S4420 |
Mefloquine HCl
|
Mefloquine HCl(Mefloquin hydrochloride) is a blood schizonticide by inhibiting hemozoin formation, used as an antimalarial drug.
|
-
Mol Med Rep, 2021, 23(1)40
-
bioRxiv, 2020, 2020/9/20.4.7.30734
-
Int J Parasitol Drugs Drug Resist, 2018, 8(2):331-340
|
|
| S5397 |
Chlorhexidine
|
Chlorhexidine is a disinfectant and topical anti-infective agent that is active against Gram-positive and Gram-negative organisms, facultative anaerobes, aerobes, and yeasts.
|
-
Cell Commun Signal, 2024, 22(1):615
-
J Cell Mol Med, 2021, 10.1111/jcmm.16673
-
BMC Microbiol, 2020, 20(1):275
|
|
| S3695 |
Cystamine dihydrochloride
|
Cystamine dihydrochloride (Decarboxycystine, 2-Aminoethyl disulfide, 2,2'-Dithiobisethanamine) acts as an anti-infective agent, which is used in the treatment of urinary tract infections and also as a radiation-protective agent that interferes with sulfhydryl enzymes.
|
-
Free Radic Biol Med, 2025, 237:631-649
-
J Pharmacol Exp Ther, 2025, 392(7):103620
-
Acta Biochim Biophys Sin (Shanghai), 2024, 57(4):616-632
|
|
| S4759 |
p-Coumaric Acid
|
p-Coumaric acid (4-Hydroxycinnamic acid, P-Hydroxycinnamic acid, 4-Coumaric acid, Trans-p-Coumaric acid, para-Coumaric Acid) is a hydroxy derivative of cinnamic acid found in a variety of edible plants and is reported to have antioxidant, anti-inflammatory, and antimicrobial activity.
|
-
Molecules, 2025, 30(11)2458
-
Exp Ther Med, 2021, 21(5):503
-
J Nutr Biochem, 2015, 26(11):1379-84
|
|
| S7411 |
Ascomycin (FK520)
|
Ascomycin (FK520, FR 900520, Immunomycin), an FK-506 analog, is a neutral macrolide immunosuppressant that prevents rejection after an organ transplant. Phase 3.
|
-
ACS Nano, 2024, 18(45):31451-31465
-
Melanoma Res, 2020, 30(4):325-335
-
Virol Sin, 2019, 34(6):648-661
|
|
| S4041 |
Olsalazine Sodium
|
Olsalazine Sodium is an anti-inflammatory prodrug, which consists of two 5-ASA moieties linked by an azo bond.
|
-
Croatica Chemica Acta, 2021, 94(1), 25–33
-
Oncotarget, 2017, 8(1):228-237
|
|
| S2282 |
Cinchonidine
|
Cinchonidine is an alkaloid used in asymmetric synthesis in organic chemistry.
|
-
CNS Neurosci Ther, 2023, 10.1111/cns.14403
-
J Med Virol, 2019, 91(8):1440-1447
|
|
| S5967 |
Berberine chloride hydrate
|
Berberine (Natural Yellow 18) chloride hydrate is a quaternary ammonium salt from the group of isoquinoline alkaloids. Berberine activates caspase 3 and caspase 8, cleavage of poly ADP-ribose polymerase (PARP) and the release of cytochrome c. Berberine chloride decreases the expression of c-IAP1, Bcl-2 and Bcl-XL. Berberine chloride induces apoptosis with sustained phosphorylation of JNK and p38 MAPK, as well as generation of the ROS. Berberine chloride is a dual topoisomerase I and II inhibitor. Berberine chloride is also a potential autophagy modulator.
|
-
Front Biosci (Landmark Ed), 2022, 27(8):242
-
Front Pharmacol, 2021, 12:632201
|
|
| S4172 |
Cetylpyridinium Chloride
|
Cetylpyridinium chloride(CPC) is a cationic quaternary ammonium compound used as oropharyngeal antiseptic.
|
-
iScience, 2024, 27(8):110598
-
Int J Mol Sci, 2023, 24(11)9708
|
|
| S4192 |
Chlorquinaldol
|
Chlorquinaldol(Chloquinan) is an antimicrobial agent used for local antisepsy.
|
-
Biosensors (Basel), 2023, 13(6)571
-
ACS Synth Biol, 2022, 11(8):2820-2828
|
|
| S5961 |
Prednisolone disodium phosphate
|
Prednisolone disodium phosphate (Hydeltrasol, Prednisolone 21-phosphate disodium) is a synthetic glucocorticoid with anti-inflammatory and immunomodulating properties that exerts late mitogenic and biphasic effects on resistant acute lymphoblastic leukemia cells.
|
-
J Immunotoxicol, 2021, 18(1):154-162
-
Eur J Rheumatol, 2021, 10.5152/eurjrheum.2021.20054
|
|
| S3746 |
Lumefantrine
|
Lumefantrine (benflumetol) is an antimalarial agent used to treat acute uncomplicated malaria.
|
-
Antimicrob Agents Chemother, 2021, AAC.02137-20
-
ACS Infect Dis, 2020, 10.1021/acsinfecdis.0c00522
|
|
| S4242 |
Cetrimonium Bromide (CTAB)
|
Cetrimonium Bromide (CTAB) is a known component of the broad-spectrum antiseptic cetrimide, which is a mixture of different quaternary ammonium salts.
|
-
Biochem Cell Biol, 2021, 10.1139/bcb-2020-0570
-
Micromachines (Basel), 2018, 9(6)
|
|
| S9185 |
Nitidine Chloride
|
Nitidine Chloride, a benzophenanthridine alkaloid found in species of the genus Zanthoxylum, has an anti-malarial activity.
|
-
Int Immunopharmacol, 2021, 101(Pt A):108273
-
Front Cell Neurosci, 2020, 14:216
|
|
| S3067 |
Chlorhexidine 2HCl
|
Chlorhexidine hydrochloride (NSC-185) is an antiseptic effective against a wide variety of gram-negative and gram-positive organisms.
|
-
BMC Microbiol, 2020, 20(1):275
|
|
| S2537 |
Secnidazole
|
Secnidazole (Flagentyl, PM 185184, RP 14539) is a nitroimidazole anti-infective.
|
-
Microorganisms, 2022, 10(7)1421
|
|
| S4195 |
Broxyquinoline
|
Broxyquinoline (Dibromohydroxyquinoline) is an antiprotozoal agent and able to release oxygen free radicals from the water in mucous membranes.
|
-
ACS Synth Biol, 2022, 11(8):2820-2828
|
|
| S4196 |
Ethacridine lactate monohydrate
|
Ethacridine lactate monohydrate(Acrinol monohydrat) is an aromatic organic compound based on acridine used as an antiseptic agent.
|
-
Carcinogenesis, 2014, 35(12):2822-30
|
|
| S4726 |
Lauric Acid
|
Lauric Acid (dodecanoic acid, N-Dodecanoic acid, Dodecylic acid) is a saturated medium-chain fatty acid with a 12-carbon backbone. Lauric acid is found naturally in various plant and animal fats and oils, and is a major component of coconut oil and palm kernel oil.
|
-
Nat Commun, 2023, 14(1):660
|
|
| S6288 |
Chlorhexidine diacetate
|
Chlorhexidine diacetate (Hibitane diacetate) is a disinfectant and topical anti-infective agent used also as mouthwash to prevent oral plaque.
|
-
BMC Microbiol, 2020, 20(1):275
|
|
| S9094 |
Pogostone
|
Pogostone is one of the secondary metabolites from Pogostemon cablin (Blanco) Benth. (Lamiaceae), serving as the effective component of the antimicrobial activity.
|
-
J Ethnopharmacol, 2021, 278:114250
|
|
| S5700 |
Phthalylsulfathiazole
|
Phthalylsulfathiazole (Sulfathalidine) is a broad-spectrum antimicrobial that can treat different types of infections including intestinal.
|
-
Med Oncol, 2024, 41(8):188
|
|
| S2395 |
Rheochrysidin
|
Rheochrysidin (Physcione) is an anthraquinone from roots of Rheum officinale Baill.
|
-
ACS Chem Biol, 2015, 10.1021/cb5009487
|
|
| S4081 |
Sulfacetamide Sodium
|
Sulfacetamide Sodium is an anti-biotic.
|
-
G3 (Bethesda), 2020, 4;10(5):1585-1597
|
|
| S9387 |
Maackiain
|
Maackiain (Demethylpterocarpin) is a pterocarpan that is widely distributed in leguminous plants. It has anticancer and antimicrobial effects.
|
-
Int Immunopharmacol, 2022, 108:108710
|
|
| S2564 |
Cloxacillin Sodium
|
Cloxacillin Sodium(Cloxacap,BRL 1621 sodium salt) is a sodium salt of cloxacillin that is a penicillinase-resistant, acid resistant, semi-synthetic penicillin.
|
-
J Immunother Cancer, 2024, 12(11)e009805
|
|
| S5096 |
SulfadiMethoxine sodium
|
Sulfadimethoxine (Sulfadimethoxydiazine) is a long-lasting sulfonamide antimicrobial agent used to treat many infections including treatment of respiratory, urinary tract, enteric, and soft tissue infections.
|
-
Cell Death Dis, 2018, 9(6):646
|
|
| S5214 |
Imidocarb dipropionate
|
Imidocarb is an antiprotozoal agent, used as dipropionate in the treatment of babesiosis and ehrlichiosis.
|
-
Nat Commun, 2017, 8(1):823
|
|
| S1644 |
Nitrofural
|
Nitrofural (Nitrofurazone) is a topical anti-infective agent with an IC50 of 22.83 ± 1.2 μM. (Rat LD50 = 590 mg/kg)
|
|
|
| S2469 |
Fleroxacin
|
Fleroxacin (Ro 23-6240,AM-833,Quinodis, Megalocin) is a new broad-spectrum fluoroquinolone.
|
|
|
| S3116 |
Sulfathiazole
|
Sulfathiazole is an organosulfur compound that has been used as a short-acting sulfa drug.
|
|
|
| S2511 |
Sulfadoxine
|
Sulfadoxine (Sulphadoxine) is an ultra-long-lasting sulfonamide with an IC50 of 249 μg/ml for P. vivax.
|
|
|
| S4191 |
Betamipron
|
Betamipron (CS-443,N-Benzoyl-β-alanine) is a chemical compound which is used together with panipenem to inhibit panipenem uptake into the renal tubule and prevent nephrotoxicity.
|
|
|
| S2612 |
Ribitol
|
Ribitol (Adonitol) is a crystalline pentose alcohol and is formed by the reduction of ribose which is occurs naturally in the plant Adonis vernalis.
|
|
|
| E0525 |
Colistin
|
Colistin(Polymyxin E), a cyclic polypeptide antibiotic synthesized by Bacillus polymyxa subspecies colistinus Koyama, exerts antimicrobial activity by targeting at the bacterial cell membrane.
|
|
|
| E8272New |
Dihydroarteannuin B
|
Dihydroarteannuin B is a cadinane sesquiterpene isolated from the dried leaves of Artemisia annua acts as a microbial metabolite of arteannuin B. It can be used in research for developing malaria treatments.
|
|
|
| S9564 |
p-Hydroxy-cinnamic Acid
|
p-Hydroxy-cinnamic Acid has in vitro antimalarial activity and in vivo anti-osteoporotic properties.
|
|
|
| E3085 |
Dichroae Radix Extract
|
Dichroae Radix Extract is drawed from Dichroae radix, exhibits good clinical efficacy in treatments as an antimalarial, expectorant or antifebrile agent in Chinese medicine, and it also has an anticoccidial effect in chickens infected by coccidiosis when used alone or as the main herb to formulate a complex.
|
|
|
| S4142 |
Clopidol
|
Clopidol (WR 61112) is an antiprotozoal agent.
|
|
|
| S5757 |
Isoeugenol
|
Isoeugenol (4-Propenylguaiacol), an essential oil constituent of nutmeg, clove, and cinnamon, shows antimicrobial activity.
|
|
|
| S0320 |
Cycloguanil hydrochloride
|
Cycloguanil hydrochloride, an active metabolite of proguanil, acts on malaria schizonts in erythrocytes and hepatocytes.
|
|
|
| S4250 |
Sulfamethoxypyridazine
|
Sulfamethoxypyridazine (CL 13494) is a long-acting sulfonamide for treatment of Dermatitis herpetiformis.
|
|
|
| S6173 |
Amylmetacresol
|
Amylmetacresol is an antiseptic used to treat infections of the mouth and throat.
|
|
|
| S5475 |
Novaluron
|
Novaluron (Rimon) belongs to the class of insecticides called insect growth regulators with pesticide properties.
|
|
|
| S3218 |
Amiloxate
|
Amiloxate (Amiloxiate, Isoamyl Methoxycinnamate, Isopentyl 4-methoxycinnamate, Isoamyl 4-methoxycinnamate, Isoamyl p-methoxycinnamate, Isopentyl p-methoxycinnamate) is EMA-approved chemical UV-filter used in cosmetics. This compound is a cinnamic acid derivative with anti-inflammatory activity.
|
|
|
| S5963 |
Sulfathiazole sodium
|
Sulfathiazole sodium, an antimicrobial agent, is an organosulfur compound that has been used as a short-acting sulfa drug.
|
|
|
| S4175 |
Sulfaguanidine
|
Sulfaguanidine is a sulfonamide used as an anti-infective agent. This compound is commonly employed in the treatment of gastrointestinal infections due to its efficacy against certain bacterial strains. It works by inhibiting the growth and reproduction of bacteria, thereby helping to control the spread of infection. The use of this chemical has been well-documented in veterinary medicine as well.
|
|
|
| S3787 |
Picroside I
|
Picroside I (6'-Cinnamoylcatalpol), an iridoid glycoside, is a hepatoprotective agent which is reported to be antimicrobial and used against hepatitis B.
|
|
|
| S9016 |
Dipsacoside B
|
Dipsacoside B, extracted from the flowerbuds of Lonicera confusa DC, shows strong antimicrobial activity.
|
|
|
| S5908 |
Garenoxacin
|
Garenoxacin (T-3811ME, BMS-284756) is a novel des-F(6) quinolone that has been shown to be effective in vitro against a wide range of clinically important pathogens, including gram-positive and gram-negative aerobes and anaerobes.
|
|
|
| E3166 |
Fermented Blank Bean Extract
|
Fermented Blank Bean Extract is extracted from the fermented Phaseolus vulgaris L., and aids in protection of the human digestive tract, mainly the colon.
|
|
|
| S4062 |
Ronidazole
|
Ronidazole is an antiprotozoal agent. This compound is commonly used in veterinary medicine to treat infections caused by protozoa. The efficacy of this chemical has been well-documented in various studies. It is important to note that this agent should be administered under professional guidance to ensure safety and effectiveness.
|
|
|
| S4971 |
Buparvaquone
|
Buparvaquone (Butalex) is a second-generation hydroxynaphthoquinone related to parvaquone, with novel features that make it a promising compound for the therapy and prophylaxis of all forms of theileriosis.
|
|
|
| S6761 |
Dalfopristin
|
Dalfopristin (RP54476) is a semi-synthetic analogue of ostreogyrcin A. Quinupristin/dalfopristin (Q/D) is a parental streptogramin with a spectrum of activity that includes Gram-positive pathogens, including those resistant to other classes of antimicrobial compounds.
|
|
|
| S5292 |
Diazolidinyl urea
|
Diazolidinyl urea (Germall II) is an antimicrobial preservative used in cosmetics.
|
|
|
| E3350 |
Goodyera kwangtungensis Tso. extract
|
Goodyera kwangtungensis Tso. Extract is obtained from Goodyera kwangtungensis C.L. Tso, the entire plant is used to improve the condition of the lungs and to clear phlegm.
|
|
|
| S3210 |
3'-Hydroxy-4'-methoxyacetophenone
|
3'-Hydroxy-4'-methoxyacetophenone (Acetoisovanillone, Isoacetovanillone, Diosmin EP Impurity A) is an active P. spinosa extract with anti-inflammatory potential.
|
|
|
| S5887 |
Khellin
|
Khellin (Methafrone, Visammin, Ammivisnagen, Khellinorm, Medekellin, Viscardan, Kalangin), a compound isolated from the seeds of Ammi Visnaga Lam (Umbelliferae), is used to treat a variety of maladies.
|
|
|
| E0820 |
OX02983
|
OX02983 is a novel anthelmintic agent, actives against both egg and adult stages of Trichuris parasites, immobilising whipworm and reducing the ability of embryonated Trichuris muris eggs to establish infection in the mouse host.
|
|
|
| E6014 |
Primaquine
|
Primaquine, an 8-aminoquinoline, is an antimalarial agent and a potent gametocytocidal in falciparum malaria. It also prevents relapse in vivax and ovale malaria.
|
|
|
| S0146 |
Broxaldine
|
Broxaldine (Brobenzoxaldine, AL307) is an antiprotozoal drug and can be used in leprosy.
|
|
|
| E2137 |
WAY-297407
|
WAY-297407 is a bioactive compound.
|
|
|
| E0749 |
Coumalic acid
|
Coumalic acid is a valuable platform compound which can be prepared from malic acid, can be used in the flavours, fragrances and cosmetics industries, as polymer components, and as pharmaceutical scaffolds displaying anti-bronchial and -malarial activity.
|
|
|
| E2812 |
Antimalarial agent 1
|
Antimalarial agent 1 is a potent antimalarial drug.
|
|
|
| E0938 |
Brincidofovir
|
Brincidofovir (CMX001), the lipid-conjugated prodrug of Cidofovir with long-acting antiviral effect, shows activity against a broad spectrum of DNA viruses including cytomegalovirus (CMV), adenovirus (ADV), varicella zoster virus, herpes simplex virus, polyomaviruses, papillomaviruses, poxviruses, and mixed double-stranded DNA virus infections.
|
|
|
| S3801 |
Sodium Lauryl Sulfoacetate
|
Sodium Lauryl Sulfoacetate, the active compound of the Houttuynia plant, is mainly used for treating purulent skin infections, respiratory tract infections, including pneumonia in elderly patients, and chronic bronchitis.
|
|
|
| S6442 |
Chlorphenesin
|
Chlorphenesin is a synthetic preservative used in skin care as a cosmetic biocide.
|
|
|
| S9342 |
1,4-Naphthoquinone
|
1,4-Naphthoquinone (α-Naphthoquinone, para-naphthoquinone, P-Naphthoquinone), found in diesel exhaust particles and it is an active metabolite of naphthalene, is a fumigant insecticide.
|
|
|
| S6458 |
Isavuconazonium sulfate
|
Isavuconazonium sulfate (BAL8557-002), the prodrug of the active triazole Isavuconazole, is an orally active antifungal agent, using for invasive aspergillosis and mucormycosis.
|
|
|
| S6459 |
Nifurtimox
|
Nifurtimox (BAY-2502) is an antiprotozoal agent.
|
|
|
| S4232 |
Nithiamide
|
Nithiamide (CL 5279) is a non-5-nitroimidazole drugs.
|
|
|
| S3618 |
Acetylspiramycin (ASPM)
|
Acetylspiramycin (ASPM, Spiramycin II, Foromacidin B) is a macrolide antimicrobial agent.
|
|
|
| E3740 |
Isodon serra Extract
|
Isodon Serra Extract is obtained from Isodon serra (Maxim.) Hara, which processes antitumour, anti-angiogenic, analgesic, antitubercular, anti-inflammatory, antibacterial and anti-ischemic activities.
|
|
|
| E3744 |
Prunella Vulgaris Extract
|
Prunella Vulgaris Extract is obtained from Prunella vulgaris, which is a medicinal herb that has been used for centuries to treat infections and other illnesses
|
|
|
| S4236 |
Proflavine Hemisulfate
|
Proflavine Hemisulfate is a topical antiseptic by interchelating DNA, thereby disrupting DNA synthesis and leading to high levels of mutation in the copied DNA strands.
|
|
|
| S5212 |
Imidazolidinyl Urea
|
Imidazolidinyl Urea (Imidurea) is an antimicrobial agent used as preservative in cosmetics.
|
|
|
| S5210 |
Sulfamethazine Sodium Salt
|
Sulfamethazine (Sulfadimethyldiazine) is a sulfanilamide anti-infective agent used in the lifestock industry.
|
|
|
| S0443 |
Desciclovir
|
Desciclovir (DCV, 6-Deoxyacyclovir, BW A515U) is a prodrug of the antiherpetic agent acyclovir (ACV) that converted into ACV by xanthine oxidase in humans.
|
|
|
| S0889 |
Dixanthogen
|
Dixanthogen is an ectoparasiticide.
|
|
|
| S5405 |
Propylparaben
|
Propylparaben (Propyl 4-hydroxybenzoate, Propyl p-hydroxybenzoate, nipasol), a natural substance found in many plants and some insects, is an antimicrobial, preservative and flavouring agent.
|
|
|
| E4946 |
Tafenoquine Succinate
|
Tafenoquine Succinate(WR 238605 Succinate, Etaquine, Krintafel) is an 8-aminoquinoline (8AQ) anti-malarial drug that kills both the liver and blood stages of the parasite, broadening its applicability for chemoprophylaxis to all species of malaria. It is specifically used for the prevention of Plasmodium vivax relapse.
|
|
|
| S3978 |
5-Phenyl-2,4-pentadienoic acid
|
5-Phenyl-2,4-pentadienoic acid (5-Phenylpenta-2,4-dienoic acid) is used as Synthetic building block, anti-malarial agent.
|
|
|
| S5390 |
N-(Hytroxymethy)micotinamide
|
N-(Hydroxymethyl)nicotinamide (Nikomethamide, Bilamid, N-hydroxymethylnicotinamide) is an antimicrobial agent.
|
|
|
| S5355 |
Piperaquine phosphate
|
Piperaquine phosphate is an orally active bisquinolone antimalarial drug.
|
|
|
| S5005 |
Cefotiam hydrochloride
|
Cefotiam hydrochloride (Halospor, Pansporin, Pansporine) is the hydrochloride salt form of cefotiam and has a broad spectrum of activity against both gram-positive and gram-negative microorganisms.
|
|
|
| S1962 |
Sulphadimethoxine
|
Sulphadimethoxine is a non-reducing glucuronide.
|
|
|
| S4555 |
Carsalam
|
Carsalam (Carbonylsalicylamide) is a nonsteroidal anti-inflammatory drug.
|
|
|
| S4521 |
DEET
|
DEET (N,N-Diethyl-meta-toluamide, diethyltoluamide) is a commen active ingredient insect repellent.
|
|
|
| E2971 |
Influenza Hemagglutinin (HA) Peptide
|
Influenza Hemagglutinin (HA) Peptide is a synthetic peptide with an amino acid sequence of N-Tyr-Pro-Tyr-Asp-Val-Pro-Asp-Tyr-Ala-C. It is extensively used to isolate, purify, detect, and track the protein of interest in cell biology and biochemistry. It is used for competing out the anti-HA antibody binding to HA-tagged fusion proteins in immunoassays. It may also be used to to elute HA-tagged fusion proteins from an affinity column of Monoclonal Anti-HA agarose.
|
|
|
| S4592 |
SBE-β-CD
|
SBE-β-CD is a novel, chemically modified cyclodextrin with a structure designed to optimize the solubility and stability of drugs.
|
-
Autophagy, 2025, 21(8):1824-1842
-
Int J Mol Sci, 2025, 26(2)490
-
Front Pharmacol, 2025, 16:1625798
|
|
| S2264 |
Artemether
|
Artemether (SM-224, CGP 56696) is an antimalarial for the treatment of resistant strains of falciparum malaria.
|
-
iScience, 2024, 27(10):110862
-
J Pers Med, 2022, 12(2)258
-
Hum Cell, 2022, 10.1007/s13577-022-00671-y
|
|
| S2479 |
Lincomycin HCl
|
Lincomycin hydrochloride (Lincocin, NSC 70731,U10149A) is the monohydrated salt of lincomycin, a substance produced by the growth of a member of the lincolnensis group of Streptomyces lincolnensis.
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-
iScience, 2024, 27(10):110862
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J Pers Med, 2022, 12(2)258
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Hum Cell, 2022, 10.1007/s13577-022-00671-y
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| S1282 |
Artemisinin
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Artemisinin is a sesquiterpene endoperoxide which is a potent antimalarial agent.
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Virus Res, 2024, 349:199448
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Drug Des Devel Ther, 2023, 17:1679-1697
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Cancer Cell, 2022, S1535-6108(22)00312-9
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| S3649 |
Ceftazidime
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Ceftazidime(GR20263) is a third-generation cephalosporin that has activity against Gram-negative bacilli, including Pseudomonas aeruginosa.
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Infect Drug Resist, 2025, 18:3947-3956
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Mol Cancer, 2024, 23(1):242
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Pharmacol Res, 2024, 201:107096
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| S9131 |
Punicalagin
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Punicalagin, a major ellagitannin found in pomegranate extracts, has been shown to have antioxidant, anti-inflammatory, and anticancer effects., This compound, a major ellagitannin found in pomegranate extracts, has been shown to have antioxidant, anti-inflammatory, and anticancer effects.
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SLAS Discov, 2024, S2472-5552(24)00007-8
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Cell, 2020, 30;181(3):637-652.e15.
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Cell, 2020, 30;181(3):637-652e15
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| S3220 |
Trigonelline
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Trigonelline (Trigenolline) is a plant alkaloid and a major component of coffee and fenugreek with anti-degranulation, anti-diabetic, antioxidant, anti-inflammatory, and neuroprotective effects. This compound inhibits FcεRI-mediated intracellular signaling pathways, such as phosphorylation of PLCγ1, PI3K, and Akt. It also inhibits the microtubule formation in RBL-2H3 cells.
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Int J Med Sci, 2025, 22(5):1194-1207
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Biochem Biophys Rep, 2025, 42:102021
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Biomed Pharmacother, 2021, 143:112204
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| S3941 |
Pinocembrin
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Pinocembrin (Dihydrochrysin, Galangin flavanone, 5,7-Dihydroxyflavanone) is a major flavonoid molecule incorporated as multifunctional in the pharmaceutical industry. Its vast range of pharmacological activities has been well researched including antimicrobial, anti-inflammatory, antioxidant, and anticancer activities.
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Neurol Res, 2022, 1-10
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J Neuroinflammation, 2020, 17(1):337
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| S6185 |
Arachidonic acid
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Arachidonic acid (Arachidonate) is an unsaturated, essential fatty acid found in animal and human fat as well as in the liver, brain, and glandular organs. It is a precursor in the biosynthesis of prostaglandins, thromboxanes, and leukotrienes.,
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Cell Commun Signal, 2025, 23(1):352
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Bone Res, 2022, 10(1):20
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| S6243 |
Ethyl pyruvate
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Ethyl pyruvate (CTI-01) is a simple aliphatic ester of pyruvic acid and has been shown to have robust neuroprotective effects via its anti-inflammatory, anti-oxidative, and anti-apoptotic functions.
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BMC Gastroenterol, 2024, 24(1):245
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| E0524 |
Spinosad
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Spinosad, a mixture of spinosyns A and D known as fermentation products of a soil actinomycete, is a biological neurotoxic insecticide with a broader action spectrum, targeting the nicotinic acetylcholine receptor (nAChRs) of the insect nervous system.
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| E3107 |
Andrographis Herba Extract
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Andrographis Herba Extract is obtained from the aerial part of Andrographis paniculata (Burm. F.) Nees, has various activities including antimicrobial and antioxidant, antimalarial, antiangiogenic, anti-inflammatory, anti-diabetic, and in vitro α-glucosidase and α-amylase enzyme inhibitory activities.
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| S6136 |
(±)-α-Bisabolol
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α-bisabolol is a small, plant-derived, oily sesquiterpene alcohol with some anti-inflammatory and even anti-microbial properties.
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| S9084 |
Rhoifolin
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Rhoifolin (Rhoifoloside, Apigenin 7-O-neohesperidoside, Apigenin-7-O-rhamnoglucoside), a natural glycoside of apigenin, has been obtained from the green leaves of Rhus succedanea and possesses a variety of significant biological activities including antioxidant, anti-inflammatory, antimicrobial, hepatoprotective and anticancer effects.
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| E3695 |
Hypericum japonicum Extract
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Hypericum Japonicum Extract is obtained from the entire herb of Hypericum japonicum, has been widely used for the treatment of bacterial diseases, infectious hepatitis, acute and chronic hepatitis, gastrointestinal disorder, internal hemorrhage and tumour.
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| E2665 |
Tafenoquine
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Tafenoquine (WR 238605) is an 8-aminoquinoline, used as an anti-malarial prophylactic agent.
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| S9112 |
Kaempferitrin
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Kaempferitrin (Lespenefril, Lespedin, Lespenephryl, Kaempferol 3,7-dirhamnoside), isolated from the leaves of Hedyotis verticillata and from Onychium japonicum, has antimicrobial, antioxidant, and anti-inflammatory activities.
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| S9113 |
Ononin
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Ononin (Formononetin glucoside, Formononetin 7-O-glucoside) is an isoflavone glycoside with anti-inflammtory effects.
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| S4678 |
Povidone iodine
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Povidone iodine (Betadine, PVP iodine, PVP-I, Isodine) is a stable chemical complex of polyvinylpyrrolidone (povidone, PVP) and elemental iodine. This compound displays excellent antibacterial activity against MRSA and MSSA strains with MICs of 31.25 mg/L and 7.82 mg/L, respectively. It is used as a topical antiseptic in surgery and for skin and mucous membrane infections, as well as as an aerosol.
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| E3772 |
Eyebright Extract
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Eyebright Extract is extracted from Herba Euphrasiae (Scrophulariaceae), which includes anti-inflammatory, antioxidant, antimicrobial, anticancer, antifungal, antiviral, hypotensive, hapatoprotector, anti-epileptic, and anti-catarrhal activities.
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| S9560 |
Anisodamine Hydrobromide
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Anisodamine (6-Hydroxyhyoscyamine) is a naturally occurring atropine derivative and exhibits anti-inflammatory activity. It also inhibits α1-adrenergic receptors and muscarinic acetylcholine receptors (mAChRs).
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