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Anti-infection Inhibitors

Cat.No. Product Name Information Product Use Citations Product Validations
S1553 Delafloxacin (ABT-492) Delafloxacin (ABT-492, RX-3341, WQ-3034) is a new fluoroquinolone against 155 aerobic and 171 anaerobic pathogens.
Molecules, 2023, 28(6)2820
Molecules, 2023, 28(6), 2820
S5927 Proguanil Proguanil (chlorguanide, chloroguanide) is a prophylactic antimalarial drug. It inhibits the dihydrofolate reductase of plasmodia and thereby blocks the biosynthesis of purines and pyrimidines, which are essential for DNA synthesis and cell multiplication.
Int J Med Sci, 2022, 19(2):233-241
Sci Adv, 2021, 7(27)eabh3032
S4945 Ethacridine lactate Ethacridine lactate (Acrinol) is an aromatic organic compound based on acridine used as an antiseptic agent. This compound is also a poly(ADP-ribose) glycohydrolase (PARG) inhibitor.
Stem Cell Res Ther, 2025, 16(1):489
S3226 Dehydroabietic acid Dehydroabietic acid (DAA, DHAA), a naturally occurring diterpene resin acid derived from coniferous plants such as Pinus and Picea, displays anti-inflammatory activity via suppression of Src-, Syk-, and TAK1-mediated pathways.
S3308 Caftaric acid Caftaric acid (CA, Caffeoyl tartaric acid) is a natural product that shows anti-oxidant and anti-inflammatory effects.
S4946 2,3-Dihydroxybenzoic acid 2,3-Dihydroxybenzoic acid (Pyrocatechuic acid, 3-Hydroxysalicylic acid, Hypogallic acid) is a natural phenol found in Phyllanthus acidus and in the aquatic fern Salvinia molesta, also a product of human aspirin metabolism. It is a potentially useful iron-chelating drug and has antimicrobial properties.
E0626 AX 20017 AX 20017 is a small-molecule protein kinase G (PknG) inhibitor with an IC50 of 0.39 μM.
S4303 9-Aminoacridine 9-Aminoacridine (Aminacrine) is a highly fluorescent dye used clinically as a topical antiseptic and experimentally as a mutagen, an intracellular pH indicator and a negative mode small molecule MALDI matrix.
S4417 Ceftaroline Fosamil

Ceftaroline fosamil (CX-0903, DSP-5990, PPI-0903, TAK-599, Teflaro, Zinforo) is a cephalosporin with activity against Gram-positive pathogens, including methicillin-resistant Staphylococcus aureus (MRSA).
S0846 Euquinine Euquinine is generally used as a febrifuge, antimalarial, and tonic.
S6771 MAC-545496 MAC-545496 is a nanomolar glycopeptide-resistance-associated protein R(GraR) inhibitor with strong binding affinity to the full-length GraR protein (Kd ≤ 0.1 nM). This compound can reverse β-lactam resistance in methicillin-resistant strains and synergize with CAMPs. It shows remarkable activity in macrophages and attenuates S. aureus virulence in a G. mellonella larvae infection model.
S3711 Carbasalate Calcium Carbasalate calcium (Iromin, Alcacyl, Omegin, Rheomin, Solupsan) is an analgesic, antipyretic, and anti-inflammatory drug as well as a platelet aggregation inhibitor.
E1126 AFN-1252 AFN-1252 (Debio 1452) is a potent inhibitor of enoyl-acyl carrier protein reductase (FabI), inhibits all clinical isolates of Staphylococcus aureus and Staphylococcus epidermidis at concentrations of ≤0.12 μg/ml.
E1421 A2ti-1 A2ti-1 is a selective and high-affinity inhibitor of annexin A2/S100A10 heterotetramer (A2t) with IC50 of 24 μM. This compound specifically disrupts the protein-protein interaction (PPI) between A2 and S100A10. It also prevents human papillomavirus type 16 (HPV16) infection.
E7151 Mephenytoin Mephenytoin is an antiepileptic drug, can be used as a probe for the estimation of the metabolic activities of CYP2B6 and CYP2C19. It can be used in antimalarial research.
S9341 3,4-Dimethoxycinnamic acid 3,4-Dimethoxycinnamic acid (Caffeic acid dimethyl ether) is a bioavailable coffee component as a perspective anti-prion compound and bind potently to prion protein with a Kd of 405 nM.
S4515 Ademetionine disulfate tosylate Ademetionine Disulfate Tosylate is the disulfate-tosylate mixed salt of a mixture of diastereoisomers of the ademetionine ions. Ademetionine possesses anti-inflammatory activity and has been used in treatment of chronic liver disease.
S6802 Etosalamide Etosalamide (Ethosalamide) is an anti-inflammatory drug with antipyretic and analgesics properties.
E0516 Nequinate Nequinate, a quinoline compound, is an anticoccidial agent against cecal coccidiosis (Eimeria tenella) infections, also inhibits xanthine oxidoreductase (XOD) activity.This product has poor solubility, animal experiments are available, cell experiments please choose carefully!
E1436 A2ti-2 A2ti-2 is a selective and low-affinity inhibitor of annexin A2/S100A10 heterotetramer (A2t)with an IC50 of 230 μM. It specifically disrupts the protein-protein interaction (PPI) between A2 and S100A10 and also prevents human papillomavirus type 16 (HPV16) infection.
S1958 Sulbactam Sulbactam(CP45899) is a beta-lactamase inhibitor with an average IC50 of 0.8 μM.
S4157 Chloroquine diphosphate Chloroquine diphosphate is a 4-aminoquinoline anti-malarial and anti-rheumatoid agent, also acting as an ATM activator. Chloroquine is also an inhibitor of toll-like receptors (TLRs).
Front Vet Sci, 2025, 12:1587391
Nat Commun, 2024, 15(1):1642
Cancer Lett, 2024, 604:217258
Verified customer review of Chloroquine diphosphate
S5001 CP-690550 (Tofacitinib) Citrate Tofacitinib citrate (CP-690550, Tasocitinib) is a novel JAK inhibitor with IC50 of 1 nM, 20 nM and 112 nM against JAK3, JAK2, and JAK1, respectively. It also has anti-infection activity.
Cells, 2025, 14(2)102
Front Pharmacol, 2025, 16:1549183
J Exp Clin Cancer Res, 2024, 43(1):64
Verified customer review of CP-690550 (Tofacitinib) Citrate
S4430 HCQ (Hydroxychloroquine) Sulfate Hydroxychloroquine (HCQ) Sulfate is an antimalarial agent used for the treatment of systemic lupus erythematosus, rheumatoid arthritis and other autoimmune, inflammatory and dermatologic conditions. Also acts as an inhibitor of autophagy and toll-like receptor (TLR) 7/9.
EMBO J, 2025, 10.1038/s44318-025-00581-3
iScience, 2025, 28(4):112054
Int J Mol Sci, 2025, 26(2)588
Verified customer review of HCQ (Hydroxychloroquine) Sulfate
S8279 (±)-Shikonin (±)-Shikonin, a potent and specific Pyruvate kinase M2 (PKM2) inhibitor, is a major component of zicao (purple gromwell, the dried root of Lithospermum erythrorhizon), a Chinese herbal medicine with various biological activities. It is also an inhibitor of TMEM16A chloride channel activity using cell-based fluorescent-quenching assay. Shikonin exerts an anti-inflammatory effect by inhibiting tumor necrosis factor-α (TNF-α) and prevents activation of nuclear factor-κB (NF-κB) pathway via proteasome inhibition.
Signal Transduct Target Ther, 2025, 10(1):341
J Exp Clin Cancer Res, 2025, 44(1):299
Free Radic Biol Med, 2025, 237:65-75
S8068 Chaetocin Chaetocin, a natural product from Chaetomium species, is a histone methyltransferase inhibitor with IC50 of 0.8 μM, 2.5 μM and 3 μM for dSU(VAR)3-9, mouse G9a and Neurospora crassa DIM5, respectively. Chaetocin is an anticancer agent and inhibitor of thioredoxin reductase (TrxR).
Research (Wash D C), 2025, 8:0602
Cell Rep, 2025, 44(6):115742
Int J Mol Sci, 2024, 25(17)9215
S7465 FTI 277 HCl FTI 277 HCl is a potent and selective farnesyltransferase (FTase) inhibitor with IC50 of 500 pM, about 100-fold selectivity over the closely related GGTase I. This compound inhibits cell growth and induces apoptosis. This chemical is effective in clearing HDV viremia.
EMBO J, 2025, 44(4):1185-1219
BMC Biol, 2025, 23(1):233
PLoS One, 2025, 20(9):e0331440
Verified customer review of FTI 277 HCl
S2572 Streptomycin sulfate Streptomycin sulfate(Phytomycin) is a sulfate salt of streptomycin that is a protein synthesis inhibitor.
Front. Oncol, 2023-, Volume 13
Front Oncol, 2023, 13:1118268
Transl Oncol, 2022, 26:101502
S5184 Dexamethasone palmitate Dexamethasone palmitate (DXP), a lipophilic prodrug of Dexamethasone (DXM), is a glucocorticoid receptor agonist with a 47-fold lower affinity for the glucocorticoid receptor than DXM. This compound exhibits anti-inflammatory activity.
Dis Model Mech, 2022, dmm.049109
Hematology, 2022, 27(1):32-42
S7867 Oleuropein Oleuropein is an antioxidant polyphenol isolated from olive leaf. It exerts antioxidant, anti-inflammatory and anti-atherogenic effects and suppresses the adipocyte differentiation in vitro. This compound inhibits PPARγ activity. It exerts anti-adipogenic effect through direct inhibition of PPARγ transcriptional activity. This chemical also inhibits aromatase. It induces apoptosis. Phase 2.
Front Endocrinol (Lausanne), 2024, 15:1354435
J Med Virol, 2019, 91(8):1440-1447
E0206 Ginkgetin

Ginkgetin is a biflavone from Ginkgo biloba leaves with anti-cancer, anti-inflammatory, anti-microbial, anti-adipogenic, and neuroprotective activities.
Biomed Pharmacother, 2022, 154:113628
S3261 Myrislignan Myrislignan, a lignan isolated from Myristica fragrans Houtt, possesses anti-inflammatory activities. This compound inhibits interleukin-6 (IL-6) and tumour necrosis factor-α (TNF-α). It significantly inhibits the expressions of inducible NO synthase (iNOS) and cyclooxygenase-2 (COX-2) dose-dependently in LPS-stimulated macrophage cells. It also inhibits the NF-κB signalling pathway activation.
Oxid Med Cell Longev, 2023, 2023:7098313