STAT

  • Compare STAT Products
  • Research Area

STAT Inhibitors (7)

water-soluble

Cat.No. Product Name Information Product Citations Customer Reviews
S1155 S3I-201 S3I-201 shows potent inhibition of STAT3 DNA-binding activity with IC50 of 86 μM, and low activity towards STAT1 and STAT5.
  • Cancer Discov, 2013, 3(2):158-67
  • Mol Cancer, 2011, 10:66
  • Mol Cancer, 2014, 13:176
S1491 Fludarabine Fludarabine is a STAT1 activation inhibitor and a DNA synthesis inhibitor.
  • J Biol Chem, 2014, 289(14):9952-60
S7024 Stattic Stattic, the first nonpeptidic small molecule, potently inhibits STAT3 activation and nuclear translocation with IC50 of 5.1 μM, highly selectivity over STAT1.
  • J Biol Chem, 2013, 288(8):5553-61
S3030 Niclosamide Niclosamide can inhibit DNA replication and inhibit STAT with IC50 of 0.7 μM.
S2285 Cryptotanshinone Cryptotanshinone (CPT) is a STAT3 inhibitor with IC50 of 4.6 μM, strongly inhibits phosphorylation of STAT3 Tyr705, with a small effect on STAT3 Ser727, but none against STAT1 nor STAT5.
S7337 SH-4-54 SH-4-54 is a potent STAT inhibitor with KD of 300 nM and 464 nM for STAT3 and STAT5, respectively.
S7501 HO-3867 HO-3867, an analog of curcumin, is a selective STAT3 inhibitor.
Tags: STAT inhibition | STAT signaling pathway | STAT pathway | STAT cancer | STAT signaling | STAT protein | STAT activation | JAK-STAT signaling pathway | STAT3 pathway | STAT3 cancer | STAT3 inhibition | STAT3 activation | STAT phosphorylation | STAT3 protein | STAT1 inhibition | STAT1 pathway | STAT1 activation | STAT1 protein | JAK-STAT mechanism | STAT3 inhibitors in clinical trials | STAT3 inhibitor in vivo | STAT inhibitor review
Contact Us