STAT

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STAT Inhibitors (4)

water-soluble

Cat.No. Product Name Information Product Citations Customer Reviews
S7024 Stattic Stattic, the first nonpeptidic small molecule, potently inhibits STAT3 activation and nuclear translocation with IC50 of 5.1 μM, highly selectivity over STAT1.
S1155 S3I-201 S3I-201 shows potent inhibition of STAT3 DNA-binding activity with IC50 of 86 μM, and low activity towards STAT1 and STAT5.
  • Cancer Discov, 2012, 3(2):158-67
  • Int J Cancer, 2012, 131(12):2774-84
  • Carcinogenesis, 2013, 34(9):1994-9
S1491 Fludarabine Fludarabine is a STAT1 activation inhibitor and a DNA synthesis inhibitor.
  • J Biol Chem, 2014, 289(14):9952-60
S3030 Niclosamide Niclosamide can inhibit DNA replication and inhibit STAT with IC50 of 0.7 μM.
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