Home Immunology & Inflammation NOS inhibitor - TNF-alpha inhibitor - Interleukins inhibitor - JNK inhibitor - ERK inhibitor - STAT inhibitor Falcarindiol For research use only.

Falcarindiol

Synonyms: FAD, (3R,8S)-Falcarindiol, FaDOH

Falcarindiol (FAD, (3R,8S)-Falcarindiol, FaDOH) is a natural polyacetylene compound found rich in many plants of the Umbelliferae family. Falcarindiol suppresses LPS-stimulated expression of inducible nitric oxide synthase (iNOS), tumor necrosis factor alpha (TNFα), interleukin-6 (IL-6), and interleukin-1 beta (IL-1β). Falcarindiol attenuates the LPS-induced activation of JNK, ERK, STAT1, and STAT3 signaling molecules.

Falcarindiol Chemical Structure

Falcarindiol Chemical Structure

CAS: 225110-25-8

Selleck's Falcarindiol has been cited by 2 publications

Purity & Quality Control

Batch: Purity: 99.93%
99.93

Falcarindiol Related Products

Choose Selective NOS Inhibitors

Biological Activity

Description Falcarindiol (FAD, (3R,8S)-Falcarindiol, FaDOH) is a natural polyacetylene compound found rich in many plants of the Umbelliferae family. Falcarindiol suppresses LPS-stimulated expression of inducible nitric oxide synthase (iNOS), tumor necrosis factor alpha (TNFα), interleukin-6 (IL-6), and interleukin-1 beta (IL-1β). Falcarindiol attenuates the LPS-induced activation of JNK, ERK, STAT1, and STAT3 signaling molecules.
Targets
iNOS [1] TNFα [1] IL-6 [1] IL-1β [1] JNK [1] Click to View More Targets
NCT Number Recruitment Conditions Sponsor/Collaborators Start Date Phases
NCT06159894 Not yet recruiting
HIV Infections
Instituto de Investigación Sanitaria de la Fundación Jiménez Díaz
 December 2023 Not Applicable
NCT06116747 Enrolling by invitation
Preterm|Father-Child Relations
Hvidovre University Hospital|Odense University Hospital|Rigshospitalet Denmark|Holbaek Sygehus|Slagelse Hospital|Zealand University Hospital|Gødstrup Hospital|Aarhus University Hospital|Aalborg University Hospital|University College Absalon|Lovisenberg Diakonale Hospital
 October 31 2023 Not Applicable
NCT05391113 Recruiting
Autism Spectrum Disorder
University Hospital Tours|INSERM UMR-1253 Tours France
 July 27 2023 Not Applicable
NCT05433415 Recruiting
Adolescent Obesity|Diabetes Mellitus
Rush University Medical Center|National Institutes of Health (NIH)|University of Illinois at Chicago|National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
 March 6 2023 Not Applicable
NCT05588180 Completed
Mechanically Ventilated Patients
Fayoum University Hospital
 October 18 2022 Not Applicable

Chemical Information & Solubility

Molecular Weight 260.37 Formula

C17H24O2
CAS No. 225110-25-8 SDF --
Smiles CCCCCCCC=CC(C#CC#CC(C=C)O)O
Storage (From the date of receipt) 2 years -20°C liquid

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Tech Support

Answers to questions you may have can be found in the inhibitor handling instructions. Topics include how to prepare stock solutions, how to store inhibitors, and issues that need special attention for cell-based assays and animal experiments.

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