Glucocorticoid Receptor Agonists

Cat.No.	Product Name	Information	Product Use Citations
S1696	Hydrocortisone (Cortisol)	Hydrocortisone is a steroid hormone or glucocorticoid produced by the adrenal gland.	Bone Res, 2025, 13(1):37 Clin Cancer Res, 2025, 10.1158/1078-0432.CCR-24-1812 Cell Death Discov, 2025, 11(1):286
S1737	Prednisolone	Prednisolone is a synthetic glucocorticoid with anti-inflammatory and immunomodulating properties. This compound is widely used in the treatment of various inflammatory and autoimmune conditions. It works by suppressing the immune response and reducing inflammation in the body. The efficacy of this medication has been well-documented in clinical studies. Patients prescribed this drug should follow their healthcare provider's instructions carefully to minimize potential side effects.	International Journal of Molecular Sciences, November 30, 2019, 6036 eLife, November 19, 2019, e50036 OncoImmunology, March 12, 2026, 2643494
S5956	Dexamethasone phosphate disodium	Dexamethasone phosphate disodium is a glucocorticoid receptor agonist with both anti-inflammatory and anti-oxidative effects.	Heliyon, February 26, 2023, e14006 Cell Rep Med, 2025, S2666-3791(25)00102-8 Cell Rep, 2023, 42(6):112566
S2559	Cortisone acetate	Cortisone acetate (Cortone, NSC 49420) is an acetate salt form of cortisone that is a steroid hormone and a glucocorticoid.	Cancer Immunology, Immunotherapy, 2025, 316 Cancer Immunol Immunother, 2025, 74(10):316 iScience, 2024, 27(10):110862
S4646	Ciclesonide	Ciclesonide (Alvesco, Omnaris, RPR251526, Zetonna) is a glucocorticoid used to treat obstructive airway diseases.	Proceedings of the National Academy of Sciences, November 2025, 122(48) American Journal of Physiology-Lung Cellular and Molecular Physiology, May 1, 2023, L722-L736 American Journal of Physiology-Lung Cellular and Molecular Physiology, May 1, 2023, L722-L736
S1622	Prednisone	Prednisone is a synthetic corticosteroid agent that is particularly effective as an immunosuppressant compound.	Communications Medicine, October 9, 2025, 420 Charles University Theses, February 2, 2022, nan Bangladesh Journal of Pharmacology, December 13, 2024, 73-80
S1286	Budesonide	Budesonide(Labazenit) is a glucocorticoid steroid for the treatment of asthma, non-infectious rhinitis.	Frontiers in Immunology, May 17, 2022, 882277 Arch Toxicol, 2025, 99(3):1105-1116 bioRxiv, 2025, 2025.03.31.646052
S4752	Corticosterone	Corticosterone, the major stress hormone, is an adrenocortical steroid that has modest but significant activities as a mineralocorticoid and a glucocorticoid.	Analytical Chemistry, January 12, 2024, 1547-1555 Brain Res Bull, 2025, 225:111346 Gen Psychiatr, 2024, 37(1):e101291
S1628	Triamcinolone Acetonide	Triamcinolone acetonide is a synthetic glucocorticoid, used in the symptomatic treatment of inflammation. This compound is a synthetic glucocorticoid, used in the symptomatic treatment of inflammation.	Arch Toxicol, 2025, 99(3):1105-1116 FASEB J, 2025, 39(1):e70298 The FASEB Journal, 2025, e70298
S1992	Fluticasone propionate	Fluticasone Propionate (CCI-187881) is a synthetic glucocorticoid, used to treat non-allergic and allergic rhinitis.	Heliyon, 2024 Oct 18, e39475 Heliyon, 2024, e39475 Heliyon, 2024, 10(20):e39475
S1733	Methylprednisolone	Methylprednisolone is a synthetic glucocorticoid receptor agonist, used to achieve prompt suppression of inflammation. This compound activates ACE2 and reduces IL-6 levels, thus improves severe or critical COVID-19. It markedly reduces autophagy and apoptosis.	iScience, 2025, 114293 Food Chem Toxicol, 2024, 188:114665 Clinical Cancer Research, 2022, 4444-4455
S2570	Prednisolone Acetate	Prednisolone Acetate (Omnipred,Prednisolone-21-acetate) is a synthetic corticosteroid drug that is particularly effective as an immunosuppressant agent.	Oncogene, 2024, 43(4):235-247 J Immunotoxicol, 2021, 18(1):154-162 Eur J Rheumatol, 2021, 10.5152/eurjrheum.2021.20054
S2584	Clobetasol propionate	Clobetasol propionate (CGP9555, CCl 4725) is an anti-inflammatory corticosteroid used to treat various skin disorders.	Nat Commun, 2025, 16(1):699 Pharmacol Res, 2025, S1043-6618(25)00049-0 International Journal of Pharmaceutics, 2022 Apr 5, 121610
S1500	Betamethasone	Betamethasone (NSC-39470, SCH-4831) is a glucocorticoid steroid with anti-inflammatory and immunosuppressive properties.	Communications Medicine, October 2025, 5(1) bioRxiv, July 13, 2023, 2023.07.12.548707 BMC Pharmacol Toxicol, 2024, 25(1):25
S1701	Desonide	Desonide is a low potency topical corticosteroid.	Nat Commun, 2022, 13(1):4109 Drug Test Anal, 2020, 10.1002/dta.2917 PhD Thesis, Queen Mary University of London, 2018, 140
S1933	Triamcinolone	Triamcinolone is a glucocorticoid given, as the free alcohol or in esterified form, orally, intramuscularly, by local injection, by inhalation, or applied topically in the management of various disorders in which corticosteroids are indicated.	bioRxiv, 2025, 2025.08.03.668359 Gastroenterology, 2024, S0016-5085(24)00062-3 Drug Test Anal, 2020, 10.1002/dta.2917
S5685	Desoximetasone	Desoximetasone (Desoxymethasone, Desoximetasonum) is a synthetic glucocorticoid receptor agonist with metabolic, anti-inflammatory and immunosuppressive activity.	Free Radical Biology and Medicine, 2023, 1-10 Free Radic Biol Med, 2023, 203:1-10 Cell Death Dis, 2022, 13(6):521
S5489	Prednisone acetate	Prednisone acetate (Betapar, Cortan, Deltasone, Fernisone, Meticorten, Prednisone 21-acetate) is a glucocorticoid steroid that can be used as a glucocorticoid receptor agonist with anti-inflammatory and immunomodulating properties.	Blood Cancer J, 2022, 12(3):36 Front Immunol, 2021, 12:739605 J Immunotoxicol, 2021, 18(1):154-162
S1987	Mometasone furoate	Mometasone Furoate (SCH-32088,mometasone 17-furoate) is a glucocorticoid receptor agonist, used topically to reduce inflammation of the skin or in the airways.	Sci Rep, 2024, 14(1):30786 J Bone Oncol, 2024, 47:100618
S1888	Deflazacort	Deflazacort (MDL 458) is a glucocorticoid used as an anti-inflammatory and immunosuppressant.	Communications Medicine, 2025, 420 Drug Test Anal, 2020, 10.1002/dta.2917
S4088	Flumethasone	Flumethasone (RS-2177, NSC-54702, Flumetasone) is a glucocorticoid receptor agonist, this complex binds to the nucleus causing a variety of genetic activation and repressions.	eLife, May 16 2023, e82249 Elife, 2023, 12e82249 Drug Test Anal, 2020, 10.1002/dta.2917
S5184	Dexamethasone palmitate	Dexamethasone palmitate (DXP), a lipophilic prodrug of Dexamethasone (DXM), is a glucocorticoid receptor agonist with a 47-fold lower affinity for the glucocorticoid receptor than DXM. This compound exhibits anti-inflammatory activity.	Dis Model Mech, 2022, dmm.049109 Hematology, 2022, 27(1):32-42
S1669	Loteprednol etabonate	Loteprednol etabonate is a potent glucocorticoid receptor agonist, used in treatment of inflammation of the eye due to allergies.	Int J Biol Macromol, 2025, 306(Pt 3):141644
S2470	Fluocinolone Acetonide	Fluocinolone Acetonide (Flucort-N) is a corticosteroid that binds to the cytosolic glucocorticoid receptor.	Acta Pharmaceutica Sinica B, 2023, 662-677 Acta Pharm Sin B, 2023, 13(2):662-677
S1688	Betamethasone Dipropionate	Betamethasone Dipropionate (SCH 11460) is a glucocorticoid steroid with anti-inflammatory and immunosuppressive abilities.	Journal of Nanobiotechnology, 2024, 706 J Nanobiotechnology, 2024, 22(1):706
S5973	Methylprednisolone Acetate	Methylprednisolone (NSC-19987, Medrol) acetate is a synthetic glucocorticoid receptor agonist, used to achieve prompt suppression of inflammation. Methylprednisolone activates ACE2 and reduces IL-6 levels, thus improves severe or critical COVID-19. Methylprednisolone markedly reduces autophagy and apoptosis.	Current Issues in Molecular Biology, 2022, 1046-1061
S5486	Fluorometholone	Fluorometholone (Oxylone) is a synthetic glucocorticoid with anti-inflammatory and anti-allergic properties. It is usually used as eye drops in the treatment of allergic and inflammatory conditions of the eye.	Drug Test Anal, 2020, 10.1002/dta.2917
S1689	Meprednisone	Meprednisone (NSC 527579, SCH 4358) is a glucocorticoid and a methylated derivative of prednisone.
S1690	Betamethasone Valerate	Betamethasone Valerate is a moderately potent glucocorticoid steroid with anti-inflammatory and immunosuppressive properties.
S2608	Fluocinonide	Fluocinonide (Vanos,nsc 101791) is a potent glucocorticoid steroid used topically as anti-inflammatory agent for the treatment of skin disorders such as eczema.
S3078	Beclomethasone dipropionate	Beclomethasone dipropionate(Beclovent,Beconase,Vancenase) is a potent glucocorticoid steroid used for the treatment of rhinitis and sinusitis.
S3617	(20S)-Protopanaxatriol	(20S)-Protopanaxatriol (g-PPT, 20(S)-APPT), a neuroprotective metabolite of ginsenoside, protopanaxatriol (g-PPT), is a functional ligand for both GR and ERbeta and could modulate endothelial cell functions through the glucocorticoid receptor (GR) and estrogen receptor (ER).
S4228	Fluorometholone Acetate	Fluorometholone Acetate (NSC 47438,Oxylone acetate) is a synthetic corticosteroid, used in the treatment of steroid responsive inflammatory conditions of the eye.
E4918	BecloMethasone	Beclomethasone(Beclometasone) is a prototype agonist of glucocorticoid receptor. Beclomethasone and its derivatives display have higher binding affinity to glucocorticoid receptors in rat liver, thymus, and hypophysis.
S4775	Cortodoxone	Cortodoxone (11-Deoxycortisol, cortexolone, 11-Desoxycortisol, 17α,21-dihydroxyprogesterone), also known as 11-Deoxycortisol, is a glucocorticoid steroid hormone.
S1322	Dexamethasone	Dexamethasone is a potent synthetic member of the glucocorticoid class of steroid drugs, and an interleukin receptor modulator that has anti-inflammatory and immunosuppressant effects. Dexamethasone induces autophagy and mitophagy. Dexamethasone is tested in hospitalized patients with COVID-19 and is found to have benefits for critically ill patients.	Blood, August 15 2024, 757-770 Nat Commun, 2026, 10.1038/s41467-026-70862-w Adv Sci (Weinh), 2026, 13(22):e09980
S4028	Dexamethasone Sodium Phosphate	Dexamethasone (Dexamethasone 21-phosphate disodium salt) is a potent synthetic member of the glucocorticoid class of steroid drugs, and an interleukin receptor modulator that has anti-inflammatory and immunosuppressant effects.	Proc Natl Acad Sci U S A, 2025, 122(12):e2426107122 J Tradit Chin Med, 2025, 45(4):739-746 Cancer Cell, 2024, 42(9):1507-1527.e11