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Dexamethasone phosphate disodium

Name: Dexamethasone phosphate disodium
Brand: Selleck Chemicals
SKU: S5956
Rating: 5 (16 reviews)

Synonyms: DEX, Dexamethasone 21-phosphate disodium salt

Catalog No.S5956 Purity: 99.98%

Dexamethasone phosphate disodium is a glucocorticoid receptor agonist with both anti-inflammatory and anti-oxidative effects.

Dexamethasone phosphate disodium Chemical Structure

CAS: 2392-39-4

Selleck's Dexamethasone phosphate disodium has been cited by 16 publications

Purity & Quality Control

Batch: S595601 Water] 100 mg/mL] false] DMSO] Insoluble] false] Ethanol] Insoluble] false Purity: 99.98%

99.98

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Choose Selective Glucocorticoid Receptor Inhibitors

Biological Activity

Description

Dexamethasone phosphate disodium is a glucocorticoid receptor agonist with both anti-inflammatory and anti-oxidative effects.

Targets

glucocorticoid receptor ^[1]

NCT Number	Recruitment	Conditions	Sponsor/Collaborators	Start Date	Phases
Clinical Trial Information (data from https://clinicaltrials.gov, updated on 2024-01-11)
NCT06142682	Not yet recruiting	Cochlear Implant	MED-EL Elektromedizinische Geräte GesmbH	January 1 2024	Not Applicable
NCT05935293	Not yet recruiting	Renal Transplantation\|Dexmedetomidine	Eduardo Schiffer\|University Hospital Geneva	December 1 2023	Phase 4
NCT06133712	Recruiting	Carpal Tunnel\|Dexmedetomidine\|Ozone\|Dexamethasone	Tanta University	November 1 2023	Not Applicable
NCT05978622	Recruiting	Diabetic Macular Edema	AbbVie	October 30 2023	--
NCT06016465	Recruiting	Migraine	Texas Tech University Health Sciences Center El Paso	September 15 2023	Early Phase 1

References

Chemical Information & Solubility

Molecular Weight	516.4	Formula	C₂₂H₂₈FNa₂O₈P
CAS No.	2392-39-4	SDF	--
Smiles	[Na+].[Na+].CC1CC2C3CCC4=CC(=O)C=CC4(C)C3(F)C(O)CC2(C)C1(O)C(=O)CO[P]([O-])([O-])=O
Storage (From the date of receipt)	3 years -20°C powder	Storage of Stock Solutions Aliquot the stock solutions to avoid repeated freeze-thaw cycles	1 year-80°Cin solvent
Storage (From the date of receipt)	3 years -20°C powder		1 month-20°Cin solvent

In vitro
Batch:

Water : 100 mg/mL

DMSO : Insoluble ( Moisture-absorbing DMSO reduces solubility. Please use fresh DMSO.)

Ethanol : Insoluble

Molecular Weight Calculator

In vivo
Batch:

Add solvents to the product individually and in order.

In vivo Formulation Calculator

Preparing Stock Solutions

Molarity Calculator

Dilution Calculator Molecular Weight Calculator

In vivo Formulation Calculator (Clear solution)

Step 1: Enter information below (Recommended: An additional animal making an allowance for loss during the experiment)

Dosage: mg/kg Average weight of animals: g Dosing volume per animal:μL Number of animals:

Step 2: Enter the in vivo formulation (This is only the calculator, not formulation. Please contact us first if there is no in vivo formulation at the solubility Section.)

% DMSO + % + % Tween 80 + % ddH₂O

%DMSO+ %

Calculation results:

Working concentration: mg/ml;

Method for preparing DMSO master liquid: mg drug pre-dissolved in μL DMSO ( Master liquid concentration mg/mL, Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug. )

Method for preparing in vivo formulation: Take μL DMSO master liquid, next addμL PEG300, mix and clarify, next addμL Tween 80, mix and clarify, next add μL ddH₂O, mix and clarify.

Method for preparing in vivo formulation: Take μL DMSO master liquid, next add μL Corn oil, mix and clarify.

Note: 1. Please make sure the liquid is clear before adding the next solvent.
2. Be sure to add the solvent(s) in order. You must ensure that the solution obtained, in the previous addition, is a clear solution before proceeding to add the next solvent. Physical methods such
as vortex, ultrasound or hot water bath can be used to aid dissolving.

Tech Support

Answers to questions you may have can be found in the inhibitor handling instructions. Topics include how to prepare stock solutions, how to store inhibitors, and issues that need special attention for cell-based assays and animal experiments.

Handling Instructions

Tel: +1-832-582-8158 Ext:3
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