Dexamethasone phosphate disodium

Catalog No.S5956 Synonyms: DEX, Dexacort, Decadron, Dexair, Hexadrol, Maxidex, Dexamethasone 21-phosphate disodium salt

For research use only.

Dexamethasone phosphate disodium (DEX, Dexacort, Decadron, Dexair, Hexadrol, Maxidex) is a glucocorticoid receptor agonist with both anti-inflammatory and anti-oxidative effects.

Dexamethasone phosphate disodium Chemical Structure

CAS No. 2392-39-4

Selleck's Dexamethasone phosphate disodium has been cited by 12 Publications

Purity & Quality Control

Choose Selective Glucocorticoid Receptor Inhibitors

Biological Activity

Description Dexamethasone phosphate disodium (DEX, Dexacort, Decadron, Dexair, Hexadrol, Maxidex) is a glucocorticoid receptor agonist with both anti-inflammatory and anti-oxidative effects.
Targets
glucocorticoid receptor [1]

Protocol (from reference)

Solubility (25°C)

In vitro

Chemical Information

Molecular Weight 516.4
Formula

C22H28FNa2O8P

CAS No. 2392-39-4
Storage 3 years -20°C powder
2 years -80°C in solvent

In vivo Formulation Calculator (Clear solution)

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Method for preparing DMSO master liquid: mg drug pre-dissolved in μL DMSO ( Master liquid concentration mg/mL, Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug. )

Method for preparing in vivo formulation: Take μL DMSO master liquid, next addμL PEG300, mix and clarify, next addμL Tween 80, mix and clarify, next add μL ddH2O, mix and clarify.

Method for preparing in vivo formulation: Take μL DMSO master liquid, next add μL Corn oil, mix and clarify.

Note: 1. Please make sure the liquid is clear before adding the next solvent.
2. Be sure to add the solvent(s) in order. You must ensure that the solution obtained, in the previous addition, is a clear solution before proceeding to add the next solvent. Physical methods such
as vortex, ultrasound or hot water bath can be used to aid dissolving.

Molarity Calculator

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Clinical Trial Information

NCT Number Recruitment Interventions Conditions Sponsor/Collaborators Start Date Phases
NCT05340725 Not yet recruiting Drug: DEX-IV|Drug: DEX-Rectal|Drug: DEX-Nano-Rectal Postoperative Pain Assiut University May 1 2022 Phase 2|Phase 3
NCT05376761 Recruiting Drug: Dexmedetomidine PD - Parkinson''s Disease Beijing Tiantan Hospital May 31 2022 Phase 4
NCT05441943 Recruiting Procedure: Lymphovenous anastomosis Breast Cancer Lymphedema|Secondary Lymphedema|Iatrogenic Lymphedema|Lymphedema|Lymphedema of Upper Limb|Lymphedema Arm|Lymphedema Breast Cancer|Breast Neoplasm|Neoplasms|Breast Cancer|Breast Diseases|Lymphatic Diseases|Skin Diseases|Postoperative Complications|Pathologic Processes|Anastomose|Surgery|Surgical; Lymphedema Postmastectomy|Postmastectomy Lymphedema|Postmastectomy Lymphedema Syndrome Left Upper Limb|Postmastectomy Lymphedema Syndrome Right Upper Limb|Postmastectomy Lymphedema Syndrome Odense University Hospital|Danish Cancer Society May 11 2022 Not Applicable
NCT05300802 Recruiting Drug: Placebo|Drug: Dexmedetomidine Hcl 100 Mcg/mL Inj Congenital Heart Disease in Children|Cardiopulmonary Bypass National Cardiovascular Center Harapan Kita Hospital Indonesia December 16 2021 Phase 2|Phase 3

(data from https://clinicaltrials.gov, updated on 2022-08-01)

Tech Support

Answers to questions you may have can be found in the inhibitor handling instructions. Topics include how to prepare stock solutions, how to store inhibitors, and issues that need special attention for cell-based assays and animal experiments.

Handling Instructions

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