|
S1150
|
Paclitaxel (Taxol) |
Paclitaxel (Taxol, Onxol, Nov-Onxol) is a microtubule polymer stabilizer with IC50 of 0.1 pM in human endothelial cells. |
|
|
|
S1148
|
Docetaxel (Taxotere) |
Docetaxel, an analog of taxol, is an inhibitor of depolymerisation of microtubules through binding to stabilized microtubules. |
|
|
|
S1241
|
Vincristine |
Vincristine is an inhibitor of polymerization of microtubules by binding to tubulin with IC50 of 32 μM. |
|
|
|
S1364
|
Epothilone B (EPO906) |
Epothilone B is a Taxol-like microtubule-stabilizing agent with EC0.01 of 1.8 μM. |
|
|
|
S2775
|
Nocodazole |
Nocodazole inhibits Abl, Abl(E255K) and Abl(T315I) with IC50 of 0.21 μM, 0.53 μM and 0.64 μM, respectively. |
|
|
|
S4071
|
Griseofulvin |
Griseofulvin, a production from some strains of the mold Penicillium griseofulvumam, is able to inhibit cell mitosis by interfering with microtubule function. |
|
|
|
S1165
|
ABT-751 |
ABT-751 (E7010) binds to the colchicine site on β-tubulin and inhibits polymerization of microtubules. |
|
|
|
S1297
|
Epothilone A |
Epothilone A is a Taxol-like microtubule-stabilizing agent with EC0.01 of 2 μM. |
|
|
|
S2209
|
Vinflunine Tartrate |
Vinflunine is a new vinca alkaloid uniquely fluorinated with the properties of mitotic-arresting and tubulin-interacting activity. |
|
|
|
S2195
|
CYT997 |
CYT997 is a potent tubulin polymerization inhibitor with IC50 of ~3 μM. |
|
|
