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Microtubule
| Cat.No. | Product Name | Feedback | Added |
|---|---|---|---|
| S1165 | ABT-751 | Mar 2010 | |
| ABT-751 is a novel bioavailable tubulin-binding and antimitotic sulfonamide agent with IC50 of about 1.5 and 3.4 µM in neuroblastoma and non-neuroblastoma cell lines, respectively. | |||
| S2195 | CYT997 | Feb 2011 | |
| CYT997, a small molecule inhibits the polymerization of tubulin with an IC50 of 3 μmol/L and shows an IC50 of between 1 and 100 nmol/L across a panel of cancer cell lines. | |||
| S1148 | Docetaxel (Taxotere) | Feb 2010 | |
| Docetaxel (Taxotere) is an microtubule disassembly inhibitor with IC50 of a range of 0.31–100 ηM. | |||
| S1297 | Epothilone A | Jun 2010 | |
| Epothilone A is a new kind of microtubule function inhibitor with an IC50 of 4.4 nM for tubulin polymerization and cytotoxicity. | |||
| S1364 | Epothilone B | Jun 2010 | |
| Epothilone B is a new kind of cancer agents and microtubule function inhibitor with an IC50 of 3.5 nM. | |||
| S1150 | Paclitaxel (Taxol) | Feb 2010 | |
| Paclitaxel also known as Taxol, Onxol, Nov-Onxol is a microtubule polymer stabilizer with an IC50 of 0.1 pM for human endothelial cells. | |||
| S1241 | Vincristine Sulfate | May 2010 | |
| Vincristine Sulfate is a microtubule function inhibitor with IC50 of 10.4±1.1, 28.1±3.4, 22.4±2.1 µM for HL-60, Bel7402, HO-8910, respectively. | |||
| S2209 | Vinflunine Tartrate | Mar 2011 | |
| Vinflunine Tartrate is a tartrate salt of vinflunine that is a new microtubule inhibitor agent with IC50 of 18.8 nM. | |||
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Customer's Feedback
| Dongfeng Chen, The Rausing Lab |
| "Your product U0126(Cat.NO S1102) works well in our experiments. I hope I can get more excellent products from your company in future." |
| R.B. Cambridge |
| "I have used the chemical that I bought from you(Selleck,PTC-124) and it worked well.So we will eventually be ordering more." |
| Zhenghe John Wang Assistant Professor, Case Western Reserve University |
| "We have purchased LBH-589, Saha and MS-275 from you and they all worked well." |
| Jenny Sun |
| "We used the LBH-589 in our experiments. The compound is easy to use with excellent reproducibility." |
| Yu Wang, Harvard University |
| "The GDC0449 compound worked very well. The results in my hands are equally good as what's been published. Thanks for this great resource for our research." |
| Dung-Fang Lee |
| "Based on our preliminary data, I found MLN8237 and VX-680 have good effects in inhibiting Aurka-maintaining ESC self-renewal in mouse ES cells." |
Latest Catalog
| May 2010 Selleck Latest Catalog | ![]() |

