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Histamine Receptor

Compare Histamine Receptor Antagonists

Cat.No.	Product Name	Solubility (25°C)
S1801	Ranitidine (Zantac)	70 mg/mL	70 mg/mL	<1 mg/mL
S1847	Clemastine Fumarate	<1 mg/mL	35 mg/mL	3 mg/mL
S3163	Benztropine mesylate	81 mg/mL	50 mg/mL	81 mg/mL
S1291	Cetirizine DiHCl	92 mg/mL	92 mg/mL	<1 mg/mL
S1357	Lidocaine(Alphacaine)	9 mg/mL	47 mg/mL	47 mg/mL
S4026	Hydroxyzine 2HCl	560 mg/mL	<1 mg/mL	<1 mg/mL
S4012	Desloratadine	<1 mg/mL	26 mg/mL	62 mg/mL
S4008	Pemirolast (BMY 26517) potassium	53 mg/mL	<1 mg/mL	<1 mg/mL
S1245	Dimebon (Latrepirdine)	79 mg/mL	24 mg/mL	13 mg/mL
S1358	Loratadine	<1 mg/mL	17 mg/mL	77 mg/mL
S1382	Mianserin HCl	30 mg/mL	60 mg/mL	21 mg/mL
S1890	Nizatidine	28 mg/mL	66 mg/mL	18 mg/mL
S1845	Cimetidine(Tagamet)	<1 mg/mL	51 mg/mL	3 mg/mL
S1816	Chlorpheniramine Maleate	78 mg/mL	78 mg/mL	78 mg/mL
S2494	Olopatadine HCl (Opatanol)	13 mg/mL	75 mg/mL	8 mg/mL
S2552	Azelastine HCl (Astelin)	35 mg/mL	84 mg/mL	84 mg/mL
S2024	Ketotifen fumarate (Zaditor)	<1 mg/mL	8 mg/mL	<1 mg/mL
S2044	Cyproheptadine HCl (Periactin)	<1 mg/mL	65 mg/mL	20 mg/mL
S2065	Lafutidine	<1 mg/mL	86 mg/mL	13 mg/mL
S2078	Famotidine (Pepcid)	<1 mg/mL	67 mg/mL	<1 mg/mL
S2107	Mizolastine (Mizollen)	<1 mg/mL	<1 mg/mL	<1 mg/mL
S1880	Roxatidine acetate HCl	77 mg/mL	77 mg/mL	12 mg/mL
S2813	Ciproxifan	1 mg/mL	54 mg/mL	54 mg/mL
S3146	Tripelennamine HCl	58 mg/mL	2 mg/mL	1 mg/mL
S3176	Betahistine 2HCl	38 mg/mL	38 mg/mL	1 mg/mL
S3186	Azatadine dimaleate	105 mg/mL	105 mg/mL	<1 mg/mL
S3208	Fexofenadine HCl	2 mg/mL	107 mg/mL	107 mg/mL
S3037	Bepotastine Besilate	<1 mg/mL	109 mg/mL	<1 mg/mL
S3052	Rupatadine Fumarate	<1 mg/mL	9 mg/mL	13 mg/mL
S2905	JNJ-7777120	<1 mg/mL	56 mg/mL	8 mg/mL

Histamine Receptor Antagonists (31)
water-soluble

Cat.No.	Product Name	Information
S1801	Ranitidine (Zantac)	Ranitidine (Zantac) is a histamine H2-receptor antagonist with IC50 of 3.3 ± 1.4 μM.
S1847	Clemastine Fumarate	Clemastine Fumarate (Clemastine) is a selective histamine H1 receptor antagonist with IC50 of 3 nM.
S3163	Benztropine mesylate	Benztropine is a dopamine transporter (DAT) inhibitor with IC50 of 118 nM.
S1291	Cetirizine DiHCl	Cetirizine Dihydrochloride is an antihistamine.
S1357	Lidocaine(Alphacaine)	Lidocaine (Alphacaine) is a selective inverse peripheral histamine H1-receptor agonist with an IC50 of >32 μM.
S4026	Hydroxyzine 2HCl	Hydroxyzine is a histamine H1-receptor antagonist, inhibits binding of [³H]pyrilamine/[³H]desloratadine to human histamine H1 receptor with IC50 of 10 nM/19 nM.
S4012	Desloratadine	Desloratadine is a potent antagonist for human histamine H1 receptor with IC50 of 51 nM.
S4008	Pemirolast (BMY 26517) potassium	Pemirolast potassium (BMY 26517) is a histamine H1 antagonist and mast cell stabilizer that acts as an antiallergic agent.
S1245	Dimebon (Latrepirdine)	Dimebon is an antihistamine drug.
S1358	Loratadine	Loratadine is a selective inverse peripheral histamine H1-receptor agonist with an IC50 of >32 μM.

Cat.No.	Product Name	Information
S1382	Mianserin HCl	Mianserin is a psychoactive agent of the tetracyclic antidepressant.
S1890	Nizatidine	Nizatidine is a histamine H2-receptor antagonist with and IC50 of 6.7 nM for AChE.
S1845	Cimetidine(Tagamet)	Cimetidine(Tagamet), a histamine congener, competitively inhibits histamine binding to histamine H2 receptors.
S1816	Chlorpheniramine Maleate	Chlorpheniramine (Chlorpheniramine maleate, Chlorphenamine) is an histamine H1 receptor antagonist with IC50 of 12 nM.
S2494	Olopatadine HCl (Opatanol)	Olopatadine hydrochloride(Opatanol) is a histamine blocker and mast cell stabilizer with an IC50 of 559 μM for the release of histamine
S2552	Azelastine HCl (Astelin)	Azelastine hydrochloride (Astelin) is a potent, second-generation, selective, histamine antagonist.
S2585	Brompheniramine	Brompheniramine is a histamine H1 receptors antagonist.
S2024	Ketotifen fumarate (Zaditor)	Ketotifen fumarate (Zaditor) is a fumaric acid salt of ketotifen which is a H1-antihistamine and mast cell stabilizer.
S2044	Cyproheptadine HCl (Periactin)	Cyproheptadine hydrochloride (Periactin) is a hydrochloride salt form of cyproheptadine which is a histamine receptor antagonist for 5-HT₂ receptor with IC50 of 0.6 nM.
S2065	Lafutidine	Lafutidine, a newly developed histamine H(2)-receptor antagonist, inhibits gastric acid secretion.

Cat.No.	Product Name	Information
S2078	Famotidine (Pepcid)	Famotidine is a histamine H2–receptor antagonist with IC50 of 0.6 mM, commonly used to treat heartburn, GERD, ulcers, and other digestive conditions.
S2107	Mizolastine (Mizollen)	Mizolastine is a histamine H1-receptor antagonist with IC50 of 47 nM used in the treatment of hay fever (seasonal allergic rhinitis), hives and other allergic reactions.
S1880	Roxatidine acetate HCl
S2813	Ciproxifan	Ciproxifan is a highly potent and selective H3-receptor antagonist with IC50 of 9.2 nM.
S3146	Tripelennamine HCl	Tripelennamine is a widely used H1 antagonist, inhibiting PhIP glucuronidation with IC50 of 30 μM.
S3176	Betahistine 2HCl	Betahistine is a histamine H3 receptors inhibitor with IC50 of 1.9 μM.
S3186	Azatadine dimaleate	Azatadine is an histamine and cholinergic inhibitor with IC50 of 6.5 nM and 10 nM, respectively.
S3208	Fexofenadine HCl	Fexofenadine inhibits histamine H1 receptor with IC50 of 246 nM.
S3037	Bepotastine Besilate	Bepotastine is a non-sedating, selective antagonist of histamine 1 (H1) receptor with pIC50 of 5.7.
S3052	Rupatadine Fumarate	Rupatadine is an inhibitor of PAFR and histamine (H1) receptor with K_i of 550 and 102 nM, respectively.

Cat.No.	Product Name	Information	Product Citations	Customer Reviews
S2905	JNJ-7777120	JNJ-7777120 is a potent and selective non-imidazole histamine H4 receptor antagonist with K_i of 4.5 nM.

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Histamine Receptor

Compare Histamine Receptor Inhibitors

Histamine Receptor Antagonists (31)
water-soluble

Cat.No.	Product Name	Solubility (25°C)
Cat.No.	Product Name	Water	DMSO	Ethanol
S1801	Ranitidine (Zantac)	70 mg/mL	70 mg/mL	<1 mg/mL
S1847	Clemastine Fumarate	<1 mg/mL	35 mg/mL	3 mg/mL
S3163	Benztropine mesylate	81 mg/mL	50 mg/mL	81 mg/mL
S1291	Cetirizine DiHCl	92 mg/mL	92 mg/mL	<1 mg/mL
S1357	Lidocaine(Alphacaine)	9 mg/mL	47 mg/mL	47 mg/mL
S4026	Hydroxyzine 2HCl	560 mg/mL	<1 mg/mL	<1 mg/mL
S4012	Desloratadine	<1 mg/mL	26 mg/mL	62 mg/mL
S4008	Pemirolast (BMY 26517) potassium	53 mg/mL	<1 mg/mL	<1 mg/mL
S1245	Dimebon (Latrepirdine)	79 mg/mL	24 mg/mL	13 mg/mL
S1358	Loratadine	<1 mg/mL	17 mg/mL	77 mg/mL
S1382	Mianserin HCl	30 mg/mL	60 mg/mL	21 mg/mL
S1890	Nizatidine	28 mg/mL	66 mg/mL	18 mg/mL
S1845	Cimetidine(Tagamet)	<1 mg/mL	51 mg/mL	3 mg/mL
S1816	Chlorpheniramine Maleate	78 mg/mL	78 mg/mL	78 mg/mL
S2494	Olopatadine HCl (Opatanol)	13 mg/mL	75 mg/mL	8 mg/mL
S2552	Azelastine HCl (Astelin)	35 mg/mL	84 mg/mL	84 mg/mL
S2024	Ketotifen fumarate (Zaditor)	<1 mg/mL	8 mg/mL	<1 mg/mL
S2044	Cyproheptadine HCl (Periactin)	<1 mg/mL	65 mg/mL	20 mg/mL
S2065	Lafutidine	<1 mg/mL	86 mg/mL	13 mg/mL
S2078	Famotidine (Pepcid)	<1 mg/mL	67 mg/mL	<1 mg/mL
S2107	Mizolastine (Mizollen)	<1 mg/mL	<1 mg/mL	<1 mg/mL
S1880	Roxatidine acetate HCl	77 mg/mL	77 mg/mL	12 mg/mL
S2813	Ciproxifan	1 mg/mL	54 mg/mL	54 mg/mL
S3146	Tripelennamine HCl	58 mg/mL	2 mg/mL	1 mg/mL
S3176	Betahistine 2HCl	38 mg/mL	38 mg/mL	1 mg/mL
S3186	Azatadine dimaleate	105 mg/mL	105 mg/mL	<1 mg/mL
S3208	Fexofenadine HCl	2 mg/mL	107 mg/mL	107 mg/mL
S3037	Bepotastine Besilate	<1 mg/mL	109 mg/mL	<1 mg/mL
S3052	Rupatadine Fumarate	<1 mg/mL	9 mg/mL	13 mg/mL
S2905	JNJ-7777120	<1 mg/mL	56 mg/mL	8 mg/mL

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Histamine Receptor Antagonists (31)water-soluble

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Histamine Receptor Antagonists (31)
water-soluble