Mizolastine

Catalog No.S2107 Synonyms: SL 850324

Mizolastine  Chemical Structure

Molecular Weight(MW): 432.49

Mizolastine is a histamine H1-receptor antagonist with IC50 of 47 nM used in the treatment of hay fever (seasonal allergic rhinitis), hives and other allergic reactions.

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Biological Activity

Description Mizolastine is a histamine H1-receptor antagonist with IC50 of 47 nM used in the treatment of hay fever (seasonal allergic rhinitis), hives and other allergic reactions.
Targets
Histamine H1 receptor [1]
47 nM

Protocol

References

Solubility (25°C)

In vitro DMSO Insoluble
Water Insoluble
Ethanol Insoluble warmed

* Please note that Selleck tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.

Chemical Information

Molecular Weight 432.49
Formula

C24H25FN6O

CAS No. 108612-45-9
Storage powder
Synonyms SL 850324

Bio Calculators

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Calculate the mass, volume or concentration required for a solution. The Selleck molarity calculator is based on the following equation:

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Clinical Trial Information

NCT Number Recruitment Conditions Sponsor/Collaborators Start Date Phases
NCT01928316 Completed Healthy Xian-Janssen Pharmaceutical Ltd. June 2009 Phase 1

Tech Support

Answers to questions you may have can be found in the inhibitor handling instructions. Topics include how to prepare stock solutions, how to store inhibitors, and issues that need special attention for cell-based assays and animal experiments.

Handling Instructions

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Histamine Receptor Signaling Pathway Map

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Cell Lines Assay Type Concentration Incubation Time Formulation Activity Description PMID