Roxatidine Acetate HCl

Synonyms: HOE 760

Roxatidine Acetate HCl(HOE 760) is a specific and competitive histamin H2-receptor antagonist, with IC50 of 3.2 μM, inhibits gastric acid secretion and ulcer formation.

Roxatidine Acetate HCl Chemical Structure

Roxatidine Acetate HCl Chemical Structure

CAS: 93793-83-0

Purity & Quality Control

Batch: S188001 DMSO] 77 mg/mL] false] Water] 77 mg/mL] false] Ethanol] 12 mg/mL] false Purity: 99.48%
99.48

Roxatidine Acetate HCl Related Products

Choose Selective Histamine Receptor Inhibitors

Biological Activity

Description Roxatidine Acetate HCl(HOE 760) is a specific and competitive histamin H2-receptor antagonist, with IC50 of 3.2 μM, inhibits gastric acid secretion and ulcer formation.
Targets
Histamine H2 receptor [1]
3.2 μM

Chemical Information & Solubility

Molecular Weight 384.9 Formula

C19H28N2O4.HCl

CAS No. 93793-83-0 SDF Download Roxatidine Acetate HCl SDF
Smiles CC(=O)OCC(=O)NCCCOC1=CC=CC(=C1)CN2CCCCC2.Cl
Storage (From the date of receipt)

In vitro
Batch:

DMSO : 77 mg/mL ( (200.05 mM); Moisture-absorbing DMSO reduces solubility. Please use fresh DMSO.)

Water : 77 mg/mL

Ethanol : 12 mg/mL


Molecular Weight Calculator

In vivo
Batch:

Add solvents to the product individually and in order.


In vivo Formulation Calculator

Preparing Stock Solutions

Molarity Calculator

Mass Concentration Volume Molecular Weight

In vivo Formulation Calculator (Clear solution)

Step 1: Enter information below (Recommended: An additional animal making an allowance for loss during the experiment)

mg/kg g μL

Step 2: Enter the in vivo formulation (This is only the calculator, not formulation. Please contact us first if there is no in vivo formulation at the solubility Section.)

% DMSO % % Tween 80 % ddH2O
%DMSO %

Calculation results:

Working concentration: mg/ml;

Method for preparing DMSO master liquid: mg drug pre-dissolved in μL DMSO ( Master liquid concentration mg/mL, Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug. )

Method for preparing in vivo formulation: Take μL DMSO master liquid, next addμL PEG300, mix and clarify, next addμL Tween 80, mix and clarify, next add μL ddH2O, mix and clarify.

Method for preparing in vivo formulation: Take μL DMSO master liquid, next add μL Corn oil, mix and clarify.

Note: 1. Please make sure the liquid is clear before adding the next solvent.
2. Be sure to add the solvent(s) in order. You must ensure that the solution obtained, in the previous addition, is a clear solution before proceeding to add the next solvent. Physical methods such
as vortex, ultrasound or hot water bath can be used to aid dissolving.

Tech Support

Answers to questions you may have can be found in the inhibitor handling instructions. Topics include how to prepare stock solutions, how to store inhibitors, and issues that need special attention for cell-based assays and animal experiments.

Handling Instructions

Tel: +1-832-582-8158 Ext:3
If you have any other enquiries, please leave a message.

* Indicates a Required Field

Please enter your name.
Please enter your email. Please enter a valid email address.
Please write something to us.
Tags: buy Roxatidine Acetate HCl | Roxatidine Acetate HCl ic50 | Roxatidine Acetate HCl price | Roxatidine Acetate HCl cost | Roxatidine Acetate HCl solubility dmso | Roxatidine Acetate HCl purchase | Roxatidine Acetate HCl manufacturer | Roxatidine Acetate HCl research buy | Roxatidine Acetate HCl order | Roxatidine Acetate HCl mouse | Roxatidine Acetate HCl chemical structure | Roxatidine Acetate HCl mw | Roxatidine Acetate HCl molecular weight | Roxatidine Acetate HCl datasheet | Roxatidine Acetate HCl supplier | Roxatidine Acetate HCl in vitro | Roxatidine Acetate HCl cell line | Roxatidine Acetate HCl concentration | Roxatidine Acetate HCl nmr