+ Product Pathways
- All Targets
- Angiogenesis/Tyrosine Kinase
- Cell Cycle/Checkpoint
- HDAC
- Apoptosis
- PARP
- Aurora/Ksp
- MAPK
- PI3K/Akt/mTOR
- Hormone
- Integrase/CCR5
- Proteases/HSP90/HSP70
- Wnt/Hedgehog/Notch
- Jak/Stat
- Ca/cAMP/Lipid Signaling
- Neuro Signaling
- TGF-beta/Smad Signaling
- GPCR
- Ion channel
- Cytochrome P450
- Others
- Cancer
- Infection
- Endocrinology
- Metabolic Disease
- Inflammation
- Immunology
- Neurological Disease
- Cardiovascular Disease
Akt
| Cat.No. | Product Name | Feedback | Added |
|---|---|---|---|
| S2670 | A-674563 | Aug 2011 | |
| A-674563 is a potent selective protein kinase B/Akt inhibitor with an IC50 of 14 nM. | |||
| S1558 | AT7867 | Nov 2010 | |
| AT7867 is a potent and oral AKT and p70 S6 kinase inhibitor with an IC50 of 17 nM. | |||
| S2635 | CCT128930 | Jul 2011 | |
| CCT128930 is a novel potent ATP-competitive, AKT inhibitor with an IC50 of 6 nM. | |||
| S1113 | GSK690693 | Sep 2009 | |
| pan-Akt kinase inhibitor,IC50 of Akt 1, 2, and 3 at 2, 13, and 9 nM respectively. | |||
| S1078 | MK-2206 | Jun 2009 | |
| MK-2206 is a highly selective, potent non-ATP competitive allosteric Akt inhibitor with IC50 of 5.3 nM,12 nM, 65 nM for Akt1, Akt2 and Akt3 respectively. | |||
| S2238 | Palomid 529 (P529) | May 2011 | |
| Palomid 529 (P529) is a novel potent antitumour PI3K/Akt/mTOR inhibitor with a GI50 of <35 μM in the NCI-60 cell lines panel. | |||
| S1037 | Perifosine | Apr 2009 | |
| Perifosine is a novel Akt and PI3K inhibitor with IC50 of median 4.7 µM. | |||
| S1556 | PHT-427 | Nov 2010 | |
| PHT-427 is a Novel Akt/phosphatidylinositide-dependent protein kinase 1 pleckstrin homology domain inhibitor with an IC50 of 6.3 μM for AKT inhibition in Panc-1 cells. | |||
| S1117 | Triciribine | Sep 2009 | |
| Triciribine is a synthetic tricyclic nucleoside which acts as a specific inhibitor of the Akt signaling pathway. | |||
| S2732 | Triciribine phosphate (NSC-280594) | Nov 2011 | |
| Triciribine phosphate (NSC-280594) is a novel potent, small-molecule Akt inhibitor. | |||
Buy Now / Print Quote
Find Multiple Products by Catalog Number
Customer's Feedback
| Dongfeng Chen, The Rausing Lab |
| "Your product U0126(Cat.NO S1102) works well in our experiments. I hope I can get more excellent products from your company in future." |
| R.B. Cambridge |
| "I have used the chemical that I bought from you(Selleck,PTC-124) and it worked well.So we will eventually be ordering more." |
| Zhenghe John Wang Assistant Professor, Case Western Reserve University |
| "We have purchased LBH-589, Saha and MS-275 from you and they all worked well." |
| Jenny Sun |
| "We used the LBH-589 in our experiments. The compound is easy to use with excellent reproducibility." |
| Yu Wang, Harvard University |
| "The GDC0449 compound worked very well. The results in my hands are equally good as what's been published. Thanks for this great resource for our research." |
| Dung-Fang Lee |
| "Based on our preliminary data, I found MLN8237 and VX-680 have good effects in inhibiting Aurka-maintaining ESC self-renewal in mouse ES cells." |
Latest Catalog
| May 2010 Selleck Latest Catalog | ![]() |

