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Methyl-Hesperidin

Methyl Hesperidin is a flavanone glycoside (flavonoid) (C28H34O15) found abundantly in citrus fruits. Its aglycone form is called hesperetin.

Methyl-Hesperidin Chemical Structure

Methyl-Hesperidin Chemical Structure

CAS: 11013-97-1

Purity & Quality Control

Batch: S232301 DMSO] 100 mg/mL] false] Water] 100 mg/mL] false] Ethanol] Insoluble] false Purity: 99.55%
99.55

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Biological Activity

Description Methyl Hesperidin is a flavanone glycoside (flavonoid) (C28H34O15) found abundantly in citrus fruits. Its aglycone form is called hesperetin.
Targets
Akt [1] PKC [1]
In vitro
In vitro Methyl Hesperidin is a flavanone glycoside (flavonoid) (C28H34O15) found abundantly in citrus fruits. Its aglycone form is called hesperetin. Hesperidin and methyl hesperidin reduce TNF-alpha-induced VCAM-1 expression through inhibiting the phosphorylation of Akt and PKC. [1] Methyl hesperidin can bind to buman serum albumin (BSA) with binding constants between 18 and 34 mM/L. [2] Long-term carcinogenicity study demonstrates that methyl hesperidin shows no carcinogenicity for B6C3F1 mice in the 96-wk feeding regimen. [3]

Chemical Information & Solubility

Molecular Weight 624.59 Formula

C29H36O15
CAS No. 11013-97-1 SDF Download Methyl-Hesperidin SDF
Smiles CC1C(C(C(C(O1)OCC2C(C(C(C(O2)OC3=CC(=C4C(=O)CC(OC4=C3)C5=CC(=C(C=C5)OC)OC)O)O)O)O)O)O)O
Storage (From the date of receipt)

In vitro
Batch:

DMSO : 100 mg/mL ( (160.1 mM)； Moisture-absorbing DMSO reduces solubility. Please use fresh DMSO.)

Water : 100 mg/mL

Ethanol : Insoluble


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In vivo
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Method for preparing DMSO master liquid: mg drug pre-dissolved in μL DMSO ( Master liquid concentration mg/mL, Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug. )

Method for preparing in vivo formulation: Take μL DMSO master liquid, next addμL PEG300, mix and clarify, next addμL Tween 80, mix and clarify, next add μL ddH2O, mix and clarify.

Method for preparing in vivo formulation: Take μL DMSO master liquid, next add μL Corn oil, mix and clarify.

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