Sirtuin

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Sirtuin Inhibitors | Activators (4)

water-soluble

Cat.No. Product Name Information Product Citations Customer Reviews
S1129 SRT1720 SRT1720 is a selective SIRT1 activator with EC50 of 0.16 μM, but is >230-fold less potent for SIRT2 and SIRT3.
  • EMBO J, 2013, 32(6):791-804
  • Cancer Res, 2013, 74(1):298-308
  • J Biol Chem, 2011, 286(18):16101-8
S1541 EX 527 (Selisistat) EX 527 is a potent and selective SIRT1 inhibitor with IC50 of 38 nM, exhibits >200-fold selectivity against SIRT2 and SIRT3.
  • Cancer Res, 2013, 74(1):298-308
  • J Biol Chem, 2013, 288(22):15537-46
S1396 Resveratrol Resveratrol is a phytoalexin produced naturally by several plants with anti-cancer, anti-inflammatory, blood-sugar-lowering and other beneficial cardiovascular effects.
S2804 Sirtinol Sirtinol is a specific SIRT1 and SIRT2 inhibitor with IC50 of 131 μM and 38 μM, respectively.