Poly (ADP-ribose) polymerase

Cat.No. Product Name Feedback Added

S2197

A-966492

Jan 2011
A-966492 is a highly potent and efficacious poly(ADP-ribose) polymerase (PARP) inhibitor with a Ki and EC50 of 1 nM.
S1004

ABT-888 (Veliparib)

Apr 2009
ABT-888 (Veliparib) is a potent PARP inhibitor to PARP-1 and PARP-2 with Kis of 5.2 and 2.9 nmol.
S2178

AG14361

Jan 2011
AG14361 is a potent poly(ADP-ribose) polymerase (PARP-1) inhibitor with a GI50 of 10.9 µM.
S1087

BSI-201

Jul 2009
BSI-201 is a potent PARP1 inhibitor with strong anti-neoplastic effect.
S1132

INO-1001

Dec 2009
INO-1001 is a novel potent PARP inhibitor with an IC50 of 3 nM.
S2741

MK-4827 

Dec 2011
MK-4827 is a potent, selective PARP 1/2 inhibitor with IC50 of 3.8 and 2.1 nM for PARP1 and 2, respectively.
S1060

Olaparib (AZD2281)

Apr 2009
Olaparib (AZD2281) is a potent PARP inhibitor with IC50 of 5 and 1 nM for PARP-1and PARP-2, respectively.
S1098

Rucaparib (AG-014699 , PF-01367338)

Aug 2009
Rucaparib (AG-014699 , PF-01367338) is a PARP inhibitor (Ki, 1.4 nmol/L).
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Arnaud AUTRET, Trinity College
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Dongfeng Chen, The Rausing Lab
"Your product U0126(Cat.NO S1102) works well in our experiments. I hope I can get more excellent products from your company in future."

Dr. Alexandra Segref, CECAD Cologne,Germay
"I am very satisfied with your product and costumer service. Bortezomib works very well in our assay, it is comparably cheaper than other inhibitors that we tested is more reliable for our assays. We see a great effect by using 10nM concentration."

R.B. Cambridge
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Zhenghe John Wang Assistant Professor, Case Western Reserve University
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Philip Seeman, Toronto University
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