Tankyrase-1 Inhibitors

Catalog No. Product Name Information Selective / Pan IC50 / Ki
S1060 Olaparib (AZD2281, Ku-0059436)

Olaparib (AZD2281, KU0059436) is a selective inhibitor of PARP1/2 with IC50 of 5 nM/1 nM, 300-times less effective against tankyrase-1. Phase 3.

Pan Tankyrase-1, IC50: 1.5 μM