Tobramycin

Synonyms: NSC 180514,Deoxykanamycin B, Nebramycin Factor 6

Tobramycin (NSC 180514,Deoxykanamycin B, Nebramycin Factor 6) is an aminoglycoside antibiotic with an IC50 of 9.7 μM.

Tobramycin Chemical Structure

Tobramycin Chemical Structure

CAS: 32986-56-4

Selleck's Tobramycin has been cited by 1 publication

Purity & Quality Control

Batch: Purity: 99.87%
99.87

Tobramycin Related Products

Choose Selective Antineoplastic and Immunosuppressive Antibiotics Inhibitors

Biological Activity

Description Tobramycin (NSC 180514,Deoxykanamycin B, Nebramycin Factor 6) is an aminoglycoside antibiotic with an IC50 of 9.7 μM.
NCT Number Recruitment Conditions Sponsor/Collaborators Start Date Phases
NCT06016088 Not yet recruiting
Cystic Fibrosis Lung|Respiratory Infections Recurrent Chronic|Pseudomonas Aeruginosa
Respirion Pharmaceuticals Pty Ltd
December 2023 Phase 1|Phase 2
NCT05169229 Recruiting
Arthroplasty Replacement Hip|Osteoarthritis Hip|Antibiotic Resistant Infection|Prosthetic Joint Infection
University Hospital Linkoeping|Region Östergötland|The Swedish Research Council
April 1 2022 Phase 2|Phase 3
NCT04964947 Recruiting
Wound Infection|Fractures Open|Surgical Site Infection
Massachusetts General Hospital|United States Department of Defense
January 10 2022 Phase 3
NCT04297631 Completed
Antibotics in Cementless Knees
Washington University School of Medicine
February 14 2020 Phase 4
NCT03904836 Completed
Renal Dialysis|Renal Failure Chronic
Maisonneuve-Rosemont Hospital
January 31 2019 Phase 1

Chemical Information & Solubility

Molecular Weight 467.52369 Formula

C18H37N5O9

CAS No. 32986-56-4 SDF Download Tobramycin SDF
Smiles C1C(C(C(C(C1N)OC2C(C(C(C(O2)CO)O)N)O)O)OC3C(CC(C(O3)CN)O)N)N
Storage (From the date of receipt)

In vitro
Batch:

Water : 94 mg/mL

DMSO : Insoluble ( Moisture-absorbing DMSO reduces solubility. Please use fresh DMSO.)

Ethanol : Insoluble


Molecular Weight Calculator

In vivo
Batch:

Add solvents to the product individually and in order.


In vivo Formulation Calculator

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Molarity Calculator

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In vivo Formulation Calculator (Clear solution)

Step 1: Enter information below (Recommended: An additional animal making an allowance for loss during the experiment)

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Working concentration: mg/ml;

Method for preparing DMSO master liquid: mg drug pre-dissolved in μL DMSO ( Master liquid concentration mg/mL, Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug. )

Method for preparing in vivo formulation: Take μL DMSO master liquid, next addμL PEG300, mix and clarify, next addμL Tween 80, mix and clarify, next add μL ddH2O, mix and clarify.

Method for preparing in vivo formulation: Take μL DMSO master liquid, next add μL Corn oil, mix and clarify.

Note: 1. Please make sure the liquid is clear before adding the next solvent.
2. Be sure to add the solvent(s) in order. You must ensure that the solution obtained, in the previous addition, is a clear solution before proceeding to add the next solvent. Physical methods such
as vortex, ultrasound or hot water bath can be used to aid dissolving.

Tech Support

Answers to questions you may have can be found in the inhibitor handling instructions. Topics include how to prepare stock solutions, how to store inhibitors, and issues that need special attention for cell-based assays and animal experiments.

Handling Instructions

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