Puromycin 2HCl

Catalog No.S7417

Puromycin 2HCl Chemical Structure

Molecular Weight(MW): 544.43

Puromycin 2HCl is an aminonucleoside antibiotic, which acts as a protein synthesis inhibitor.

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Biological Activity

Description Puromycin 2HCl is an aminonucleoside antibiotic, which acts as a protein synthesis inhibitor.
In vitro

The antibiotic puromycin is produced by the actinoniycete, Streptornyces alboniger, and has been used as a tool for studying protein synthesis in a number of systems. [1] Puromycin can be used for the selection of recombinant cells from noncultured cells. [2]

Cell Data
Cell Lines Assay Type Concentration Incubation Time Formulation Activity Description PMID
human HepG2 cells Ml\DS5Jwf3SqIHnubIljcXSrb36gZZN{[Xl? NYHsc5hZPzJiaB?= M173Rmdzd3e2aDDpcohq[mm2aX;uJI9nKGi3bXHuJGhmeEd{IHPlcIx{KGGodHXyJFczKGi{czDifUBUWkJiYYPzZZktKEmFNUC9NE4zOSEQvF2u NIPTUm0yQDVzMkm4OC=>
human K562 cells M3\IT2dzd3e2aDDpcohq[mm2aX;uJIF{e2G7 MWC3NkBp NHTlTZNIem:5dHigbY5pcWKrdHnvckBw\iCqdX3hckBMPTZ{IHPlcIx{KGGodHXyJFczKGi{czDifUBUWkJiYYPzZZktKEmFNUC9NE4zOiEQvF2u MYOxPFMyOzNyNx?=
human HepG2 cells NH\kNGVIem:5dHigbY5pcWKrdHnvckBie3OjeR?= MmC2O|IhcA>? M2n1Wmdzd3e2aDDpcohq[mm2aX;uJI9nKGi3bXHuJGhmeEd{IHPlcIx{KGGodHXyJFczKGi{czDifUBOXFRiYYPzZZktKEmFNUC9NE4zOyEQvF2u M4SzTVE5OzF|M{C3
HEK239 cells NGXEUldEgXSxdH;4bYPDqGG|c3H5 M1[2N|czKGh? M3;WOGN6fG:2b4jpZ4l1gSCjZ3HpcpN1KEiHS{KzPUBk\WyuczDh[pRmeiB5MjDodpMh[nliQXzhcYFzKGKudXWgZZN{[XluIFnDOVA:OC52MjFOwG0v MlvxNlA2PThyNkC=
human hepatocellular carcinoma cell line (Huh7) MXLDfZRwfG:6aXRCpIF{e2G7 NGnJZ2pPV1[DUmTJV|ohS3m2b4TvfIlkcXS7IHHnZYlve3RiaIXtZY4hcGWyYYTvZ4VtdHWuYYKgZ4Fz[2mwb33hJINmdGxibHnu[UApUHWqNzmsJGNEPTB;Nj62N{DPxE1w M1vMR|E5PTd7N{iz
mouse J774A1 cells M2H3OWN6fG:2b4jpZ:Kh[XO|YYm= MUjDfZRwfG:6aXPpeJkh[WejaX7zeEBud3W|ZTDKO|c1STFiY3XscJMh[nlidIL5dIFvKGKudXWg[ZhkdHW|aX;uJIF{e2G7LDDJR|UxRTFyIN88UU4> NIjMW3ozOjl|NE[zOi=>
human K562 cells MoewS5Jwf3SqIHnubIljcXSrb36gZZN{[Xl? MXO3NkBp NFTFWVVIem:5dHigbY5pcWKrdHnvckBw\iCmb4jvdpVjcWOrbj3y[ZNqe3SjboSgbJVu[W5iS{W2NkBk\WyuczDh[pRmeiB5MjDodpMh[nliU2LCJIF{e2G7LDDJR|UxRTJ4LkizJO69VS5? MnvONVg{OTN|MEe=

... Click to View More Cell Line Experimental Data

Protocol

Solubility (25°C)

In vitro DMSO 100 mg/mL warmed (183.67 mM)
Water 100 mg/mL warmed (183.67 mM)
Ethanol Insoluble

* Please note that Selleck tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.

Chemical Information

Molecular Weight 544.43
Formula

C22H29N7O5.2HCl

CAS No. 58-58-2
Storage powder
in solvent
Synonyms N/A

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Tech Support

Answers to questions you may have can be found in the inhibitor handling instructions. Topics include how to prepare stock solutions, how to store inhibitors, and issues that need special attention for cell-based assays and animal experiments.

Handling Instructions

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Cell Lines Assay Type Concentration Incubation Time Formulation Activity Description PMID