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Fasudil HCl (HA-1077) Chemical Structure
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Biological Activity
Fasudil HCl is cyclic nucleotide-dependent protein kinase inhibitor and Rho-associated kinase inhibitor with an IC50 of 10.7 μM. It is also a Ca2+ antagonist and vasodilator. It also inhibits proliferation of vascular smooth muscle cells. [1]
References on Fasudil HCl (HA-1077)
- [1] Acta Neurochir Suppl. 2001;77:201-4.
Chemical Information
| Molecular Weight (WM): | 327.83 |
|---|---|
| Formula: | C14H17N3O2S.HCl |
| CAS No.: | 105628-07-7 |
| Synonyms: |
AT-877
|
| Dissolve in (25°C): | DMSO ≥66mg/mL |
| Water ≥66mg/mL | |
| Ethanol ≥3mg/mL | |
| Storage: | 2 years-20°CPowder |
| 1 week-4°Cin DMSO | |
| 1 month-80°in DMSO |
Quality Control & MSDS
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