GSK269962 HCl

Catalog No.S7687 Synonyms: GSK269962A, GSK269962B

GSK269962 HCl Chemical Structure

Molecular Weight(MW): 607.06

GSK269962 is a selective ROCK(Rho-associated protein kinase) inhibitor with IC50 values of 1.6 and 4 nM for ROCK1 and ROCK2, respectively.

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Purity & Quality Control

Choose Selective ROCK Inhibitors

Biological Activity

Description GSK269962 is a selective ROCK(Rho-associated protein kinase) inhibitor with IC50 values of 1.6 and 4 nM for ROCK1 and ROCK2, respectively.
Targets
ROCK1 [1]
(Cell-free assay)
ROCK2 [1]
(Cell-free assay)
MSK1 [1]
(Cell-free assay)
RSK1 [1]
(Cell-free assay)
1.6 nM 4 nM 49 nM 132 nM
In vitro

GSK269962A completely abolished the actin stress fiber formation induced by angiotensin II in human smooth muscles. Such suppressive effect on actin fiber formation was observed beginning at around 1 μM GSK269962A. GSK269962A induced vasorelaxation in preconstricted rat aorta(tissue baths) with an IC50 of 35 nM. the relaxation induced by GSK269962A is reversible. GSK269962A suppressed IL-6 mRNA transcription and reduced LPS-induced IL-6 and TNF-α protein production in macrophages[1].

Cell Data
Cell Lines Assay Type Concentration Incubation Time Formulation Activity Description PMID
NCI-H1581 NIi4PIVIem:5dHigbY5pcWKrdHnvckBie3OjeR?= NEfpTZpKdmirYnn0bY9vKG:oIHj1cYFvKE6FST3INVU5OSClZXzsJIdzd3e2aDDpckBiKGOnbHygeoli[mmuaYT5JIF{e2G7LDDJR|UxRTF6Lki0O|ch|ryP MV;TRW5ITVJ?
NCI-H1694 NHjmcoZIem:5dHigbY5pcWKrdHnvckBie3OjeR?= NET6eW5KdmirYnn0bY9vKG:oIHj1cYFvKE6FST3INVY6PCClZXzsJIdzd3e2aDDpckBiKGOnbHygeoli[mmuaYT5JIF{e2G7LDDJR|UxRTJ2Lki3OFkh|ryP M1PvR3NCVkeHUh?=
NCI-H1963 MoPjS5Jwf3SqIHnubIljcXSrb36gZZN{[Xl? NEfXSoJKdmirYnn0bY9vKG:oIHj1cYFvKE6FST3INVk3OyClZXzsJIdzd3e2aDDpckBiKGOnbHygeoli[mmuaYT5JIF{e2G7LDDJR|UxRTFwMke4N|kh|ryP MVnTRW5ITVJ?
NCI-H2081 MVHHdo94fGhiaX7obYJqfGmxbjDhd5NigQ>? Ml7JTY5pcWKrdHnvckBw\iCqdX3hckBPS0lvSEKwPFEh[2WubDDndo94fGhiaX6gZUBk\WyuII\pZYJqdGm2eTDhd5NigSxiSVO1NF0{PC54MES0JO69VQ>? NVTWc41LW0GQR1XS
NCI-H209 NFja[5VIem:5dHigbY5pcWKrdHnvckBie3OjeR?= MUnJcohq[mm2aX;uJI9nKGi3bXHuJG5EUS2KMkC5JINmdGxiZ4Lve5RpKGmwIHGgZ4VtdCC4aXHibYxqfHliYYPzZZktKEmFNUC9NlIvPjJ5MjFOwG0> M1v5c3NCVkeHUh?=
NCI-H2107 NXH6eFByT3Kxd4ToJIlvcGmkaYTpc44h[XO|YYm= NVq5SHh[UW6qaXLpeIlwdiCxZjDoeY1idiCQQ1mtTFIyODdiY3XscEBoem:5dHigbY4h[SClZXzsJJZq[WKrbHn0fUBie3OjeTygTWM2OD1{NT62OVYyKM7:TR?= NWTBdFNiW0GQR1XS
NCI-H2126 NYPNc|JHT3Kxd4ToJIlvcGmkaYTpc44h[XO|YYm= MWPJcohq[mm2aX;uJI9nKGi3bXHuJG5EUS2KMkGyOkBk\WyuIHfyc5d1cCCrbjDhJINmdGxidnnhZoltcXS7IHHzd4F6NCCLQ{WwQVYvPTB2Mk[g{txO MnizV2FPT0WU
NCI-H2171 Mlf0S5Jwf3SqIHnubIljcXSrb36gZZN{[Xl? MoPqTY5pcWKrdHnvckBw\iCqdX3hckBPS0lvSEKxO|Eh[2WubDDndo94fGhiaX6gZUBk\WyuII\pZYJqdGm2eTDhd5NigSxiSVO1NF0xNjl3OUO3JO69VQ>? MmXWV2FPT0WU
NCI-H2227 M2TxTWdzd3e2aDDpcohq[mm2aX;uJIF{e2G7 NVLmV2JvUW6qaXLpeIlwdiCxZjDoeY1idiCQQ1mtTFIzOjdiY3XscEBoem:5dHigbY4h[SClZXzsJJZq[WKrbHn0fUBie3OjeTygTWM2OD15Lki4OlE3KM7:TR?= MXHTRW5ITVJ?
NCI-H524 Mn2zS5Jwf3SqIHnubIljcXSrb36gZZN{[Xl? NEiybHBKdmirYnn0bY9vKG:oIHj1cYFvKE6FST3IOVI1KGOnbHyg[5Jwf3SqIHnuJIEh[2WubDD2bYFjcWyrdImgZZN{[XluIFnDOVA:OjJwOEe2N{DPxE1? M4DVUHNCVkeHUh?=
NCI-H526 M1P3dGdzd3e2aDDpcohq[mm2aX;uJIF{e2G7 Mn;PTY5pcWKrdHnvckBw\iCqdX3hckBPS0lvSEWyOkBk\WyuIHfyc5d1cCCrbjDhJINmdGxidnnhZoltcXS7IHHzd4F6NCCLQ{WwQVE5NjV2M{Gg{txO M2rTcXNCVkeHUh?=
NCI-H720 MmL4S5Jwf3SqIHnubIljcXSrb36gZZN{[Xl? NXywXVRbUW6qaXLpeIlwdiCxZjDoeY1idiCQQ1mtTFczOCClZXzsJIdzd3e2aDDpckBiKGOnbHygeoli[mmuaYT5JIF{e2G7LDDJR|UxRTJwNEWxOlEh|ryP MkfEV2FPT0WU
NMC-G1 NYm2SJd5T3Kxd4ToJIlvcGmkaYTpc44h[XO|YYm= NHe4SnZKdmirYnn0bY9vKG:oIHj1cYFvKE6PQz3HNUBk\WyuIHfyc5d1cCCrbjDhJINmdGxidnnhZoltcXS7IHHzd4F6NCCLQ{WwQVE2NjB3N{ig{txO MXjTRW5ITVJ?
NOS-1 cell NWTqepJiT3Kxd4ToJIlvcGmkaYTpc44h[XO|YYm= MUDJcohq[mm2aX;uJI9nKGi3bXHuJG5QWy1zIHPlcIwh\3Kxd4ToJIlvKGFiY3XscEB3cWGkaXzpeJkh[XO|YYmsJGlEPTB;NT64NlI6PCEQvF2= MoX4V2FPT0WU
OCI-AML2 cell NHOxOZJIem:5dHigbY5pcWKrdHnvckBie3OjeR?= NXW1V5FMUW6qaXLpeIlwdiCxZjDoeY1idiCRQ1mtRW1NOiClZXzsJIdzd3e2aDDpckBiKGOnbHygeoli[mmuaYT5JIF{e2G7LDDJR|UxRTFyLkm0PVYh|ryP NV64PXIyW0GQR1XS
OCUB-M cell NYXWSlJyT3Kxd4ToJIlvcGmkaYTpc44h[XO|YYm= MoLpTY5pcWKrdHnvckBw\iCqdX3hckBQS1WELV2gZ4VtdCCpcn;3eIghcW5iYTDj[YxtKH[rYXLpcIl1gSCjc4PhfUwhUUN3ME2xO{4zODFizszN MmLYV2FPT0WU
ONS-76 cell NGjnNYFIem:5dHigbY5pcWKrdHnvckBie3OjeR?= NVfCSWw1UW6qaXLpeIlwdiCxZjDoeY1idiCRTmOtO|Yh[2WubDDndo94fGhiaX6gZUBk\WyuII\pZYJqdGm2eTDhd5NigSxiSVO1NF0yOy57MUmxJO69VQ>? MlTCV2FPT0WU
OS-RC-2 cell MoTuS5Jwf3SqIHnubIljcXSrb36gZZN{[Xl? M1HtZWlvcGmkaYTpc44hd2ZiaIXtZY4hV1NvUlOtNkBk\WyuIHfyc5d1cCCrbjDhJINmdGxidnnhZoltcXS7IHHzd4F6NCCLQ{WwQVQ3NjF7NTFOwG0> Ml3NV2FPT0WU
OVCAR-4 cell M125V2dzd3e2aDDpcohq[mm2aX;uJIF{e2G7 Mo\qTY5pcWKrdHnvckBw\iCqdX3hckBQXkODUj20JINmdGxiZ4Lve5RpKGmwIHGgZ4VtdCC4aXHibYxqfHliYYPzZZktKEmFNUC9PE44OThyODFOwG0> M4\YRXNCVkeHUh?=
P30-OHK cell M1ryXmdzd3e2aDDpcohq[mm2aX;uJIF{e2G7 NH[4XYFKdmirYnn0bY9vKG:oIHj1cYFvKFB|MD3PTGsh[2WubDDndo94fGhiaX6gZUBk\WyuII\pZYJqdGm2eTDhd5NigSxiSVO1NF04NjZ{OEe3JO69VQ>? NX3lOVN6W0GQR1XS
P30-OHK cell NFj2Z|lIem:5dHigbY5pcWKrdHnvckBie3OjeR?= Ml\aTY5pcWKrdHnvckBw\iCqdX3hckBRTi1|OEKgZ4VtdCCpcn;3eIghcW5iYTDj[YxtKH[rYXLpcIl1gSCjc4PhfUwhUUN3ME23MlA1QTV2IN88US=> NHjKNHFUSU6JRWK=
PSN1 cell NGmzVFBIem:5dHigbY5pcWKrdHnvckBie3OjeR?= Mnm5TY5pcWKrdHnvckBw\iCqdX3hckBRW05zIHPlcIwh\3Kxd4ToJIlvKGFiY3XscEB3cWGkaXzpeJkh[XO|YYmsJGlEPTB;Nj6yNlEzPiEQvF2= NHzlVnhUSU6JRWK=
QIMR-WIL cell MlTRS5Jwf3SqIHnubIljcXSrb36gZZN{[Xl? NV\UNZZ7UW6qaXLpeIlwdiCxZjDoeY1idiCTSV3SMXdKVCClZXzsJIdzd3e2aDDpckBiKGOnbHygeoli[mmuaYT5JIF{e2G7LDDJR|UxRTBwNEmwNFQh|ryP MU\TRW5ITVJ?
RCC10RGB cell M3nKUmdzd3e2aDDpcohq[mm2aX;uJIF{e2G7 NF;qdI1KdmirYnn0bY9vKG:oIHj1cYFvKFKFQ{GwVmdDKGOnbHyg[5Jwf3SqIHnuJIEh[2WubDD2bYFjcWyrdImgZZN{[XluIFnDOVA:OThwOUCzOkDPxE1? MV;TRW5ITVJ?
RKO cell NEXWbZlIem:5dHigbY5pcWKrdHnvckBie3OjeR?= NYm1WIIzUW6qaXLpeIlwdiCxZjDoeY1idiCUS1:gZ4VtdCCpcn;3eIghcW5iYTDj[YxtKH[rYXLpcIl1gSCjc4PhfUwhUUN3ME2xNE42PjZ{IN88US=> Mmn2V2FPT0WU
RL95-2 cell MUjHdo94fGhiaX7obYJqfGmxbjDhd5NigQ>? NYPDRVk3UW6qaXLpeIlwdiCxZjDoeY1idiCUTEm1MVIh[2WubDDndo94fGhiaX6gZUBk\WyuII\pZYJqdGm2eTDhd5NigSxiSVO1NF0yOC54NzFOwG0> MmOxV2FPT0WU
RPMI-6666 cell MlvOS5Jwf3SqIHnubIljcXSrb36gZZN{[Xl? MoXKTY5pcWKrdHnvckBw\iCqdX3hckBTWE2LLU[2OlYh[2WubDDndo94fGhiaX6gZUBk\WyuII\pZYJqdGm2eTDhd5NigSxiSVO1NF0yQC53MkO2JO69VQ>? NVjwPVNRW0GQR1XS
RPMI-8402 cell NWjxRXBLT3Kxd4ToJIlvcGmkaYTpc44h[XO|YYm= NVPLfHZYUW6qaXLpeIlwdiCxZjDoeY1idiCUUF3JMVg1ODJiY3XscEBoem:5dHigbY4h[SClZXzsJJZq[WKrbHn0fUBie3OjeTygTWM2OD12LkW4OVYh|ryP NX;MNHVNW0GQR1XS
RXF393 cell Mn32S5Jwf3SqIHnubIljcXSrb36gZZN{[Xl? Ml3STY5pcWKrdHnvckBw\iCqdX3hckBTYEZ|OUOgZ4VtdCCpcn;3eIghcW5iYTDj[YxtKH[rYXLpcIl1gSCjc4PhfUwhUUN3ME2wMlM6OyEQvF2= MV\TRW5ITVJ?
Ramos-2G6-4C10 cell MWDHdo94fGhiaX7obYJqfGmxbjDhd5NigQ>? NYH5e5NGUW6qaXLpeIlwdiCxZjDoeY1idiCUYX3vd{0zTzZvNFOxNEBk\WyuIHfyc5d1cCCrbjDhJINmdGxidnnhZoltcXS7IHHzd4F6NCCLQ{WwQVEvOzV5IN88US=> NXzuO2FIW0GQR1XS
SCLC-21H cell NXLidnkxT3Kxd4ToJIlvcGmkaYTpc44h[XO|YYm= NWf6bWZsUW6qaXLpeIlwdiCxZjDoeY1idiCVQ1zDMVIyUCClZXzsJIdzd3e2aDDpckBiKGOnbHygeoli[mmuaYT5JIF{e2G7LDDJR|UxRTdwNkGxOFkh|ryP M2K3d3NCVkeHUh?=
SF126 cell NXvqOldCT3Kxd4ToJIlvcGmkaYTpc44h[XO|YYm= M3LPbGlvcGmkaYTpc44hd2ZiaIXtZY4hW0ZzMk[gZ4VtdCCpcn;3eIghcW5iYTDj[YxtKH[rYXLpcIl1gSCjc4PhfUwhUUN3ME2xNU45OzJzzszN MWnTRW5ITVJ?
SF268 cell M3;rNWdzd3e2aDDpcohq[mm2aX;uJIF{e2G7 MXHJcohq[mm2aX;uJI9nKGi3bXHuJHNHOjZ6IHPlcIwh\3Kxd4ToJIlvKGFiY3XscEB3cWGkaXzpeJkh[XO|YYmsJGlEPTB;Nj6yN|E5OyEQvF2= MWDTRW5ITVJ?
SF539 cell MUfHdo94fGhiaX7obYJqfGmxbjDhd5NigQ>? MkfnTY5pcWKrdHnvckBw\iCqdX3hckBUTjV|OTDj[YxtKGe{b4f0bEBqdiCjIHPlcIwhfmmjYnnsbZR6KGG|c3H5MEBKSzVyPUGuNlg3PjFizszN M{Ps[HNCVkeHUh?=
SH-4 cell NInDeXpIem:5dHigbY5pcWKrdHnvckBie3OjeR?= MXfJcohq[mm2aX;uJI9nKGi3bXHuJHNJNTRiY3XscEBoem:5dHigbY4h[SClZXzsJJZq[WKrbHn0fUBie3OjeTygTWM2OD13Lke1OVA5KM7:TR?= NFfMeVhUSU6JRWK=
SIG-M5 cell NHXSZpNIem:5dHigbY5pcWKrdHnvckBie3OjeR?= Mo\yTY5pcWKrdHnvckBw\iCqdX3hckBUUUdvTUWgZ4VtdCCpcn;3eIghcW5iYTDj[YxtKH[rYXLpcIl1gSCjc4PhfUwhUUN3ME2xNU44OjV7IN88US=> NVrEcow{W0GQR1XS
SJSA-1 cell M2HNeGdzd3e2aDDpcohq[mm2aX;uJIF{e2G7 M4HT[2lvcGmkaYTpc44hd2ZiaIXtZY4hW0qVQT2xJINmdGxiZ4Lve5RpKGmwIHGgZ4VtdCC4aXHibYxqfHliYYPzZZktKEmFNUC9NU4xPDV{NjFOwG0> M2HjWXNCVkeHUh?=
SK-LMS-1 cell NES3RZpIem:5dHigbY5pcWKrdHnvckBie3OjeR?= NV;Cb3J5UW6qaXLpeIlwdiCxZjDoeY1idiCVSz3MUXMuOSClZXzsJIdzd3e2aDDpckBiKGOnbHygeoli[mmuaYT5JIF{e2G7LDDJR|UxRTN{LkW5OlUh|ryP M2LxSXNCVkeHUh?=
SK-MM-2 cell M{jIV2dzd3e2aDDpcohq[mm2aX;uJIF{e2G7 MWTJcohq[mm2aX;uJI9nKGi3bXHuJHNMNU2PLUKgZ4VtdCCpcn;3eIghcW5iYTDj[YxtKH[rYXLpcIl1gSCjc4PhfUwhUUN3ME20Nk4{PDB3IN88US=> NEPuW5ZUSU6JRWK=
SK-N-DZ cell NYOzb3Z1T3Kxd4ToJIlvcGmkaYTpc44h[XO|YYm= MWjJcohq[mm2aX;uJI9nKGi3bXHuJHNMNU5vRGqgZ4VtdCCpcn;3eIghcW5iYTDj[YxtKH[rYXLpcIl1gSCjc4PhfUwhUUN3ME25MlQ5OzF2IN88US=> MY\TRW5ITVJ?
SK-NEP-1 cell M{TXVGdzd3e2aDDpcohq[mm2aX;uJIF{e2G7 MUPJcohq[mm2aX;uJI9nKGi3bXHuJHNMNU6HUD2xJINmdGxiZ4Lve5RpKGmwIHGgZ4VtdCC4aXHibYxqfHliYYPzZZktKEmFNUC9NVcvPTR3NjFOwG0> M{PxTXNCVkeHUh?=
SK-PN-DW cell NUfzd3BtT3Kxd4ToJIlvcGmkaYTpc44h[XO|YYm= MXfJcohq[mm2aX;uJI9nKGi3bXHuJHNMNVCQLVTXJINmdGxiZ4Lve5RpKGmwIHGgZ4VtdCC4aXHibYxqfHliYYPzZZktKEmFNUC9NlQvQTd|NjFOwG0> M4nie3NCVkeHUh?=
SNB75 cell NWX5TnVCT3Kxd4ToJIlvcGmkaYTpc44h[XO|YYm= NXzD[YYzUW6qaXLpeIlwdiCxZjDoeY1idiCVTlK3OUBk\WyuIHfyc5d1cCCrbjDhJINmdGxidnnhZoltcXS7IHHzd4F6NCCLQ{WwQVgvODd5M{eg{txO MkixV2FPT0WU
SR cell NXG0cYF{T3Kxd4ToJIlvcGmkaYTpc44h[XO|YYm= NEewOWFKdmirYnn0bY9vKG:oIHj1cYFvKFOUIHPlcIwh\3Kxd4ToJIlvKGFiY3XscEB3cWGkaXzpeJkh[XO|YYmsJGlEPTB;MD6wNFAyOzdizszN M2fOWHNCVkeHUh?=
SU-DHL-1 cell Ml\XS5Jwf3SqIHnubIljcXSrb36gZZN{[Xl? M17iZWlvcGmkaYTpc44hd2ZiaIXtZY4hW1VvRFjMMVEh[2WubDDndo94fGhiaX6gZUBk\WyuII\pZYJqdGm2eTDhd5NigSxiSVO1NF0yOi55M{O2JO69VQ>? NVvBcJhMW0GQR1XS
SW684 cell MVTHdo94fGhiaX7obYJqfGmxbjDhd5NigQ>? MlTPTY5pcWKrdHnvckBw\iCqdX3hckBUXzZ6NDDj[YxtKGe{b4f0bEBqdiCjIHPlcIwhfmmjYnnsbZR6KGG|c3H5MEBKSzVyPUO5MlAyOSEQvF2= NXT0bVBGW0GQR1XS
SW872 cell NWSxO2RHT3Kxd4ToJIlvcGmkaYTpc44h[XO|YYm= NWW2Z4tMUW6qaXLpeIlwdiCxZjDoeY1idiCVV{i3NkBk\WyuIHfyc5d1cCCrbjDhJINmdGxidnnhZoltcXS7IHHzd4F6NCCLQ{WwQVAvQDh4NU[g{txO NGrHXHNUSU6JRWK=
SW962 cell M{W2S2dzd3e2aDDpcohq[mm2aX;uJIF{e2G7 MnG2TY5pcWKrdHnvckBw\iCqdX3hckBUXzl4MjDj[YxtKGe{b4f0bEBqdiCjIHPlcIwhfmmjYnnsbZR6KGG|c3H5MEBKSzVyPUGyMlc2OjFizszN MYPTRW5ITVJ?
697 cell M1PvU2dzd3e2aDDpcohq[mm2aX;uJIF{e2G7 MnXGTY5pcWKrdHnvckBw\iCqdX3hckA3QTdiY3XscEBoem:5dHigbY4h[SClZXzsJJZq[WKrbHn0fUBie3OjeTygTWM2OD1yLkK5PVEh|ryP MWXTRW5ITVJ?
8-MG-BA cell MYTHdo94fGhiaX7obYJqfGmxbjDhd5NigQ>? NWTEWFI3UW6qaXLpeIlwdiCxZjDoeY1idiB6LV3HMWJCKGOnbHyg[5Jwf3SqIHnuJIEh[2WubDD2bYFjcWyrdImgZZN{[XluIFnDOVA:OjNwMEe5N{DPxE1? M1XPSnNCVkeHUh?=
A101D cell NHi5cIFIem:5dHigbY5pcWKrdHnvckBie3OjeR?= MkjETY5pcWKrdHnvckBw\iCqdX3hckBCOTBzRDDj[YxtKGe{b4f0bEBqdiCjIHPlcIwhfmmjYnnsbZR6KGG|c3H5MEBKSzVyPUGuPFcxOzRizszN NHvCV5lUSU6JRWK=
ACN cell M1PscWdzd3e2aDDpcohq[mm2aX;uJIF{e2G7 M1\MfGlvcGmkaYTpc44hd2ZiaIXtZY4hSUOQIHPlcIwh\3Kxd4ToJIlvKGFiY3XscEB3cWGkaXzpeJkh[XO|YYmsJGlEPTB;MkGuOFM5PyEQvF2= MWDTRW5ITVJ?
AM-38 cell M1:3VGdzd3e2aDDpcohq[mm2aX;uJIF{e2G7 MnWwTY5pcWKrdHnvckBw\iCqdX3hckBCVS1|ODDj[YxtKGe{b4f0bEBqdiCjIHPlcIwhfmmjYnnsbZR6KGG|c3H5MEBKSzVyPUeuNlY{OjdizszN MUTTRW5ITVJ?
ATN-1 cell MUjHdo94fGhiaX7obYJqfGmxbjDhd5NigQ>? MoXoTY5pcWKrdHnvckBw\iCqdX3hckBCXE5vMTDj[YxtKGe{b4f0bEBqdiCjIHPlcIwhfmmjYnnsbZR6KGG|c3H5MEBKSzVyPUK0Mlc2PTVizszN NG\yd3ZUSU6JRWK=
BB30-HNC cell M4TWcGdzd3e2aDDpcohq[mm2aX;uJIF{e2G7 MV7Jcohq[mm2aX;uJI9nKGi3bXHuJGJDOzBvSF7DJINmdGxiZ4Lve5RpKGmwIHGgZ4VtdCC4aXHibYxqfHliYYPzZZktKEmFNUC9NlIvOjV|MjFOwG0> MlSyV2FPT0WU
BB49-HNC cell M1;z[mdzd3e2aDDpcohq[mm2aX;uJIF{e2G7 MkG0TY5pcWKrdHnvckBw\iCqdX3hckBDSjR7LVjOR{Bk\WyuIHfyc5d1cCCrbjDhJINmdGxidnnhZoltcXS7IHHzd4F6NCCLQ{WwQVAvODB5OEmg{txO NIXq[IhUSU6JRWK=
human BC-1 cell NYDVd2U5T3Kxd4ToJIlvcGmkaYTpc44h[XO|YYm= M4fBfWlvcGmkaYTpc44hd2ZiaIXtZY4hSkNvMTDj[YxtKGe{b4f0bEBqdiCjIHPlcIwhfmmjYnnsbZR6KGG|c3H5MEBKSzVyPUOuPVcyODdizszN NHK5bIdUSU6JRWK=
BE-13 cell NF3Xd5BIem:5dHigbY5pcWKrdHnvckBie3OjeR?= MmLPTY5pcWKrdHnvckBw\iCqdX3hckBDTS1zMzDj[YxtKGe{b4f0bEBqdiCjIHPlcIwhfmmjYnnsbZR6KGG|c3H5MEBKSzVyPUCuNVQxQDIQvF2= M4TVenNCVkeHUh?=
BL-70 cell NWrkdlJuT3Kxd4ToJIlvcGmkaYTpc44h[XO|YYm= MUjJcohq[mm2aX;uJI9nKGi3bXHuJGJNNTdyIHPlcIwh\3Kxd4ToJIlvKGFiY3XscEB3cWGkaXzpeJkh[XO|YYmsJGlEPTB;Mz60NFcxOyEQvF2= NXr4PZVvW0GQR1XS
BV-173 cell MknjS5Jwf3SqIHnubIljcXSrb36gZZN{[Xl? NISyPFZKdmirYnn0bY9vKG:oIHj1cYFvKEKYLUG3N{Bk\WyuIHfyc5d1cCCrbjDhJINmdGxidnnhZoltcXS7IHHzd4F6NCCLQ{WwQVE5Njh6NUmg{txO M1u3PHNCVkeHUh?=
Becker cell NEjSe|RIem:5dHigbY5pcWKrdHnvckBie3OjeR?= MlvkTY5pcWKrdHnvckBw\iCqdX3hckBD\WOtZYKgZ4VtdCCpcn;3eIghcW5iYTDj[YxtKH[rYXLpcIl1gSCjc4PhfUwhUUN3ME2xN{46PTR3IN88US=> MYPTRW5ITVJ?
CAL-148 cell MUnHdo94fGhiaX7obYJqfGmxbjDhd5NigQ>? NFT1W2hKdmirYnn0bY9vKG:oIHj1cYFvKEODTD2xOFgh[2WubDDndo94fGhiaX6gZUBk\WyuII\pZYJqdGm2eTDhd5NigSxiSVO1NF0{PS54NUW3JO69VQ>? MYrTRW5ITVJ?
TE-10 cell MX;Hdo94fGhiaX7obYJqfGmxbjDhd5NigQ>? MmnsTY5pcWKrdHnvckBw\iCqdX3hckBVTS1zMDDj[YxtKGe{b4f0bEBqdiCjIHPlcIwhfmmjYnnsbZR6KGG|c3H5MEBKSzVyPUKyMlg1OjNizszN NXTMS3Q3W0GQR1XS
TE-12 cell NF\qXIJIem:5dHigbY5pcWKrdHnvckBie3OjeR?= MnzsTY5pcWKrdHnvckBw\iCqdX3hckBVTS1zMjDj[YxtKGe{b4f0bEBqdiCjIHPlcIwhfmmjYnnsbZR6KGG|c3H5MEBKSzVyPUOyMlQyOTRizszN M3nsNXNCVkeHUh?=
TE-8 cell M3;1cWdzd3e2aDDpcohq[mm2aX;uJIF{e2G7 MXHJcohq[mm2aX;uJI9nKGi3bXHuJHRGNThiY3XscEBoem:5dHigbY4h[SClZXzsJJZq[WKrbHn0fUBie3OjeTygTWM2OD1zMT62NFg6KM7:TR?= MmX5V2FPT0WU
TE-9 cell NV7PcpF[T3Kxd4ToJIlvcGmkaYTpc44h[XO|YYm= NGXxUpdKdmirYnn0bY9vKG:oIHj1cYFvKFSHLUmgZ4VtdCCpcn;3eIghcW5iYTDj[YxtKH[rYXLpcIl1gSCjc4PhfUwhUUN3ME2zOk43OzhzIN88US=> MWPTRW5ITVJ?
TGW cell M3rs[Wdzd3e2aDDpcohq[mm2aX;uJIF{e2G7 NVPEfHBjUW6qaXLpeIlwdiCxZjDoeY1idiCWR2egZ4VtdCCpcn;3eIghcW5iYTDj[YxtKH[rYXLpcIl1gSCjc4PhfUwhUUN3ME2yN{4{PTd5IN88US=> NFjzRmRUSU6JRWK=
UACC-257 cell M2\KRmdzd3e2aDDpcohq[mm2aX;uJIF{e2G7 NVz4VlBXUW6qaXLpeIlwdiCxZjDoeY1idiCXQVPDMVI2PyClZXzsJIdzd3e2aDDpckBiKGOnbHygeoli[mmuaYT5JIF{e2G7LDDJR|UxRThwN{C2NlUh|ryP MlW4V2FPT0WU
WSU-NHL cell MX;Hdo94fGhiaX7obYJqfGmxbjDhd5NigQ>? MlqzTY5pcWKrdHnvckBw\iCqdX3hckBYW1VvTljMJINmdGxiZ4Lve5RpKGmwIHGgZ4VtdCC4aXHibYxqfHliYYPzZZktKEmFNUC9NlcvOTlyNzFOwG0> M3[wR3NCVkeHUh?=
no-10 cell M{PlSGdzd3e2aDDpcohq[mm2aX;uJIF{e2G7 M{DKeGlvcGmkaYTpc44hd2ZiaIXtZY4hdm9vMUCgZ4VtdCCpcn;3eIghcW5iYTDj[YxtKH[rYXLpcIl1gSCjc4PhfUwhUUN3ME2wMlY3QDR4IN88US=> MULTRW5ITVJ?
no-11 cell M4jvcWdzd3e2aDDpcohq[mm2aX;uJIF{e2G7 NHT1fZZKdmirYnn0bY9vKG:oIHj1cYFvKG6xLUGxJINmdGxiZ4Lve5RpKGmwIHGgZ4VtdCC4aXHibYxqfHliYYPzZZktKEmFNUC9OFcvODJ4MzFOwG0> NV;M[mVpW0GQR1XS
CAS-1 cell NXTYVJd[T3Kxd4ToJIlvcGmkaYTpc44h[XO|YYm= Mn73TY5pcWKrdHnvckBw\iCqdX3hckBESVNvMTDj[YxtKGe{b4f0bEBqdiCjIHPlcIwhfmmjYnnsbZR6KGG|c3H5MEBKSzVyPUCuPFQ4KM7:TR?= MoeyV2FPT0WU
CCRF-CEM cell MV;Hdo94fGhiaX7obYJqfGmxbjDhd5NigQ>? M2LUfWlvcGmkaYTpc44hd2ZiaIXtZY4hS0OURj3DSW0h[2WubDDndo94fGhiaX6gZUBk\WyuII\pZYJqdGm2eTDhd5NigSxiSVO1NF05NjZ3M{myJO69VQ>? NF:wUJZUSU6JRWK=
CMK cell M1vXV2dzd3e2aDDpcohq[mm2aX;uJIF{e2G7 M2H4O2lvcGmkaYTpc44hd2ZiaIXtZY4hS02NIHPlcIwh\3Kxd4ToJIlvKGFiY3XscEB3cWGkaXzpeJkh[XO|YYmsJGlEPTB;MT6wNVMzOyEQvF2= MVLTRW5ITVJ?
COLO-829 cell MmDKS5Jwf3SqIHnubIljcXSrb36gZZN{[Xl? NIXldpZKdmirYnn0bY9vKG:oIHj1cYFvKEORTF:tPFI6KGOnbHyg[5Jwf3SqIHnuJIEh[2WubDD2bYFjcWyrdImgZZN{[XluIFnDOVA:Oy5{NEKyOkDPxE1? NYLKbFZ5W0GQR1XS
COR-L279 cell MVrHdo94fGhiaX7obYJqfGmxbjDhd5NigQ>? MV3Jcohq[mm2aX;uJI9nKGi3bXHuJGNQWi2OMke5JINmdGxiZ4Lve5RpKGmwIHGgZ4VtdCC4aXHibYxqfHliYYPzZZktKEmFNUC9Nk4xPzN6IN88US=> M{\wTnNCVkeHUh?=
CP66-MEL cell M3LpeGdzd3e2aDDpcohq[mm2aX;uJIF{e2G7 MUfJcohq[mm2aX;uJI9nKGi3bXHuJGNRPjZvTVXMJINmdGxiZ4Lve5RpKGmwIHGgZ4VtdCC4aXHibYxqfHliYYPzZZktKEmFNUC9N|YvPTR7NzFOwG0> MnHWV2FPT0WU
CRO-AP2 cell NWTmVFViT3Kxd4ToJIlvcGmkaYTpc44h[XO|YYm= MVLJcohq[mm2aX;uJI9nKGi3bXHuJGNTVy2DUEKgZ4VtdCCpcn;3eIghcW5iYTDj[YxtKH[rYXLpcIl1gSCjc4PhfUwhUUN3ME2yMlM3ODh6IN88US=> M{nSVXNCVkeHUh?=
CTV-1 cell MmjIS5Jwf3SqIHnubIljcXSrb36gZZN{[Xl? MXPJcohq[mm2aX;uJI9nKGi3bXHuJGNVXi1zIHPlcIwh\3Kxd4ToJIlvKGFiY3XscEB3cWGkaXzpeJkh[XO|YYmsJGlEPTB;MkOuPVE1PSEQvF2= NH;uSpRUSU6JRWK=
Calu-6 cell NUnLbXFLT3Kxd4ToJIlvcGmkaYTpc44h[XO|YYm= Mn7pTY5pcWKrdHnvckBw\iCqdX3hckBE[Wy3LU[gZ4VtdCCpcn;3eIghcW5iYTDj[YxtKH[rYXLpcIl1gSCjc4PhfUwhUUN3ME20O{42QDZizszN M3vPbnNCVkeHUh?=
D-247MG cell NHrwXodIem:5dHigbY5pcWKrdHnvckBie3OjeR?= MnHpTY5pcWKrdHnvckBw\iCqdX3hckBFNTJ2N13HJINmdGxiZ4Lve5RpKGmwIHGgZ4VtdCC4aXHibYxqfHliYYPzZZktKEmFNUC9NE43OjhzNDFOwG0> MY\TRW5ITVJ?
D-263MG cell M{DWN2dzd3e2aDDpcohq[mm2aX;uJIF{e2G7 NHjyUHlKdmirYnn0bY9vKG:oIHj1cYFvKERvMk[zUWch[2WubDDndo94fGhiaX6gZUBk\WyuII\pZYJqdGm2eTDhd5NigSxiSVO1NF0xNjB6NUC5JO69VQ>? MYPTRW5ITVJ?
D-336MG cell Mn;WS5Jwf3SqIHnubIljcXSrb36gZZN{[Xl? MofITY5pcWKrdHnvckBw\iCqdX3hckBFNTN|Nl3HJINmdGxiZ4Lve5RpKGmwIHGgZ4VtdCC4aXHibYxqfHliYYPzZZktKEmFNUC9NE43Ojh3NDFOwG0> NIDq[|VUSU6JRWK=
D-392MG cell NF3GO49Iem:5dHigbY5pcWKrdHnvckBie3OjeR?= Mnz0TY5pcWKrdHnvckBw\iCqdX3hckBFNTN7Ml3HJINmdGxiZ4Lve5RpKGmwIHGgZ4VtdCC4aXHibYxqfHliYYPzZZktKEmFNUC9NU41OzB|OTFOwG0> MVTTRW5ITVJ?
D-502MG cell NWPhPWpyT3Kxd4ToJIlvcGmkaYTpc44h[XO|YYm= NWDKZoF5UW6qaXLpeIlwdiCxZjDoeY1idiCGLUWwNm1IKGOnbHyg[5Jwf3SqIHnuJIEh[2WubDD2bYFjcWyrdImgZZN{[XluIFnDOVA:QC53M{S5NkDPxE1? MlTRV2FPT0WU
D-542MG cell MXHHdo94fGhiaX7obYJqfGmxbjDhd5NigQ>? Moj4TY5pcWKrdHnvckBw\iCqdX3hckBFNTV2Ml3HJINmdGxiZ4Lve5RpKGmwIHGgZ4VtdCC4aXHibYxqfHliYYPzZZktKEmFNUC9NVIvOzF3MjFOwG0> MoK0V2FPT0WU
DB cell NYf1XotFT3Kxd4ToJIlvcGmkaYTpc44h[XO|YYm= MUjJcohq[mm2aX;uJI9nKGi3bXHuJGRDKGOnbHyg[5Jwf3SqIHnuJIEh[2WubDD2bYFjcWyrdImgZZN{[XluIFnDOVA:PDdwMUSxO{DPxE1? NETU[5dUSU6JRWK=
DEL cell M3rkS2dzd3e2aDDpcohq[mm2aX;uJIF{e2G7 NGfJPWpKdmirYnn0bY9vKG:oIHj1cYFvKESHTDDj[YxtKGe{b4f0bEBqdiCjIHPlcIwhfmmjYnnsbZR6KGG|c3H5MEBKSzVyPUeuNFE5QThizszN MnXhV2FPT0WU
DMS-114 cell NEjlSHRIem:5dHigbY5pcWKrdHnvckBie3OjeR?= NWiyTYZ3UW6qaXLpeIlwdiCxZjDoeY1idiCGTWOtNVE1KGOnbHyg[5Jwf3SqIHnuJIEh[2WubDD2bYFjcWyrdImgZZN{[XluIFnDOVA:PDlwOES2PEDPxE1? NWHvZpdZW0GQR1XS
DMS-153 cell NHTlbldIem:5dHigbY5pcWKrdHnvckBie3OjeR?= MWfJcohq[mm2aX;uJI9nKGi3bXHuJGROWy1zNUOgZ4VtdCCpcn;3eIghcW5iYTDj[YxtKH[rYXLpcIl1gSCjc4PhfUwhUUN3ME20Nk46QTJ|IN88US=> MXnTRW5ITVJ?
DOHH-2 cell NX;Lc2R2T3Kxd4ToJIlvcGmkaYTpc44h[XO|YYm= NIe0bFVKdmirYnn0bY9vKG:oIHj1cYFvKESRSFitNkBk\WyuIHfyc5d1cCCrbjDhJINmdGxidnnhZoltcXS7IHHzd4F6NCCLQ{WwQVQvOjJ5NkSg{txO NW\pZpBDW0GQR1XS
DSH1 cell M3W5PWdzd3e2aDDpcohq[mm2aX;uJIF{e2G7 M1PxO2lvcGmkaYTpc44hd2ZiaIXtZY4hTFOKMTDj[YxtKGe{b4f0bEBqdiCjIHPlcIwhfmmjYnnsbZR6KGG|c3H5MEBKSzVyPUiuOFM3OjNizszN NF3nZVZUSU6JRWK=
Daudi cell NH;hfXNIem:5dHigbY5pcWKrdHnvckBie3OjeR?= MmTsTY5pcWKrdHnvckBw\iCqdX3hckBF[XWmaTDj[YxtKGe{b4f0bEBqdiCjIHPlcIwhfmmjYnnsbZR6KGG|c3H5MEBKSzVyPUKuNFk5ODJizszN NXfsXnNFW0GQR1XS
EC-GI-10 cell NE\wSWFIem:5dHigbY5pcWKrdHnvckBie3OjeR?= NEnMXZpKdmirYnn0bY9vKG:oIHj1cYFvKEWFLVfJMVExKGOnbHyg[5Jwf3SqIHnuJIEh[2WubDD2bYFjcWyrdImgZZN{[XluIFnDOVA:PDRwMkW4PUDPxE1? NUDGWIljW0GQR1XS
ECC4 cell MofaS5Jwf3SqIHnubIljcXSrb36gZZN{[Xl? MmrmTY5pcWKrdHnvckBw\iCqdX3hckBGS0N2IHPlcIwh\3Kxd4ToJIlvKGFiY3XscEB3cWGkaXzpeJkh[XO|YYmsJGlEPTB;M{KuNVg6PiEQvF2= M2nqWHNCVkeHUh?=
EM-2 cell MX;Hdo94fGhiaX7obYJqfGmxbjDhd5NigQ>? NV\5e4lzUW6qaXLpeIlwdiCxZjDoeY1idiCHTT2yJINmdGxiZ4Lve5RpKGmwIHGgZ4VtdCC4aXHibYxqfHliYYPzZZktKEmFNUC9Nk41PTV7NDFOwG0> M2DNS3NCVkeHUh?=
ES1 cell M{jv[Gdzd3e2aDDpcohq[mm2aX;uJIF{e2G7 MoL2TY5pcWKrdHnvckBw\iCqdX3hckBGWzFiY3XscEBoem:5dHigbY4h[SClZXzsJJZq[WKrbHn0fUBie3OjeTygTWM2OD13LkW0NFg4KM7:TR?= Ml7jV2FPT0WU
ES3 cell MkHoS5Jwf3SqIHnubIljcXSrb36gZZN{[Xl? MYPJcohq[mm2aX;uJI9nKGi3bXHuJGVUOyClZXzsJIdzd3e2aDDpckBiKGOnbHygeoli[mmuaYT5JIF{e2G7LDDJR|UxRTR{LkS3Nlkh|ryP NF35[o9USU6JRWK=
ES4 cell MoDxS5Jwf3SqIHnubIljcXSrb36gZZN{[Xl? MkPoTY5pcWKrdHnvckBw\iCqdX3hckBGWzRiY3XscEBoem:5dHigbY4h[SClZXzsJJZq[WKrbHn0fUBie3OjeTygTWM2OD1|NT6xPVUh|ryP NX[w[Xl4W0GQR1XS
ES6 cell MU\Hdo94fGhiaX7obYJqfGmxbjDhd5NigQ>? NXL1cHRnUW6qaXLpeIlwdiCxZjDoeY1idiCHU{[gZ4VtdCCpcn;3eIghcW5iYTDj[YxtKH[rYXLpcIl1gSCjc4PhfUwhUUN3ME2wMlI1PzN|IN88US=> M1\iSXNCVkeHUh?=
ES7 cell NFHwSI1Iem:5dHigbY5pcWKrdHnvckBie3OjeR?= MonmTY5pcWKrdHnvckBw\iCqdX3hckBGWzdiY3XscEBoem:5dHigbY4h[SClZXzsJJZq[WKrbHn0fUBie3OjeTygTWM2OD13LkKzNVI1KM7:TR?= M3uycnNCVkeHUh?=
ES8 cell NEHPNWdIem:5dHigbY5pcWKrdHnvckBie3OjeR?= MofITY5pcWKrdHnvckBw\iCqdX3hckBGWzhiY3XscEBoem:5dHigbY4h[SClZXzsJJZq[WKrbHn0fUBie3OjeTygTWM2OD1yLkixPVI1KM7:TR?= MnvEV2FPT0WU
EW-18 cell M3zqXGdzd3e2aDDpcohq[mm2aX;uJIF{e2G7 Mn3YTY5pcWKrdHnvckBw\iCqdX3hckBGXy1zODDj[YxtKGe{b4f0bEBqdiCjIHPlcIwhfmmjYnnsbZR6KGG|c3H5MEBKSzVyPUGzMlY4PTlizszN NWC1R|dXW0GQR1XS
EW-22 cell Ml\oS5Jwf3SqIHnubIljcXSrb36gZZN{[Xl? MYjJcohq[mm2aX;uJI9nKGi3bXHuJGVYNTJ{IHPlcIwh\3Kxd4ToJIlvKGFiY3XscEB3cWGkaXzpeJkh[XO|YYmsJGlEPTB;NEeuO|k1PyEQvF2= M3;WW3NCVkeHUh?=
GCIY cell M{DFVWdzd3e2aDDpcohq[mm2aX;uJIF{e2G7 NVzOSmp7UW6qaXLpeIlwdiCxZjDoeY1idiCJQ1nZJINmdGxiZ4Lve5RpKGmwIHGgZ4VtdCC4aXHibYxqfHliYYPzZZktKEmFNUC9PU45ODN6OTFOwG0> NXm2dZJHW0GQR1XS
GDM-1 cell M1viOWdzd3e2aDDpcohq[mm2aX;uJIF{e2G7 MoDVTY5pcWKrdHnvckBw\iCqdX3hckBITE1vMTDj[YxtKGe{b4f0bEBqdiCjIHPlcIwhfmmjYnnsbZR6KGG|c3H5MEBKSzVyPUiuN|kyQTZizszN MnH1V2FPT0WU
GI-1 cell NGXuWWNIem:5dHigbY5pcWKrdHnvckBie3OjeR?= MX\Jcohq[mm2aX;uJI9nKGi3bXHuJGdKNTFiY3XscEBoem:5dHigbY4h[SClZXzsJJZq[WKrbHn0fUBie3OjeTygTWM2OD1yLkCwOVI{KM7:TR?= MnHzV2FPT0WU
GI-ME-N cell MWPHdo94fGhiaX7obYJqfGmxbjDhd5NigQ>? MmnsTY5pcWKrdHnvckBw\iCqdX3hckBIUS2PRT3OJINmdGxiZ4Lve5RpKGmwIHGgZ4VtdCC4aXHibYxqfHliYYPzZZktKEmFNUC9NE4xPDl3MTFOwG0> M{K0b3NCVkeHUh?=
GR-ST cell MWXHdo94fGhiaX7obYJqfGmxbjDhd5NigQ>? NIf4ZY5KdmirYnn0bY9vKG:oIHj1cYFvKEeULWPUJINmdGxiZ4Lve5RpKGmwIHGgZ4VtdCC4aXHibYxqfHliYYPzZZktKEmFNUC9NVMvPzlyMjFOwG0> M4DlcXNCVkeHUh?=
GT3TKB cell MWXHdo94fGhiaX7obYJqfGmxbjDhd5NigQ>? Ml33TY5pcWKrdHnvckBw\iCqdX3hckBIXDOWS1KgZ4VtdCCpcn;3eIghcW5iYTDj[YxtKH[rYXLpcIl1gSCjc4PhfUwhUUN3ME2xMlYxOzh7IN88US=> M{DMdXNCVkeHUh?=
HAL-01 cell M2PQdGdzd3e2aDDpcohq[mm2aX;uJIF{e2G7 M{nyTmlvcGmkaYTpc44hd2ZiaIXtZY4hUEGOLUCxJINmdGxiZ4Lve5RpKGmwIHGgZ4VtdCC4aXHibYxqfHliYYPzZZktKEmFNUC9Ok43QTdzMjFOwG0> NH7MVVlUSU6JRWK=
HCC1599 cell MnnBS5Jwf3SqIHnubIljcXSrb36gZZN{[Xl? NIrH[oVKdmirYnn0bY9vKG:oIHj1cYFvKEiFQ{G1PVkh[2WubDDndo94fGhiaX6gZUBk\WyuII\pZYJqdGm2eTDhd5NigSxiSVO1NF0{Py54MEGxJO69VQ>? Mn\MV2FPT0WU
HCC2218 cell NHj0RpZIem:5dHigbY5pcWKrdHnvckBie3OjeR?= MlGwTY5pcWKrdHnvckBw\iCqdX3hckBJS0N{MkG4JINmdGxiZ4Lve5RpKGmwIHGgZ4VtdCC4aXHibYxqfHliYYPzZZktKEmFNUC9NVMvOzh|NDFOwG0> MXHTRW5ITVJ?
HD-MY-Z cell Mn\rS5Jwf3SqIHnubIljcXSrb36gZZN{[Xl? MXPJcohq[mm2aX;uJI9nKGi3bXHuJGhFNU2\LWqgZ4VtdCCpcn;3eIghcW5iYTDj[YxtKH[rYXLpcIl1gSCjc4PhfUwhUUN3ME2yOU4zOTR4IN88US=> NIT4VFZUSU6JRWK=
HL-60 cell NUS3cIZCT3Kxd4ToJIlvcGmkaYTpc44h[XO|YYm= MW\Jcohq[mm2aX;uJI9nKGi3bXHuJGhNNTZyIHPlcIwh\3Kxd4ToJIlvKGFiY3XscEB3cWGkaXzpeJkh[XO|YYmsJGlEPTB;MUKuNlEyPCEQvF2= MoP6V2FPT0WU
HOP-62 cell MmfGS5Jwf3SqIHnubIljcXSrb36gZZN{[Xl? NU\JVGk5UW6qaXLpeIlwdiCxZjDoeY1idiCKT2CtOlIh[2WubDDndo94fGhiaX6gZUBk\WyuII\pZYJqdGm2eTDhd5NigSxiSVO1NF0zOy57NUK3JO69VQ>? M2XTNHNCVkeHUh?=
HT cell NGfEXI9Iem:5dHigbY5pcWKrdHnvckBie3OjeR?= NFW3XodKdmirYnn0bY9vKG:oIHj1cYFvKEiWIHPlcIwh\3Kxd4ToJIlvKGFiY3XscEB3cWGkaXzpeJkh[XO|YYmsJGlEPTB;ND60OFMzOSEQvF2= NXvCU4pwW0GQR1XS
HT-144 cell MlfUS5Jwf3SqIHnubIljcXSrb36gZZN{[Xl? MnHMTY5pcWKrdHnvckBw\iCqdX3hckBJXC1zNESgZ4VtdCCpcn;3eIghcW5iYTDj[YxtKH[rYXLpcIl1gSCjc4PhfUwhUUN3ME20MlkxPjh4IN88US=> M1S0dXNCVkeHUh?=
HUTU-80 cell M4HwNWdzd3e2aDDpcohq[mm2aX;uJIF{e2G7 NID0bVNKdmirYnn0bY9vKG:oIHj1cYFvKEiXVGWtPFAh[2WubDDndo94fGhiaX6gZUBk\WyuII\pZYJqdGm2eTDhd5NigSxiSVO1NF0{Njd6OUi2JO69VQ>? MWnTRW5ITVJ?
IST-MEL1 cell M37ocmdzd3e2aDDpcohq[mm2aX;uJIF{e2G7 NX3zSWJFUW6qaXLpeIlwdiCxZjDoeY1idiCLU2StUWVNOSClZXzsJIdzd3e2aDDpckBiKGOnbHygeoli[mmuaYT5JIF{e2G7LDDJR|UxRTN{LkmwPFYh|ryP NV3WTnZnW0GQR1XS
IST-SL1 cell MXnHdo94fGhiaX7obYJqfGmxbjDhd5NigQ>? MWTJcohq[mm2aX;uJI9nKGi3bXHuJGlUXC2VTEGgZ4VtdCCpcn;3eIghcW5iYTDj[YxtKH[rYXLpcIl1gSCjc4PhfUwhUUN3ME2yMlE4ODd7IN88US=> MoLsV2FPT0WU
IST-SL2 cell M332emdzd3e2aDDpcohq[mm2aX;uJIF{e2G7 NWfDNZVwUW6qaXLpeIlwdiCxZjDoeY1idiCLU2StV2wzKGOnbHyg[5Jwf3SqIHnuJIEh[2WubDD2bYFjcWyrdImgZZN{[XluIFnDOVA:Oy5{Nk[wPEDPxE1? Mk\mV2FPT0WU
K052 cell MXLHdo94fGhiaX7obYJqfGmxbjDhd5NigQ>? MmS5TY5pcWKrdHnvckBw\iCqdX3hckBMODV{IHPlcIwh\3Kxd4ToJIlvKGFiY3XscEB3cWGkaXzpeJkh[XO|YYmsJGlEPTB;MD63OVMxOSEQvF2= MmDuV2FPT0WU
K5 cell NV\GT2ZMT3Kxd4ToJIlvcGmkaYTpc44h[XO|YYm= M{XaTmlvcGmkaYTpc44hd2ZiaIXtZY4hUzViY3XscEBoem:5dHigbY4h[SClZXzsJJZq[WKrbHn0fUBie3OjeTygTWM2OD1|Mz61PVE2KM7:TR?= Mn7YV2FPT0WU
KALS-1 cell M2n3cWdzd3e2aDDpcohq[mm2aX;uJIF{e2G7 MVHJcohq[mm2aX;uJI9nKGi3bXHuJGtCVFNvMTDj[YxtKGe{b4f0bEBqdiCjIHPlcIwhfmmjYnnsbZR6KGG|c3H5MEBKSzVyPUK5MlM6PjlizszN Ml7OV2FPT0WU
KARPAS-422 cell MYfHdo94fGhiaX7obYJqfGmxbjDhd5NigQ>? MULJcohq[mm2aX;uJI9nKGi3bXHuJGtCWlCDUz20NlIh[2WubDDndo94fGhiaX6gZUBk\WyuII\pZYJqdGm2eTDhd5NigSxiSVO1NF01Oi57MUSyJO69VQ>? NHX2bWtUSU6JRWK=
KARPAS-45 cell Mli3S5Jwf3SqIHnubIljcXSrb36gZZN{[Xl? NXjGdVk2UW6qaXLpeIlwdiCxZjDoeY1idiCNQWLQRXMuPDViY3XscEBoem:5dHigbY4h[SClZXzsJJZq[WKrbHn0fUBie3OjeTygTWM2OD12LkGxNlQ4KM7:TR?= M1TxOXNCVkeHUh?=
KE-37 cell M17XV2dzd3e2aDDpcohq[mm2aX;uJIF{e2G7 MkLhTY5pcWKrdHnvckBw\iCqdX3hckBMTS1|NzDj[YxtKGe{b4f0bEBqdiCjIHPlcIwhfmmjYnnsbZR6KGG|c3H5MEBKSzVyPUmuPFM2KM7:TR?= NWDjN4ppW0GQR1XS
KG-1 cell NXfwUo1YT3Kxd4ToJIlvcGmkaYTpc44h[XO|YYm= M1fRNGlvcGmkaYTpc44hd2ZiaIXtZY4hU0dvMTDj[YxtKGe{b4f0bEBqdiCjIHPlcIwhfmmjYnnsbZR6KGG|c3H5MEBKSzVyPUKzMlk4PTdizszN NWf5c|FwW0GQR1XS
KGN cell MV7Hdo94fGhiaX7obYJqfGmxbjDhd5NigQ>? NIn2T3FKdmirYnn0bY9vKG:oIHj1cYFvKEuJTjDj[YxtKGe{b4f0bEBqdiCjIHPlcIwhfmmjYnnsbZR6KGG|c3H5MEBKSzVyPUCuOVY4PDJizszN MUPTRW5ITVJ?
KM12 cell M{\HeGdzd3e2aDDpcohq[mm2aX;uJIF{e2G7 MlOyTY5pcWKrdHnvckBw\iCqdX3hckBMVTF{IHPlcIwh\3Kxd4ToJIlvKGFiY3XscEB3cWGkaXzpeJkh[XO|YYmsJGlEPTB;Mz61Nlk3PCEQvF2= MlnvV2FPT0WU
KMOE-2 cell NIH6U5pIem:5dHigbY5pcWKrdHnvckBie3OjeR?= NW\mdnpVUW6qaXLpeIlwdiCxZjDoeY1idiCNTV;FMVIh[2WubDDndo94fGhiaX6gZUBk\WyuII\pZYJqdGm2eTDhd5NigSxiSVO1NF0{OC52NUS5JO69VQ>? MoD2V2FPT0WU
KNS-42 cell M2O3Xmdzd3e2aDDpcohq[mm2aX;uJIF{e2G7 M{TtdWlvcGmkaYTpc44hd2ZiaIXtZY4hU06VLUSyJINmdGxiZ4Lve5RpKGmwIHGgZ4VtdCC4aXHibYxqfHliYYPzZZktKEmFNUC9PE45OTlzNTFOwG0> MUXTRW5ITVJ?
KNS-81-FD cell NYPQb5pQT3Kxd4ToJIlvcGmkaYTpc44h[XO|YYm= MWHJcohq[mm2aX;uJI9nKGi3bXHuJGtPWy16MT3GSEBk\WyuIHfyc5d1cCCrbjDhJINmdGxidnnhZoltcXS7IHHzd4F6NCCLQ{WwQVM4NjR{NjFOwG0> NGrmXYFUSU6JRWK=
KS-1 cell MkjrS5Jwf3SqIHnubIljcXSrb36gZZN{[Xl? NUizWpBLUW6qaXLpeIlwdiCxZjDoeY1idiCNUz2xJINmdGxiZ4Lve5RpKGmwIHGgZ4VtdCC4aXHibYxqfHliYYPzZZktKEmFNUC9NE4xODR4IN88US=> M4C5N3NCVkeHUh?=
KU812 cell M4TPcWdzd3e2aDDpcohq[mm2aX;uJIF{e2G7 MYjJcohq[mm2aX;uJI9nKGi3bXHuJGtWQDF{IHPlcIwh\3Kxd4ToJIlvKGFiY3XscEB3cWGkaXzpeJkh[XO|YYmsJGlEPTB;MkOuOFg1KM7:TR?= NXW0VpJ5W0GQR1XS
L-540 cell NVvPXFlDT3Kxd4ToJIlvcGmkaYTpc44h[XO|YYm= NULoPZJIUW6qaXLpeIlwdiCxZjDoeY1idiCOLUW0NEBk\WyuIHfyc5d1cCCrbjDhJINmdGxidnnhZoltcXS7IHHzd4F6NCCLQ{WwQVIxNjd2NEWg{txO NIm2c4tUSU6JRWK=
LAMA-84 cell NYn0dZpkT3Kxd4ToJIlvcGmkaYTpc44h[XO|YYm= MX;Jcohq[mm2aX;uJI9nKGi3bXHuJGxCVUFvOESgZ4VtdCCpcn;3eIghcW5iYTDj[YxtKH[rYXLpcIl1gSCjc4PhfUwhUUN3ME2xN{43PzR{IN88US=> NV\EbHR5W0GQR1XS
LB1047-RCC cell NYfQTGs2T3Kxd4ToJIlvcGmkaYTpc44h[XO|YYm= NIfnXnpKdmirYnn0bY9vKG:oIHj1cYFvKEyEMUC0O{1TS0NiY3XscEBoem:5dHigbY4h[SClZXzsJJZq[WKrbHn0fUBie3OjeTygTWM2OD1{OD6zPFg{KM7:TR?= NIqyXYZUSU6JRWK=
LB2241-RCC cell MVvHdo94fGhiaX7obYJqfGmxbjDhd5NigQ>? NUDCNJY{UW6qaXLpeIlwdiCxZjDoeY1idiCOQkKyOFEuWkOFIHPlcIwh\3Kxd4ToJIlvKGFiY3XscEB3cWGkaXzpeJkh[XO|YYmsJGlEPTB;MUCuOVU{PiEQvF2= MWXTRW5ITVJ?
LB2518-MEL cell NG\DSolIem:5dHigbY5pcWKrdHnvckBie3OjeR?= NFfROWFKdmirYnn0bY9vKG:oIHj1cYFvKEyEMkWxPE1OTUxiY3XscEBoem:5dHigbY4h[SClZXzsJJZq[WKrbHn0fUBie3OjeTygTWM2OD1zLkexOFk3|ryP Mki2V2FPT0WU
LB831-BLC cell NXzNXoJNT3Kxd4ToJIlvcGmkaYTpc44h[XO|YYm= NUHlT|ZrUW6qaXLpeIlwdiCxZjDoeY1idiCOQkizNU1DVENiY3XscEBoem:5dHigbY4h[SClZXzsJJZq[WKrbHn0fUBie3OjeTygTWM2OD1zMT6xO|I3KM7:TR?= NIezZmxUSU6JRWK=
LB996-RCC cell MXjHdo94fGhiaX7obYJqfGmxbjDhd5NigQ>? MYXJcohq[mm2aX;uJI9nKGi3bXHuJGxDQTl4LWLDR{Bk\WyuIHfyc5d1cCCrbjDhJINmdGxidnnhZoltcXS7IHHzd4F6NCCLQ{WwQVEzNjd2M{Gg{txO M4PZSXNCVkeHUh?=
LC4-1 cell Mn3US5Jwf3SqIHnubIljcXSrb36gZZN{[Xl? MlvsTY5pcWKrdHnvckBw\iCqdX3hckBNSzRvMTDj[YxtKGe{b4f0bEBqdiCjIHPlcIwhfmmjYnnsbZR6KGG|c3H5MEBKSzVyPUOyMlg{PDFizszN NFftSoRUSU6JRWK=
LOUCY cell MULHdo94fGhiaX7obYJqfGmxbjDhd5NigQ>? MYjJcohq[mm2aX;uJI9nKGi3bXHuJGxQXUO\IHPlcIwh\3Kxd4ToJIlvKGFiY3XscEB3cWGkaXzpeJkh[XO|YYmsJGlEPTB;MT6xOVI4PiEQvF2= Mmm5V2FPT0WU
LOXIMVI cell MnHTS5Jwf3SqIHnubIljcXSrb36gZZN{[Xl? M33FVGlvcGmkaYTpc44hd2ZiaIXtZY4hVE:[SV3WTUBk\WyuIHfyc5d1cCCrbjDhJINmdGxidnnhZoltcXS7IHHzd4F6NCCLQ{WwQVMxNjJzMkKg{txO MoXJV2FPT0WU
LS-123 cell Ml7RS5Jwf3SqIHnubIljcXSrb36gZZN{[Xl? M{C0OWlvcGmkaYTpc44hd2ZiaIXtZY4hVFNvMUKzJINmdGxiZ4Lve5RpKGmwIHGgZ4VtdCC4aXHibYxqfHliYYPzZZktKEmFNUC9N|kvOjJ3ODFOwG0> NWHSOVB[W0GQR1XS
LU-134-A cell NX:5c5dlT3Kxd4ToJIlvcGmkaYTpc44h[XO|YYm= Ml36TY5pcWKrdHnvckBw\iCqdX3hckBNXS1zM{StRUBk\WyuIHfyc5d1cCCrbjDhJINmdGxidnnhZoltcXS7IHHzd4F6NCCLQ{WwQVcvOTRyNkig{txO M1XnfHNCVkeHUh?=
LU-139 cell MULHdo94fGhiaX7obYJqfGmxbjDhd5NigQ>? NWe1T2NMUW6qaXLpeIlwdiCxZjDoeY1idiCOVT2xN|kh[2WubDDndo94fGhiaX6gZUBk\WyuII\pZYJqdGm2eTDhd5NigSxiSVO1NF0zOi5{MUig{txO MmLOV2FPT0WU
LXF-289 cell M1PVSGdzd3e2aDDpcohq[mm2aX;uJIF{e2G7 M3nGOWlvcGmkaYTpc44hd2ZiaIXtZY4hVFiILUK4PUBk\WyuIHfyc5d1cCCrbjDhJINmdGxidnnhZoltcXS7IHHzd4F6NCCLQ{WwQVE4NjR|NUJOwG0> MVrTRW5ITVJ?
MC116 cell M4qwdGdzd3e2aDDpcohq[mm2aX;uJIF{e2G7 MW\Jcohq[mm2aX;uJI9nKGi3bXHuJG1EOTF4IHPlcIwh\3Kxd4ToJIlvKGFiY3XscEB3cWGkaXzpeJkh[XO|YYmsJGlEPTB;NEWuNFg1OSEQvF2= MWPTRW5ITVJ?
MDA-MB-134-VI cell NVLDTldGT3Kxd4ToJIlvcGmkaYTpc44h[XO|YYm= NUDvUlN1UW6qaXLpeIlwdiCxZjDoeY1idiCPRFGtUWIuOTN2LW\JJINmdGxiZ4Lve5RpKGmwIHGgZ4VtdCC4aXHibYxqfHliYYPzZZktKEmFNUC9N|kvOjR6NjFOwG0> MlvJV2FPT0WU
MFH-ino cell MoHpS5Jwf3SqIHnubIljcXSrb36gZZN{[Xl? MUjJcohq[mm2aX;uJI9nKGi3bXHuJG1HUC2rbn:gZ4VtdCCpcn;3eIghcW5iYTDj[YxtKH[rYXLpcIl1gSCjc4PhfUwhUUN3ME2wMlY1Ozh|IN88US=> M{Lvc3NCVkeHUh?=
MHH-NB-11 cell MXHHdo94fGhiaX7obYJqfGmxbjDhd5NigQ>? NGOydXBKdmirYnn0bY9vKG:oIHj1cYFvKE2KSD3ORk0yOSClZXzsJIdzd3e2aDDpckBiKGOnbHygeoli[mmuaYT5JIF{e2G7LDDJR|UxRTBwME[2PUDPxE1? MX7TRW5ITVJ?
ML-2 cell M4Hl[Gdzd3e2aDDpcohq[mm2aX;uJIF{e2G7 Mn7PTY5pcWKrdHnvckBw\iCqdX3hckBOVC1{IHPlcIwh\3Kxd4ToJIlvKGFiY3XscEB3cWGkaXzpeJkh[XO|YYmsJGlEPTB;Mz60NFMxPCEQvF2= NV3kOlVjW0GQR1XS
MOLT-13 cell NF7CT2RIem:5dHigbY5pcWKrdHnvckBie3OjeR?= M1zRS2lvcGmkaYTpc44hd2ZiaIXtZY4hVU:OVD2xN{Bk\WyuIHfyc5d1cCCrbjDhJINmdGxidnnhZoltcXS7IHHzd4F6NCCLQ{WwQVQvPDN4NUOg{txO NY\3VXRKW0GQR1XS
MOLT-16 cell NXTtSo1iT3Kxd4ToJIlvcGmkaYTpc44h[XO|YYm= M{XqS2lvcGmkaYTpc44hd2ZiaIXtZY4hVU:OVD2xOkBk\WyuIHfyc5d1cCCrbjDhJINmdGxidnnhZoltcXS7IHHzd4F6NCCLQ{WwQVQvOTFzNkOg{txO MYfTRW5ITVJ?
MOLT-4 cell MXvHdo94fGhiaX7obYJqfGmxbjDhd5NigQ>? MYHJcohq[mm2aX;uJI9nKGi3bXHuJG1QVFRvNDDj[YxtKGe{b4f0bEBqdiCjIHPlcIwhfmmjYnnsbZR6KGG|c3H5MEBKSzVyPUG0MlQyOjRizszN MUTTRW5ITVJ?
MPP-89 cell MVXHdo94fGhiaX7obYJqfGmxbjDhd5NigQ>? NUTXT4Q4UW6qaXLpeIlwdiCxZjDoeY1idiCPUGCtPFkh[2WubDDndo94fGhiaX6gZUBk\WyuII\pZYJqdGm2eTDhd5NigSxiSVO1NF0yNjJ3OUKyJO69VQ>? M{j4OnNCVkeHUh?=
MRK-nu-1 cell NWX3WFAzT3Kxd4ToJIlvcGmkaYTpc44h[XO|YYm= NUHzUWFWUW6qaXLpeIlwdiCxZjDoeY1idiCPUlutcpUuOSClZXzsJIdzd3e2aDDpckBiKGOnbHygeoli[mmuaYT5JIF{e2G7LDDJR|UxRTBwNUe1O|Ih|ryP NGrCWnVUSU6JRWK=
MSTO-211H cell NHjzcodIem:5dHigbY5pcWKrdHnvckBie3OjeR?= MmTuTY5pcWKrdHnvckBw\iCqdX3hckBOW1SRLUKxNWgh[2WubDDndo94fGhiaX6gZUBk\WyuII\pZYJqdGm2eTDhd5NigSxiSVO1NF0yOi56Nkmg{txO MoXBV2FPT0WU
MV-4-11 cell Ml7uS5Jwf3SqIHnubIljcXSrb36gZZN{[Xl? MX\Jcohq[mm2aX;uJI9nKGi3bXHuJG1XNTRvMUGgZ4VtdCCpcn;3eIghcW5iYTDj[YxtKH[rYXLpcIl1gSCjc4PhfUwhUUN3ME2wMlE{QTF3IN88US=> NG\ZempUSU6JRWK=
NALM-6 cell M4PQcGdzd3e2aDDpcohq[mm2aX;uJIF{e2G7 M1PvPGlvcGmkaYTpc44hd2ZiaIXtZY4hVkGOTT22JINmdGxiZ4Lve5RpKGmwIHGgZ4VtdCC4aXHibYxqfHliYYPzZZktKEmFNUC9NU42PjFyOTFOwG0> NXrHOmtOW0GQR1XS
NB1 cell NGSzTJFIem:5dHigbY5pcWKrdHnvckBie3OjeR?= M{\j[2lvcGmkaYTpc44hd2ZiaIXtZY4hVkJzIHPlcIwh\3Kxd4ToJIlvKGFiY3XscEB3cWGkaXzpeJkh[XO|YYmsJGlEPTB;Mz64OFM3QSEQvF2= MXnTRW5ITVJ?
NB10 cell MkTPS5Jwf3SqIHnubIljcXSrb36gZZN{[Xl? MnKzTY5pcWKrdHnvckBw\iCqdX3hckBPSjFyIHPlcIwh\3Kxd4ToJIlvKGFiY3XscEB3cWGkaXzpeJkh[XO|YYmsJGlEPTB;MD6xN|kyPSEQvF2= NXnuO5pwW0GQR1XS
NB12 cell MlX4S5Jwf3SqIHnubIljcXSrb36gZZN{[Xl? M4jiXWlvcGmkaYTpc44hd2ZiaIXtZY4hVkJzMjDj[YxtKGe{b4f0bEBqdiCjIHPlcIwhfmmjYnnsbZR6KGG|c3H5MEBKSzVyPUG2MlU3PTZizszN NH;YbXZUSU6JRWK=
NB13 cell MoD5S5Jwf3SqIHnubIljcXSrb36gZZN{[Xl? M2TUNGlvcGmkaYTpc44hd2ZiaIXtZY4hVkJzMzDj[YxtKGe{b4f0bEBqdiCjIHPlcIwhfmmjYnnsbZR6KGG|c3H5MEBKSzVyPUKuN|EzPzhizszN MYPTRW5ITVJ?
NB17 cell NIfWOWdIem:5dHigbY5pcWKrdHnvckBie3OjeR?= MmrtTY5pcWKrdHnvckBw\iCqdX3hckBPSjF5IHPlcIwh\3Kxd4ToJIlvKGFiY3XscEB3cWGkaXzpeJkh[XO|YYmsJGlEPTB;Mz61PFA2OSEQvF2= MnfBV2FPT0WU
NB6 cell M{\oTGdzd3e2aDDpcohq[mm2aX;uJIF{e2G7 NXT2TVg3UW6qaXLpeIlwdiCxZjDoeY1idiCQQk[gZ4VtdCCpcn;3eIghcW5iYTDj[YxtKH[rYXLpcIl1gSCjc4PhfUwhUUN3ME2wMlU6OTF2IN88US=> NWf3[W9bW0GQR1XS
NCCIT cell NVrV[FlbT3Kxd4ToJIlvcGmkaYTpc44h[XO|YYm= MkPqTY5pcWKrdHnvckBw\iCqdX3hckBPS0OLVDDj[YxtKGe{b4f0bEBqdiCjIHPlcIwhfmmjYnnsbZR6KGG|c3H5MEBKSzVyPUSxMlg1PTNizszN NHL1OnVUSU6JRWK=
NCI-H1155 cell M3njcmdzd3e2aDDpcohq[mm2aX;uJIF{e2G7 NYS5WXBNUW6qaXLpeIlwdiCxZjDoeY1idiCQQ1mtTFEyPTViY3XscEBoem:5dHigbY4h[SClZXzsJJZq[WKrbHn0fUBie3OjeTygTWM2OD1zND6zOFA5KM7:TR?= NVPrdJFTW0GQR1XS
NCI-H1304 cell MVTHdo94fGhiaX7obYJqfGmxbjDhd5NigQ>? NXTjOoI3UW6qaXLpeIlwdiCxZjDoeY1idiCQQ1mtTFE{ODRiY3XscEBoem:5dHigbY4h[SClZXzsJJZq[WKrbHn0fUBie3OjeTygTWM2OD1zMT64PVgzKM7:TR?= M{nTdXNCVkeHUh?=
NCI-H1355 cell MkjIS5Jwf3SqIHnubIljcXSrb36gZZN{[Xl? M123fmlvcGmkaYTpc44hd2ZiaIXtZY4hVkOLLVixN|U2KGOnbHyg[5Jwf3SqIHnuJIEh[2WubDD2bYFjcWyrdImgZZN{[XluIFnDOVA:PC57NEGxJO69VQ>? MXnTRW5ITVJ?
NCI-H1395 cell MVTHdo94fGhiaX7obYJqfGmxbjDhd5NigQ>? NFG3NZdKdmirYnn0bY9vKG:oIHj1cYFvKE6FST3INVM6PSClZXzsJIdzd3e2aDDpckBiKGOnbHygeoli[mmuaYT5JIF{e2G7LDDJR|UxRTJ{Lki3PVUh|ryP NVK2XFdNW0GQR1XS
NCI-H1417 cell NF7jWWpIem:5dHigbY5pcWKrdHnvckBie3OjeR?= MWPJcohq[mm2aX;uJI9nKGi3bXHuJG5EUS2KMUSxO{Bk\WyuIHfyc5d1cCCrbjDhJINmdGxidnnhZoltcXS7IHHzd4F6NCCLQ{WwQVUvPjd3MkKg{txO M4jJTnNCVkeHUh?=
NCI-H1436 cell NFW2OpBIem:5dHigbY5pcWKrdHnvckBie3OjeR?= NWfyeIJ1UW6qaXLpeIlwdiCxZjDoeY1idiCQQ1mtTFE1OzZiY3XscEBoem:5dHigbY4h[SClZXzsJJZq[WKrbHn0fUBie3OjeTygTWM2OD1|Lki0NVAyKM7:TR?= NEjhV|NUSU6JRWK=
NTERA-S-cl-D1 cell MUDHdo94fGhiaX7obYJqfGmxbjDhd5NigQ>? NWnrNlNwUW6qaXLpeIlwdiCxZjDoeY1idiCQVFXSRU1UNWOuLVSxJINmdGxiZ4Lve5RpKGmwIHGgZ4VtdCC4aXHibYxqfHliYYPzZZktKEmFNUC9NVIvQDl|NTFOwG0> NHrHbVNUSU6JRWK=
JiyoyeP-2003 cell M4H1W2dzd3e2aDDpcohq[mm2aX;uJIF{e2G7 MWXJcohq[mm2aX;uJI9nKGi3bXHuJGpqgW:7ZWCtNlAxOyClZXzsJIdzd3e2aDDpckBiKGOnbHygeoli[mmuaYT5JIF{e2G7LDDJR|UxRTN4Lk[yPFQh|ryP NWjwfoJ1W0GQR1XS

... Click to View More Cell Line Experimental Data

In vivo Oral administration of GSK269962A produced a profound dose-dependent reduction of systemic blood pressure in spontaneously hypertensive rats. The reduction of blood pressure was acute and substantial. The maximal effect on blood pressure was observed approximately 2 h after oral gavages. The reduction of blood pressure was accompanied by an acute, dose-dependent increase in heart rate, presumably due to the activation of baroreflex mechanism[1]. ROCK inhibition with the use of GSK 269962 in the 10 mg/kg dose, in turn, triggered an increase in VV(voided volume), PVR(post-void residual), VT(volume threshold), VE(voiding efficiency), ICI(intercontraction interval), BC(bladder compliance), and VTNVC(volume threshold to elicit NVC). The inhibition of the ROCK pathway through GSK 269962 appeared to have no effect on either HR(heart rate), SBP(systolic blood pressure), MBP(systolic blood pressure), or DBP(diastolic blood pressure)[2]. NVC:nonvoiding contractions.

Protocol

Cell Research:[1]
+ Expand
  • Cell lines: Human primary smooth muscle cells
  • Concentrations: 3 μM
  • Incubation Time: 150 min
  • Method: Human primary smooth muscle cells were serum-starved(cells were grown on coverslips, and at approximately 50% confluence, they were serum-starved overnight) and stimulated with AngII (100 nM) for 2 h. ROCK inhibitors (3 μM for SB-772077-B or GSK269962A) were added 30 min before AngII stimulation, and cells were fixed and stained with rhodamine phalloidin. Confocal images of actin stain were obtained.
    (Only for Reference)
Animal Research:[2]
+ Expand
  • Animal Models: female Wistar rats
  • Formulation: saline
  • Dosages: 5 or 10 mg/kg
  • Administration: intra-arterially
    (Only for Reference)

Solubility (25°C)

In vitro DMSO 100 mg/mL (164.72 mM)
Ethanol 6 mg/mL (9.88 mM)
Water Insoluble

* Please note that Selleck tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.

Chemical Information

Molecular Weight 607.06
Formula

C29H30N8O5.HCl

CAS No. 850664-21-0(free base)
Storage powder
Synonyms GSK269962A, GSK269962B

Bio Calculators

Molarity Calculator

Molarity Calculator

Calculate the mass, volume or concentration required for a solution. The Selleck molarity calculator is based on the following equation:

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

  • Mass
    Concentration
    Volume
    Molecular Weight

*When preparing stock solutions, please always use the batch-specific molecular weight of the product found on the via label and MSDS / COA (available on product pages).

Dilution Calculator

Dilution Calculator

Calculate the dilution required to prepare a stock solution. The Selleck dilution calculator is based on the following equation:

Concentration (start) x Volume (start) = Concentration (final) x Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2 ( Input Output )

  • C1
    V1
    C2
    V2

* When preparing stock solutions always use the batch-specific molecular weight of the product found on the vial label and MSDS / COA (available online).

The Serial Dilution Calculator Equation

  • Serial Dilutions

  • Computed Result

  • C1=C0/X C1: LOG(C1):
    C2=C1/X C2: LOG(C2):
    C3=C2/X C3: LOG(C3):
    C4=C3/X C4: LOG(C4):
    C5=C4/X C5: LOG(C5):
    C6=C5/X C6: LOG(C6):
    C7=C6/X C7: LOG(C7):
    C8=C7/X C8: LOG(C8):
Molecular Weight Calculator

Molecular Weight Calculator

Enter the chemical formula of a compound to calculate its molar mass and elemental composition:

Total Molecular Weight: g/mol

Tip: Chemical formula is case sensitive. C10H16N2O2 c10h16n2o2

Instructions to calculate molar mass (molecular weight) of a chemical compound:

To calculate molar mass of a chemical compound, please enter its chemical formula and click 'Calculate'.

Definitions of molecular mass, molecular weight, molar mass and molar weight:

Molecular mass (molecular weight) is the mass of one molecule of a substance and is expressed in the unified atomic mass units (u). (1 u is equal to 1/12 the mass of one atom of carbon-12)
Molar mass (molar weight) is the mass of one mole of a substance and is expressed in g/mol.

Molarity Calculator

Mass Concentration Volume Molecular Weight

Tech Support

Answers to questions you may have can be found in the inhibitor handling instructions. Topics include how to prepare stock solutions, how to store inhibitors, and issues that need special attention for cell-based assays and animal experiments.

Handling Instructions

Tel: +1-832-582-8158 Ext:3

If you have any other enquiries, please leave a message.

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ROCK Signaling Pathway Map

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Cell Lines Assay Type Concentration Incubation Time Formulation Activity Description PMID