GSK269962A HCl

Catalog No.S7687 Synonyms: GSK269962B, GSK269962, GSK 269962

GSK269962A HCl Chemical Structure

Molecular Weight(MW): 607.06

GSK269962 is a selective ROCK(Rho-associated protein kinase) inhibitor with IC50 values of 1.6 and 4 nM for ROCK1 and ROCK2, respectively.

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Purity & Quality Control

Choose Selective ROCK Inhibitors

Biological Activity

Description GSK269962 is a selective ROCK(Rho-associated protein kinase) inhibitor with IC50 values of 1.6 and 4 nM for ROCK1 and ROCK2, respectively.
Targets
ROCK1 [1]
(Cell-free assay)
ROCK2 [1]
(Cell-free assay)
MSK1 [1]
(Cell-free assay)
RSK1 [1]
(Cell-free assay)
1.6 nM 4 nM 49 nM 132 nM
In vitro

GSK269962A completely abolished the actin stress fiber formation induced by angiotensin II in human smooth muscles. Such suppressive effect on actin fiber formation was observed beginning at around 1 μM GSK269962A. GSK269962A induced vasorelaxation in preconstricted rat aorta(tissue baths) with an IC50 of 35 nM. the relaxation induced by GSK269962A is reversible. GSK269962A suppressed IL-6 mRNA transcription and reduced LPS-induced IL-6 and TNF-α protein production in macrophages[1].

Cell Data
Cell Lines Assay Type Concentration Incubation Time Formulation Activity Description PMID
NCI-H1581 NFuzPI1Iem:5dHigbY5pcWKrdHnvckBie3OjeR?= MoHSTY5pcWKrdHnvckBw\iCqdX3hckBPS0lvSEG1PFEh[2WubDDndo94fGhiaX6gZUBk\WyuII\pZYJqdGm2eTDhd5NigSxiSVO1NF0yQC56NEe3JO69VQ>? M{\VVHNCVkeHUh?=
NCI-H1694 NVzB[Hl2T3Kxd4ToJIlvcGmkaYTpc44h[XO|YYm= MXHJcohq[mm2aX;uJI9nKGi3bXHuJG5EUS2KMU[5OEBk\WyuIHfyc5d1cCCrbjDhJINmdGxidnnhZoltcXS7IHHzd4F6NCCLQ{WwQVI1Njh5NEmg{txO MoPlV2FPT0WU
NCI-H1963 MUnHdo94fGhiaX7obYJqfGmxbjDhd5NigQ>? Ml74TY5pcWKrdHnvckBw\iCqdX3hckBPS0lvSEG5OlMh[2WubDDndo94fGhiaX6gZUBk\WyuII\pZYJqdGm2eTDhd5NigSxiSVO1NF0yNjJ5OEO5JO69VQ>? NUXVUFl2W0GQR1XS
NCI-H2081 M{XtWmdzd3e2aDDpcohq[mm2aX;uJIF{e2G7 NFHvO5ZKdmirYnn0bY9vKG:oIHj1cYFvKE6FST3INlA5OSClZXzsJIdzd3e2aDDpckBiKGOnbHygeoli[mmuaYT5JIF{e2G7LDDJR|UxRTN2Lk[wOFQh|ryP MljuV2FPT0WU
NCI-H209 NInINItIem:5dHigbY5pcWKrdHnvckBie3OjeR?= MVfJcohq[mm2aX;uJI9nKGi3bXHuJG5EUS2KMkC5JINmdGxiZ4Lve5RpKGmwIHGgZ4VtdCC4aXHibYxqfHliYYPzZZktKEmFNUC9NlIvPjJ5MjFOwG0> NF7ZSnFUSU6JRWK=
NCI-H2107 M{jhbWdzd3e2aDDpcohq[mm2aX;uJIF{e2G7 MXzJcohq[mm2aX;uJI9nKGi3bXHuJG5EUS2KMkGwO{Bk\WyuIHfyc5d1cCCrbjDhJINmdGxidnnhZoltcXS7IHHzd4F6NCCLQ{WwQVI2NjZ3NkGg{txO MX3TRW5ITVJ?
NCI-H2126 NGTa[JpIem:5dHigbY5pcWKrdHnvckBie3OjeR?= MWLJcohq[mm2aX;uJI9nKGi3bXHuJG5EUS2KMkGyOkBk\WyuIHfyc5d1cCCrbjDhJINmdGxidnnhZoltcXS7IHHzd4F6NCCLQ{WwQVYvPTB2Mk[g{txO MVjTRW5ITVJ?
NCI-H2171 MWXHdo94fGhiaX7obYJqfGmxbjDhd5NigQ>? NVjhdJdLUW6qaXLpeIlwdiCxZjDoeY1idiCQQ1mtTFIyPzFiY3XscEBoem:5dHigbY4h[SClZXzsJJZq[WKrbHn0fUBie3OjeTygTWM2OD1yLkm1PVM4KM7:TR?= M2nMXXNCVkeHUh?=
NCI-H2227 MVnHdo94fGhiaX7obYJqfGmxbjDhd5NigQ>? MofFTY5pcWKrdHnvckBw\iCqdX3hckBPS0lvSEKyNlch[2WubDDndo94fGhiaX6gZUBk\WyuII\pZYJqdGm2eTDhd5NigSxiSVO1NF04Njh6NkG2JO69VQ>? NIDkfmlUSU6JRWK=
NCI-H524 NIjHNJpIem:5dHigbY5pcWKrdHnvckBie3OjeR?= NVvERog2UW6qaXLpeIlwdiCxZjDoeY1idiCQQ1mtTFUzPCClZXzsJIdzd3e2aDDpckBiKGOnbHygeoli[mmuaYT5JIF{e2G7LDDJR|UxRTJ{Lki3OlMh|ryP NIjKOI5USU6JRWK=
NCI-H526 NIS3T4lIem:5dHigbY5pcWKrdHnvckBie3OjeR?= NYTLVoFMUW6qaXLpeIlwdiCxZjDoeY1idiCQQ1mtTFUzPiClZXzsJIdzd3e2aDDpckBiKGOnbHygeoli[mmuaYT5JIF{e2G7LDDJR|UxRTF6LkW0N|Eh|ryP Mk\CV2FPT0WU
NCI-H720 M1P6[2dzd3e2aDDpcohq[mm2aX;uJIF{e2G7 NH[zPJlKdmirYnn0bY9vKG:oIHj1cYFvKE6FST3IO|IxKGOnbHyg[5Jwf3SqIHnuJIEh[2WubDD2bYFjcWyrdImgZZN{[XluIFnDOVA:Oi52NUG2NUDPxE1? NYLmVGN1W0GQR1XS
NMC-G1 MWDHdo94fGhiaX7obYJqfGmxbjDhd5NigQ>? NVT6d21{UW6qaXLpeIlwdiCxZjDoeY1idiCQTVOtS|Eh[2WubDDndo94fGhiaX6gZUBk\WyuII\pZYJqdGm2eTDhd5NigSxiSVO1NF0yPS5yNUe4JO69VQ>? MWXTRW5ITVJ?
NOS-1 cell NXPBNWhYT3Kxd4ToJIlvcGmkaYTpc44h[XO|YYm= NFzp[VFKdmirYnn0bY9vKG:oIHj1cYFvKE6RUz2xJINmdGxiZ4Lve5RpKGmwIHGgZ4VtdCC4aXHibYxqfHliYYPzZZktKEmFNUC9OU45OjJ7NDFOwG0> MlGzV2FPT0WU
OCI-AML2 cell MoOzS5Jwf3SqIHnubIljcXSrb36gZZN{[Xl? NVfXSY0yUW6qaXLpeIlwdiCxZjDoeY1idiCRQ1mtRW1NOiClZXzsJIdzd3e2aDDpckBiKGOnbHygeoli[mmuaYT5JIF{e2G7LDDJR|UxRTFyLkm0PVYh|ryP M13VeHNCVkeHUh?=
OCUB-M cell MXLHdo94fGhiaX7obYJqfGmxbjDhd5NigQ>? M2jUfWlvcGmkaYTpc44hd2ZiaIXtZY4hV0OXQj3NJINmdGxiZ4Lve5RpKGmwIHGgZ4VtdCC4aXHibYxqfHliYYPzZZktKEmFNUC9NVcvOjBzIN88US=> MXzTRW5ITVJ?
ONS-76 cell MniwS5Jwf3SqIHnubIljcXSrb36gZZN{[Xl? M{C5S2lvcGmkaYTpc44hd2ZiaIXtZY4hV06VLUe2JINmdGxiZ4Lve5RpKGmwIHGgZ4VtdCC4aXHibYxqfHliYYPzZZktKEmFNUC9NVMvQTF7MTFOwG0> NVK4NXFvW0GQR1XS
OS-RC-2 cell MorOS5Jwf3SqIHnubIljcXSrb36gZZN{[Xl? MmLkTY5pcWKrdHnvckBw\iCqdX3hckBQWy2UQz2yJINmdGxiZ4Lve5RpKGmwIHGgZ4VtdCC4aXHibYxqfHliYYPzZZktKEmFNUC9OFYvOTl3IN88US=> MVzTRW5ITVJ?
OVCAR-4 cell NE\WdXhIem:5dHigbY5pcWKrdHnvckBie3OjeR?= NEjGNnpKdmirYnn0bY9vKG:oIHj1cYFvKE:YQ1HSMVQh[2WubDDndo94fGhiaX6gZUBk\WyuII\pZYJqdGm2eTDhd5NigSxiSVO1NF05NjdzOEC4JO69VQ>? NF\URZZUSU6JRWK=
P30-OHK cell MkHTS5Jwf3SqIHnubIljcXSrb36gZZN{[Xl? NUDOXotCUW6qaXLpeIlwdiCxZjDoeY1idiCSM{CtU2hMKGOnbHyg[5Jwf3SqIHnuJIEh[2WubDD2bYFjcWyrdImgZZN{[XluIFnDOVA:Py54Mki3O{DPxE1? MmLyV2FPT0WU
P30-OHK cell MUjHdo94fGhiaX7obYJqfGmxbjDhd5NigQ>? M3HCVGlvcGmkaYTpc44hd2ZiaIXtZY4hWEZvM{iyJINmdGxiZ4Lve5RpKGmwIHGgZ4VtdCC4aXHibYxqfHliYYPzZZktKEmFNUC9O{4xPDl3NDFOwG0> MoTnV2FPT0WU
PSN1 cell M1[2VWdzd3e2aDDpcohq[mm2aX;uJIF{e2G7 MWfJcohq[mm2aX;uJI9nKGi3bXHuJHBUVjFiY3XscEBoem:5dHigbY4h[SClZXzsJJZq[WKrbHn0fUBie3OjeTygTWM2OD14LkKyNVI3KM7:TR?= MYDTRW5ITVJ?
QIMR-WIL cell NH[4bnRIem:5dHigbY5pcWKrdHnvckBie3OjeR?= NV3ndYRxUW6qaXLpeIlwdiCxZjDoeY1idiCTSV3SMXdKVCClZXzsJIdzd3e2aDDpckBiKGOnbHygeoli[mmuaYT5JIF{e2G7LDDJR|UxRTBwNEmwNFQh|ryP Mkj2V2FPT0WU
RCC10RGB cell NH7TRpBIem:5dHigbY5pcWKrdHnvckBie3OjeR?= MUXJcohq[mm2aX;uJI9nKGi3bXHuJHJESzFyUlfCJINmdGxiZ4Lve5RpKGmwIHGgZ4VtdCC4aXHibYxqfHliYYPzZZktKEmFNUC9NVgvQTB|NjFOwG0> M1LKTnNCVkeHUh?=
RKO cell NWjBNpdRT3Kxd4ToJIlvcGmkaYTpc44h[XO|YYm= MmXWTY5pcWKrdHnvckBw\iCqdX3hckBTU09iY3XscEBoem:5dHigbY4h[SClZXzsJJZq[WKrbHn0fUBie3OjeTygTWM2OD1zMD61OlYzKM7:TR?= MlHTV2FPT0WU
RL95-2 cell Mn76S5Jwf3SqIHnubIljcXSrb36gZZN{[Xl? NFPUbW1KdmirYnn0bY9vKG:oIHj1cYFvKFKOOUWtNkBk\WyuIHfyc5d1cCCrbjDhJINmdGxidnnhZoltcXS7IHHzd4F6NCCLQ{WwQVExNjZ5IN88US=> M2\wW3NCVkeHUh?=
RPMI-6666 cell MkfIS5Jwf3SqIHnubIljcXSrb36gZZN{[Xl? MWLJcohq[mm2aX;uJI9nKGi3bXHuJHJRVUlvNk[2OkBk\WyuIHfyc5d1cCCrbjDhJINmdGxidnnhZoltcXS7IHHzd4F6NCCLQ{WwQVE5NjV{M{[g{txO NWHVPWl3W0GQR1XS
RPMI-8402 cell NUS2PWR5T3Kxd4ToJIlvcGmkaYTpc44h[XO|YYm= NFTtUmVKdmirYnn0bY9vKG:oIHj1cYFvKFKSTVmtPFQxOiClZXzsJIdzd3e2aDDpckBiKGOnbHygeoli[mmuaYT5JIF{e2G7LDDJR|UxRTRwNUi1OkDPxE1? NVHkWFVMW0GQR1XS
RXF393 cell MWrHdo94fGhiaX7obYJqfGmxbjDhd5NigQ>? M{CxWmlvcGmkaYTpc44hd2ZiaIXtZY4hWliIM{mzJINmdGxiZ4Lve5RpKGmwIHGgZ4VtdCC4aXHibYxqfHliYYPzZZktKEmFNUC9NE4{QTNizszN MnnjV2FPT0WU
Ramos-2G6-4C10 cell NV7me2JPT3Kxd4ToJIlvcGmkaYTpc44h[XO|YYm= NFjW[4VKdmirYnn0bY9vKG:oIHj1cYFvKFKjbX;zMVJIPi12Q{GwJINmdGxiZ4Lve5RpKGmwIHGgZ4VtdCC4aXHibYxqfHliYYPzZZktKEmFNUC9NU4{PTdizszN NECyb4hUSU6JRWK=
SCLC-21H cell M1XqVGdzd3e2aDDpcohq[mm2aX;uJIF{e2G7 M2HWfmlvcGmkaYTpc44hd2ZiaIXtZY4hW0OOQz2yNWgh[2WubDDndo94fGhiaX6gZUBk\WyuII\pZYJqdGm2eTDhd5NigSxiSVO1NF04NjZzMUS5JO69VQ>? MmHqV2FPT0WU
SF126 cell M2nZUmdzd3e2aDDpcohq[mm2aX;uJIF{e2G7 Mn\MTY5pcWKrdHnvckBw\iCqdX3hckBUTjF{NjDj[YxtKGe{b4f0bEBqdiCjIHPlcIwhfmmjYnnsbZR6KGG|c3H5MEBKSzVyPUGxMlg{OjIQvF2= M{W1PXNCVkeHUh?=
SF268 cell MnnjS5Jwf3SqIHnubIljcXSrb36gZZN{[Xl? NUnzWHNoUW6qaXLpeIlwdiCxZjDoeY1idiCVRkK2PEBk\WyuIHfyc5d1cCCrbjDhJINmdGxidnnhZoltcXS7IHHzd4F6NCCLQ{WwQVYvOjNzOEOg{txO NVruUIhwW0GQR1XS
SF539 cell M4\BOWdzd3e2aDDpcohq[mm2aX;uJIF{e2G7 M4jJbGlvcGmkaYTpc44hd2ZiaIXtZY4hW0Z3M{mgZ4VtdCCpcn;3eIghcW5iYTDj[YxtKH[rYXLpcIl1gSCjc4PhfUwhUUN3ME2xMlI5PjZzIN88US=> M4jROnNCVkeHUh?=
SH-4 cell NULtfnJ6T3Kxd4ToJIlvcGmkaYTpc44h[XO|YYm= NGTNSGhKdmirYnn0bY9vKG:oIHj1cYFvKFOKLUSgZ4VtdCCpcn;3eIghcW5iYTDj[YxtKH[rYXLpcIl1gSCjc4PhfUwhUUN3ME21Mlc2PTB6IN88US=> MX7TRW5ITVJ?
SIG-M5 cell MkfnS5Jwf3SqIHnubIljcXSrb36gZZN{[Xl? MoT0TY5pcWKrdHnvckBw\iCqdX3hckBUUUdvTUWgZ4VtdCCpcn;3eIghcW5iYTDj[YxtKH[rYXLpcIl1gSCjc4PhfUwhUUN3ME2xNU44OjV7IN88US=> NFHGSVdUSU6JRWK=
SJSA-1 cell MU\Hdo94fGhiaX7obYJqfGmxbjDhd5NigQ>? NX\uZ5k5UW6qaXLpeIlwdiCxZjDoeY1idiCVSmPBMVEh[2WubDDndo94fGhiaX6gZUBk\WyuII\pZYJqdGm2eTDhd5NigSxiSVO1NF0yNjB2NUK2JO69VQ>? MX;TRW5ITVJ?
SK-LMS-1 cell Mmr4S5Jwf3SqIHnubIljcXSrb36gZZN{[Xl? M2naWGlvcGmkaYTpc44hd2ZiaIXtZY4hW0tvTF3TMVEh[2WubDDndo94fGhiaX6gZUBk\WyuII\pZYJqdGm2eTDhd5NigSxiSVO1NF0{Oi53OU[1JO69VQ>? MmjxV2FPT0WU
SK-MM-2 cell MoPPS5Jwf3SqIHnubIljcXSrb36gZZN{[Xl? NWHwUVNCUW6qaXLpeIlwdiCxZjDoeY1idiCVSz3NUU0zKGOnbHyg[5Jwf3SqIHnuJIEh[2WubDD2bYFjcWyrdImgZZN{[XluIFnDOVA:PDJwM{SwOUDPxE1? NUPFOHZQW0GQR1XS
SK-N-DZ cell NV\rb|dMT3Kxd4ToJIlvcGmkaYTpc44h[XO|YYm= MVzJcohq[mm2aX;uJI9nKGi3bXHuJHNMNU5vRGqgZ4VtdCCpcn;3eIghcW5iYTDj[YxtKH[rYXLpcIl1gSCjc4PhfUwhUUN3ME25MlQ5OzF2IN88US=> NV;vbo05W0GQR1XS
SK-NEP-1 cell NFK4VoVIem:5dHigbY5pcWKrdHnvckBie3OjeR?= NEDsbmZKdmirYnn0bY9vKG:oIHj1cYFvKFONLV7FVE0yKGOnbHyg[5Jwf3SqIHnuJIEh[2WubDD2bYFjcWyrdImgZZN{[XluIFnDOVA:OTdwNUS1OkDPxE1? MmT0V2FPT0WU
SK-PN-DW cell NXm1NZVMT3Kxd4ToJIlvcGmkaYTpc44h[XO|YYm= MnXWTY5pcWKrdHnvckBw\iCqdX3hckBUUy2STj3EW{Bk\WyuIHfyc5d1cCCrbjDhJINmdGxidnnhZoltcXS7IHHzd4F6NCCLQ{WwQVI1Njl5M{[g{txO NVTuS|J1W0GQR1XS
SNB75 cell M3f6[Wdzd3e2aDDpcohq[mm2aX;uJIF{e2G7 MkPSTY5pcWKrdHnvckBw\iCqdX3hckBUVkJ5NTDj[YxtKGe{b4f0bEBqdiCjIHPlcIwhfmmjYnnsbZR6KGG|c3H5MEBKSzVyPUiuNFc4OzdizszN MojMV2FPT0WU
SR cell NWC3THl4T3Kxd4ToJIlvcGmkaYTpc44h[XO|YYm= MYXJcohq[mm2aX;uJI9nKGi3bXHuJHNTKGOnbHyg[5Jwf3SqIHnuJIEh[2WubDD2bYFjcWyrdImgZZN{[XluIFnDOVA:OC5yMECxN|ch|ryP NVnLUVJNW0GQR1XS
SU-DHL-1 cell NXK1SIo6T3Kxd4ToJIlvcGmkaYTpc44h[XO|YYm= MmXVTY5pcWKrdHnvckBw\iCqdX3hckBUXS2GSFytNUBk\WyuIHfyc5d1cCCrbjDhJINmdGxidnnhZoltcXS7IHHzd4F6NCCLQ{WwQVEzNjd|M{[g{txO MVzTRW5ITVJ?
SW684 cell MnfOS5Jwf3SqIHnubIljcXSrb36gZZN{[Xl? MYLJcohq[mm2aX;uJI9nKGi3bXHuJHNYPjh2IHPlcIwh\3Kxd4ToJIlvKGFiY3XscEB3cWGkaXzpeJkh[XO|YYmsJGlEPTB;M{muNFEyKM7:TR?= NHrD[WxUSU6JRWK=
SW872 cell M2TQPGdzd3e2aDDpcohq[mm2aX;uJIF{e2G7 M{HaNWlvcGmkaYTpc44hd2ZiaIXtZY4hW1d6N{KgZ4VtdCCpcn;3eIghcW5iYTDj[YxtKH[rYXLpcIl1gSCjc4PhfUwhUUN3ME2wMlg5PjV4IN88US=> M4jVWXNCVkeHUh?=
SW962 cell NHL0XWxIem:5dHigbY5pcWKrdHnvckBie3OjeR?= NUDPS3BWUW6qaXLpeIlwdiCxZjDoeY1idiCVV{m2NkBk\WyuIHfyc5d1cCCrbjDhJINmdGxidnnhZoltcXS7IHHzd4F6NCCLQ{WwQVEzNjd3MkGg{txO MUXTRW5ITVJ?
697 cell NETKVmhIem:5dHigbY5pcWKrdHnvckBie3OjeR?= NU\tdItSUW6qaXLpeIlwdiCxZjDoeY1idiB4OUegZ4VtdCCpcn;3eIghcW5iYTDj[YxtKH[rYXLpcIl1gSCjc4PhfUwhUUN3ME2wMlI6QTFizszN NXj2O4ZtW0GQR1XS
8-MG-BA cell MnzXS5Jwf3SqIHnubIljcXSrb36gZZN{[Xl? M2XsUmlvcGmkaYTpc44hd2ZiaIXtZY4hQC2PRz3CRUBk\WyuIHfyc5d1cCCrbjDhJINmdGxidnnhZoltcXS7IHHzd4F6NCCLQ{WwQVI{NjB5OUOg{txO MoXNV2FPT0WU
A101D cell MVvHdo94fGhiaX7obYJqfGmxbjDhd5NigQ>? NIPyU4JKdmirYnn0bY9vKG:oIHj1cYFvKEFzMEHEJINmdGxiZ4Lve5RpKGmwIHGgZ4VtdCC4aXHibYxqfHliYYPzZZktKEmFNUC9NU45PzB|NDFOwG0> MYLTRW5ITVJ?
ACN cell MXPHdo94fGhiaX7obYJqfGmxbjDhd5NigQ>? M17PNmlvcGmkaYTpc44hd2ZiaIXtZY4hSUOQIHPlcIwh\3Kxd4ToJIlvKGFiY3XscEB3cWGkaXzpeJkh[XO|YYmsJGlEPTB;MkGuOFM5PyEQvF2= M1LzZXNCVkeHUh?=
AM-38 cell NUDOUnZsT3Kxd4ToJIlvcGmkaYTpc44h[XO|YYm= NFOwVoxKdmirYnn0bY9vKG:oIHj1cYFvKEGPLUO4JINmdGxiZ4Lve5RpKGmwIHGgZ4VtdCC4aXHibYxqfHliYYPzZZktKEmFNUC9O{4zPjN{NzFOwG0> M3zZWXNCVkeHUh?=
ATN-1 cell MX\Hdo94fGhiaX7obYJqfGmxbjDhd5NigQ>? NF7ocGNKdmirYnn0bY9vKG:oIHj1cYFvKEGWTj2xJINmdGxiZ4Lve5RpKGmwIHGgZ4VtdCC4aXHibYxqfHliYYPzZZktKEmFNUC9NlQvPzV3NTFOwG0> M1PlbXNCVkeHUh?=
BB30-HNC cell MX\Hdo94fGhiaX7obYJqfGmxbjDhd5NigQ>? MmThTY5pcWKrdHnvckBw\iCqdX3hckBDSjNyLVjOR{Bk\WyuIHfyc5d1cCCrbjDhJINmdGxidnnhZoltcXS7IHHzd4F6NCCLQ{WwQVIzNjJ3M{Kg{txO MkHIV2FPT0WU
BB49-HNC cell NVP5cpVGT3Kxd4ToJIlvcGmkaYTpc44h[XO|YYm= NGLEOnpKdmirYnn0bY9vKG:oIHj1cYFvKEKENEmtTG5EKGOnbHyg[5Jwf3SqIHnuJIEh[2WubDD2bYFjcWyrdImgZZN{[XluIFnDOVA:OC5yMEe4PUDPxE1? NUfDd4dqW0GQR1XS
human BC-1 cell M{XKR2dzd3e2aDDpcohq[mm2aX;uJIF{e2G7 Mn7ETY5pcWKrdHnvckBw\iCqdX3hckBDSy1zIHPlcIwh\3Kxd4ToJIlvKGFiY3XscEB3cWGkaXzpeJkh[XO|YYmsJGlEPTB;Mz65O|ExPyEQvF2= M37YZnNCVkeHUh?=
BE-13 cell NUnJV4J3T3Kxd4ToJIlvcGmkaYTpc44h[XO|YYm= MYjJcohq[mm2aX;uJI9nKGi3bXHuJGJGNTF|IHPlcIwh\3Kxd4ToJIlvKGFiY3XscEB3cWGkaXzpeJkh[XO|YYmsJGlEPTB;MD6xOFA5Oc7:TR?= M2rQTnNCVkeHUh?=
BL-70 cell NEj4cplIem:5dHigbY5pcWKrdHnvckBie3OjeR?= NXPhTVIxUW6qaXLpeIlwdiCxZjDoeY1idiCETD23NEBk\WyuIHfyc5d1cCCrbjDhJINmdGxidnnhZoltcXS7IHHzd4F6NCCLQ{WwQVMvPDB5MEOg{txO NUT4XGo{W0GQR1XS
BV-173 cell NVLscmZNT3Kxd4ToJIlvcGmkaYTpc44h[XO|YYm= NIrSNm1KdmirYnn0bY9vKG:oIHj1cYFvKEKYLUG3N{Bk\WyuIHfyc5d1cCCrbjDhJINmdGxidnnhZoltcXS7IHHzd4F6NCCLQ{WwQVE5Njh6NUmg{txO Ml\aV2FPT0WU
Becker cell MknZS5Jwf3SqIHnubIljcXSrb36gZZN{[Xl? NIr6eVRKdmirYnn0bY9vKG:oIHj1cYFvKEKnY3vldkBk\WyuIHfyc5d1cCCrbjDhJINmdGxidnnhZoltcXS7IHHzd4F6NCCLQ{WwQVE{Njl3NEWg{txO NGD4Rm1USU6JRWK=
CAL-148 cell MUHHdo94fGhiaX7obYJqfGmxbjDhd5NigQ>? M2fjNGlvcGmkaYTpc44hd2ZiaIXtZY4hS0GOLUG0PEBk\WyuIHfyc5d1cCCrbjDhJINmdGxidnnhZoltcXS7IHHzd4F6NCCLQ{WwQVM2NjZ3NUeg{txO MUTTRW5ITVJ?
TE-10 cell MWfHdo94fGhiaX7obYJqfGmxbjDhd5NigQ>? M1PJfWlvcGmkaYTpc44hd2ZiaIXtZY4hXEVvMUCgZ4VtdCCpcn;3eIghcW5iYTDj[YxtKH[rYXLpcIl1gSCjc4PhfUwhUUN3ME2yNk45PDJ|IN88US=> NGfUdXRUSU6JRWK=
TE-12 cell NWP1cWRVT3Kxd4ToJIlvcGmkaYTpc44h[XO|YYm= MXvJcohq[mm2aX;uJI9nKGi3bXHuJHRGNTF{IHPlcIwh\3Kxd4ToJIlvKGFiY3XscEB3cWGkaXzpeJkh[XO|YYmsJGlEPTB;M{KuOFEyPCEQvF2= MXLTRW5ITVJ?
TE-8 cell MXHHdo94fGhiaX7obYJqfGmxbjDhd5NigQ>? NV:2S2RUUW6qaXLpeIlwdiCxZjDoeY1idiCWRT24JINmdGxiZ4Lve5RpKGmwIHGgZ4VtdCC4aXHibYxqfHliYYPzZZktKEmFNUC9NVEvPjB6OTFOwG0> MmTmV2FPT0WU
TE-9 cell NFjwXZFIem:5dHigbY5pcWKrdHnvckBie3OjeR?= NEDqN|NKdmirYnn0bY9vKG:oIHj1cYFvKFSHLUmgZ4VtdCCpcn;3eIghcW5iYTDj[YxtKH[rYXLpcIl1gSCjc4PhfUwhUUN3ME2zOk43OzhzIN88US=> MVrTRW5ITVJ?
TGW cell NV7WW4tFT3Kxd4ToJIlvcGmkaYTpc44h[XO|YYm= NITKOnlKdmirYnn0bY9vKG:oIHj1cYFvKFSJVzDj[YxtKGe{b4f0bEBqdiCjIHPlcIwhfmmjYnnsbZR6KGG|c3H5MEBKSzVyPUKzMlM2PzdizszN NWLtOnRGW0GQR1XS
UACC-257 cell M33qWGdzd3e2aDDpcohq[mm2aX;uJIF{e2G7 MYPJcohq[mm2aX;uJI9nKGi3bXHuJHVCS0NvMkW3JINmdGxiZ4Lve5RpKGmwIHGgZ4VtdCC4aXHibYxqfHliYYPzZZktKEmFNUC9PE44ODZ{NTFOwG0> Ml;2V2FPT0WU
WSU-NHL cell MV\Hdo94fGhiaX7obYJqfGmxbjDhd5NigQ>? M1LrTmlvcGmkaYTpc44hd2ZiaIXtZY4hX1OXLV7IUEBk\WyuIHfyc5d1cCCrbjDhJINmdGxidnnhZoltcXS7IHHzd4F6NCCLQ{WwQVI4NjF7MEeg{txO MoLiV2FPT0WU
no-10 cell Mo\BS5Jwf3SqIHnubIljcXSrb36gZZN{[Xl? MVPJcohq[mm2aX;uJI9nKGi3bXHuJI5wNTFyIHPlcIwh\3Kxd4ToJIlvKGFiY3XscEB3cWGkaXzpeJkh[XO|YYmsJGlEPTB;MD62Olg1PiEQvF2= NGXTPIFUSU6JRWK=
no-11 cell M{W3eGdzd3e2aDDpcohq[mm2aX;uJIF{e2G7 NV3xdnh6UW6qaXLpeIlwdiCxZjDoeY1idiCwbz2xNUBk\WyuIHfyc5d1cCCrbjDhJINmdGxidnnhZoltcXS7IHHzd4F6NCCLQ{WwQVQ4NjB{NkOg{txO MXXTRW5ITVJ?
CAS-1 cell M3\0Tmdzd3e2aDDpcohq[mm2aX;uJIF{e2G7 MUPJcohq[mm2aX;uJI9nKGi3bXHuJGNCWy1zIHPlcIwh\3Kxd4ToJIlvKGFiY3XscEB3cWGkaXzpeJkh[XO|YYmsJGlEPTB;MD64OFch|ryP NVPOOnF2W0GQR1XS
CCRF-CEM cell MYTHdo94fGhiaX7obYJqfGmxbjDhd5NigQ>? NF;EOpZKdmirYnn0bY9vKG:oIHj1cYFvKEOFUl[tR2VOKGOnbHyg[5Jwf3SqIHnuJIEh[2WubDD2bYFjcWyrdImgZZN{[XluIFnDOVA:QC54NUO5NkDPxE1? NGrWfpdUSU6JRWK=
CMK cell NUTCXZZyT3Kxd4ToJIlvcGmkaYTpc44h[XO|YYm= MV;Jcohq[mm2aX;uJI9nKGi3bXHuJGNOUyClZXzsJIdzd3e2aDDpckBiKGOnbHygeoli[mmuaYT5JIF{e2G7LDDJR|UxRTFwMEGzNlMh|ryP MkXTV2FPT0WU
COLO-829 cell NHrYVYZIem:5dHigbY5pcWKrdHnvckBie3OjeR?= MWrJcohq[mm2aX;uJI9nKGi3bXHuJGNQVE9vOEK5JINmdGxiZ4Lve5RpKGmwIHGgZ4VtdCC4aXHibYxqfHliYYPzZZktKEmFNUC9N{4zPDJ{NjFOwG0> MVnTRW5ITVJ?
COR-L279 cell MWfHdo94fGhiaX7obYJqfGmxbjDhd5NigQ>? NGfEcWRKdmirYnn0bY9vKG:oIHj1cYFvKEORUj3MNlc6KGOnbHyg[5Jwf3SqIHnuJIEh[2WubDD2bYFjcWyrdImgZZN{[XluIFnDOVA:Oi5yN{O4JO69VQ>? MnT4V2FPT0WU
CP66-MEL cell M4e4TWdzd3e2aDDpcohq[mm2aX;uJIF{e2G7 NInSUG9KdmirYnn0bY9vKG:oIHj1cYFvKEOSNk[tUWVNKGOnbHyg[5Jwf3SqIHnuJIEh[2WubDD2bYFjcWyrdImgZZN{[XluIFnDOVA:OzZwNUS5O{DPxE1? MWfTRW5ITVJ?
CRO-AP2 cell MXPHdo94fGhiaX7obYJqfGmxbjDhd5NigQ>? NXHrS2J7UW6qaXLpeIlwdiCxZjDoeY1idiCFUl:tRXAzKGOnbHyg[5Jwf3SqIHnuJIEh[2WubDD2bYFjcWyrdImgZZN{[XluIFnDOVA:Oi5|NkC4PEDPxE1? NWCxe2hDW0GQR1XS
CTV-1 cell M3PXbmdzd3e2aDDpcohq[mm2aX;uJIF{e2G7 MUXJcohq[mm2aX;uJI9nKGi3bXHuJGNVXi1zIHPlcIwh\3Kxd4ToJIlvKGFiY3XscEB3cWGkaXzpeJkh[XO|YYmsJGlEPTB;MkOuPVE1PSEQvF2= NI[4WJNUSU6JRWK=
Calu-6 cell MYHHdo94fGhiaX7obYJqfGmxbjDhd5NigQ>? MX;Jcohq[mm2aX;uJI9nKGi3bXHuJGNidHVvNjDj[YxtKGe{b4f0bEBqdiCjIHPlcIwhfmmjYnnsbZR6KGG|c3H5MEBKSzVyPUS3MlU5PiEQvF2= MlnSV2FPT0WU
D-247MG cell MVvHdo94fGhiaX7obYJqfGmxbjDhd5NigQ>? MmS4TY5pcWKrdHnvckBw\iCqdX3hckBFNTJ2N13HJINmdGxiZ4Lve5RpKGmwIHGgZ4VtdCC4aXHibYxqfHliYYPzZZktKEmFNUC9NE43OjhzNDFOwG0> NX74OI4xW0GQR1XS
D-263MG cell NEjvSZJIem:5dHigbY5pcWKrdHnvckBie3OjeR?= NILyUoJKdmirYnn0bY9vKG:oIHj1cYFvKERvMk[zUWch[2WubDDndo94fGhiaX6gZUBk\WyuII\pZYJqdGm2eTDhd5NigSxiSVO1NF0xNjB6NUC5JO69VQ>? NHy3R25USU6JRWK=
D-336MG cell MYTHdo94fGhiaX7obYJqfGmxbjDhd5NigQ>? NUnj[mhUUW6qaXLpeIlwdiCxZjDoeY1idiCGLUOzOm1IKGOnbHyg[5Jwf3SqIHnuJIEh[2WubDD2bYFjcWyrdImgZZN{[XluIFnDOVA:OC54Mki1OEDPxE1? MYXTRW5ITVJ?
D-392MG cell NX3lU5R3T3Kxd4ToJIlvcGmkaYTpc44h[XO|YYm= NWS5[nB[UW6qaXLpeIlwdiCxZjDoeY1idiCGLUO5Nm1IKGOnbHyg[5Jwf3SqIHnuJIEh[2WubDD2bYFjcWyrdImgZZN{[XluIFnDOVA:OS52M{CzPUDPxE1? NX3v[GZNW0GQR1XS
D-502MG cell NUTJVoJ[T3Kxd4ToJIlvcGmkaYTpc44h[XO|YYm= NXnCbIplUW6qaXLpeIlwdiCxZjDoeY1idiCGLUWwNm1IKGOnbHyg[5Jwf3SqIHnuJIEh[2WubDD2bYFjcWyrdImgZZN{[XluIFnDOVA:QC53M{S5NkDPxE1? NFT6ZZNUSU6JRWK=
D-542MG cell MleyS5Jwf3SqIHnubIljcXSrb36gZZN{[Xl? MVPJcohq[mm2aX;uJI9nKGi3bXHuJGQuPTR{TVegZ4VtdCCpcn;3eIghcW5iYTDj[YxtKH[rYXLpcIl1gSCjc4PhfUwhUUN3ME2xNk4{OTV{IN88US=> MWjTRW5ITVJ?
DB cell M1Llb2dzd3e2aDDpcohq[mm2aX;uJIF{e2G7 MXPJcohq[mm2aX;uJI9nKGi3bXHuJGRDKGOnbHyg[5Jwf3SqIHnuJIEh[2WubDD2bYFjcWyrdImgZZN{[XluIFnDOVA:PDdwMUSxO{DPxE1? MX3TRW5ITVJ?
DEL cell M1zsNmdzd3e2aDDpcohq[mm2aX;uJIF{e2G7 Mn\pTY5pcWKrdHnvckBw\iCqdX3hckBFTUxiY3XscEBoem:5dHigbY4h[SClZXzsJJZq[WKrbHn0fUBie3OjeTygTWM2OD15LkCxPFk5KM7:TR?= M2f3NXNCVkeHUh?=
DMS-114 cell NFj2Wo1Iem:5dHigbY5pcWKrdHnvckBie3OjeR?= MYLJcohq[mm2aX;uJI9nKGi3bXHuJGROWy1zMUSgZ4VtdCCpcn;3eIghcW5iYTDj[YxtKH[rYXLpcIl1gSCjc4PhfUwhUUN3ME20PU45PDZ6IN88US=> NFjSUG1USU6JRWK=
DMS-153 cell NFnIPIdIem:5dHigbY5pcWKrdHnvckBie3OjeR?= MY\Jcohq[mm2aX;uJI9nKGi3bXHuJGROWy1zNUOgZ4VtdCCpcn;3eIghcW5iYTDj[YxtKH[rYXLpcIl1gSCjc4PhfUwhUUN3ME20Nk46QTJ|IN88US=> NW\vUIpSW0GQR1XS
DOHH-2 cell M3XuRWdzd3e2aDDpcohq[mm2aX;uJIF{e2G7 MmnWTY5pcWKrdHnvckBw\iCqdX3hckBFV0iKLUKgZ4VtdCCpcn;3eIghcW5iYTDj[YxtKH[rYXLpcIl1gSCjc4PhfUwhUUN3ME20MlIzPzZ2IN88US=> MVHTRW5ITVJ?
DSH1 cell Mlj3S5Jwf3SqIHnubIljcXSrb36gZZN{[Xl? M1X0[2lvcGmkaYTpc44hd2ZiaIXtZY4hTFOKMTDj[YxtKGe{b4f0bEBqdiCjIHPlcIwhfmmjYnnsbZR6KGG|c3H5MEBKSzVyPUiuOFM3OjNizszN Ml32V2FPT0WU
Daudi cell NHTVO3JIem:5dHigbY5pcWKrdHnvckBie3OjeR?= NHTXbopKdmirYnn0bY9vKG:oIHj1cYFvKESjdXTpJINmdGxiZ4Lve5RpKGmwIHGgZ4VtdCC4aXHibYxqfHliYYPzZZktKEmFNUC9Nk4xQThyMjFOwG0> M{L4fHNCVkeHUh?=
EC-GI-10 cell MkfUS5Jwf3SqIHnubIljcXSrb36gZZN{[Xl? NHW1UpBKdmirYnn0bY9vKG:oIHj1cYFvKEWFLVfJMVExKGOnbHyg[5Jwf3SqIHnuJIEh[2WubDD2bYFjcWyrdImgZZN{[XluIFnDOVA:PDRwMkW4PUDPxE1? NV\5cGE6W0GQR1XS
ECC4 cell MV\Hdo94fGhiaX7obYJqfGmxbjDhd5NigQ>? M1G1dmlvcGmkaYTpc44hd2ZiaIXtZY4hTUOFNDDj[YxtKGe{b4f0bEBqdiCjIHPlcIwhfmmjYnnsbZR6KGG|c3H5MEBKSzVyPUOyMlE5QTZizszN MlnOV2FPT0WU
EM-2 cell NYTVXJhUT3Kxd4ToJIlvcGmkaYTpc44h[XO|YYm= NHLSOoJKdmirYnn0bY9vKG:oIHj1cYFvKEWPLUKgZ4VtdCCpcn;3eIghcW5iYTDj[YxtKH[rYXLpcIl1gSCjc4PhfUwhUUN3ME2yMlQ2PTl2IN88US=> NXrCfHFJW0GQR1XS
ES1 cell NXv0c5NWT3Kxd4ToJIlvcGmkaYTpc44h[XO|YYm= M32xbGlvcGmkaYTpc44hd2ZiaIXtZY4hTVNzIHPlcIwh\3Kxd4ToJIlvKGFiY3XscEB3cWGkaXzpeJkh[XO|YYmsJGlEPTB;NT61OFA5PyEQvF2= NVHObZEzW0GQR1XS
ES3 cell Mle1S5Jwf3SqIHnubIljcXSrb36gZZN{[Xl? Mo\PTY5pcWKrdHnvckBw\iCqdX3hckBGWzNiY3XscEBoem:5dHigbY4h[SClZXzsJJZq[WKrbHn0fUBie3OjeTygTWM2OD12Mj60O|I6KM7:TR?= M{G2[3NCVkeHUh?=
ES4 cell MnnUS5Jwf3SqIHnubIljcXSrb36gZZN{[Xl? MnuwTY5pcWKrdHnvckBw\iCqdX3hckBGWzRiY3XscEBoem:5dHigbY4h[SClZXzsJJZq[WKrbHn0fUBie3OjeTygTWM2OD1|NT6xPVUh|ryP M{PxdXNCVkeHUh?=
ES6 cell MoLmS5Jwf3SqIHnubIljcXSrb36gZZN{[Xl? NHm0OGJKdmirYnn0bY9vKG:oIHj1cYFvKEWVNjDj[YxtKGe{b4f0bEBqdiCjIHPlcIwhfmmjYnnsbZR6KGG|c3H5MEBKSzVyPUCuNlQ4OzNizszN NUKzVWE5W0GQR1XS
ES7 cell NHG4TFRIem:5dHigbY5pcWKrdHnvckBie3OjeR?= MoDJTY5pcWKrdHnvckBw\iCqdX3hckBGWzdiY3XscEBoem:5dHigbY4h[SClZXzsJJZq[WKrbHn0fUBie3OjeTygTWM2OD13LkKzNVI1KM7:TR?= NYfN[4FnW0GQR1XS
ES8 cell NWDmenNUT3Kxd4ToJIlvcGmkaYTpc44h[XO|YYm= MULJcohq[mm2aX;uJI9nKGi3bXHuJGVUQCClZXzsJIdzd3e2aDDpckBiKGOnbHygeoli[mmuaYT5JIF{e2G7LDDJR|UxRTBwOEG5NlQh|ryP NX7VeZlFW0GQR1XS
EW-18 cell M1zD[2dzd3e2aDDpcohq[mm2aX;uJIF{e2G7 NYW0ZVFYUW6qaXLpeIlwdiCxZjDoeY1idiCHVz2xPEBk\WyuIHfyc5d1cCCrbjDhJINmdGxidnnhZoltcXS7IHHzd4F6NCCLQ{WwQVE{NjZ5NUmg{txO MmD0V2FPT0WU
EW-22 cell MmCzS5Jwf3SqIHnubIljcXSrb36gZZN{[Xl? MmPCTY5pcWKrdHnvckBw\iCqdX3hckBGXy1{MjDj[YxtKGe{b4f0bEBqdiCjIHPlcIwhfmmjYnnsbZR6KGG|c3H5MEBKSzVyPUS3Mlc6PDdizszN MXTTRW5ITVJ?
GCIY cell MV3Hdo94fGhiaX7obYJqfGmxbjDhd5NigQ>? M1LZW2lvcGmkaYTpc44hd2ZiaIXtZY4hT0OLWTDj[YxtKGe{b4f0bEBqdiCjIHPlcIwhfmmjYnnsbZR6KGG|c3H5MEBKSzVyPUmuPFA{QDlizszN NVnDZXFIW0GQR1XS
GDM-1 cell NUP1NphGT3Kxd4ToJIlvcGmkaYTpc44h[XO|YYm= M2HWcmlvcGmkaYTpc44hd2ZiaIXtZY4hT0SPLUGgZ4VtdCCpcn;3eIghcW5iYTDj[YxtKH[rYXLpcIl1gSCjc4PhfUwhUUN3ME24MlM6OTl4IN88US=> M4nHNnNCVkeHUh?=
GI-1 cell MYjHdo94fGhiaX7obYJqfGmxbjDhd5NigQ>? MVPJcohq[mm2aX;uJI9nKGi3bXHuJGdKNTFiY3XscEBoem:5dHigbY4h[SClZXzsJJZq[WKrbHn0fUBie3OjeTygTWM2OD1yLkCwOVI{KM7:TR?= M4\0R3NCVkeHUh?=
GI-ME-N cell M2PF[mdzd3e2aDDpcohq[mm2aX;uJIF{e2G7 NXK0fYJbUW6qaXLpeIlwdiCxZjDoeY1idiCJST3NSU1PKGOnbHyg[5Jwf3SqIHnuJIEh[2WubDD2bYFjcWyrdImgZZN{[XluIFnDOVA:OC5yNEm1NUDPxE1? MUXTRW5ITVJ?
GR-ST cell MXXHdo94fGhiaX7obYJqfGmxbjDhd5NigQ>? NX3BeJRuUW6qaXLpeIlwdiCxZjDoeY1idiCJUj3TWEBk\WyuIHfyc5d1cCCrbjDhJINmdGxidnnhZoltcXS7IHHzd4F6NCCLQ{WwQVE{Njd7MEKg{txO M1jQTXNCVkeHUh?=
GT3TKB cell M{\5Xmdzd3e2aDDpcohq[mm2aX;uJIF{e2G7 NITuXW5KdmirYnn0bY9vKG:oIHj1cYFvKEeWM2TLRkBk\WyuIHfyc5d1cCCrbjDhJINmdGxidnnhZoltcXS7IHHzd4F6NCCLQ{WwQVEvPjB|OEmg{txO NXHxcVh4W0GQR1XS
HAL-01 cell NH;ne5dIem:5dHigbY5pcWKrdHnvckBie3OjeR?= M3PXeWlvcGmkaYTpc44hd2ZiaIXtZY4hUEGOLUCxJINmdGxiZ4Lve5RpKGmwIHGgZ4VtdCC4aXHibYxqfHliYYPzZZktKEmFNUC9Ok43QTdzMjFOwG0> M2TM[HNCVkeHUh?=
HCC1599 cell MWnHdo94fGhiaX7obYJqfGmxbjDhd5NigQ>? NWPqSGhqUW6qaXLpeIlwdiCxZjDoeY1idiCKQ1OxOVk6KGOnbHyg[5Jwf3SqIHnuJIEh[2WubDD2bYFjcWyrdImgZZN{[XluIFnDOVA:OzdwNkCxNUDPxE1? Mn:5V2FPT0WU
HCC2218 cell NFO3UHlIem:5dHigbY5pcWKrdHnvckBie3OjeR?= NWDWXYJkUW6qaXLpeIlwdiCxZjDoeY1idiCKQ1OyNlE5KGOnbHyg[5Jwf3SqIHnuJIEh[2WubDD2bYFjcWyrdImgZZN{[XluIFnDOVA:OTNwM{izOEDPxE1? M2jHNHNCVkeHUh?=
HD-MY-Z cell M{LnRmdzd3e2aDDpcohq[mm2aX;uJIF{e2G7 NHmzXFRKdmirYnn0bY9vKG:oIHj1cYFvKEiGLV3ZMXoh[2WubDDndo94fGhiaX6gZUBk\WyuII\pZYJqdGm2eTDhd5NigSxiSVO1NF0zPS5{MUS2JO69VQ>? NIK0WGNUSU6JRWK=
HL-60 cell MlK2S5Jwf3SqIHnubIljcXSrb36gZZN{[Xl? MofiTY5pcWKrdHnvckBw\iCqdX3hckBJVC14MDDj[YxtKGe{b4f0bEBqdiCjIHPlcIwhfmmjYnnsbZR6KGG|c3H5MEBKSzVyPUGyMlIyOTRizszN M4DRPHNCVkeHUh?=
HOP-62 cell M360eWdzd3e2aDDpcohq[mm2aX;uJIF{e2G7 NYmzeoRuUW6qaXLpeIlwdiCxZjDoeY1idiCKT2CtOlIh[2WubDDndo94fGhiaX6gZUBk\WyuII\pZYJqdGm2eTDhd5NigSxiSVO1NF0zOy57NUK3JO69VQ>? M3jXTHNCVkeHUh?=
HT cell M3zIeGdzd3e2aDDpcohq[mm2aX;uJIF{e2G7 MXjJcohq[mm2aX;uJI9nKGi3bXHuJGhVKGOnbHyg[5Jwf3SqIHnuJIEh[2WubDD2bYFjcWyrdImgZZN{[XluIFnDOVA:PC52NEOyNUDPxE1? M1WzVnNCVkeHUh?=
HT-144 cell MUHHdo94fGhiaX7obYJqfGmxbjDhd5NigQ>? M1fHZWlvcGmkaYTpc44hd2ZiaIXtZY4hUFRvMUS0JINmdGxiZ4Lve5RpKGmwIHGgZ4VtdCC4aXHibYxqfHliYYPzZZktKEmFNUC9OE46ODZ6NjFOwG0> NXH2dnp7W0GQR1XS
HUTU-80 cell M2j6Zmdzd3e2aDDpcohq[mm2aX;uJIF{e2G7 NVjzPHNCUW6qaXLpeIlwdiCxZjDoeY1idiCKVWTVMVgxKGOnbHyg[5Jwf3SqIHnuJIEh[2WubDD2bYFjcWyrdImgZZN{[XluIFnDOVA:Oy55OEm4OkDPxE1? NHS2WYlUSU6JRWK=
IST-MEL1 cell NWnmTm9VT3Kxd4ToJIlvcGmkaYTpc44h[XO|YYm= M{P2SmlvcGmkaYTpc44hd2ZiaIXtZY4hUVOWLV3FUFEh[2WubDDndo94fGhiaX6gZUBk\WyuII\pZYJqdGm2eTDhd5NigSxiSVO1NF0{Oi57MEi2JO69VQ>? NFj4cpNUSU6JRWK=
IST-SL1 cell M1PUZmdzd3e2aDDpcohq[mm2aX;uJIF{e2G7 NIrZUFFKdmirYnn0bY9vKG:oIHj1cYFvKEmVVD3TUFEh[2WubDDndo94fGhiaX6gZUBk\WyuII\pZYJqdGm2eTDhd5NigSxiSVO1NF0zNjF5MEe5JO69VQ>? M4mybXNCVkeHUh?=
IST-SL2 cell M1nHVWdzd3e2aDDpcohq[mm2aX;uJIF{e2G7 MX;Jcohq[mm2aX;uJI9nKGi3bXHuJGlUXC2VTEKgZ4VtdCCpcn;3eIghcW5iYTDj[YxtKH[rYXLpcIl1gSCjc4PhfUwhUUN3ME2zMlI3PjB6IN88US=> MXrTRW5ITVJ?
K052 cell NYXCfYtlT3Kxd4ToJIlvcGmkaYTpc44h[XO|YYm= MWXJcohq[mm2aX;uJI9nKGi3bXHuJGsxPTJiY3XscEBoem:5dHigbY4h[SClZXzsJJZq[WKrbHn0fUBie3OjeTygTWM2OD1yLke1N|AyKM7:TR?= NWCwW2xmW0GQR1XS
K5 cell NGXsVXlIem:5dHigbY5pcWKrdHnvckBie3OjeR?= NEfMPZZKdmirYnn0bY9vKG:oIHj1cYFvKEt3IHPlcIwh\3Kxd4ToJIlvKGFiY3XscEB3cWGkaXzpeJkh[XO|YYmsJGlEPTB;M{OuOVkyPSEQvF2= NGnyfVVUSU6JRWK=
KALS-1 cell NVPJcI1vT3Kxd4ToJIlvcGmkaYTpc44h[XO|YYm= M4fq[2lvcGmkaYTpc44hd2ZiaIXtZY4hU0GOUz2xJINmdGxiZ4Lve5RpKGmwIHGgZ4VtdCC4aXHibYxqfHliYYPzZZktKEmFNUC9NlkvOzl4OTFOwG0> M2P1PXNCVkeHUh?=
KARPAS-422 cell M1nRfWdzd3e2aDDpcohq[mm2aX;uJIF{e2G7 NXLVcIw{UW6qaXLpeIlwdiCxZjDoeY1idiCNQWLQRXMuPDJ{IHPlcIwh\3Kxd4ToJIlvKGFiY3XscEB3cWGkaXzpeJkh[XO|YYmsJGlEPTB;NEKuPVE1OiEQvF2= M{TkfXNCVkeHUh?=
KARPAS-45 cell NUDjO4FzT3Kxd4ToJIlvcGmkaYTpc44h[XO|YYm= M4LweGlvcGmkaYTpc44hd2ZiaIXtZY4hU0GUUFHTMVQ2KGOnbHyg[5Jwf3SqIHnuJIEh[2WubDD2bYFjcWyrdImgZZN{[XluIFnDOVA:PC5zMUK0O{DPxE1? Ml3BV2FPT0WU
KE-37 cell NIfleYlIem:5dHigbY5pcWKrdHnvckBie3OjeR?= NGq4WphKdmirYnn0bY9vKG:oIHj1cYFvKEuHLUO3JINmdGxiZ4Lve5RpKGmwIHGgZ4VtdCC4aXHibYxqfHliYYPzZZktKEmFNUC9PU45OzVizszN M4TlVHNCVkeHUh?=
KG-1 cell MVzHdo94fGhiaX7obYJqfGmxbjDhd5NigQ>? NEnPPZpKdmirYnn0bY9vKG:oIHj1cYFvKEuJLUGgZ4VtdCCpcn;3eIghcW5iYTDj[YxtKH[rYXLpcIl1gSCjc4PhfUwhUUN3ME2yN{46PzV5IN88US=> M3;1cnNCVkeHUh?=
KGN cell NFe3W2FIem:5dHigbY5pcWKrdHnvckBie3OjeR?= NYG0eo11UW6qaXLpeIlwdiCxZjDoeY1idiCNR16gZ4VtdCCpcn;3eIghcW5iYTDj[YxtKH[rYXLpcIl1gSCjc4PhfUwhUUN3ME2wMlU3PzR{IN88US=> M33ObHNCVkeHUh?=
KM12 cell NFPocJBIem:5dHigbY5pcWKrdHnvckBie3OjeR?= M2jVd2lvcGmkaYTpc44hd2ZiaIXtZY4hU01zMjDj[YxtKGe{b4f0bEBqdiCjIHPlcIwhfmmjYnnsbZR6KGG|c3H5MEBKSzVyPUOuOVI6PjRizszN NEf6d5JUSU6JRWK=
KMOE-2 cell M4Hzc2dzd3e2aDDpcohq[mm2aX;uJIF{e2G7 NWjkWWg6UW6qaXLpeIlwdiCxZjDoeY1idiCNTV;FMVIh[2WubDDndo94fGhiaX6gZUBk\WyuII\pZYJqdGm2eTDhd5NigSxiSVO1NF0{OC52NUS5JO69VQ>? MVfTRW5ITVJ?
KNS-42 cell M2jxUWdzd3e2aDDpcohq[mm2aX;uJIF{e2G7 NYO1ZWpZUW6qaXLpeIlwdiCxZjDoeY1idiCNTmOtOFIh[2WubDDndo94fGhiaX6gZUBk\WyuII\pZYJqdGm2eTDhd5NigSxiSVO1NF05NjhzOUG1JO69VQ>? MV7TRW5ITVJ?
KNS-81-FD cell NUjnb4RHT3Kxd4ToJIlvcGmkaYTpc44h[XO|YYm= M2C0[mlvcGmkaYTpc44hd2ZiaIXtZY4hU06VLUixMWZFKGOnbHyg[5Jwf3SqIHnuJIEh[2WubDD2bYFjcWyrdImgZZN{[XluIFnDOVA:OzdwNEK2JO69VQ>? MY\TRW5ITVJ?
KS-1 cell MkLMS5Jwf3SqIHnubIljcXSrb36gZZN{[Xl? NYfv[GpVUW6qaXLpeIlwdiCxZjDoeY1idiCNUz2xJINmdGxiZ4Lve5RpKGmwIHGgZ4VtdCC4aXHibYxqfHliYYPzZZktKEmFNUC9NE4xODR4IN88US=> MWPTRW5ITVJ?
KU812 cell NFzBSGtIem:5dHigbY5pcWKrdHnvckBie3OjeR?= NYXGdpc4UW6qaXLpeIlwdiCxZjDoeY1idiCNVUixNkBk\WyuIHfyc5d1cCCrbjDhJINmdGxidnnhZoltcXS7IHHzd4F6NCCLQ{WwQVI{NjR6NDFOwG0> NHXrbVNUSU6JRWK=
L-540 cell NHfwZlhIem:5dHigbY5pcWKrdHnvckBie3OjeR?= M4\3ZWlvcGmkaYTpc44hd2ZiaIXtZY4hVC13NECgZ4VtdCCpcn;3eIghcW5iYTDj[YxtKH[rYXLpcIl1gSCjc4PhfUwhUUN3ME2yNE44PDR3IN88US=> MXzTRW5ITVJ?
LAMA-84 cell MXXHdo94fGhiaX7obYJqfGmxbjDhd5NigQ>? M3LzcmlvcGmkaYTpc44hd2ZiaIXtZY4hVEGPQT24OEBk\WyuIHfyc5d1cCCrbjDhJINmdGxidnnhZoltcXS7IHHzd4F6NCCLQ{WwQVE{NjZ5NEKg{txO M1OxTHNCVkeHUh?=
LB1047-RCC cell NHvVOoZIem:5dHigbY5pcWKrdHnvckBie3OjeR?= Mle2TY5pcWKrdHnvckBw\iCqdX3hckBNSjFyNEetVmNEKGOnbHyg[5Jwf3SqIHnuJIEh[2WubDD2bYFjcWyrdImgZZN{[XluIFnDOVA:OjhwM{i4N{DPxE1? NH;leGtUSU6JRWK=
LB2241-RCC cell NIXWSHNIem:5dHigbY5pcWKrdHnvckBie3OjeR?= MkO5TY5pcWKrdHnvckBw\iCqdX3hckBNSjJ{NEGtVmNEKGOnbHyg[5Jwf3SqIHnuJIEh[2WubDD2bYFjcWyrdImgZZN{[XluIFnDOVA:OTBwNUWzOkDPxE1? NV6zS2x2W0GQR1XS
LB2518-MEL cell MmTaS5Jwf3SqIHnubIljcXSrb36gZZN{[Xl? NUfpTHNCUW6qaXLpeIlwdiCxZjDoeY1idiCOQkK1NVguVUWOIHPlcIwh\3Kxd4ToJIlvKGFiY3XscEB3cWGkaXzpeJkh[XO|YYmsJGlEPTB;MT63NVQ6Ps7:TR?= MmrWV2FPT0WU
LB831-BLC cell NF\4TGxIem:5dHigbY5pcWKrdHnvckBie3OjeR?= MWDJcohq[mm2aX;uJI9nKGi3bXHuJGxDQDNzLVLMR{Bk\WyuIHfyc5d1cCCrbjDhJINmdGxidnnhZoltcXS7IHHzd4F6NCCLQ{WwQVEyNjF5Mk[g{txO NWnp[lZWW0GQR1XS
LB996-RCC cell M4nNemdzd3e2aDDpcohq[mm2aX;uJIF{e2G7 M{HEXmlvcGmkaYTpc44hd2ZiaIXtZY4hVEJ7OU[tVmNEKGOnbHyg[5Jwf3SqIHnuJIEh[2WubDD2bYFjcWyrdImgZZN{[XluIFnDOVA:OTJwN{SzNUDPxE1? M{XSe3NCVkeHUh?=
LC4-1 cell Mn\sS5Jwf3SqIHnubIljcXSrb36gZZN{[Xl? M1\aVWlvcGmkaYTpc44hd2ZiaIXtZY4hVEN2LUGgZ4VtdCCpcn;3eIghcW5iYTDj[YxtKH[rYXLpcIl1gSCjc4PhfUwhUUN3ME2zNk45OzRzIN88US=> NHvwWlNUSU6JRWK=
LOUCY cell M4K3RWdzd3e2aDDpcohq[mm2aX;uJIF{e2G7 M1XMbmlvcGmkaYTpc44hd2ZiaIXtZY4hVE:XQ2mgZ4VtdCCpcn;3eIghcW5iYTDj[YxtKH[rYXLpcIl1gSCjc4PhfUwhUUN3ME2xMlE2Ojd4IN88US=> M2fLcXNCVkeHUh?=
LOXIMVI cell MX3Hdo94fGhiaX7obYJqfGmxbjDhd5NigQ>? MWfJcohq[mm2aX;uJI9nKGi3bXHuJGxQYEmPVlmgZ4VtdCCpcn;3eIghcW5iYTDj[YxtKH[rYXLpcIl1gSCjc4PhfUwhUUN3ME2zNE4zOTJ{IN88US=> NELwfodUSU6JRWK=
LS-123 cell NGPaV4hIem:5dHigbY5pcWKrdHnvckBie3OjeR?= MXHJcohq[mm2aX;uJI9nKGi3bXHuJGxUNTF{MzDj[YxtKGe{b4f0bEBqdiCjIHPlcIwhfmmjYnnsbZR6KGG|c3H5MEBKSzVyPUO5MlIzPThizszN MonYV2FPT0WU
LU-134-A cell MXzHdo94fGhiaX7obYJqfGmxbjDhd5NigQ>? MnHrTY5pcWKrdHnvckBw\iCqdX3hckBNXS1zM{StRUBk\WyuIHfyc5d1cCCrbjDhJINmdGxidnnhZoltcXS7IHHzd4F6NCCLQ{WwQVcvOTRyNkig{txO NEXSXFZUSU6JRWK=
LU-139 cell NEDUZlNIem:5dHigbY5pcWKrdHnvckBie3OjeR?= NIfONVJKdmirYnn0bY9vKG:oIHj1cYFvKEyXLUGzPUBk\WyuIHfyc5d1cCCrbjDhJINmdGxidnnhZoltcXS7IHHzd4F6NCCLQ{WwQVIzNjJzODFOwG0> MoTOV2FPT0WU
LXF-289 cell M2jDTGdzd3e2aDDpcohq[mm2aX;uJIF{e2G7 MlXXTY5pcWKrdHnvckBw\iCqdX3hckBNYEZvMki5JINmdGxiZ4Lve5RpKGmwIHGgZ4VtdCC4aXHibYxqfHliYYPzZZktKEmFNUC9NVcvPDN3Md88US=> NIL3[4xUSU6JRWK=
MC116 cell MU\Hdo94fGhiaX7obYJqfGmxbjDhd5NigQ>? MWrJcohq[mm2aX;uJI9nKGi3bXHuJG1EOTF4IHPlcIwh\3Kxd4ToJIlvKGFiY3XscEB3cWGkaXzpeJkh[XO|YYmsJGlEPTB;NEWuNFg1OSEQvF2= M{XjZ3NCVkeHUh?=
MDA-MB-134-VI cell Mn7kS5Jwf3SqIHnubIljcXSrb36gZZN{[Xl? M2TLPWlvcGmkaYTpc44hd2ZiaIXtZY4hVUSDLV3CMVE{PC2YSTDj[YxtKGe{b4f0bEBqdiCjIHPlcIwhfmmjYnnsbZR6KGG|c3H5MEBKSzVyPUO5MlI1QDZizszN NUnVPIpvW0GQR1XS
MFH-ino cell M2[3bGdzd3e2aDDpcohq[mm2aX;uJIF{e2G7 NH;FVIVKdmirYnn0bY9vKG:oIHj1cYFvKE2ISD3pco8h[2WubDDndo94fGhiaX6gZUBk\WyuII\pZYJqdGm2eTDhd5NigSxiSVO1NF0xNjZ2M{izJO69VQ>? NH;DcIRUSU6JRWK=
MHH-NB-11 cell NU\OUIVHT3Kxd4ToJIlvcGmkaYTpc44h[XO|YYm= Ml23TY5pcWKrdHnvckBw\iCqdX3hckBOUEhvTlKtNVEh[2WubDDndo94fGhiaX6gZUBk\WyuII\pZYJqdGm2eTDhd5NigSxiSVO1NF0xNjB4Nkmg{txO MUnTRW5ITVJ?
ML-2 cell NHjQd3pIem:5dHigbY5pcWKrdHnvckBie3OjeR?= Mo[4TY5pcWKrdHnvckBw\iCqdX3hckBOVC1{IHPlcIwh\3Kxd4ToJIlvKGFiY3XscEB3cWGkaXzpeJkh[XO|YYmsJGlEPTB;Mz60NFMxPCEQvF2= MXrTRW5ITVJ?
MOLT-13 cell NX\tSJkxT3Kxd4ToJIlvcGmkaYTpc44h[XO|YYm= NE\hPJVKdmirYnn0bY9vKG:oIHj1cYFvKE2RTGStNVMh[2WubDDndo94fGhiaX6gZUBk\WyuII\pZYJqdGm2eTDhd5NigSxiSVO1NF01NjR|NkWzJO69VQ>? M4DyO3NCVkeHUh?=
MOLT-16 cell MoTVS5Jwf3SqIHnubIljcXSrb36gZZN{[Xl? MXvJcohq[mm2aX;uJI9nKGi3bXHuJG1QVFRvMU[gZ4VtdCCpcn;3eIghcW5iYTDj[YxtKH[rYXLpcIl1gSCjc4PhfUwhUUN3ME20MlEyOTZ|IN88US=> M{nEWXNCVkeHUh?=
MOLT-4 cell M3HEOmdzd3e2aDDpcohq[mm2aX;uJIF{e2G7 NIDQPVZKdmirYnn0bY9vKG:oIHj1cYFvKE2RTGStOEBk\WyuIHfyc5d1cCCrbjDhJINmdGxidnnhZoltcXS7IHHzd4F6NCCLQ{WwQVE1NjRzMkSg{txO MlTXV2FPT0WU
MPP-89 cell NITnUZZIem:5dHigbY5pcWKrdHnvckBie3OjeR?= M1iyPGlvcGmkaYTpc44hd2ZiaIXtZY4hVVCSLUi5JINmdGxiZ4Lve5RpKGmwIHGgZ4VtdCC4aXHibYxqfHliYYPzZZktKEmFNUC9NU4zPTl{MjFOwG0> MWTTRW5ITVJ?
MRK-nu-1 cell M1TUOmdzd3e2aDDpcohq[mm2aX;uJIF{e2G7 MYTJcohq[mm2aX;uJI9nKGi3bXHuJG1TUy2wdT2xJINmdGxiZ4Lve5RpKGmwIHGgZ4VtdCC4aXHibYxqfHliYYPzZZktKEmFNUC9NE42PzV5MjFOwG0> NH\tR3JUSU6JRWK=
MSTO-211H cell NVv4dXdxT3Kxd4ToJIlvcGmkaYTpc44h[XO|YYm= NFHpbGhKdmirYnn0bY9vKG:oIHj1cYFvKE2VVF:tNlEyUCClZXzsJIdzd3e2aDDpckBiKGOnbHygeoli[mmuaYT5JIF{e2G7LDDJR|UxRTF{Lki2PUDPxE1? MWfTRW5ITVJ?
MV-4-11 cell NFPLS|VIem:5dHigbY5pcWKrdHnvckBie3OjeR?= MmCzTY5pcWKrdHnvckBw\iCqdX3hckBOXi12LUGxJINmdGxiZ4Lve5RpKGmwIHGgZ4VtdCC4aXHibYxqfHliYYPzZZktKEmFNUC9NE4yOzlzNTFOwG0> M1;zcXNCVkeHUh?=
NALM-6 cell NWnGTZhUT3Kxd4ToJIlvcGmkaYTpc44h[XO|YYm= NGjFV|hKdmirYnn0bY9vKG:oIHj1cYFvKE6DTF2tOkBk\WyuIHfyc5d1cCCrbjDhJINmdGxidnnhZoltcXS7IHHzd4F6NCCLQ{WwQVEvPTZzMEmg{txO NHvae3hUSU6JRWK=
NB1 cell M13tZWdzd3e2aDDpcohq[mm2aX;uJIF{e2G7 NH25NmJKdmirYnn0bY9vKG:oIHj1cYFvKE6EMTDj[YxtKGe{b4f0bEBqdiCjIHPlcIwhfmmjYnnsbZR6KGG|c3H5MEBKSzVyPUOuPFQ{PjlizszN MoThV2FPT0WU
NB10 cell Mmq5S5Jwf3SqIHnubIljcXSrb36gZZN{[Xl? M4PKWGlvcGmkaYTpc44hd2ZiaIXtZY4hVkJzMDDj[YxtKGe{b4f0bEBqdiCjIHPlcIwhfmmjYnnsbZR6KGG|c3H5MEBKSzVyPUCuNVM6OTVizszN MXLTRW5ITVJ?
NB12 cell M{DOb2dzd3e2aDDpcohq[mm2aX;uJIF{e2G7 MYTJcohq[mm2aX;uJI9nKGi3bXHuJG5DOTJiY3XscEBoem:5dHigbY4h[SClZXzsJJZq[WKrbHn0fUBie3OjeTygTWM2OD1zNj61OlU3KM7:TR?= MYfTRW5ITVJ?
NB13 cell NVTibHM4T3Kxd4ToJIlvcGmkaYTpc44h[XO|YYm= NUP1dplXUW6qaXLpeIlwdiCxZjDoeY1idiCQQkGzJINmdGxiZ4Lve5RpKGmwIHGgZ4VtdCC4aXHibYxqfHliYYPzZZktKEmFNUC9Nk4{OTJ5ODFOwG0> MnfYV2FPT0WU
NB17 cell MnLTS5Jwf3SqIHnubIljcXSrb36gZZN{[Xl? MlzHTY5pcWKrdHnvckBw\iCqdX3hckBPSjF5IHPlcIwh\3Kxd4ToJIlvKGFiY3XscEB3cWGkaXzpeJkh[XO|YYmsJGlEPTB;Mz61PFA2OSEQvF2= M4\id3NCVkeHUh?=
NB6 cell M4rrfmdzd3e2aDDpcohq[mm2aX;uJIF{e2G7 MVTJcohq[mm2aX;uJI9nKGi3bXHuJG5DPiClZXzsJIdzd3e2aDDpckBiKGOnbHygeoli[mmuaYT5JIF{e2G7LDDJR|UxRTBwNUmxNVQh|ryP NF\MRoxUSU6JRWK=
NCCIT cell NXO1U5RqT3Kxd4ToJIlvcGmkaYTpc44h[XO|YYm= NUC1c41nUW6qaXLpeIlwdiCxZjDoeY1idiCQQ1PJWEBk\WyuIHfyc5d1cCCrbjDhJINmdGxidnnhZoltcXS7IHHzd4F6NCCLQ{WwQVQyNjh2NUOg{txO NH3nTodUSU6JRWK=
NCI-H1155 cell NF;rVG1Iem:5dHigbY5pcWKrdHnvckBie3OjeR?= NXfBXlJDUW6qaXLpeIlwdiCxZjDoeY1idiCQQ1mtTFEyPTViY3XscEBoem:5dHigbY4h[SClZXzsJJZq[WKrbHn0fUBie3OjeTygTWM2OD1zND6zOFA5KM7:TR?= NF[2bWNUSU6JRWK=
NCI-H1304 cell MlzaS5Jwf3SqIHnubIljcXSrb36gZZN{[Xl? MkHDTY5pcWKrdHnvckBw\iCqdX3hckBPS0lvSEGzNFQh[2WubDDndo94fGhiaX6gZUBk\WyuII\pZYJqdGm2eTDhd5NigSxiSVO1NF0yOS56OUiyJO69VQ>? MVHTRW5ITVJ?
NCI-H1355 cell MXLHdo94fGhiaX7obYJqfGmxbjDhd5NigQ>? MV\Jcohq[mm2aX;uJI9nKGi3bXHuJG5EUS2KMUO1OUBk\WyuIHfyc5d1cCCrbjDhJINmdGxidnnhZoltcXS7IHHzd4F6NCCLQ{WwQVQvQTRzMTFOwG0> MmPuV2FPT0WU
NCI-H1395 cell NX:yUYEzT3Kxd4ToJIlvcGmkaYTpc44h[XO|YYm= MonMTY5pcWKrdHnvckBw\iCqdX3hckBPS0lvSEGzPVUh[2WubDDndo94fGhiaX6gZUBk\WyuII\pZYJqdGm2eTDhd5NigSxiSVO1NF0zOi56N{m1JO69VQ>? NVjVWmxFW0GQR1XS
NCI-H1417 cell M2LvOmdzd3e2aDDpcohq[mm2aX;uJIF{e2G7 NH;IXJhKdmirYnn0bY9vKG:oIHj1cYFvKE6FST3INVQyPyClZXzsJIdzd3e2aDDpckBiKGOnbHygeoli[mmuaYT5JIF{e2G7LDDJR|UxRTVwNke1NlIh|ryP MnL3V2FPT0WU
NCI-H1436 cell NUT0dZFHT3Kxd4ToJIlvcGmkaYTpc44h[XO|YYm= MU\Jcohq[mm2aX;uJI9nKGi3bXHuJG5EUS2KMUSzOkBk\WyuIHfyc5d1cCCrbjDhJINmdGxidnnhZoltcXS7IHHzd4F6NCCLQ{WwQVMvQDRzMEGg{txO MkjqV2FPT0WU
NTERA-S-cl-D1 cell NXnjPFB5T3Kxd4ToJIlvcGmkaYTpc44h[XO|YYm= MlHZTY5pcWKrdHnvckBw\iCqdX3hckBPXEWUQT3TMYNtNURzIHPlcIwh\3Kxd4ToJIlvKGFiY3XscEB3cWGkaXzpeJkh[XO|YYmsJGlEPTB;MUKuPFk{PSEQvF2= M3vCW3NCVkeHUh?=
JiyoyeP-2003 cell NXq3bpRnT3Kxd4ToJIlvcGmkaYTpc44h[XO|YYm= MnHxTY5pcWKrdHnvckBw\iCqdX3hckBLcXmxeXXQMVIxODNiY3XscEBoem:5dHigbY4h[SClZXzsJJZq[WKrbHn0fUBie3OjeTygTWM2OD1|Nj62Nlg1KM7:TR?= MV\TRW5ITVJ?

... Click to View More Cell Line Experimental Data

In vivo Oral administration of GSK269962A produced a profound dose-dependent reduction of systemic blood pressure in spontaneously hypertensive rats. The reduction of blood pressure was acute and substantial. The maximal effect on blood pressure was observed approximately 2 h after oral gavages. The reduction of blood pressure was accompanied by an acute, dose-dependent increase in heart rate, presumably due to the activation of baroreflex mechanism[1]. ROCK inhibition with the use of GSK 269962 in the 10 mg/kg dose, in turn, triggered an increase in VV(voided volume), PVR(post-void residual), VT(volume threshold), VE(voiding efficiency), ICI(intercontraction interval), BC(bladder compliance), and VTNVC(volume threshold to elicit NVC). The inhibition of the ROCK pathway through GSK 269962 appeared to have no effect on either HR(heart rate), SBP(systolic blood pressure), MBP(systolic blood pressure), or DBP(diastolic blood pressure)[2]. NVC:nonvoiding contractions.

Protocol

Cell Research:[1]
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  • Cell lines: Human primary smooth muscle cells
  • Concentrations: 3 μM
  • Incubation Time: 150 min
  • Method: Human primary smooth muscle cells were serum-starved(cells were grown on coverslips, and at approximately 50% confluence, they were serum-starved overnight) and stimulated with AngII (100 nM) for 2 h. ROCK inhibitors (3 μM for SB-772077-B or GSK269962A) were added 30 min before AngII stimulation, and cells were fixed and stained with rhodamine phalloidin. Confocal images of actin stain were obtained.
    (Only for Reference)
Animal Research:[2]
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  • Animal Models: female Wistar rats
  • Formulation: saline
  • Dosages: 5 or 10 mg/kg
  • Administration: intra-arterially
    (Only for Reference)

Solubility (25°C)

In vitro DMSO 100 mg/mL (164.72 mM)
Ethanol 6 mg/mL (9.88 mM)
Water Insoluble

* Please note that Selleck tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.

Chemical Information

Molecular Weight 607.06
Formula

C29H30N8O5.HCl

CAS No. 850664-21-0(free base)
Storage powder
in solvent
Synonyms GSK269962B, GSK269962, GSK 269962

Bio Calculators

Molarity Calculator

Molarity Calculator

Calculate the mass, volume or concentration required for a solution. The Selleck molarity calculator is based on the following equation:

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

  • Mass
    Concentration
    Volume
    Molecular Weight

*When preparing stock solutions, please always use the batch-specific molecular weight of the product found on the via label and MSDS / COA (available on product pages).

Dilution Calculator

Dilution Calculator

Calculate the dilution required to prepare a stock solution. The Selleck dilution calculator is based on the following equation:

Concentration (start) x Volume (start) = Concentration (final) x Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2 ( Input Output )

  • C1
    V1
    C2
    V2

* When preparing stock solutions always use the batch-specific molecular weight of the product found on the vial label and MSDS / COA (available online).

The Serial Dilution Calculator Equation

  • Serial Dilutions

  • Computed Result

  • C1=C0/X C1: LOG(C1):
    C2=C1/X C2: LOG(C2):
    C3=C2/X C3: LOG(C3):
    C4=C3/X C4: LOG(C4):
    C5=C4/X C5: LOG(C5):
    C6=C5/X C6: LOG(C6):
    C7=C6/X C7: LOG(C7):
    C8=C7/X C8: LOG(C8):
Molecular Weight Calculator

Molecular Weight Calculator

Enter the chemical formula of a compound to calculate its molar mass and elemental composition:

Total Molecular Weight: g/mol

Tip: Chemical formula is case sensitive. C10H16N2O2 c10h16n2o2

Instructions to calculate molar mass (molecular weight) of a chemical compound:

To calculate molar mass of a chemical compound, please enter its chemical formula and click 'Calculate'.

Definitions of molecular mass, molecular weight, molar mass and molar weight:

Molecular mass (molecular weight) is the mass of one molecule of a substance and is expressed in the unified atomic mass units (u). (1 u is equal to 1/12 the mass of one atom of carbon-12)
Molar mass (molar weight) is the mass of one mole of a substance and is expressed in g/mol.

Molarity Calculator

Mass Concentration Volume Molecular Weight

Tech Support

Answers to questions you may have can be found in the inhibitor handling instructions. Topics include how to prepare stock solutions, how to store inhibitors, and issues that need special attention for cell-based assays and animal experiments.

Handling Instructions

Tel: +1-832-582-8158 Ext:3

If you have any other enquiries, please leave a message.

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ROCK Signaling Pathway Map

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Cell Lines Assay Type Concentration Incubation Time Formulation Activity Description PMID