GSK269962A HCl

Catalog No.S7687 Synonyms: GSK269962B, GSK269962, GSK 269962

GSK269962A HCl Chemical Structure

Molecular Weight(MW): 607.06

GSK269962 is a selective ROCK(Rho-associated protein kinase) inhibitor with IC50 values of 1.6 and 4 nM for ROCK1 and ROCK2, respectively.

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Purity & Quality Control

Choose Selective ROCK Inhibitors

Biological Activity

Description GSK269962 is a selective ROCK(Rho-associated protein kinase) inhibitor with IC50 values of 1.6 and 4 nM for ROCK1 and ROCK2, respectively.
Targets
ROCK1 [1]
(Cell-free assay)
ROCK2 [1]
(Cell-free assay)
MSK1 [1]
(Cell-free assay)
RSK1 [1]
(Cell-free assay)
1.6 nM 4 nM 49 nM 132 nM
In vitro

GSK269962A completely abolished the actin stress fiber formation induced by angiotensin II in human smooth muscles. Such suppressive effect on actin fiber formation was observed beginning at around 1 μM GSK269962A. GSK269962A induced vasorelaxation in preconstricted rat aorta(tissue baths) with an IC50 of 35 nM. the relaxation induced by GSK269962A is reversible. GSK269962A suppressed IL-6 mRNA transcription and reduced LPS-induced IL-6 and TNF-α protein production in macrophages[1].

Cell Data
Cell Lines Assay Type Concentration Incubation Time Formulation Activity Description PMID
NCI-H1581 MYLHdo94fGhiaX7obYJqfGmxbjDhd5NigQ>? MUXJcohq[mm2aX;uJI9nKGi3bXHuJG5EUS2KMUW4NUBk\WyuIHfyc5d1cCCrbjDhJINmdGxidnnhZoltcXS7IHHzd4F6NCCLQ{WwQVE5Njh2N{eg{txO MmTEV2FPT0WU
NCI-H1694 MkL0S5Jwf3SqIHnubIljcXSrb36gZZN{[Xl? M{\5e2lvcGmkaYTpc44hd2ZiaIXtZY4hVkOLLVixOlk1KGOnbHyg[5Jwf3SqIHnuJIEh[2WubDD2bYFjcWyrdImgZZN{[XluIFnDOVA:OjRwOEe0PUDPxE1? NIPyW2pUSU6JRWK=
NCI-H1963 NX[2c2llT3Kxd4ToJIlvcGmkaYTpc44h[XO|YYm= M3[4O2lvcGmkaYTpc44hd2ZiaIXtZY4hVkOLLVixPVY{KGOnbHyg[5Jwf3SqIHnuJIEh[2WubDD2bYFjcWyrdImgZZN{[XluIFnDOVA:OS5{N{izPUDPxE1? M1rCS3NCVkeHUh?=
NCI-H2081 NYn5NppST3Kxd4ToJIlvcGmkaYTpc44h[XO|YYm= M1\IeGlvcGmkaYTpc44hd2ZiaIXtZY4hVkOLLViyNFgyKGOnbHyg[5Jwf3SqIHnuJIEh[2WubDD2bYFjcWyrdImgZZN{[XluIFnDOVA:OzRwNkC0OEDPxE1? M1HM[XNCVkeHUh?=
NCI-H209 NH\PSJNIem:5dHigbY5pcWKrdHnvckBie3OjeR?= M2jKO2lvcGmkaYTpc44hd2ZiaIXtZY4hVkOLLViyNFkh[2WubDDndo94fGhiaX6gZUBk\WyuII\pZYJqdGm2eTDhd5NigSxiSVO1NF0zOi54MkeyJO69VQ>? Ml3RV2FPT0WU
NCI-H2107 NEe2VWNIem:5dHigbY5pcWKrdHnvckBie3OjeR?= MoDJTY5pcWKrdHnvckBw\iCqdX3hckBPS0lvSEKxNFch[2WubDDndo94fGhiaX6gZUBk\WyuII\pZYJqdGm2eTDhd5NigSxiSVO1NF0zPS54NU[xJO69VQ>? MnTQV2FPT0WU
NCI-H2126 M3PZ[Gdzd3e2aDDpcohq[mm2aX;uJIF{e2G7 M{[1VmlvcGmkaYTpc44hd2ZiaIXtZY4hVkOLLViyNVI3KGOnbHyg[5Jwf3SqIHnuJIEh[2WubDD2bYFjcWyrdImgZZN{[XluIFnDOVA:Pi53MESyOkDPxE1? NWKzfopUW0GQR1XS
NCI-H2171 M2rkbGdzd3e2aDDpcohq[mm2aX;uJIF{e2G7 NXTrdWdHUW6qaXLpeIlwdiCxZjDoeY1idiCQQ1mtTFIyPzFiY3XscEBoem:5dHigbY4h[SClZXzsJJZq[WKrbHn0fUBie3OjeTygTWM2OD1yLkm1PVM4KM7:TR?= NEK1XFBUSU6JRWK=
NCI-H2227 NGXYVpBIem:5dHigbY5pcWKrdHnvckBie3OjeR?= M{HoSGlvcGmkaYTpc44hd2ZiaIXtZY4hVkOLLViyNlI4KGOnbHyg[5Jwf3SqIHnuJIEh[2WubDD2bYFjcWyrdImgZZN{[XluIFnDOVA:Py56OE[xOkDPxE1? MnW5V2FPT0WU
NCI-H524 NHvnfFRIem:5dHigbY5pcWKrdHnvckBie3OjeR?= MlfFTY5pcWKrdHnvckBw\iCqdX3hckBPS0lvSEWyOEBk\WyuIHfyc5d1cCCrbjDhJINmdGxidnnhZoltcXS7IHHzd4F6NCCLQ{WwQVIzNjh5NkOg{txO NH:0VmdUSU6JRWK=
NCI-H526 MW\Hdo94fGhiaX7obYJqfGmxbjDhd5NigQ>? MnS3TY5pcWKrdHnvckBw\iCqdX3hckBPS0lvSEWyOkBk\WyuIHfyc5d1cCCrbjDhJINmdGxidnnhZoltcXS7IHHzd4F6NCCLQ{WwQVE5NjV2M{Gg{txO NV;mS4trW0GQR1XS
NCI-H720 M2r2UWdzd3e2aDDpcohq[mm2aX;uJIF{e2G7 MnP1TY5pcWKrdHnvckBw\iCqdX3hckBPS0lvSEeyNEBk\WyuIHfyc5d1cCCrbjDhJINmdGxidnnhZoltcXS7IHHzd4F6NCCLQ{WwQVIvPDVzNkGg{txO M4j3e3NCVkeHUh?=
NMC-G1 MYPHdo94fGhiaX7obYJqfGmxbjDhd5NigQ>? M{\STmlvcGmkaYTpc44hd2ZiaIXtZY4hVk2FLVexJINmdGxiZ4Lve5RpKGmwIHGgZ4VtdCC4aXHibYxqfHliYYPzZZktKEmFNUC9NVUvODV5ODFOwG0> MX;TRW5ITVJ?
NOS-1 cell M2HuNWdzd3e2aDDpcohq[mm2aX;uJIF{e2G7 MlnnTY5pcWKrdHnvckBw\iCqdX3hckBPV1NvMTDj[YxtKGe{b4f0bEBqdiCjIHPlcIwhfmmjYnnsbZR6KGG|c3H5MEBKSzVyPUWuPFIzQTRizszN Mly2V2FPT0WU
OCI-AML2 cell MXjHdo94fGhiaX7obYJqfGmxbjDhd5NigQ>? MkP2TY5pcWKrdHnvckBw\iCqdX3hckBQS0lvQV3MNkBk\WyuIHfyc5d1cCCrbjDhJINmdGxidnnhZoltcXS7IHHzd4F6NCCLQ{WwQVExNjl2OU[g{txO Mo\IV2FPT0WU
OCUB-M cell NHvVSGhIem:5dHigbY5pcWKrdHnvckBie3OjeR?= Mn7yTY5pcWKrdHnvckBw\iCqdX3hckBQS1WELV2gZ4VtdCCpcn;3eIghcW5iYTDj[YxtKH[rYXLpcIl1gSCjc4PhfUwhUUN3ME2xO{4zODFizszN MnvSV2FPT0WU
ONS-76 cell NFH3S5FIem:5dHigbY5pcWKrdHnvckBie3OjeR?= Ml74TY5pcWKrdHnvckBw\iCqdX3hckBQVlNvN{[gZ4VtdCCpcn;3eIghcW5iYTDj[YxtKH[rYXLpcIl1gSCjc4PhfUwhUUN3ME2xN{46OTlzIN88US=> MnK0V2FPT0WU
OS-RC-2 cell MmLCS5Jwf3SqIHnubIljcXSrb36gZZN{[Xl? MVjJcohq[mm2aX;uJI9nKGi3bXHuJG9UNVKFLUKgZ4VtdCCpcn;3eIghcW5iYTDj[YxtKH[rYXLpcIl1gSCjc4PhfUwhUUN3ME20Ok4yQTVizszN MVfTRW5ITVJ?
OVCAR-4 cell MUXHdo94fGhiaX7obYJqfGmxbjDhd5NigQ>? MVvJcohq[mm2aX;uJI9nKGi3bXHuJG9XS0GULUSgZ4VtdCCpcn;3eIghcW5iYTDj[YxtKH[rYXLpcIl1gSCjc4PhfUwhUUN3ME24MlcyQDB6IN88US=> MnHmV2FPT0WU
P30-OHK cell MYLHdo94fGhiaX7obYJqfGmxbjDhd5NigQ>? M1HFcmlvcGmkaYTpc44hd2ZiaIXtZY4hWDNyLV;IT{Bk\WyuIHfyc5d1cCCrbjDhJINmdGxidnnhZoltcXS7IHHzd4F6NCCLQ{WwQVcvPjJ6N{eg{txO MXnTRW5ITVJ?
P30-OHK cell NXfzZ|dtT3Kxd4ToJIlvcGmkaYTpc44h[XO|YYm= MmjzTY5pcWKrdHnvckBw\iCqdX3hckBRTi1|OEKgZ4VtdCCpcn;3eIghcW5iYTDj[YxtKH[rYXLpcIl1gSCjc4PhfUwhUUN3ME23MlA1QTV2IN88US=> MnfJV2FPT0WU
PSN1 cell M1m0OWdzd3e2aDDpcohq[mm2aX;uJIF{e2G7 NVzmXmNUUW6qaXLpeIlwdiCxZjDoeY1idiCSU16xJINmdGxiZ4Lve5RpKGmwIHGgZ4VtdCC4aXHibYxqfHliYYPzZZktKEmFNUC9Ok4zOjF{NjFOwG0> MnzKV2FPT0WU
QIMR-WIL cell M2q0Nmdzd3e2aDDpcohq[mm2aX;uJIF{e2G7 MX\Jcohq[mm2aX;uJI9nKGi3bXHuJHFKVVJvV1nMJINmdGxiZ4Lve5RpKGmwIHGgZ4VtdCC4aXHibYxqfHliYYPzZZktKEmFNUC9NE41QTByNDFOwG0> MnPBV2FPT0WU
RCC10RGB cell MWXHdo94fGhiaX7obYJqfGmxbjDhd5NigQ>? NHezd|JKdmirYnn0bY9vKG:oIHj1cYFvKFKFQ{GwVmdDKGOnbHyg[5Jwf3SqIHnuJIEh[2WubDD2bYFjcWyrdImgZZN{[XluIFnDOVA:OThwOUCzOkDPxE1? NXH5NnhNW0GQR1XS
RKO cell NGn3UHJIem:5dHigbY5pcWKrdHnvckBie3OjeR?= NXv5PY1ZUW6qaXLpeIlwdiCxZjDoeY1idiCUS1:gZ4VtdCCpcn;3eIghcW5iYTDj[YxtKH[rYXLpcIl1gSCjc4PhfUwhUUN3ME2xNE42PjZ{IN88US=> M3XTU3NCVkeHUh?=
RL95-2 cell MYPHdo94fGhiaX7obYJqfGmxbjDhd5NigQ>? MYXJcohq[mm2aX;uJI9nKGi3bXHuJHJNQTVvMjDj[YxtKGe{b4f0bEBqdiCjIHPlcIwhfmmjYnnsbZR6KGG|c3H5MEBKSzVyPUGwMlY4KM7:TR?= NIHqN3pUSU6JRWK=
RPMI-6666 cell M3naTmdzd3e2aDDpcohq[mm2aX;uJIF{e2G7 MXnJcohq[mm2aX;uJI9nKGi3bXHuJHJRVUlvNk[2OkBk\WyuIHfyc5d1cCCrbjDhJINmdGxidnnhZoltcXS7IHHzd4F6NCCLQ{WwQVE5NjV{M{[g{txO NFzRUndUSU6JRWK=
RPMI-8402 cell NVPybGZxT3Kxd4ToJIlvcGmkaYTpc44h[XO|YYm= NHfUeItKdmirYnn0bY9vKG:oIHj1cYFvKFKSTVmtPFQxOiClZXzsJIdzd3e2aDDpckBiKGOnbHygeoli[mmuaYT5JIF{e2G7LDDJR|UxRTRwNUi1OkDPxE1? M1y2ZXNCVkeHUh?=
RXF393 cell M362Vmdzd3e2aDDpcohq[mm2aX;uJIF{e2G7 MXrJcohq[mm2aX;uJI9nKGi3bXHuJHJZTjN7MzDj[YxtKGe{b4f0bEBqdiCjIHPlcIwhfmmjYnnsbZR6KGG|c3H5MEBKSzVyPUCuN|k{KM7:TR?= MkfZV2FPT0WU
Ramos-2G6-4C10 cell NIPWdZJIem:5dHigbY5pcWKrdHnvckBie3OjeR?= MmXyTY5pcWKrdHnvckBw\iCqdX3hckBT[W2xcz2yS|YuPENzMDDj[YxtKGe{b4f0bEBqdiCjIHPlcIwhfmmjYnnsbZR6KGG|c3H5MEBKSzVyPUGuN|U4KM7:TR?= NHf1d3hUSU6JRWK=
SCLC-21H cell M{DmW2dzd3e2aDDpcohq[mm2aX;uJIF{e2G7 NV3odlVbUW6qaXLpeIlwdiCxZjDoeY1idiCVQ1zDMVIyUCClZXzsJIdzd3e2aDDpckBiKGOnbHygeoli[mmuaYT5JIF{e2G7LDDJR|UxRTdwNkGxOFkh|ryP NIjrdZFUSU6JRWK=
SF126 cell NWL2W4N2T3Kxd4ToJIlvcGmkaYTpc44h[XO|YYm= MVTJcohq[mm2aX;uJI9nKGi3bXHuJHNHOTJ4IHPlcIwh\3Kxd4ToJIlvKGFiY3XscEB3cWGkaXzpeJkh[XO|YYmsJGlEPTB;MUGuPFMzOc7:TR?= NULyVph4W0GQR1XS
SF268 cell NEXkbm1Iem:5dHigbY5pcWKrdHnvckBie3OjeR?= M2HkRmlvcGmkaYTpc44hd2ZiaIXtZY4hW0Z{NkigZ4VtdCCpcn;3eIghcW5iYTDj[YxtKH[rYXLpcIl1gSCjc4PhfUwhUUN3ME22MlI{OTh|IN88US=> M1\LV3NCVkeHUh?=
SF539 cell NH\NVmNIem:5dHigbY5pcWKrdHnvckBie3OjeR?= M4rnWmlvcGmkaYTpc44hd2ZiaIXtZY4hW0Z3M{mgZ4VtdCCpcn;3eIghcW5iYTDj[YxtKH[rYXLpcIl1gSCjc4PhfUwhUUN3ME2xMlI5PjZzIN88US=> M1[5XXNCVkeHUh?=
SH-4 cell MUPHdo94fGhiaX7obYJqfGmxbjDhd5NigQ>? MmPVTY5pcWKrdHnvckBw\iCqdX3hckBUUC12IHPlcIwh\3Kxd4ToJIlvKGFiY3XscEB3cWGkaXzpeJkh[XO|YYmsJGlEPTB;NT63OVUxQCEQvF2= NH7id3pUSU6JRWK=
SIG-M5 cell M{fsfmdzd3e2aDDpcohq[mm2aX;uJIF{e2G7 MlntTY5pcWKrdHnvckBw\iCqdX3hckBUUUdvTUWgZ4VtdCCpcn;3eIghcW5iYTDj[YxtKH[rYXLpcIl1gSCjc4PhfUwhUUN3ME2xNU44OjV7IN88US=> M1LEU3NCVkeHUh?=
SJSA-1 cell MkGyS5Jwf3SqIHnubIljcXSrb36gZZN{[Xl? MWDJcohq[mm2aX;uJI9nKGi3bXHuJHNLW0FvMTDj[YxtKGe{b4f0bEBqdiCjIHPlcIwhfmmjYnnsbZR6KGG|c3H5MEBKSzVyPUGuNFQ2OjZizszN Mm\CV2FPT0WU
SK-LMS-1 cell M3K4R2dzd3e2aDDpcohq[mm2aX;uJIF{e2G7 M3HyOGlvcGmkaYTpc44hd2ZiaIXtZY4hW0tvTF3TMVEh[2WubDDndo94fGhiaX6gZUBk\WyuII\pZYJqdGm2eTDhd5NigSxiSVO1NF0{Oi53OU[1JO69VQ>? MmDyV2FPT0WU
SK-MM-2 cell MkO3S5Jwf3SqIHnubIljcXSrb36gZZN{[Xl? MWLJcohq[mm2aX;uJI9nKGi3bXHuJHNMNU2PLUKgZ4VtdCCpcn;3eIghcW5iYTDj[YxtKH[rYXLpcIl1gSCjc4PhfUwhUUN3ME20Nk4{PDB3IN88US=> MoW0V2FPT0WU
SK-N-DZ cell MXHHdo94fGhiaX7obYJqfGmxbjDhd5NigQ>? MVTJcohq[mm2aX;uJI9nKGi3bXHuJHNMNU5vRGqgZ4VtdCCpcn;3eIghcW5iYTDj[YxtKH[rYXLpcIl1gSCjc4PhfUwhUUN3ME25MlQ5OzF2IN88US=> M{i0fHNCVkeHUh?=
SK-NEP-1 cell NGfFcm1Iem:5dHigbY5pcWKrdHnvckBie3OjeR?= MV7Jcohq[mm2aX;uJI9nKGi3bXHuJHNMNU6HUD2xJINmdGxiZ4Lve5RpKGmwIHGgZ4VtdCC4aXHibYxqfHliYYPzZZktKEmFNUC9NVcvPTR3NjFOwG0> NFnjWmlUSU6JRWK=
SK-PN-DW cell NILlWYlIem:5dHigbY5pcWKrdHnvckBie3OjeR?= NUTyeG9jUW6qaXLpeIlwdiCxZjDoeY1idiCVSz3QUk1FXyClZXzsJIdzd3e2aDDpckBiKGOnbHygeoli[mmuaYT5JIF{e2G7LDDJR|UxRTJ2Lkm3N|Yh|ryP MoPwV2FPT0WU
SNB75 cell M4rVcGdzd3e2aDDpcohq[mm2aX;uJIF{e2G7 NV33VlZTUW6qaXLpeIlwdiCxZjDoeY1idiCVTlK3OUBk\WyuIHfyc5d1cCCrbjDhJINmdGxidnnhZoltcXS7IHHzd4F6NCCLQ{WwQVgvODd5M{eg{txO M{H4WnNCVkeHUh?=
SR cell Mk[1S5Jwf3SqIHnubIljcXSrb36gZZN{[Xl? MlH0TY5pcWKrdHnvckBw\iCqdX3hckBUWiClZXzsJIdzd3e2aDDpckBiKGOnbHygeoli[mmuaYT5JIF{e2G7LDDJR|UxRTBwMECwNVM4KM7:TR?= MX\TRW5ITVJ?
SU-DHL-1 cell NXXuU|lIT3Kxd4ToJIlvcGmkaYTpc44h[XO|YYm= MnnpTY5pcWKrdHnvckBw\iCqdX3hckBUXS2GSFytNUBk\WyuIHfyc5d1cCCrbjDhJINmdGxidnnhZoltcXS7IHHzd4F6NCCLQ{WwQVEzNjd|M{[g{txO MlP3V2FPT0WU
SW684 cell MUnHdo94fGhiaX7obYJqfGmxbjDhd5NigQ>? NV7reHd1UW6qaXLpeIlwdiCxZjDoeY1idiCVV{[4OEBk\WyuIHfyc5d1cCCrbjDhJINmdGxidnnhZoltcXS7IHHzd4F6NCCLQ{WwQVM6NjBzMTFOwG0> MV7TRW5ITVJ?
SW872 cell M3[xeGdzd3e2aDDpcohq[mm2aX;uJIF{e2G7 M2TvVmlvcGmkaYTpc44hd2ZiaIXtZY4hW1d6N{KgZ4VtdCCpcn;3eIghcW5iYTDj[YxtKH[rYXLpcIl1gSCjc4PhfUwhUUN3ME2wMlg5PjV4IN88US=> NVuwblFrW0GQR1XS
SW962 cell NUnmN3pNT3Kxd4ToJIlvcGmkaYTpc44h[XO|YYm= NFH3[HRKdmirYnn0bY9vKG:oIHj1cYFvKFOZOU[yJINmdGxiZ4Lve5RpKGmwIHGgZ4VtdCC4aXHibYxqfHliYYPzZZktKEmFNUC9NVIvPzV{MTFOwG0> MVnTRW5ITVJ?
697 cell NGe1UINIem:5dHigbY5pcWKrdHnvckBie3OjeR?= NETjUHNKdmirYnn0bY9vKG:oIHj1cYFvKDZ7NzDj[YxtKGe{b4f0bEBqdiCjIHPlcIwhfmmjYnnsbZR6KGG|c3H5MEBKSzVyPUCuNlk6OSEQvF2= NY\xdVlQW0GQR1XS
8-MG-BA cell MlvtS5Jwf3SqIHnubIljcXSrb36gZZN{[Xl? NUKwUmU{UW6qaXLpeIlwdiCxZjDoeY1idiB6LV3HMWJCKGOnbHyg[5Jwf3SqIHnuJIEh[2WubDD2bYFjcWyrdImgZZN{[XluIFnDOVA:OjNwMEe5N{DPxE1? NWfvT|RoW0GQR1XS
A101D cell NHjaVWxIem:5dHigbY5pcWKrdHnvckBie3OjeR?= MYPJcohq[mm2aX;uJI9nKGi3bXHuJGEyODGGIHPlcIwh\3Kxd4ToJIlvKGFiY3XscEB3cWGkaXzpeJkh[XO|YYmsJGlEPTB;MT64O|A{PCEQvF2= NGXucItUSU6JRWK=
ACN cell MUnHdo94fGhiaX7obYJqfGmxbjDhd5NigQ>? NV\zTVhbUW6qaXLpeIlwdiCxZjDoeY1idiCDQ16gZ4VtdCCpcn;3eIghcW5iYTDj[YxtKH[rYXLpcIl1gSCjc4PhfUwhUUN3ME2yNU41Ozh5IN88US=> M4n0NXNCVkeHUh?=
AM-38 cell MlzuS5Jwf3SqIHnubIljcXSrb36gZZN{[Xl? NVHsd5BFUW6qaXLpeIlwdiCxZjDoeY1idiCDTT2zPEBk\WyuIHfyc5d1cCCrbjDhJINmdGxidnnhZoltcXS7IHHzd4F6NCCLQ{WwQVcvOjZ|Mkeg{txO M3XzNnNCVkeHUh?=
ATN-1 cell NWf0[2pOT3Kxd4ToJIlvcGmkaYTpc44h[XO|YYm= MXXJcohq[mm2aX;uJI9nKGi3bXHuJGFVVi1zIHPlcIwh\3Kxd4ToJIlvKGFiY3XscEB3cWGkaXzpeJkh[XO|YYmsJGlEPTB;MkSuO|U2PSEQvF2= NF2xR2ZUSU6JRWK=
BB30-HNC cell NInReVZIem:5dHigbY5pcWKrdHnvckBie3OjeR?= MnHETY5pcWKrdHnvckBw\iCqdX3hckBDSjNyLVjOR{Bk\WyuIHfyc5d1cCCrbjDhJINmdGxidnnhZoltcXS7IHHzd4F6NCCLQ{WwQVIzNjJ3M{Kg{txO MX7TRW5ITVJ?
BB49-HNC cell M3jsZmdzd3e2aDDpcohq[mm2aX;uJIF{e2G7 NHXEOHJKdmirYnn0bY9vKG:oIHj1cYFvKEKENEmtTG5EKGOnbHyg[5Jwf3SqIHnuJIEh[2WubDD2bYFjcWyrdImgZZN{[XluIFnDOVA:OC5yMEe4PUDPxE1? NFXDUGpUSU6JRWK=
human BC-1 cell M3TVOWdzd3e2aDDpcohq[mm2aX;uJIF{e2G7 NWTSbJVxUW6qaXLpeIlwdiCxZjDoeY1idiCEQz2xJINmdGxiZ4Lve5RpKGmwIHGgZ4VtdCC4aXHibYxqfHliYYPzZZktKEmFNUC9N{46PzFyNzFOwG0> NGPTcopUSU6JRWK=
BE-13 cell NF[4WGJIem:5dHigbY5pcWKrdHnvckBie3OjeR?= MnXuTY5pcWKrdHnvckBw\iCqdX3hckBDTS1zMzDj[YxtKGe{b4f0bEBqdiCjIHPlcIwhfmmjYnnsbZR6KGG|c3H5MEBKSzVyPUCuNVQxQDIQvF2= MX;TRW5ITVJ?
BL-70 cell NX\GUGR{T3Kxd4ToJIlvcGmkaYTpc44h[XO|YYm= NIe3c3hKdmirYnn0bY9vKG:oIHj1cYFvKEKOLUewJINmdGxiZ4Lve5RpKGmwIHGgZ4VtdCC4aXHibYxqfHliYYPzZZktKEmFNUC9N{41ODdyMzFOwG0> M2PwbnNCVkeHUh?=
BV-173 cell MU\Hdo94fGhiaX7obYJqfGmxbjDhd5NigQ>? NGPZVWxKdmirYnn0bY9vKG:oIHj1cYFvKEKYLUG3N{Bk\WyuIHfyc5d1cCCrbjDhJINmdGxidnnhZoltcXS7IHHzd4F6NCCLQ{WwQVE5Njh6NUmg{txO M1mw[nNCVkeHUh?=
Becker cell NYCwfmw{T3Kxd4ToJIlvcGmkaYTpc44h[XO|YYm= NU\NeVB5UW6qaXLpeIlwdiCxZjDoeY1idiCEZXPr[ZIh[2WubDDndo94fGhiaX6gZUBk\WyuII\pZYJqdGm2eTDhd5NigSxiSVO1NF0yOy57NUS1JO69VQ>? NXfEN|ZNW0GQR1XS
CAL-148 cell MX3Hdo94fGhiaX7obYJqfGmxbjDhd5NigQ>? NUH5[oJ[UW6qaXLpeIlwdiCxZjDoeY1idiCFQVytNVQ5KGOnbHyg[5Jwf3SqIHnuJIEh[2WubDD2bYFjcWyrdImgZZN{[XluIFnDOVA:OzVwNkW1O{DPxE1? NV30XWNEW0GQR1XS
TE-10 cell NIXMZZlIem:5dHigbY5pcWKrdHnvckBie3OjeR?= MlO2TY5pcWKrdHnvckBw\iCqdX3hckBVTS1zMDDj[YxtKGe{b4f0bEBqdiCjIHPlcIwhfmmjYnnsbZR6KGG|c3H5MEBKSzVyPUKyMlg1OjNizszN MlzEV2FPT0WU
TE-12 cell NHz3b21Iem:5dHigbY5pcWKrdHnvckBie3OjeR?= M{nZc2lvcGmkaYTpc44hd2ZiaIXtZY4hXEVvMUKgZ4VtdCCpcn;3eIghcW5iYTDj[YxtKH[rYXLpcIl1gSCjc4PhfUwhUUN3ME2zNk41OTF2IN88US=> MUjTRW5ITVJ?
TE-8 cell NUXi[2VUT3Kxd4ToJIlvcGmkaYTpc44h[XO|YYm= MV7Jcohq[mm2aX;uJI9nKGi3bXHuJHRGNThiY3XscEBoem:5dHigbY4h[SClZXzsJJZq[WKrbHn0fUBie3OjeTygTWM2OD1zMT62NFg6KM7:TR?= NIm2bGVUSU6JRWK=
TE-9 cell NHLQfJpIem:5dHigbY5pcWKrdHnvckBie3OjeR?= NYnkW|NxUW6qaXLpeIlwdiCxZjDoeY1idiCWRT25JINmdGxiZ4Lve5RpKGmwIHGgZ4VtdCC4aXHibYxqfHliYYPzZZktKEmFNUC9N|YvPjN6MTFOwG0> NF35PIpUSU6JRWK=
TGW cell NUHtUpdnT3Kxd4ToJIlvcGmkaYTpc44h[XO|YYm= M2H0bmlvcGmkaYTpc44hd2ZiaIXtZY4hXEeZIHPlcIwh\3Kxd4ToJIlvKGFiY3XscEB3cWGkaXzpeJkh[XO|YYmsJGlEPTB;MkOuN|U4PyEQvF2= MV\TRW5ITVJ?
UACC-257 cell NGrkcIxIem:5dHigbY5pcWKrdHnvckBie3OjeR?= M{jCRWlvcGmkaYTpc44hd2ZiaIXtZY4hXUGFQz2yOVch[2WubDDndo94fGhiaX6gZUBk\WyuII\pZYJqdGm2eTDhd5NigSxiSVO1NF05NjdyNkK1JO69VQ>? NFHETYlUSU6JRWK=
WSU-NHL cell MVjHdo94fGhiaX7obYJqfGmxbjDhd5NigQ>? NGjEVIRKdmirYnn0bY9vKG:oIHj1cYFvKFeVVT3OTGwh[2WubDDndo94fGhiaX6gZUBk\WyuII\pZYJqdGm2eTDhd5NigSxiSVO1NF0zPy5zOUC3JO69VQ>? Ml\tV2FPT0WU
no-10 cell NWi2coZGT3Kxd4ToJIlvcGmkaYTpc44h[XO|YYm= NEG0fHJKdmirYnn0bY9vKG:oIHj1cYFvKG6xLUGwJINmdGxiZ4Lve5RpKGmwIHGgZ4VtdCC4aXHibYxqfHliYYPzZZktKEmFNUC9NE43Pjh2NjFOwG0> M3HEZ3NCVkeHUh?=
no-11 cell MVnHdo94fGhiaX7obYJqfGmxbjDhd5NigQ>? NWPxV3BzUW6qaXLpeIlwdiCxZjDoeY1idiCwbz2xNUBk\WyuIHfyc5d1cCCrbjDhJINmdGxidnnhZoltcXS7IHHzd4F6NCCLQ{WwQVQ4NjB{NkOg{txO M4DzW3NCVkeHUh?=
CAS-1 cell NXLqeJFoT3Kxd4ToJIlvcGmkaYTpc44h[XO|YYm= MXXJcohq[mm2aX;uJI9nKGi3bXHuJGNCWy1zIHPlcIwh\3Kxd4ToJIlvKGFiY3XscEB3cWGkaXzpeJkh[XO|YYmsJGlEPTB;MD64OFch|ryP NWrBTVRlW0GQR1XS
CCRF-CEM cell NULsRWd6T3Kxd4ToJIlvcGmkaYTpc44h[XO|YYm= NIK5TVNKdmirYnn0bY9vKG:oIHj1cYFvKEOFUl[tR2VOKGOnbHyg[5Jwf3SqIHnuJIEh[2WubDD2bYFjcWyrdImgZZN{[XluIFnDOVA:QC54NUO5NkDPxE1? NIm3cpJUSU6JRWK=
CMK cell Mkn2S5Jwf3SqIHnubIljcXSrb36gZZN{[Xl? MYPJcohq[mm2aX;uJI9nKGi3bXHuJGNOUyClZXzsJIdzd3e2aDDpckBiKGOnbHygeoli[mmuaYT5JIF{e2G7LDDJR|UxRTFwMEGzNlMh|ryP NYGwWVcxW0GQR1XS
COLO-829 cell MmHrS5Jwf3SqIHnubIljcXSrb36gZZN{[Xl? MXHJcohq[mm2aX;uJI9nKGi3bXHuJGNQVE9vOEK5JINmdGxiZ4Lve5RpKGmwIHGgZ4VtdCC4aXHibYxqfHliYYPzZZktKEmFNUC9N{4zPDJ{NjFOwG0> Mn\6V2FPT0WU
COR-L279 cell NHzlc5VIem:5dHigbY5pcWKrdHnvckBie3OjeR?= MkToTY5pcWKrdHnvckBw\iCqdX3hckBEV1JvTEK3PUBk\WyuIHfyc5d1cCCrbjDhJINmdGxidnnhZoltcXS7IHHzd4F6NCCLQ{WwQVIvODd|ODFOwG0> MmPFV2FPT0WU
CP66-MEL cell MXHHdo94fGhiaX7obYJqfGmxbjDhd5NigQ>? MlS5TY5pcWKrdHnvckBw\iCqdX3hckBEWDZ4LV3FUEBk\WyuIHfyc5d1cCCrbjDhJINmdGxidnnhZoltcXS7IHHzd4F6NCCLQ{WwQVM3NjV2OUeg{txO MX3TRW5ITVJ?
CRO-AP2 cell M3HaNGdzd3e2aDDpcohq[mm2aX;uJIF{e2G7 NVrxeG5RUW6qaXLpeIlwdiCxZjDoeY1idiCFUl:tRXAzKGOnbHyg[5Jwf3SqIHnuJIEh[2WubDD2bYFjcWyrdImgZZN{[XluIFnDOVA:Oi5|NkC4PEDPxE1? MmXsV2FPT0WU
CTV-1 cell MkXKS5Jwf3SqIHnubIljcXSrb36gZZN{[Xl? MWDJcohq[mm2aX;uJI9nKGi3bXHuJGNVXi1zIHPlcIwh\3Kxd4ToJIlvKGFiY3XscEB3cWGkaXzpeJkh[XO|YYmsJGlEPTB;MkOuPVE1PSEQvF2= NVzD[XV{W0GQR1XS
Calu-6 cell MkDkS5Jwf3SqIHnubIljcXSrb36gZZN{[Xl? M33TWWlvcGmkaYTpc44hd2ZiaIXtZY4hS2GudT22JINmdGxiZ4Lve5RpKGmwIHGgZ4VtdCC4aXHibYxqfHliYYPzZZktKEmFNUC9OFcvPTh4IN88US=> M1vhVXNCVkeHUh?=
D-247MG cell NFfBXWlIem:5dHigbY5pcWKrdHnvckBie3OjeR?= M1jMUGlvcGmkaYTpc44hd2ZiaIXtZY4hTC1{NEfNS{Bk\WyuIHfyc5d1cCCrbjDhJINmdGxidnnhZoltcXS7IHHzd4F6NCCLQ{WwQVAvPjJ6MUSg{txO NIfCO3RUSU6JRWK=
D-263MG cell M4nIUmdzd3e2aDDpcohq[mm2aX;uJIF{e2G7 MXfJcohq[mm2aX;uJI9nKGi3bXHuJGQuOjZ|TVegZ4VtdCCpcn;3eIghcW5iYTDj[YxtKH[rYXLpcIl1gSCjc4PhfUwhUUN3ME2wMlA5PTB7IN88US=> M{DR[nNCVkeHUh?=
D-336MG cell NWHkb|RbT3Kxd4ToJIlvcGmkaYTpc44h[XO|YYm= M4LPcWlvcGmkaYTpc44hd2ZiaIXtZY4hTC1|M{\NS{Bk\WyuIHfyc5d1cCCrbjDhJINmdGxidnnhZoltcXS7IHHzd4F6NCCLQ{WwQVAvPjJ6NUSg{txO Mo\HV2FPT0WU
D-392MG cell M3yxWGdzd3e2aDDpcohq[mm2aX;uJIF{e2G7 MlXSTY5pcWKrdHnvckBw\iCqdX3hckBFNTN7Ml3HJINmdGxiZ4Lve5RpKGmwIHGgZ4VtdCC4aXHibYxqfHliYYPzZZktKEmFNUC9NU41OzB|OTFOwG0> NUmweIN[W0GQR1XS
D-502MG cell MorkS5Jwf3SqIHnubIljcXSrb36gZZN{[Xl? MXjJcohq[mm2aX;uJI9nKGi3bXHuJGQuPTB{TVegZ4VtdCCpcn;3eIghcW5iYTDj[YxtKH[rYXLpcIl1gSCjc4PhfUwhUUN3ME24MlU{PDl{IN88US=> MVLTRW5ITVJ?
D-542MG cell NEH3[2VIem:5dHigbY5pcWKrdHnvckBie3OjeR?= NETGd5ZKdmirYnn0bY9vKG:oIHj1cYFvKERvNUSyUWch[2WubDDndo94fGhiaX6gZUBk\WyuII\pZYJqdGm2eTDhd5NigSxiSVO1NF0yOi5|MUWyJO69VQ>? M2rVZ3NCVkeHUh?=
DB cell NYeyWplpT3Kxd4ToJIlvcGmkaYTpc44h[XO|YYm= NVvGdnBwUW6qaXLpeIlwdiCxZjDoeY1idiCGQjDj[YxtKGe{b4f0bEBqdiCjIHPlcIwhfmmjYnnsbZR6KGG|c3H5MEBKSzVyPUS3MlE1OTdizszN NEHmeIpUSU6JRWK=
DEL cell MWDHdo94fGhiaX7obYJqfGmxbjDhd5NigQ>? NUXlVXluUW6qaXLpeIlwdiCxZjDoeY1idiCGRVygZ4VtdCCpcn;3eIghcW5iYTDj[YxtKH[rYXLpcIl1gSCjc4PhfUwhUUN3ME23MlAyQDl6IN88US=> M2nCWnNCVkeHUh?=
DMS-114 cell Mo\TS5Jwf3SqIHnubIljcXSrb36gZZN{[Xl? NYXFdnRnUW6qaXLpeIlwdiCxZjDoeY1idiCGTWOtNVE1KGOnbHyg[5Jwf3SqIHnuJIEh[2WubDD2bYFjcWyrdImgZZN{[XluIFnDOVA:PDlwOES2PEDPxE1? MnjxV2FPT0WU
DMS-153 cell M1H2Vmdzd3e2aDDpcohq[mm2aX;uJIF{e2G7 NYXZV4ZYUW6qaXLpeIlwdiCxZjDoeY1idiCGTWOtNVU{KGOnbHyg[5Jwf3SqIHnuJIEh[2WubDD2bYFjcWyrdImgZZN{[XluIFnDOVA:PDJwOUmyN{DPxE1? Ml[5V2FPT0WU
DOHH-2 cell NEL1XXZIem:5dHigbY5pcWKrdHnvckBie3OjeR?= M3nUeWlvcGmkaYTpc44hd2ZiaIXtZY4hTE:KSD2yJINmdGxiZ4Lve5RpKGmwIHGgZ4VtdCC4aXHibYxqfHliYYPzZZktKEmFNUC9OE4zOjd4NDFOwG0> NWS2VI0zW0GQR1XS
DSH1 cell NUm2XlNlT3Kxd4ToJIlvcGmkaYTpc44h[XO|YYm= NFnycWJKdmirYnn0bY9vKG:oIHj1cYFvKESVSEGgZ4VtdCCpcn;3eIghcW5iYTDj[YxtKH[rYXLpcIl1gSCjc4PhfUwhUUN3ME24MlQ{PjJ|IN88US=> MnfvV2FPT0WU
Daudi cell NXnzUJJxT3Kxd4ToJIlvcGmkaYTpc44h[XO|YYm= Ml\5TY5pcWKrdHnvckBw\iCqdX3hckBF[XWmaTDj[YxtKGe{b4f0bEBqdiCjIHPlcIwhfmmjYnnsbZR6KGG|c3H5MEBKSzVyPUKuNFk5ODJizszN M4e1[nNCVkeHUh?=
EC-GI-10 cell NI\rWXhIem:5dHigbY5pcWKrdHnvckBie3OjeR?= MV;Jcohq[mm2aX;uJI9nKGi3bXHuJGVENUeLLUGwJINmdGxiZ4Lve5RpKGmwIHGgZ4VtdCC4aXHibYxqfHliYYPzZZktKEmFNUC9OFQvOjV6OTFOwG0> MlyxV2FPT0WU
ECC4 cell NVfKWZVoT3Kxd4ToJIlvcGmkaYTpc44h[XO|YYm= MUjJcohq[mm2aX;uJI9nKGi3bXHuJGVESzRiY3XscEBoem:5dHigbY4h[SClZXzsJJZq[WKrbHn0fUBie3OjeTygTWM2OD1|Mj6xPFk3KM7:TR?= NUP1NWU3W0GQR1XS
EM-2 cell Mnq2S5Jwf3SqIHnubIljcXSrb36gZZN{[Xl? M3HQfWlvcGmkaYTpc44hd2ZiaIXtZY4hTU1vMjDj[YxtKGe{b4f0bEBqdiCjIHPlcIwhfmmjYnnsbZR6KGG|c3H5MEBKSzVyPUKuOFU2QTRizszN NGf1Z3NUSU6JRWK=
ES1 cell M4j1Vmdzd3e2aDDpcohq[mm2aX;uJIF{e2G7 MYLJcohq[mm2aX;uJI9nKGi3bXHuJGVUOSClZXzsJIdzd3e2aDDpckBiKGOnbHygeoli[mmuaYT5JIF{e2G7LDDJR|UxRTVwNUSwPFch|ryP M1TObXNCVkeHUh?=
ES3 cell MV3Hdo94fGhiaX7obYJqfGmxbjDhd5NigQ>? MlToTY5pcWKrdHnvckBw\iCqdX3hckBGWzNiY3XscEBoem:5dHigbY4h[SClZXzsJJZq[WKrbHn0fUBie3OjeTygTWM2OD12Mj60O|I6KM7:TR?= MVLTRW5ITVJ?
ES4 cell MULHdo94fGhiaX7obYJqfGmxbjDhd5NigQ>? Mlf3TY5pcWKrdHnvckBw\iCqdX3hckBGWzRiY3XscEBoem:5dHigbY4h[SClZXzsJJZq[WKrbHn0fUBie3OjeTygTWM2OD1|NT6xPVUh|ryP MU\TRW5ITVJ?
ES6 cell MkD4S5Jwf3SqIHnubIljcXSrb36gZZN{[Xl? MVvJcohq[mm2aX;uJI9nKGi3bXHuJGVUPiClZXzsJIdzd3e2aDDpckBiKGOnbHygeoli[mmuaYT5JIF{e2G7LDDJR|UxRTBwMkS3N|Mh|ryP MkHwV2FPT0WU
ES7 cell NImwNXFIem:5dHigbY5pcWKrdHnvckBie3OjeR?= MW\Jcohq[mm2aX;uJI9nKGi3bXHuJGVUPyClZXzsJIdzd3e2aDDpckBiKGOnbHygeoli[mmuaYT5JIF{e2G7LDDJR|UxRTVwMkOxNlQh|ryP NVj6dVZjW0GQR1XS
ES8 cell MXzHdo94fGhiaX7obYJqfGmxbjDhd5NigQ>? MYHJcohq[mm2aX;uJI9nKGi3bXHuJGVUQCClZXzsJIdzd3e2aDDpckBiKGOnbHygeoli[mmuaYT5JIF{e2G7LDDJR|UxRTBwOEG5NlQh|ryP MmiyV2FPT0WU
EW-18 cell M1rnU2dzd3e2aDDpcohq[mm2aX;uJIF{e2G7 NVG5XVV2UW6qaXLpeIlwdiCxZjDoeY1idiCHVz2xPEBk\WyuIHfyc5d1cCCrbjDhJINmdGxidnnhZoltcXS7IHHzd4F6NCCLQ{WwQVE{NjZ5NUmg{txO Mn\rV2FPT0WU
EW-22 cell MmPwS5Jwf3SqIHnubIljcXSrb36gZZN{[Xl? NFW0dmlKdmirYnn0bY9vKG:oIHj1cYFvKEWZLUKyJINmdGxiZ4Lve5RpKGmwIHGgZ4VtdCC4aXHibYxqfHliYYPzZZktKEmFNUC9OFcvPzl2NzFOwG0> M1fDeXNCVkeHUh?=
GCIY cell NUW3ZY41T3Kxd4ToJIlvcGmkaYTpc44h[XO|YYm= NHfzSJlKdmirYnn0bY9vKG:oIHj1cYFvKEeFSWmgZ4VtdCCpcn;3eIghcW5iYTDj[YxtKH[rYXLpcIl1gSCjc4PhfUwhUUN3ME25MlgxOzh7IN88US=> M2S3ZnNCVkeHUh?=
GDM-1 cell NHLkUGlIem:5dHigbY5pcWKrdHnvckBie3OjeR?= MUfJcohq[mm2aX;uJI9nKGi3bXHuJGdFVS1zIHPlcIwh\3Kxd4ToJIlvKGFiY3XscEB3cWGkaXzpeJkh[XO|YYmsJGlEPTB;OD6zPVE6PiEQvF2= M1q2PXNCVkeHUh?=
GI-1 cell MYLHdo94fGhiaX7obYJqfGmxbjDhd5NigQ>? Mm[4TY5pcWKrdHnvckBw\iCqdX3hckBIUS1zIHPlcIwh\3Kxd4ToJIlvKGFiY3XscEB3cWGkaXzpeJkh[XO|YYmsJGlEPTB;MD6wNFUzOyEQvF2= MUfTRW5ITVJ?
GI-ME-N cell MWXHdo94fGhiaX7obYJqfGmxbjDhd5NigQ>? M3rVRWlvcGmkaYTpc44hd2ZiaIXtZY4hT0lvTVWtUkBk\WyuIHfyc5d1cCCrbjDhJINmdGxidnnhZoltcXS7IHHzd4F6NCCLQ{WwQVAvODR7NUGg{txO M{PEeHNCVkeHUh?=
GR-ST cell M3vae2dzd3e2aDDpcohq[mm2aX;uJIF{e2G7 MWfJcohq[mm2aX;uJI9nKGi3bXHuJGdTNVOWIHPlcIwh\3Kxd4ToJIlvKGFiY3XscEB3cWGkaXzpeJkh[XO|YYmsJGlEPTB;MUOuO|kxOiEQvF2= MY\TRW5ITVJ?
GT3TKB cell M1uxWWdzd3e2aDDpcohq[mm2aX;uJIF{e2G7 NEDzOFJKdmirYnn0bY9vKG:oIHj1cYFvKEeWM2TLRkBk\WyuIHfyc5d1cCCrbjDhJINmdGxidnnhZoltcXS7IHHzd4F6NCCLQ{WwQVEvPjB|OEmg{txO NYLi[npRW0GQR1XS
HAL-01 cell M3rLZWdzd3e2aDDpcohq[mm2aX;uJIF{e2G7 MWDJcohq[mm2aX;uJI9nKGi3bXHuJGhCVC1yMTDj[YxtKGe{b4f0bEBqdiCjIHPlcIwhfmmjYnnsbZR6KGG|c3H5MEBKSzVyPU[uOlk4OTJizszN NEm3VlVUSU6JRWK=
HCC1599 cell MVvHdo94fGhiaX7obYJqfGmxbjDhd5NigQ>? NF\sOVRKdmirYnn0bY9vKG:oIHj1cYFvKEiFQ{G1PVkh[2WubDDndo94fGhiaX6gZUBk\WyuII\pZYJqdGm2eTDhd5NigSxiSVO1NF0{Py54MEGxJO69VQ>? M4n5T3NCVkeHUh?=
HCC2218 cell NYDTeIJ6T3Kxd4ToJIlvcGmkaYTpc44h[XO|YYm= NFnuTmpKdmirYnn0bY9vKG:oIHj1cYFvKEiFQ{KyNVgh[2WubDDndo94fGhiaX6gZUBk\WyuII\pZYJqdGm2eTDhd5NigSxiSVO1NF0yOy5|OEO0JO69VQ>? MY\TRW5ITVJ?
HD-MY-Z cell MUfHdo94fGhiaX7obYJqfGmxbjDhd5NigQ>? NUHocIt7UW6qaXLpeIlwdiCxZjDoeY1idiCKRD3NXU1bKGOnbHyg[5Jwf3SqIHnuJIEh[2WubDD2bYFjcWyrdImgZZN{[XluIFnDOVA:OjVwMkG0OkDPxE1? M{fVPXNCVkeHUh?=
HL-60 cell MUjHdo94fGhiaX7obYJqfGmxbjDhd5NigQ>? NGH0PJpKdmirYnn0bY9vKG:oIHj1cYFvKEiOLU[wJINmdGxiZ4Lve5RpKGmwIHGgZ4VtdCC4aXHibYxqfHliYYPzZZktKEmFNUC9NVIvOjFzNDFOwG0> MYHTRW5ITVJ?
HOP-62 cell MYnHdo94fGhiaX7obYJqfGmxbjDhd5NigQ>? NX\YN5QyUW6qaXLpeIlwdiCxZjDoeY1idiCKT2CtOlIh[2WubDDndo94fGhiaX6gZUBk\WyuII\pZYJqdGm2eTDhd5NigSxiSVO1NF0zOy57NUK3JO69VQ>? NUn1UWx1W0GQR1XS
HT cell MUjHdo94fGhiaX7obYJqfGmxbjDhd5NigQ>? NUnSPIx{UW6qaXLpeIlwdiCxZjDoeY1idiCKVDDj[YxtKGe{b4f0bEBqdiCjIHPlcIwhfmmjYnnsbZR6KGG|c3H5MEBKSzVyPUSuOFQ{OjFizszN MX3TRW5ITVJ?
HT-144 cell M{ToO2dzd3e2aDDpcohq[mm2aX;uJIF{e2G7 NYf2XlZEUW6qaXLpeIlwdiCxZjDoeY1idiCKVD2xOFQh[2WubDDndo94fGhiaX6gZUBk\WyuII\pZYJqdGm2eTDhd5NigSxiSVO1NF01NjlyNki2JO69VQ>? MnzPV2FPT0WU
HUTU-80 cell NGfhRY5Iem:5dHigbY5pcWKrdHnvckBie3OjeR?= MXfJcohq[mm2aX;uJI9nKGi3bXHuJGhWXFVvOECgZ4VtdCCpcn;3eIghcW5iYTDj[YxtKH[rYXLpcIl1gSCjc4PhfUwhUUN3ME2zMlc5QTh4IN88US=> NITEd2JUSU6JRWK=
IST-MEL1 cell NYS3Wm9NT3Kxd4ToJIlvcGmkaYTpc44h[XO|YYm= NXHSTGdwUW6qaXLpeIlwdiCxZjDoeY1idiCLU2StUWVNOSClZXzsJIdzd3e2aDDpckBiKGOnbHygeoli[mmuaYT5JIF{e2G7LDDJR|UxRTN{LkmwPFYh|ryP NYrXfGFUW0GQR1XS
IST-SL1 cell NWW4OIRPT3Kxd4ToJIlvcGmkaYTpc44h[XO|YYm= NHjsXXJKdmirYnn0bY9vKG:oIHj1cYFvKEmVVD3TUFEh[2WubDDndo94fGhiaX6gZUBk\WyuII\pZYJqdGm2eTDhd5NigSxiSVO1NF0zNjF5MEe5JO69VQ>? MlPxV2FPT0WU
IST-SL2 cell MULHdo94fGhiaX7obYJqfGmxbjDhd5NigQ>? M2PtOGlvcGmkaYTpc44hd2ZiaIXtZY4hUVOWLWPMNkBk\WyuIHfyc5d1cCCrbjDhJINmdGxidnnhZoltcXS7IHHzd4F6NCCLQ{WwQVMvOjZ4MEig{txO M{i0N3NCVkeHUh?=
K052 cell MmDFS5Jwf3SqIHnubIljcXSrb36gZZN{[Xl? M37VOmlvcGmkaYTpc44hd2ZiaIXtZY4hUzB3MjDj[YxtKGe{b4f0bEBqdiCjIHPlcIwhfmmjYnnsbZR6KGG|c3H5MEBKSzVyPUCuO|U{ODFizszN MYTTRW5ITVJ?
K5 cell NVrxdVRHT3Kxd4ToJIlvcGmkaYTpc44h[XO|YYm= M2\FbmlvcGmkaYTpc44hd2ZiaIXtZY4hUzViY3XscEBoem:5dHigbY4h[SClZXzsJJZq[WKrbHn0fUBie3OjeTygTWM2OD1|Mz61PVE2KM7:TR?= M3vUd3NCVkeHUh?=
KALS-1 cell M3jBRmdzd3e2aDDpcohq[mm2aX;uJIF{e2G7 NVPUWm0yUW6qaXLpeIlwdiCxZjDoeY1idiCNQVzTMVEh[2WubDDndo94fGhiaX6gZUBk\WyuII\pZYJqdGm2eTDhd5NigSxiSVO1NF0zQS5|OU[5JO69VQ>? MY\TRW5ITVJ?
KARPAS-422 cell MoC3S5Jwf3SqIHnubIljcXSrb36gZZN{[Xl? M2DDRWlvcGmkaYTpc44hd2ZiaIXtZY4hU0GUUFHTMVQzOiClZXzsJIdzd3e2aDDpckBiKGOnbHygeoli[mmuaYT5JIF{e2G7LDDJR|UxRTR{LkmxOFIh|ryP NF7FUmlUSU6JRWK=
KARPAS-45 cell M3L5UWdzd3e2aDDpcohq[mm2aX;uJIF{e2G7 NHznWFFKdmirYnn0bY9vKG:oIHj1cYFvKEuDUmDBV{01PSClZXzsJIdzd3e2aDDpckBiKGOnbHygeoli[mmuaYT5JIF{e2G7LDDJR|UxRTRwMUGyOFch|ryP Mm\iV2FPT0WU
KE-37 cell NFXOTHBIem:5dHigbY5pcWKrdHnvckBie3OjeR?= MUXJcohq[mm2aX;uJI9nKGi3bXHuJGtGNTN5IHPlcIwh\3Kxd4ToJIlvKGFiY3XscEB3cWGkaXzpeJkh[XO|YYmsJGlEPTB;OT64N|Uh|ryP M13oe3NCVkeHUh?=
KG-1 cell M2TpZ2dzd3e2aDDpcohq[mm2aX;uJIF{e2G7 M4TRN2lvcGmkaYTpc44hd2ZiaIXtZY4hU0dvMTDj[YxtKGe{b4f0bEBqdiCjIHPlcIwhfmmjYnnsbZR6KGG|c3H5MEBKSzVyPUKzMlk4PTdizszN NVzETG5iW0GQR1XS
KGN cell M1f3bGdzd3e2aDDpcohq[mm2aX;uJIF{e2G7 NUHGflZkUW6qaXLpeIlwdiCxZjDoeY1idiCNR16gZ4VtdCCpcn;3eIghcW5iYTDj[YxtKH[rYXLpcIl1gSCjc4PhfUwhUUN3ME2wMlU3PzR{IN88US=> MX;TRW5ITVJ?
KM12 cell MnmzS5Jwf3SqIHnubIljcXSrb36gZZN{[Xl? MlrNTY5pcWKrdHnvckBw\iCqdX3hckBMVTF{IHPlcIwh\3Kxd4ToJIlvKGFiY3XscEB3cWGkaXzpeJkh[XO|YYmsJGlEPTB;Mz61Nlk3PCEQvF2= NXLmNolNW0GQR1XS
KMOE-2 cell MVvHdo94fGhiaX7obYJqfGmxbjDhd5NigQ>? M33BWGlvcGmkaYTpc44hd2ZiaIXtZY4hU02RRT2yJINmdGxiZ4Lve5RpKGmwIHGgZ4VtdCC4aXHibYxqfHliYYPzZZktKEmFNUC9N|AvPDV2OTFOwG0> MlfiV2FPT0WU
KNS-42 cell MVzHdo94fGhiaX7obYJqfGmxbjDhd5NigQ>? MVXJcohq[mm2aX;uJI9nKGi3bXHuJGtPWy12MjDj[YxtKGe{b4f0bEBqdiCjIHPlcIwhfmmjYnnsbZR6KGG|c3H5MEBKSzVyPUiuPFE6OTVizszN MWrTRW5ITVJ?
KNS-81-FD cell M1:0W2dzd3e2aDDpcohq[mm2aX;uJIF{e2G7 NX;kN5JNUW6qaXLpeIlwdiCxZjDoeY1idiCNTmOtPFEuTkRiY3XscEBoem:5dHigbY4h[SClZXzsJJZq[WKrbHn0fUBie3OjeTygTWM2OD1|Nz60NlYh|ryP M3PhXXNCVkeHUh?=
KS-1 cell M2TZTGdzd3e2aDDpcohq[mm2aX;uJIF{e2G7 MWnJcohq[mm2aX;uJI9nKGi3bXHuJGtUNTFiY3XscEBoem:5dHigbY4h[SClZXzsJJZq[WKrbHn0fUBie3OjeTygTWM2OD1yLkCwOFYh|ryP MmXDV2FPT0WU
KU812 cell MkWwS5Jwf3SqIHnubIljcXSrb36gZZN{[Xl? MmG3TY5pcWKrdHnvckBw\iCqdX3hckBMXThzMjDj[YxtKGe{b4f0bEBqdiCjIHPlcIwhfmmjYnnsbZR6KGG|c3H5MEBKSzVyPUKzMlQ5PCEQvF2= M4rEUHNCVkeHUh?=
L-540 cell MXvHdo94fGhiaX7obYJqfGmxbjDhd5NigQ>? MV\Jcohq[mm2aX;uJI9nKGi3bXHuJGwuPTRyIHPlcIwh\3Kxd4ToJIlvKGFiY3XscEB3cWGkaXzpeJkh[XO|YYmsJGlEPTB;MkCuO|Q1PSEQvF2= NECyO|NUSU6JRWK=
LAMA-84 cell M4fxemdzd3e2aDDpcohq[mm2aX;uJIF{e2G7 MYXJcohq[mm2aX;uJI9nKGi3bXHuJGxCVUFvOESgZ4VtdCCpcn;3eIghcW5iYTDj[YxtKH[rYXLpcIl1gSCjc4PhfUwhUUN3ME2xN{43PzR{IN88US=> Ml;rV2FPT0WU
LB1047-RCC cell NHPLS3lIem:5dHigbY5pcWKrdHnvckBie3OjeR?= MlzlTY5pcWKrdHnvckBw\iCqdX3hckBNSjFyNEetVmNEKGOnbHyg[5Jwf3SqIHnuJIEh[2WubDD2bYFjcWyrdImgZZN{[XluIFnDOVA:OjhwM{i4N{DPxE1? M3XSSnNCVkeHUh?=
LB2241-RCC cell M4LYVGdzd3e2aDDpcohq[mm2aX;uJIF{e2G7 M37CUGlvcGmkaYTpc44hd2ZiaIXtZY4hVEJ{MkSxMXJESyClZXzsJIdzd3e2aDDpckBiKGOnbHygeoli[mmuaYT5JIF{e2G7LDDJR|UxRTFyLkW1N|Yh|ryP NGfnRm1USU6JRWK=
LB2518-MEL cell M3Tpcmdzd3e2aDDpcohq[mm2aX;uJIF{e2G7 M{LZ[WlvcGmkaYTpc44hd2ZiaIXtZY4hVEJ{NUG4MW1GVCClZXzsJIdzd3e2aDDpckBiKGOnbHygeoli[mmuaYT5JIF{e2G7LDDJR|UxRTFwN{G0PVbPxE1? NHH1NY9USU6JRWK=
LB831-BLC cell MnrES5Jwf3SqIHnubIljcXSrb36gZZN{[Xl? NG\meI5KdmirYnn0bY9vKG:oIHj1cYFvKEyEOEOxMWJNSyClZXzsJIdzd3e2aDDpckBiKGOnbHygeoli[mmuaYT5JIF{e2G7LDDJR|UxRTFzLkG3NlYh|ryP Mn;ZV2FPT0WU
LB996-RCC cell NXfMb|hJT3Kxd4ToJIlvcGmkaYTpc44h[XO|YYm= M4HwcmlvcGmkaYTpc44hd2ZiaIXtZY4hVEJ7OU[tVmNEKGOnbHyg[5Jwf3SqIHnuJIEh[2WubDD2bYFjcWyrdImgZZN{[XluIFnDOVA:OTJwN{SzNUDPxE1? NGnxWIRUSU6JRWK=
LC4-1 cell NUW3XVFOT3Kxd4ToJIlvcGmkaYTpc44h[XO|YYm= M1jQe2lvcGmkaYTpc44hd2ZiaIXtZY4hVEN2LUGgZ4VtdCCpcn;3eIghcW5iYTDj[YxtKH[rYXLpcIl1gSCjc4PhfUwhUUN3ME2zNk45OzRzIN88US=> NEPtcHhUSU6JRWK=
LOUCY cell M2W0dmdzd3e2aDDpcohq[mm2aX;uJIF{e2G7 MUjJcohq[mm2aX;uJI9nKGi3bXHuJGxQXUO\IHPlcIwh\3Kxd4ToJIlvKGFiY3XscEB3cWGkaXzpeJkh[XO|YYmsJGlEPTB;MT6xOVI4PiEQvF2= NVTpTJlIW0GQR1XS
LOXIMVI cell MU\Hdo94fGhiaX7obYJqfGmxbjDhd5NigQ>? NITjW41KdmirYnn0bY9vKG:oIHj1cYFvKEyRWFnNWmkh[2WubDDndo94fGhiaX6gZUBk\WyuII\pZYJqdGm2eTDhd5NigSxiSVO1NF0{OC5{MUKyJO69VQ>? NUXh[4l{W0GQR1XS
LS-123 cell M3r5WWdzd3e2aDDpcohq[mm2aX;uJIF{e2G7 MX7Jcohq[mm2aX;uJI9nKGi3bXHuJGxUNTF{MzDj[YxtKGe{b4f0bEBqdiCjIHPlcIwhfmmjYnnsbZR6KGG|c3H5MEBKSzVyPUO5MlIzPThizszN MXjTRW5ITVJ?
LU-134-A cell M4XBemdzd3e2aDDpcohq[mm2aX;uJIF{e2G7 NVzWUFd2UW6qaXLpeIlwdiCxZjDoeY1idiCOVT2xN|QuSSClZXzsJIdzd3e2aDDpckBiKGOnbHygeoli[mmuaYT5JIF{e2G7LDDJR|UxRTdwMUSwOlgh|ryP Ml;EV2FPT0WU
LU-139 cell M3T2OWdzd3e2aDDpcohq[mm2aX;uJIF{e2G7 MmXVTY5pcWKrdHnvckBw\iCqdX3hckBNXS1zM{mgZ4VtdCCpcn;3eIghcW5iYTDj[YxtKH[rYXLpcIl1gSCjc4PhfUwhUUN3ME2yNk4zOThizszN NH6z[VNUSU6JRWK=
LXF-289 cell MWrHdo94fGhiaX7obYJqfGmxbjDhd5NigQ>? M1f6PWlvcGmkaYTpc44hd2ZiaIXtZY4hVFiILUK4PUBk\WyuIHfyc5d1cCCrbjDhJINmdGxidnnhZoltcXS7IHHzd4F6NCCLQ{WwQVE4NjR|NUJOwG0> M3;VUnNCVkeHUh?=
MC116 cell NY\kTpB{T3Kxd4ToJIlvcGmkaYTpc44h[XO|YYm= M4LETmlvcGmkaYTpc44hd2ZiaIXtZY4hVUNzMU[gZ4VtdCCpcn;3eIghcW5iYTDj[YxtKH[rYXLpcIl1gSCjc4PhfUwhUUN3ME20OU4xQDRzIN88US=> MlnaV2FPT0WU
MDA-MB-134-VI cell NIXUOolIem:5dHigbY5pcWKrdHnvckBie3OjeR?= M1P2RWlvcGmkaYTpc44hd2ZiaIXtZY4hVUSDLV3CMVE{PC2YSTDj[YxtKGe{b4f0bEBqdiCjIHPlcIwhfmmjYnnsbZR6KGG|c3H5MEBKSzVyPUO5MlI1QDZizszN NEXRbZpUSU6JRWK=
MFH-ino cell M3L2emdzd3e2aDDpcohq[mm2aX;uJIF{e2G7 M3LvbGlvcGmkaYTpc44hd2ZiaIXtZY4hVU[KLXnuc{Bk\WyuIHfyc5d1cCCrbjDhJINmdGxidnnhZoltcXS7IHHzd4F6NCCLQ{WwQVAvPjR|OEOg{txO NFvpVVJUSU6JRWK=
MHH-NB-11 cell M3\lXGdzd3e2aDDpcohq[mm2aX;uJIF{e2G7 M{n0R2lvcGmkaYTpc44hd2ZiaIXtZY4hVUiKLV7CMVEyKGOnbHyg[5Jwf3SqIHnuJIEh[2WubDD2bYFjcWyrdImgZZN{[XluIFnDOVA:OC5yNk[5JO69VQ>? NFfyTHBUSU6JRWK=
ML-2 cell M37B[Gdzd3e2aDDpcohq[mm2aX;uJIF{e2G7 NGjVdmFKdmirYnn0bY9vKG:oIHj1cYFvKE2OLUKgZ4VtdCCpcn;3eIghcW5iYTDj[YxtKH[rYXLpcIl1gSCjc4PhfUwhUUN3ME2zMlQxOzB2IN88US=> NFXJT2hUSU6JRWK=
MOLT-13 cell NXzHV4F3T3Kxd4ToJIlvcGmkaYTpc44h[XO|YYm= NVXpO4JRUW6qaXLpeIlwdiCxZjDoeY1idiCPT1zUMVE{KGOnbHyg[5Jwf3SqIHnuJIEh[2WubDD2bYFjcWyrdImgZZN{[XluIFnDOVA:PC52M{[1N{DPxE1? MnfEV2FPT0WU
MOLT-16 cell MUPHdo94fGhiaX7obYJqfGmxbjDhd5NigQ>? MlPvTY5pcWKrdHnvckBw\iCqdX3hckBOV0yWLUG2JINmdGxiZ4Lve5RpKGmwIHGgZ4VtdCC4aXHibYxqfHliYYPzZZktKEmFNUC9OE4yOTF4MzFOwG0> M3;QbHNCVkeHUh?=
MOLT-4 cell M3PkRmdzd3e2aDDpcohq[mm2aX;uJIF{e2G7 NH;GXIFKdmirYnn0bY9vKG:oIHj1cYFvKE2RTGStOEBk\WyuIHfyc5d1cCCrbjDhJINmdGxidnnhZoltcXS7IHHzd4F6NCCLQ{WwQVE1NjRzMkSg{txO NHHIOphUSU6JRWK=
MPP-89 cell M{DWZWdzd3e2aDDpcohq[mm2aX;uJIF{e2G7 NHLXVoNKdmirYnn0bY9vKG:oIHj1cYFvKE2SUD24PUBk\WyuIHfyc5d1cCCrbjDhJINmdGxidnnhZoltcXS7IHHzd4F6NCCLQ{WwQVEvOjV7MkKg{txO NVOwVG9rW0GQR1XS
MRK-nu-1 cell M2nJPWdzd3e2aDDpcohq[mm2aX;uJIF{e2G7 MlzGTY5pcWKrdHnvckBw\iCqdX3hckBOWktvboWtNUBk\WyuIHfyc5d1cCCrbjDhJINmdGxidnnhZoltcXS7IHHzd4F6NCCLQ{WwQVAvPTd3N{Kg{txO M1zqNnNCVkeHUh?=
MSTO-211H cell NWTIdnFFT3Kxd4ToJIlvcGmkaYTpc44h[XO|YYm= MYfJcohq[mm2aX;uJI9nKGi3bXHuJG1UXE9vMkGxTEBk\WyuIHfyc5d1cCCrbjDhJINmdGxidnnhZoltcXS7IHHzd4F6NCCLQ{WwQVEzNjh4OTFOwG0> NF7WflRUSU6JRWK=
MV-4-11 cell NVXYclNoT3Kxd4ToJIlvcGmkaYTpc44h[XO|YYm= NU\q[ZQ2UW6qaXLpeIlwdiCxZjDoeY1idiCPVj20MVEyKGOnbHyg[5Jwf3SqIHnuJIEh[2WubDD2bYFjcWyrdImgZZN{[XluIFnDOVA:OC5zM{mxOUDPxE1? M3PnRXNCVkeHUh?=
NALM-6 cell MofES5Jwf3SqIHnubIljcXSrb36gZZN{[Xl? M{HURmlvcGmkaYTpc44hd2ZiaIXtZY4hVkGOTT22JINmdGxiZ4Lve5RpKGmwIHGgZ4VtdCC4aXHibYxqfHliYYPzZZktKEmFNUC9NU42PjFyOTFOwG0> NUTKeZlJW0GQR1XS
NB1 cell NXrDT3I2T3Kxd4ToJIlvcGmkaYTpc44h[XO|YYm= NH\ae3ZKdmirYnn0bY9vKG:oIHj1cYFvKE6EMTDj[YxtKGe{b4f0bEBqdiCjIHPlcIwhfmmjYnnsbZR6KGG|c3H5MEBKSzVyPUOuPFQ{PjlizszN MW\TRW5ITVJ?
NB10 cell NG[4NndIem:5dHigbY5pcWKrdHnvckBie3OjeR?= M4e4PGlvcGmkaYTpc44hd2ZiaIXtZY4hVkJzMDDj[YxtKGe{b4f0bEBqdiCjIHPlcIwhfmmjYnnsbZR6KGG|c3H5MEBKSzVyPUCuNVM6OTVizszN MkDUV2FPT0WU
NB12 cell MVfHdo94fGhiaX7obYJqfGmxbjDhd5NigQ>? MkO2TY5pcWKrdHnvckBw\iCqdX3hckBPSjF{IHPlcIwh\3Kxd4ToJIlvKGFiY3XscEB3cWGkaXzpeJkh[XO|YYmsJGlEPTB;MU[uOVY2PiEQvF2= MVvTRW5ITVJ?
NB13 cell M3raVWdzd3e2aDDpcohq[mm2aX;uJIF{e2G7 NYjufnU5UW6qaXLpeIlwdiCxZjDoeY1idiCQQkGzJINmdGxiZ4Lve5RpKGmwIHGgZ4VtdCC4aXHibYxqfHliYYPzZZktKEmFNUC9Nk4{OTJ5ODFOwG0> NEPVW2pUSU6JRWK=
NB17 cell MVfHdo94fGhiaX7obYJqfGmxbjDhd5NigQ>? MlfCTY5pcWKrdHnvckBw\iCqdX3hckBPSjF5IHPlcIwh\3Kxd4ToJIlvKGFiY3XscEB3cWGkaXzpeJkh[XO|YYmsJGlEPTB;Mz61PFA2OSEQvF2= NYfSb|ViW0GQR1XS
NB6 cell NF3D[llIem:5dHigbY5pcWKrdHnvckBie3OjeR?= M2jtXWlvcGmkaYTpc44hd2ZiaIXtZY4hVkJ4IHPlcIwh\3Kxd4ToJIlvKGFiY3XscEB3cWGkaXzpeJkh[XO|YYmsJGlEPTB;MD61PVEyPCEQvF2= NFTDcJpUSU6JRWK=
NCCIT cell NUP5N|BjT3Kxd4ToJIlvcGmkaYTpc44h[XO|YYm= M1H1WWlvcGmkaYTpc44hd2ZiaIXtZY4hVkOFSWSgZ4VtdCCpcn;3eIghcW5iYTDj[YxtKH[rYXLpcIl1gSCjc4PhfUwhUUN3ME20NU45PDV|IN88US=> NHPSRXlUSU6JRWK=
NCI-H1155 cell M{GydWdzd3e2aDDpcohq[mm2aX;uJIF{e2G7 Ml\DTY5pcWKrdHnvckBw\iCqdX3hckBPS0lvSEGxOVUh[2WubDDndo94fGhiaX6gZUBk\WyuII\pZYJqdGm2eTDhd5NigSxiSVO1NF0yPC5|NEC4JO69VQ>? Mn7UV2FPT0WU
NCI-H1304 cell MlP0S5Jwf3SqIHnubIljcXSrb36gZZN{[Xl? MU\Jcohq[mm2aX;uJI9nKGi3bXHuJG5EUS2KMUOwOEBk\WyuIHfyc5d1cCCrbjDhJINmdGxidnnhZoltcXS7IHHzd4F6NCCLQ{WwQVEyNjh7OEKg{txO MVXTRW5ITVJ?
NCI-H1355 cell NVHBfItwT3Kxd4ToJIlvcGmkaYTpc44h[XO|YYm= MYPJcohq[mm2aX;uJI9nKGi3bXHuJG5EUS2KMUO1OUBk\WyuIHfyc5d1cCCrbjDhJINmdGxidnnhZoltcXS7IHHzd4F6NCCLQ{WwQVQvQTRzMTFOwG0> MW\TRW5ITVJ?
NCI-H1395 cell MX\Hdo94fGhiaX7obYJqfGmxbjDhd5NigQ>? NXTXN2p7UW6qaXLpeIlwdiCxZjDoeY1idiCQQ1mtTFE{QTViY3XscEBoem:5dHigbY4h[SClZXzsJJZq[WKrbHn0fUBie3OjeTygTWM2OD1{Mj64O|k2KM7:TR?= NVnsSoxEW0GQR1XS
NCI-H1417 cell NWDEbW1ST3Kxd4ToJIlvcGmkaYTpc44h[XO|YYm= M{jnVWlvcGmkaYTpc44hd2ZiaIXtZY4hVkOLLVixOFE4KGOnbHyg[5Jwf3SqIHnuJIEh[2WubDD2bYFjcWyrdImgZZN{[XluIFnDOVA:PS54N{WyNkDPxE1? M37QSHNCVkeHUh?=
NCI-H1436 cell MYjHdo94fGhiaX7obYJqfGmxbjDhd5NigQ>? M1LLNmlvcGmkaYTpc44hd2ZiaIXtZY4hVkOLLVixOFM3KGOnbHyg[5Jwf3SqIHnuJIEh[2WubDD2bYFjcWyrdImgZZN{[XluIFnDOVA:Oy56NEGwNUDPxE1? M3n2dXNCVkeHUh?=
NTERA-S-cl-D1 cell MnzPS5Jwf3SqIHnubIljcXSrb36gZZN{[Xl? MV3Jcohq[mm2aX;uJI9nKGi3bXHuJG5VTVKDLWOtZ4wuTDFiY3XscEBoem:5dHigbY4h[SClZXzsJJZq[WKrbHn0fUBie3OjeTygTWM2OD1zMj64PVM2KM7:TR?= M2\lSHNCVkeHUh?=
JiyoyeP-2003 cell MkjzS5Jwf3SqIHnubIljcXSrb36gZZN{[Xl? MXHJcohq[mm2aX;uJI9nKGi3bXHuJGpqgW:7ZWCtNlAxOyClZXzsJIdzd3e2aDDpckBiKGOnbHygeoli[mmuaYT5JIF{e2G7LDDJR|UxRTN4Lk[yPFQh|ryP M3rKbHNCVkeHUh?=

... Click to View More Cell Line Experimental Data

In vivo Oral administration of GSK269962A produced a profound dose-dependent reduction of systemic blood pressure in spontaneously hypertensive rats. The reduction of blood pressure was acute and substantial. The maximal effect on blood pressure was observed approximately 2 h after oral gavages. The reduction of blood pressure was accompanied by an acute, dose-dependent increase in heart rate, presumably due to the activation of baroreflex mechanism[1]. ROCK inhibition with the use of GSK 269962 in the 10 mg/kg dose, in turn, triggered an increase in VV(voided volume), PVR(post-void residual), VT(volume threshold), VE(voiding efficiency), ICI(intercontraction interval), BC(bladder compliance), and VTNVC(volume threshold to elicit NVC). The inhibition of the ROCK pathway through GSK 269962 appeared to have no effect on either HR(heart rate), SBP(systolic blood pressure), MBP(systolic blood pressure), or DBP(diastolic blood pressure)[2]. NVC:nonvoiding contractions.

Protocol

Cell Research:[1]
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  • Cell lines: Human primary smooth muscle cells
  • Concentrations: 3 μM
  • Incubation Time: 150 min
  • Method: Human primary smooth muscle cells were serum-starved(cells were grown on coverslips, and at approximately 50% confluence, they were serum-starved overnight) and stimulated with AngII (100 nM) for 2 h. ROCK inhibitors (3 μM for SB-772077-B or GSK269962A) were added 30 min before AngII stimulation, and cells were fixed and stained with rhodamine phalloidin. Confocal images of actin stain were obtained.
    (Only for Reference)
Animal Research:[2]
+ Expand
  • Animal Models: female Wistar rats
  • Formulation: saline
  • Dosages: 5 or 10 mg/kg
  • Administration: intra-arterially
    (Only for Reference)

Solubility (25°C)

In vitro DMSO 100 mg/mL (164.72 mM)
Ethanol 6 mg/mL (9.88 mM)
Water Insoluble

* Please note that Selleck tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.

Chemical Information

Molecular Weight 607.06
Formula

C29H30N8O5.HCl

CAS No. 850664-21-0(free base)
Storage powder
in solvent
Synonyms GSK269962B, GSK269962, GSK 269962

Bio Calculators

Molarity Calculator

Molarity Calculator

Calculate the mass, volume or concentration required for a solution. The Selleck molarity calculator is based on the following equation:

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

  • Mass
    Concentration
    Volume
    Molecular Weight

*When preparing stock solutions, please always use the batch-specific molecular weight of the product found on the via label and MSDS / COA (available on product pages).

Dilution Calculator

Dilution Calculator

Calculate the dilution required to prepare a stock solution. The Selleck dilution calculator is based on the following equation:

Concentration (start) x Volume (start) = Concentration (final) x Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2 ( Input Output )

  • C1
    V1
    C2
    V2

* When preparing stock solutions always use the batch-specific molecular weight of the product found on the vial label and MSDS / COA (available online).

The Serial Dilution Calculator Equation

  • Serial Dilutions

  • Computed Result

  • C1=C0/X C1: LOG(C1):
    C2=C1/X C2: LOG(C2):
    C3=C2/X C3: LOG(C3):
    C4=C3/X C4: LOG(C4):
    C5=C4/X C5: LOG(C5):
    C6=C5/X C6: LOG(C6):
    C7=C6/X C7: LOG(C7):
    C8=C7/X C8: LOG(C8):
Molecular Weight Calculator

Molecular Weight Calculator

Enter the chemical formula of a compound to calculate its molar mass and elemental composition:

Total Molecular Weight: g/mol

Tip: Chemical formula is case sensitive. C10H16N2O2 c10h16n2o2

Instructions to calculate molar mass (molecular weight) of a chemical compound:

To calculate molar mass of a chemical compound, please enter its chemical formula and click 'Calculate'.

Definitions of molecular mass, molecular weight, molar mass and molar weight:

Molecular mass (molecular weight) is the mass of one molecule of a substance and is expressed in the unified atomic mass units (u). (1 u is equal to 1/12 the mass of one atom of carbon-12)
Molar mass (molar weight) is the mass of one mole of a substance and is expressed in g/mol.

Molarity Calculator

Mass Concentration Volume Molecular Weight

Tech Support

Answers to questions you may have can be found in the inhibitor handling instructions. Topics include how to prepare stock solutions, how to store inhibitors, and issues that need special attention for cell-based assays and animal experiments.

Handling Instructions

Tel: +1-832-582-8158 Ext:3

If you have any other enquiries, please leave a message.

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ROCK Signaling Pathway Map

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Cell Lines Assay Type Concentration Incubation Time Formulation Activity Description PMID