Clotrimazole

Catalog No.S1606

Clotrimazole is a synthetic, antifungal and broad-spectrum derivate of imidazole.

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In DMSO USD 130 In stock
USD 97 In stock
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Clotrimazole Chemical Structure

Clotrimazole Chemical Structure
Molecular Weight: 344.84

Validation & Quality Control

Quality Control & MSDS

Related Compound Libraries

Clotrimazole is available in the following compound libraries:

Product Information

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Product Description

Biological Activity

Clotrimazole(Canesten) is a synthetic, antifungal and broad-spectrum derivate of imidazole. Clotrimazole inhibits biosynthesis of sterols, particularly inhibiting ergosterol, which is an essential component of the fungal cell membrane, thereby damaging and affecting the permeability of the cell membrane. This results in the  leakage and the loss of essential intracellular compounds, and eventually causes the lysis of cell.  [1, 2]

Chemical Information

Download Clotrimazole SDF
Molecular Weight (MW) 344.84
Formula

C22H17ClN2

CAS No. 23593-75-1
Storage 3 years -20℃Powder
6 months-80℃in DMSO
Syonnyms Lotrimin, Mycelex, Canesten
Solubility (25°C) * In vitro DMSO 11 mg/mL (31 mM)
Water <1 mg/mL (<1 mM)
Ethanol 69 mg/mL (200 mM)
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Selleck tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
Chemical Name

Preparing Stock Solutions

Stock Solution (1ml DMSO) 1mM 10mM 20mM 30mM
Mass(mg) 0.34484 3.4484 6.8968 10.3452

Research Area

Tech Support & FAQs

Answers to questions you may have can be found in the inhibitor handling instructions. Topics include how to prepare stock solutions, how to store inhibitors, and issues that need special attention for cell-based assays and animal experiments.

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