Clotrimazole

Catalog No.S1606

Clotrimazole is a synthetic, antifungal and broad-spectrum derivate of imidazole.

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In DMSO USD 130 In stock
USD 97 In stock
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Clotrimazole Chemical Structure

Clotrimazole Chemical Structure
Molecular Weight: 344.84

Validation & Quality Control

Quality Control & MSDS

Related Compound Libraries

Clotrimazole is available in the following compound libraries:

Product Information

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Product Description

Biological Activity

Clotrimazole(Canesten) is a synthetic, antifungal and broad-spectrum derivate of imidazole. Clotrimazole inhibits biosynthesis of sterols, particularly inhibiting ergosterol, which is an essential component of the fungal cell membrane, thereby damaging and affecting the permeability of the cell membrane. This results in the  leakage and the loss of essential intracellular compounds, and eventually causes the lysis of cell.  [1, 2]

Clinical Trial Information( data from http://clinicaltrials.gov)

NCT Number Recruitment Conditions Sponsor
/Collaborators
Start Date Phases
NCT02113800 Not yet recruiting Poorly Differentiated Neuroendocrine Carcinoma,|Neuroendocrine Carcinoma, Grade 3|Neuroendocrine Carcinoma, Grade 1 [Well-differentiated Neuroendocrine Carcinoma] That Switched to G3|Neuroendocrine Carcinoma, Grade 2 [Moderately Differentiated Neuroendocrine Carcinoma] That Switched to G3|Neuroendocrine Tumor, Grade 3 AIO-Studien-gGmbH|Assign Data Management and Biostatistics GmbH|Novartis 2014-09 Phase 2
NCT01489202 Not yet recruiting Coronary Artery Disease University of Roma La Sapienza 2014-09 Phase 4
NCT01762657 Not yet recruiting Type 1 Diabetes Perle Bioscience, LLC. 2014-09 Phase 3
NCT02120469 Not yet recruiting Estrogen Receptor-negative Breast Cancer|HER2-negative Breast Cancer|Progesterone Receptor-negative Breast Cancer|Recurrent Breast Cancer|Stage IV Breast Cancer|Triple-negative Breast Cancer City of Hope Medical Center|National Cancer Institute (NCI) 2014-10 Phase 1
NCT02042326 Not yet recruiting Arteriovenous Malformations (Stage II to IV) Centre Hospitalier Universitaire, Amiens 2015-01 Phase 2

Chemical Information

Download Clotrimazole SDF
Molecular Weight (MW) 344.84
Formula

C22H17ClN2

CAS No. 23593-75-1
Storage 3 years -20℃Powder
6 months-80℃in DMSO
Synonyms
Solubility (25°C) * In vitro DMSO 11 mg/mL (31 mM)
Water <1 mg/mL (<1 mM)
Ethanol 69 mg/mL (200 mM)
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Selleck tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
Chemical Name

Research Area

Tech Support & FAQs

Answers to questions you may have can be found in the inhibitor handling instructions. Topics include how to prepare stock solutions, how to store inhibitors, and issues that need special attention for cell-based assays and animal experiments.

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