S1123

Abiraterone(CB-7598)


Technical Data:
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Abiraterone(CB-7598)
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M.Wt: 349.51
Formula: C24H31NO
Solubility: DMSO
Purity: >99%
Storage: at -20℃ 2 years
CAS No.: 154229-19-3
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Price and Availability of Abiraterone(CB-7598):

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5mg / $170In Stock
25mg / $570In Stock
100mg / $1670In Stock
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Biological Activity of Abiraterone(CB-7598):

Abiraterone (CB-7598) is a potent steroidal cytochrome P450 17alpha-hydroxylase-17,20-lyase  (CYP17) inhibitor with an IC50 at 4 nM.
Abiraterone (CB-7598 is currently undergoing phase II clinical trials as a potential compound for the treatment of prostate cancer. In preclinical studies, abiraterone (CB-7598) has demonstrated the ability to selectively inhibit the target enzyme, resulting in inhibition of testosterone production in both the adrenals and the testes. Clinical studies demonstrated that CYP17 blockade by abiraterone acetate is safe and has significant antitumor activity in CRPC (castration-resistant prostate cancer). [1][2]



Quality Control:

MSDS
Batch S112301: H-NMR  HPLC  COA
Batch S112302: H-NMR  COA
Batch S112303: H-NMR  COA
Batch S112304: H-NMR  HPLC  COA


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