Naringenin Chemical Structure
Apigenin is a potent CYP2C9 inhibitor with an IC50 of 23 pM.
Baicalein is a CYP2C9 and prolyl endopeptidase inhibitor.
Sodium Danshensu is a mono sodium of danshensu which is a compound isolated from Salvia miltiorrhiza Bge.
Apigenin is a potent CYP2C9 inhibitor with an IC50 of 23 pM.
Baicalein is a CYP2C9 and prolyl endopeptidase inhibitor.
Icariin is a flavonol and PDE5 inhibitor with IC50 of 1.0, 0.75, and 1.1 μM for PDE5A1, A2, and A3, respectively.
Luteolin is a PDE4 inhibitor and a general phosphodiesterase inhibitor, and an Interleukin 6 inhibitor.
Naringenin is a flavonoid that is considered to have a bioactive effect on human health as antioxidant, free radical scavenger, anti-inflammatory, carbohydrate metabolism promoter, and immune system modulator. Naringenin is the predominant flavanone in grapefruit. This substance has also been shown to reduce oxidative damage to DNA in vitro. Naringenin found in grapefruit juice has been shown to have an inhibitory effect on the human cytochrome P450 isoform CYP1A2, which can change pharmacokinetics in a human (or orthologous) host of several popular agents in an adverse manner, even resulting in carcinogens of otherwise harmless substances. [1]
| Molecular Weight (WM): | 272.25 |
|---|---|
| Formula: | C15H12O5 |
| CAS No.: | 480-41-1 |
| Synonyms: |
N/A
|
| Dissolve in (25°C): | DMSO ≥55mg/mL |
| Water <1mg/mL | |
| Ethanol ≥55mg/mL | |
| Storage: | 2 years-20°CPowder |
| 1 week-4°Cin DMSO | |
| 1 month-80°in DMSO |
A collection of 864 bioactive compounds
A collection of 481 inhibitors
A collection of 194 kinase inhibitors
A collection of 85 tyrosine kinase inhibitors.
A collection of 426 FDA approved drugs
A collection of 139 natural products
A collection of 40 chemotherapeutic agents
A unique collection of 17 small molecule modulators
A unique collection of 47 small molecule inhibitors
A unique collection of 63 GPCR small molecules
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