Research Area
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Baicalein Chemical Structure
Voriconazole
Voriconazole (VFEND) is a triazole antifungal medication that is generally used to treat serious, invasive fungal infections.
Cytochrome P450 14a-demethylase inhibitor 1a
Cytochrome P450 14a-demethylase inhibitor 1a is an antifungal agent and an analog of fluconazole with an MIC80 of 3.9 ng/ml against Candida albicans.
Cytochrome P450 14a-demethylase inhibitor 1b
Cytochrome P450 14a-demethylase inhibitor 1b is an antifungal agent and an analog of fluconazole with an MIC80 of 3.9 ng/ml against Candida albicans and Microsporum gypseum.
Cytochrome P450 14a-demethylase inhibitor 1c
Cytochrome P450 14a-demethylase inhibitor 1c is an antifungal agent and an analog of fluconazole with an MIC80 of 15.6 ng/ml against Candida albicans and Microsporum gypseum.
Cytochrome P450 14a-demethylase inhibitor 1d
Cytochrome P450 14a-demethylase inhibitor 1d is an antifungal agent and an analog of fluconazole with an MIC80 of 15.6 ng/ml against Candida albicans and Microsporum gypseum.
Cytochrome P450 14a-demethylase inhibitor 1e
Cytochrome P450 14a-demethylase inhibitor 1e is an antifungal agent and an analog of fluconazole with an MIC80 of 15.6 ng/ml against Candida albicans.
Cytochrome P450 14a-demethylase inhibitor 1f
Cytochrome P450 14a-demethylase inhibitor 1f is an antifungal agent and an analog of fluconazole with an MIC80 of 15.6 ng/ml against Candida albicans.
Cytochrome P450 14a-demethylase inhibitor 1g
Cytochrome P450 14a-demethylase inhibitor 1g is an antifungal agent and an analog of fluconazole with an MIC80 of 0.25 µg/ml against Candida albicans.
Cytochrome P450 14a-demethylase inhibitor 1h
Cytochrome P450 14a-demethylase inhibitor 1h is an antifungal agent and an analog of fluconazole with an MIC80 of 15.6 ng/ml against Microsporum gypseum.
Cytochrome P450 14a-demethylase inhibitor 1i
Cytochrome P450 14a-demethylase inhibitor 1i is an antifungal agent and an analog of fluconazole with an MIC80 of 62.5 ng/ml against Candida albicans.
Biological Activity
Baicalein is a CYP2C9 and prolyl endopeptidase inhibitor. It is a flavone, a type of flavonoid, originally isolated from the roots of Scutellaria baicalensis. It is also reported in Oroxylum indicum or Indian trumpetflower. It is the aglycone of baicalin.The flavonoid has been shown to inhibit certain types of lipoxygenases and act as an anti-inflammatory agent. [1]
References on Baicalein
- [1] http://en.wikipedia.org/wiki/Baicalein ;
Product Information
| Molecular Weight (WM): | 270.24 |
|---|---|
| Formula: | C15H10O5 |
| CAS No.: | 491-67-8 |
| Synonyms: |
N/A
|
| Dissolve in (25°C): | DMSO ≥54mg/mL |
| Water <1mg/mL | |
| Ethanol <1mg/mL | |
| Storage: | 2 years-20°CPowder |
| 1 week-4°Cin DMSO | |
| 1 month-80°in DMSO |
Quality Control & MSDS
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