Sodium Danshensu

Sodium Danshensu is a mono sodium of danshensu which is a compound isolated from Salvia miltiorrhiza Bge.

Catalog No.S2401
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Sodium Danshensu Chemical Structure
Molecular Weight: 220.15

Related Compound Libraries

Sodium Danshensu is available in the following compound libraries:

Product Information

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Product Description

Biological Activity

Sodium Danshensu is a mono sodium of danshensu which is a compound isolated from Salvia miltiorrhiza Bge. Sodium danshensucan can significantly regulate PXR and CYP3A4. In thoracic arteries under basal tonus, sodium danshensu (0.3-3 g/L) produced a dose-dependent transient contraction. In phenylephrine-precontracted thoracic arteries with or without endothelium, low concentration (0.1-0.3 g/L) of sodium danshensu produced a weak contraction, while high concentrations (1-3 g/L) produced a pronounced vasodilator after a transient vasocontraction. Pre-incubation with sodium danshensu could inhibit vessel contraction induced by phenylephrine and potassium chloride in a concentration-dependent way. Sodium danshensu inhibited phenylephrine- and CaCl2-induced vasoconstriction in Ca2+-free medium. Pre-incubation with tetraethylammonium, a non-selective K+ channel blocker, and apamin, a small-conductance calcium-activated K+ channel blocker partially antagonized the relaxation response induced by sodium danshensu. [1][2]

Chemical Information

Download Sodium Danshensu SDF
Molecular Weight (MW) 220.15
Formula

C9H9O5.Na

CAS No. 67920-52-9, 23028-17-3
Synonyms N/A
Storage 2 years -20°CPowder
2 weeks4°Cin DMSO
6 months-80°Cin DMSO
Chemical Name sodium 3-(3,4-dihydroxyphenyl)-2-hydroxypropanoate

Research Area

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