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S1141
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17-AAG (Tanespimycin) |
17-AAG (Tanespimycin) is a potent HSP90 inhibitor with IC50of 5 nM. |
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S1069
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AUY922 (NVP-AUY922) |
NVP-AUY922 (VER-52296) is a highly potent HSP90 inhibitor for HSP90α and HSP90β with IC50 of 13 nM and 21 nM, respectively. |
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S1052
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Elesclomol |
Elesclomol (STA-4783) is a novel potent oxidative stress inducer that illicits pro-apoptosis events among tumor cells.. |
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S1159
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Ganetespib (STA-9090) |
Ganetespib is an HSP90 inhibitor with IC50 of 4 nM in OSA 8 cells. |
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S1142
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17-DMAG HCl (Alvespimycin) |
17-DMAG (Alvespimycin, KOS-1022, NSC 707545) is a potent HSP90 inhibitor with IC50 of 62 nM. |
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S2713
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Geldanamycin |
Geldanamycin is a natural existing HSP90 inhibitor with Kd of 1.2 μM. |
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S1163
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AT13387 |
AT13387 is a selective potent Hsp90 inhibitor with IC50 of 18 nM in A375 cells. |
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S2685
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KW-2478 |
KW-2478 is a nonansamycin HSP90 inhibitor with IC50 of 3.8 nM. |
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S2639
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SNX-2112 |
SNX-2112 selectively binds to the ATP pocket of HSP90α and HSP90β with Ka of 30 nM and 30 nM, respectively. |
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S2656
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PF-04929113 (SNX-5422) |
PF-04929113 (SNX-5422) is a potent and selective HSP90 inhibitor with Kd of 41 nM and also inhibits Her-2 degradation with IC50 of 37 nM. |
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S1498
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NVP-BEP800 |
NVP-BEP800 is a novel, fully synthetic HSP90β inhibitor with IC50 of 58 nM. |
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S1175
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BIIB021 |
BIIB021 is a novel inhibitor of HSP90 with Ki and EC50 of 1.7 nM and 38 nM, respectivley. |
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