Reverse Transcriptase

Signaling Pathway Map

Research Area

  • Inhibitory Selectivity
  • Solubility
Catalog No. Product Name Solubility(25°C)
Water DMSO Alcohol
S1401 Tenofovir 2 mg/mL 4 mg/mL <1 mg/mL
S1400 Tenofovir Disoproxil Fumarate <1 mg/mL 100 mg/mL 44 mg/mL
S1704 Emtricitabine 49 mg/mL 49 mg/mL 9 mg/mL
S1252 Entecavir Hydrate <1 mg/mL 59 mg/mL <1 mg/mL
S1718 Adefovir Dipivoxil <1 mg/mL 100 mg/mL 100 mg/mL
S3606 Fangchinoline <1 mg/mL 100 mg/mL 4 mg/mL
S1742 Nevirapine <1 mg/mL 53 mg/mL <1 mg/mL
S1702 Didanosine <1 mg/mL 47 mg/mL <1 mg/mL
S1706 Lamivudine 46 mg/mL 46 mg/mL <1 mg/mL
S1398 Stavudine (d4T) <1 mg/mL 45 mg/mL 15 mg/mL
S1651 Telbivudine 48 mg/mL 48 mg/mL 2 mg/mL
S3080 Etravirine (TMC125) <1 mg/mL 42 mg/mL <1 mg/mL
S2579 Zidovudine 53 mg/mL 53 mg/mL 18 mg/mL
S1719 Zalcitabine 42 mg/mL 7 mg/mL <1 mg/mL
S3165 Abacavir sulfate 36 mg/mL <1 mg/mL <1 mg/mL
S2914 Dapivirine (TMC120) <1 mg/mL 34 mg/mL <1 mg/mL
S3076 Foscarnet Sodium 3 mg/mL 7 mg/mL <1 mg/mL
S7303 Rilpivirine <1 mg/mL 73 mg/mL <1 mg/mL
S4187 Salicylanilide <1 mg/mL 43 mg/mL 18 mg/mL
S4685 Efavirenz <1 mg/mL 63 mg/mL 63 mg/mL
S7856 Tenofovir Alafenamide (GS-7340) <1 mg/mL 95 mg/mL 95 mg/mL
Catalog No. Information Product Use Citations Product Validations
S1401

Tenofovir

Tenofovir blocks reverse transcriptase and hepatitis B virus infections.

S1400

Tenofovir Disoproxil Fumarate

Tenofovir Disoproxil Fumarate belongs to a class of antiretroviral drugs, it inhibits the activity of HIV reverse transcriptase by competing with the natural substrate deoxyadenosine 5’-triphosphate and, after incorporation into DNA, by DNA chain termination.

S1704

Emtricitabine

Emtricitabine (FTC) is a new nucleoside agent that has activity against both human immunodeficiency virus (HIV) and hepatitis B virus. It is a reverse transcriptase inhibitor. Intracellular half-life is 39 h.

S1252

Entecavir Hydrate

Entecavir, a new deoxyguanine nucleoside analogue, is a selective inhibitor of the replication of the hepatitis B virus (HBV).

S1718

Adefovir Dipivoxil

Adefovir Dipivoxil is a reverse transcriptase inhibitor, used in the treatment of chronic hepatitis B virus (HBV).

S3606New

Fangchinoline

Fangchinoline, a bisbenzylisoquinoline alkaloid, is a novel HIV-1 inhibitor with pain-relieving, blood pressure-depressing, and antibiotic activities.

S1742

Nevirapine

Nevirapine is a non-nucleoside reverse transcriptase inhibitor (NNRTI) used to treat HIV-1 infection and AIDS.

S1702

Didanosine

Didanosine is a reverse transcriptase inhibitor with an IC50 of 0.49 μM.

S1706

Lamivudine

Lamivudine is a potent nucleoside analog reverse transcriptase inhibitor, used for treatment of chronic HBV and HIV/AIDS. It works by blocking the HIV reverse transcriptase and hepatitis B virus polymerase.

S1398

Stavudine (d4T)

Stavudine (d4T) is a nucleoside analog reverse transcriptase inhibitor (NARTI) active against HIV.

S1651

Telbivudine

Telbivudine is a potent, and selective HBV reverse transcriptase inhibitor, used to treat HBV infection.

S3080

Etravirine (TMC125)

Etravirine (TMC125) is a non-nucleoside reverse transcriptase inhibitor (NNRTI) used for the treatment of HIV.

S2579

Zidovudine

Zidovudine (ZDV) is a nucleoside analogue reverse transcriptase inhibitor, used to treat HIV.

S1719

Zalcitabine

Zalcitabine is a nucleoside analog HIV reverse transcriptase inhibitor (NARTI).

S3165

Abacavir sulfate

Abacavir is a commonly used nucleoside analogue with potent antiviral activity against HIV-1.

S2914

Dapivirine (TMC120)

Dapivirine (TMC120) is a non-nucleoside inhibitor for HIV reverse transcriptase with IC50 of 24 nM, inhibits a broad panel of HIV-1 isolates from different classes, inclucing a wide range of NNRTI-resistant isolates. Phase 3.

S3076

Foscarnet Sodium

Foscarnet Sodium inhibits viral RNA polymerases, reverse transcriptase, and DNA polymerases through noncompetitive inhibition with dNTPs.

S7303

Rilpivirine

Rilpivirine is a non-nucleoside reverse transcriptase inhibitor (NNRTI), and used to treat HIV-1 infection.

S4187

Salicylanilide

Salicylanilides are a group of compounds with a wide range of biological activities including antiviral potency, antibacterial (including antimycobacterial) and antifungal activities.

S4685

Efavirenz

Efavirenz is a synthetic non-nucleoside reverse transcriptase (RT) inhibitor with antiviral activity.

S7856

Tenofovir Alafenamide (GS-7340)

Tenofovir Alafenamide (GS-7340) is a prodrug of tenofovir, which is a reverse transcriptase inhibitor, used to treat HIV and Hepatitis B.

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