Tenofovir (Viread) Chemical Structure
Elvitegravir (EVG, JTK-303, GS-9137) is an inhibitor of the integrase enzyme and inhibits HIV-1 IIIB, HIV-2 EHO and HIV-2 ROD with IC50 values of 0.7 nM, 2.8 nM and 1.4 nM, respectively.
Maraviroc is a CCR5 antagonist. Maraviroc was active (IC90) at low nanomolar concentrations against HIV-1 Ba-L.
Raltegravir (MK-0518) is an HIV integrase inhibitor, IC95 for HIV-1 in 50% normal human serum = 33 nM.
Vicriviroc Malate is a CCR5(cellular coreceptor 5) inhibitor, in vitro activity against HIV (IC90<13 nM)
BMS-707035 is an HIV-1 integrase (IN) inhibitor.
Stavudine is a nucleoside analog reverse transcriptase inhibitor (NARTI) active against HIV.
Emtricitabine (Emtriva) is a nucleoside reverse transcriptase inhibitor with an IC50 of 27.7 μM.
S/GSK1349572 (GSK 1349572) is a novel potent integrase inhibitor with an IC50 of 2.7 nM in vitro.
Tenofovir (Viread) is a drug used to treat human immunodeficiency virus (HIV) infection. Tenofovir is an antiviral drug called a nucleotide reverse transcriptase inhibitor. Tenofovir may reduce the amount of HIV in the blood and increase the number of CD4 cells (T-cells) in the blood. Tenofovir is used in combination with other drugs to treat the HIV virus. Tenofovir will not cure or prevent HIV infection or AIDS. [1]
| Molecular Weight (WM): | 287.21 |
|---|---|
| Formula: | C9H14N5O4P |
| CAS No.: | 147127-20-6 |
| Synonyms: |
N/A
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| Dissolve in (25°C): | DMSO ≥4mg/mL |
| Water ≥2mg/mL | |
| Ethanol <1mg/mL | |
| Storage: | 2 years-20°CPowder |
| 1 week-4°Cin DMSO | |
| 1 month-80°in DMSO |
A collection of 864 bioactive compounds
A collection of 481 inhibitors
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A collection of 85 tyrosine kinase inhibitors.
A collection of 426 FDA approved drugs
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A unique collection of 17 small molecule modulators
A unique collection of 47 small molecule inhibitors
A unique collection of 63 GPCR small molecules
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