Bcl-6

Cat.No. Product Name Information Product Use Citations Product Validations
S8591 FX1 FX1 is a selective BCL6 BTB inhibitor with an IC50 value of 35 μM in reporter assays. This compound shows great selectivity against a panel of 50 different kinases. 10 μM of this chemical fails to significantly inhibit of any of these kinases. It induces apoptosis.
Frontiers in Oncology, September 22 2025, 15:1616519
Life Science Alliance, October 27 2025, e202503335
Frontiers in Immunology, May 09 2025, 16:1558845
S6937 BI-3802 BI-3802 is a highly potent oncogenic transcription factor BCL6 degrader with strong de-repression of target genes anti-proliferative effects. This compound inhibits the BTB domain of BCL6 with IC50 of ≤3 nM. It exhibits antitumor activity.
Adv Sci (Weinh), 2025, 12(31):e01284
Phytomedicine, 2024, 133:155944
Cancer Research, 2023, 3624-3635
S8735 BI-3812 BI-3812 is a highly potent and efficacious BCL6 inhibitor probe compound with an IC50 less than 3 nM.
Journal of the American Chemical Society, 2025, 44739-44758
American Journal of Transplantation, 2024, 2157-2173
Haematologica, 2022, 10.3324/haematol.2022.280879
S8250 79-6 (CID5721353) 79-6 (CID5721353), a BCL6 inhibitor, has a Kd value of 138 μM.
Cell Reports Medicine, 2022, 100744
Cell Rep Med, 2022, 3(9):100744