Survivin

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Survivin Inhibitors (1)

water-soluble

Cat.No. Product Name Information Product Use Citation Customer Product Validation
S1130 YM155 (Sepantronium Bromide) YM155 (Sepantronium Bromide) is a potent survivin suppressant by inhibiting Survivin promoter activity with IC50 of 0.54 nM in HeLa-SURP-luc and CHO-SV40-luc cells; does not significantly inhibit SV40 promoter activity, but is observed to slightly inhibit the interaction of Survivin with XIAP. Phase 2.
  • Nat Chem Biol, 2014, 10(9):768-73
  • Leukemia, 2012, 26(4):623-32
  • Proc Natl Acad Sci USA, 2012, 109(2):600-5

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Cat.No. Product Name Solubility (25°C)
Water DMSO Ethanol
S1130 YM155 (Sepantronium Bromide) 89 mg/mL 55 mg/mL 6 mg/mL
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