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S1172
|
JNJ 26854165 (Serdemetan) |
JNJ 26854165 (Serdemetan) is an orally bioavailable HDM2 antagonist. |
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S2781
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RITA (NSC 652287) |
RITA (NSC 652287) is a DNA damaging agent with IC50 of 2 nM and 20 nM in A498 and TK-10 cells. |
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S2929
|
Pifithrin-α |
Pifithrin-α is an inhibitor of p53, inhibiting p53-dependent transactivation of p53-responsive genes. |
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S8000
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Tenovin-1 |
Tenovin-1 is a p53 activator and acts through inhibition of protein-deacetylating activities of SirT1 and SirT2. |
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S2678
|
NSC-207895 (XI-006) |
NSC-207895 suppresses MDMX with IC50 of 2.5 µM, leading to enhanced p53 stabilization/activation and DNA damage. |
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