Research Area
Product Type
PDE Inhibitors
- Cat.No
- Product Name
- Information
- Publications
- Customer Reviews
- S1455
- Cilomilast (SB-207499)
- Cilomilast (SB-207499) is among the first of a new generation of PDE4 inhibitors (Ki ≈100 nM).
(0)
(0)
- S1550
- Pimobendan (Vetmedin)
- Pimobendan (Vetmedin) is a selective inhibitor of phosphodiesterase III (PDE III) with an IC50 of 0.32 μM.
- (0)
-
(1)
- S2620
- GSK256066
- GSK256066 is an exceptionally high affinity and selective PDE4 inhibitor with an IC50 of 3.2 pM for PDE4B.
- (0)
- (0)
- S1430
- Rolipram
- Rolipram is a PDE4-inhibitor and an anti-inflammatory agent.
- (0)
- (0)
- S2320
- Luteolin
- Luteolin is a PDE4 inhibitor and a general phosphodiesterase inhibitor, and an Interleukin 6 inhibitor.
- (0)
- (0)
- S2312
- Icariin
- Icariin is a flavonol and PDE5 inhibitor with IC50 of 1.0, 0.75, and 1.1 μM for PDE5A1, A2, and A3, respectively.
- (0)
- (0)
- S2127
- S-(+)-Rolipram
- S-(+)-Rolipram is a less active enantiomer of the PDE4 inhibitor with an EC50 of 1.0 μM
- (0)
- (0)
- S2687
- PF-2545920
- PF-2545920 a highly selective and potent PDE10A inhibitor with an IC50 of 0.37 nM.
- (0)
- (0)