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S1512
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Tadalafil (Cialis) |
Tadalafil is a PDE-5 inhibitor with IC50 of 1.8 nM. |
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S1431
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Sildenafil citrate |
Sildenafil citrate is an agent used to treat erectile dysfunction and pulmonary arterial hypertension (PAH). |
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S2620
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GSK256066 |
GSK256066 is a selective PDE4B inhibitor with IC50 of 3.2 pM. |
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S1430
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Rolipram |
Rolipram is a PDE4-inhibitor and an anti-inflammatory agent. |
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S1455
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Cilomilast (SB-207499) |
Cilomilast (SB-207499) is a potent LPDE4 and HPDE4 inhibitor with IC50 of 100 nM and 120 nM, respectively. |
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S8034
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Apremilast (CC-10004) |
Apremilast (CC-10004) is a potent PDE4 and TNF-α inhibitor with IC50 of 74 nM and 77 nM, respectively. |
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S4019
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Avanafil |
Avanafil is a highly selective PDE5 inhibitor with IC50 of 1 nM. |
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S2131
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Roflumilast (Daxas) |
Roflumilast(Daxas) is a selective, long-acting the enzyme PDE-4 inhibitor with an IC50 of 0.8 nM. |
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S2515
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Vardenafil Hydrochloride Trihydrate (Vivanza) |
Vardenafil Hydrochloride Trihydrate (Vivanza) is a new type PDE inhibitor with IC50 of 0.7 and 180 nM for PDE5 and PDE1, respectively. |
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S3172
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Anagrelide HCl |
Anagrelide is a drug used for the treatment of essential thrombocytosis. |
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S2687
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PF-2545920 |
PF-2545920 is a potent and selective PDE10A inhibitor with IC50 of 0.37 nM. |
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S2127
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S-(+)-Rolipram |
S-(+)-Rolipram inhibits human monocyte cyclic AMP-specific PDE4 with IC50 of 0.75 μM. |
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S1673
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Aminophylline (Truphylline) |
Aminophylline(Phyllocontin, Truphylline) is a competitive nonselective phosphodiesterase inhibitor with an IC50 of 0.12 mM and also a nonselective adenosine receptor antagonist. |
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S1550
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Pimobendan (Vetmedin) |
Pimobendan is a selective inhibitor of PDE3 with IC50 of 0.32 μM. |
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S1504
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Dyphylline (Dilor) |
Dyphylline(Dilor, Lufyllin, diprophylline) is a xanthine derivative with bronchodilator and vasodilator effects. |
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S1294
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Cilostazol |
Cilostazol is a potent cyclic nucleotide phosphodiesterase type 3 (PDE3) inhibitor with IC50 of 0.2 μM and inhibitor of adenosine uptake. |
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