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Icariin

Catalog No.S2312
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Icariin Chemical Structure

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Biological Activity

Icariin is a flavonol and PDE5 inhibitor with IC50 of 1.0, 0.75, and 1.1 μM for PDE5A1, A2, and A3, respectively. It enhances the production of bioactive nitric oxide, as well as mimicking the effects of testosterone. It also shows antioxidant, antidepressant and nootropic effects in animal studies, as well as stimulating osteoblast activity in bone tissue which has been linked to a possible therapeutic role in the treatment of osteoporosis. [1][2]

References on Icariin
  • [1] http://en.wikipedia.org/wiki/Icariin ;
  • [2] Urology. 2006 Dec;68(6):1350-4.
Molecular Weight (WM): 676.66
Formula:

C33H40O15

CAS No.: 489-32-7
Synonyms:
N/A
Dissolve in (25°C): DMSO ≥135mg/mL 
Water <1mg/mL 
Ethanol <1mg/mL 
Storage: 2 years-20°CPowder
1 week-4°Cin DMSO
1 month-80°in DMSO

Quality Control & MSDS

Research Area

Related Inhibitors

Recommended Screening Libraries

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