Product Categories

Wnt/beta-catenin Inhibitors

Cat.No.	Product Name	Information	Product Citations
S1180	XAV-939	XAV-939 is a selective Wnt β-catenin-mediated transcription inhibitor for TNKS1 and TNKS2 with IC50 of 11 nM and 4 nM, respectively.	Toxicol Sci, 2013, ahead of print PLoS One, 2012, 7(12), e50457 Mol Cancer, 2011, 10, 66
S2662	ICG-001	ICG-001 specifically binds to CBP with IC50 of 3 μM.
S7085	IWP-2	IWP-2 is an inhibitor of Wnt processing and secretion with IC50 of 27 nM.
S7086	IWR-1-endo	IWR-1 (endo-IWR 1) is a Wnt pathway inhibitor with IC50 of 180 nM.

Cat.No.	Product Name	Solubility (25°C)
S1180	XAV-939	<1 mg/mL	15 mg/mL	<1 mg/mL
S2662	ICG-001	<1 mg/mL	110 mg/mL	45 mg/mL